Inhalation
View article: The effectiveness of combined anesthesia with the use of inhaled anesthetic xenon and intravenous anesthetic dexmedetomidine during plastic surgery
The effectiveness of combined anesthesia with the use of inhaled anesthetic xenon and intravenous anesthetic dexmedetomidine during plastic surgery Open
A clinically and pharmacologically sound and rational combination of various anesthetics is of increasing interest in scientific and practical activities, as it makes it possible to more effectively achieve targeted therapy within the crit…
View article: Sub-chronic exposure to crude acetylene results in the development of deleterious cardio metabolic changes in Sprague Dawley rats
Sub-chronic exposure to crude acetylene results in the development of deleterious cardio metabolic changes in Sprague Dawley rats Open
Objective Calcium carbide-derived acetylene is widely used as an artificial fruit ripening agent despite its potential health risks. This study aimed to investigate the effects of sub-chronic exposure to crude acetylene on cardiometabolic …
View article: High-flow Oxygen and Nitric Oxide inhalation versus high-flow oxygen alone to prevent intubation in hypoxaemic Respiratory failure (HONOR): a pilot randomised controlled trial protocol
High-flow Oxygen and Nitric Oxide inhalation versus high-flow oxygen alone to prevent intubation in hypoxaemic Respiratory failure (HONOR): a pilot randomised controlled trial protocol Open
Background When conventional oxygen therapies fail, endotracheal intubation and invasive mechanical ventilation are the current standard of care in patients with acute hypoxaemic respiratory failure. However, invasive mechanical ventilatio…
View article: A predictive formula for the indication of airway management in burn patients
A predictive formula for the indication of airway management in burn patients Open
The developed formulas had good performance. In clinical practice, burn patients with screened risk factors (age > 49.5 years, later than 14.9 h, BI of total body > 14.5, BI of head/face/neck > 2.8, and with inhalation injury) were suspect…
View article: A Prospective Study of Inhaled Therapy Prescribing, Pressurised Metered-Dose Inhaler (pMDI) Technique Assessment, and Inhaler Concordance Monitoring Among Hospitalised Adult Patients With Airways Disease
A Prospective Study of Inhaled Therapy Prescribing, Pressurised Metered-Dose Inhaler (pMDI) Technique Assessment, and Inhaler Concordance Monitoring Among Hospitalised Adult Patients With Airways Disease Open
View article: Sex‐specific impact of repeated adolescent vapour exposure to JWH‐018 on dopamine response, behaviour and pharmacokinetics across adolescence and adulthood
Sex‐specific impact of repeated adolescent vapour exposure to JWH‐018 on dopamine response, behaviour and pharmacokinetics across adolescence and adulthood Open
Background and Purpose Alarming trends show that vaping e‐cigarettes containing synthetic cannabinoid receptor agonists, such as JWH‐018, is increasing among youth. However, the effects of these trends are unclear in both sexes. We therefo…
View article: Efficacy of Bispectral Index‐Guided Sevoflurane Administration in Pediatric Patients Undergoing General Anesthesia: An up‐To‐Date Systematic Review and Meta‐Analysis
Efficacy of Bispectral Index‐Guided Sevoflurane Administration in Pediatric Patients Undergoing General Anesthesia: An up‐To‐Date Systematic Review and Meta‐Analysis Open
Background The bispectral index (BIS) represents a promising tool for monitoring the depth of hypnosis. However, its utility in guiding sevoflurane administration during general anesthesia in pediatric patients is not well known. Methods W…
View article: Preliminary Studies on the Distribution of Stable Pb and Pb-210 in the Maternal and Fetal Portions of Human Placentas
Preliminary Studies on the Distribution of Stable Pb and Pb-210 in the Maternal and Fetal Portions of Human Placentas Open
Fetal growth and survival are solely dependent on the placenta, making the characterization of toxic elements in this tissue crucial for understanding exposure during pregnancy. Stable lead (Pb) and Pb-210 are toxic elements of particular …
View article: Implementation of a stepped anti-inflammatory reliever therapy intervention with budesonide-formoterol 160/4·5 mcg by Turbuhaler versus usual care for adults presenting during exacerbations of obstructive lung disease suggestive of asthma or chronic obstructive pulmonary disease in a resource-limited setting: an open-label, cluster randomised trial
Implementation of a stepped anti-inflammatory reliever therapy intervention with budesonide-formoterol 160/4·5 mcg by Turbuhaler versus usual care for adults presenting during exacerbations of obstructive lung disease suggestive of asthma or chronic obstructive pulmonary disease in a resource-limited setting: an open-label, cluster randomised trial Open
Summary: Background: In resource-limited countries, chronic respiratory disease is common, and access to diagnosis and to the multiple medications in asthma and chronic obstructive pulmonary disease guidelines is limited. Building on a pre…
View article: Efficacy of ethylmethylhydroxypyridine succinate derivative in a model of intermittent hypoxia in comparison with the reference drug
Efficacy of ethylmethylhydroxypyridine succinate derivative in a model of intermittent hypoxia in comparison with the reference drug Open
Introduction. Intermittent hypoxia (IH) promotes oxygen free radical oxidation, which may precede many diseases. Decreased physical activity, ischaemic processes in organs and disturbances at the cellular level, may be a consequence of int…
View article: Soft Palate and Uvula Thermal Burn Injury in an Adolescent Following Recreational Inhalation of Nitrous Oxide
Soft Palate and Uvula Thermal Burn Injury in an Adolescent Following Recreational Inhalation of Nitrous Oxide Open
View article: Impact of formulation and process parameters on the stability and bioactivity of RNA-loaded lipid nanoparticles during nebulization
Impact of formulation and process parameters on the stability and bioactivity of RNA-loaded lipid nanoparticles during nebulization Open
During the pandemic, lipid nanoparticles (LNPs) became widely established as RNA nanocarriers, and hold the promise of future targeting of a broad variety of previously untreatable diseases. LNPs are mostly administered invasively via intr…
View article: Glycyrrhiza glabra Linn (Liquorice) – Herbal Cough Candy
Glycyrrhiza glabra Linn (Liquorice) – Herbal Cough Candy Open
The present study deals with the formulation and evaluation of herbal cough candy prepared by traditional medicinal agents such as Liquorice, Tulsi, Neem, Clove, Ginger, Citric acid, Glycerine, and Sucrose. Cough is the common respir…
View article: Glycyrrhiza glabra Linn (Liquorice) – Herbal Cough Candy
Glycyrrhiza glabra Linn (Liquorice) – Herbal Cough Candy Open
The present study deals with the formulation and evaluation of herbal cough candy prepared by traditional medicinal agents such as Liquorice, Tulsi, Neem, Clove, Ginger, Citric acid, Glycerine, and Sucrose. Cough is the common respiratory …
View article: Safety and Efficacy of Alfentanil Compared to Sufentanil in Target- Controlled Infusion During Flexible Bronchoscopy: A Randomized Controlled Trial
Safety and Efficacy of Alfentanil Compared to Sufentanil in Target- Controlled Infusion During Flexible Bronchoscopy: A Randomized Controlled Trial Open
Background Optimal anesthetic management during flexible bronchoscopy requires balancing sedation, safety, and procedural efficiency. Target-controlled infusion (TCI) systems offer precise drug delivery, but comparative data between opioid…
View article: Original data of Western Blot
Original data of Western Blot Open
OVA group mice and OVAPBM group mice were sensitized with an intraperitoneal injection of 100 μL phosphate-buffered saline (PBS) containing 100 μg of ovalbumin (OVA; Sigma, A5253) and 5 mg of aluminum hydroxide (Sigma, A6435). Two weeks la…
View article: Development of periodic breathing in awake healthy individuals under controlled progressive hypoxia
Development of periodic breathing in awake healthy individuals under controlled progressive hypoxia Open
The aim of this study was to better understand the ventilatory response to controlled progressive hypoxia in healthy individuals and identify factors influencing the development of periodic breathing under hypoxic conditions. The study was…
View article: Three-Dimensional Look-Locker Method for Free-Breathing T1 Mapping of Oxygen-Enhanced Pulmonary Magnetic Resonance Imaging
Three-Dimensional Look-Locker Method for Free-Breathing T1 Mapping of Oxygen-Enhanced Pulmonary Magnetic Resonance Imaging Open
Oxygen-enhanced magnetic resonance imaging (OE-MRI) enables non-invasive assessment of lung function by measuring longitudinal relaxation time (T1) changes induced by alternating inhalation of room air and pure oxygen. In this study, the p…
View article: Original data of Western Blot
Original data of Western Blot Open
Antibodies against β-Actin (catalog number 21338) was purchased from ABclonal. Antibodies against NF-κB p65 (catalog number 8242S) and antibodies against Phospho-NF-κB p65 (catalog number 3033S) were purchased from CST.The Western blot ima…
View article: Occupational Asthma Due to Hair Dyes Containing Para‐Amino Compounds
Occupational Asthma Due to Hair Dyes Containing Para‐Amino Compounds Open
Background Persulfate salts in hair bleaches are a well‐documented cause of occupational asthma (OA) among hairdressers, but little information is available on OA caused by hair products containing other low‐molecular‐weight chemicals. The…
View article: Prophylactic effect of Abelmoschus esculentus seed extract on some key parameters in asthmatic mice: bioactive compound analysis and histopathological examination
Prophylactic effect of Abelmoschus esculentus seed extract on some key parameters in asthmatic mice: bioactive compound analysis and histopathological examination Open
Seeds from Abelmoschus esculentus have strong anti-inflammatory properties and may effectively treat inflammatory diseases. This study explores the therapeutic potential of A. esculentus seed extract on bioactive components, hematological …
View article: Next-generation high-throughput in vitro exposure system for early hazard ranking and comparative assessment of cigarette smoke and heated tobacco aerosols
Next-generation high-throughput in vitro exposure system for early hazard ranking and comparative assessment of cigarette smoke and heated tobacco aerosols Open
Background Accuracy, along with reproducibility and transferability, are essential attributes of modern in vitro inhalation exposure systems to reliably assess the hazard potential of complex aerosols and remain aligned with advancements i…
View article: Radon exposure delays the development of skin lesions in a mouse model of psoriasis
Radon exposure delays the development of skin lesions in a mouse model of psoriasis Open
Introduction The chronic inflammatory skin disease psoriasis vulgaris is characterized by itchy plaques, often accompanied by life-threatening comorbidities severely impairing the quality of life and cause high socioeconomic costs. Despite…
View article: Development of Control Methods for Submicron Particulate Matter Emissions and Inhalation Exposure from Cosmetic Spray Products
Development of Control Methods for Submicron Particulate Matter Emissions and Inhalation Exposure from Cosmetic Spray Products Open
View article: Original data of Western Blot
Original data of Western Blot Open
Antibodies against β-Actin (catalog number 21338) was purchased from ABclonal. Antibodies against NF-κB p65 (catalog number 8242S) and antibodies against Phospho-NF-κB p65 (catalog number 3033S) were purchased from CST.The Western blot ima…
View article: Methoxyflurane as a volatile anesthetic and its place in modern pain management: a narrative review
Methoxyflurane as a volatile anesthetic and its place in modern pain management: a narrative review Open
Background: Methoxyflurane (C3H4Cl2F2O, Penthrox), introduced initially as a volatile anesthetic in the 1960s, was later discontinued as a general anesthetic due to nephrotoxicity. However, recent studies have highlighted its significant a…
View article: Effect of hydrogen inhalation on functional characteristics and intestinal gas biomarkers in wrestlers during physical exercise
Effect of hydrogen inhalation on functional characteristics and intestinal gas biomarkers in wrestlers during physical exercise Open
Purpose of the study : to investigate the effect of periodic hydrogen inhalations for one month on the main performance characteristics, lactate levels and other biochemical parameters determined in the blood of young wrestlers after physi…
View article: Thyroid doses estimated for a cohort of people exposed to fallout from atmospheric nuclear weapons testing at the semipalatinsk nuclear test site, Kazakhstan
Thyroid doses estimated for a cohort of people exposed to fallout from atmospheric nuclear weapons testing at the semipalatinsk nuclear test site, Kazakhstan Open
Thyroid doses were estimated for a cohort of 3,183 individuals who were exposed to fallout from atmospheric nuclear weapons tests conducted at the Semipalatinsk Nuclear Test Site (SNTS), Kazakhstan, between 1949 and 1962. The study partici…
View article: Naso -Pulmonary drug Delivery Systems: A novel and emerging platform for Targeted Respiratory and systemic Therapy
Naso -Pulmonary drug Delivery Systems: A novel and emerging platform for Targeted Respiratory and systemic Therapy Open
Naso pulmonary Drug delivery system (NPDS) has produced a significant interest as simple, reliable, and promising Approach for the systemic administration of pharmaceuticals. The intranasal route can improve patient c…
View article: Naso -Pulmonary drug Delivery Systems: A novel and emerging platform for Targeted Respiratory and systemic Therapy
Naso -Pulmonary drug Delivery Systems: A novel and emerging platform for Targeted Respiratory and systemic Therapy Open
Naso pulmonary Drug delivery system (NPDS) has produced a significant interest as simple, reliable, and promising Approach for the systemic administration of pharmaceuticals. The intranasal route can improve patient convenience, comfort, a…