Echinococcus granulosus
View article
International consensus on terminology to be used in the field of echinococcoses Open
Echinococcoses require the involvement of specialists from nearly all disciplines; standardization of the terminology used in the field is thus crucial. To harmonize echinococcosis terminology on sound scientific and linguistic grounds, th…
View article
Hepatic Echinococcal Cysts: A Review Open
Cystic echinococcosis (CE) is a widely endemic helminthic disease caused by infection with metacestodes (larval stage) of the Echinococcus granulosus tapeworm. E. granulosus are common parasites in certain parts of the world, and are prese…
View article
Current status of diagnosis and treatment of hepatic echinococcosis Open
Echinococcus granulosus (E. granulosus) and Echinococcus multilocularis (E. multilocularis) infections are the most common parasitic diseases that affect the liver. The disease course is typically slow and the patients tend to remain asymp…
View article
Echinococcus granulosus sensu lato and Echinococcus multilocularis: A review Open
Echinococcus spp. have a global distribution and are found on every continent except Antarctica. Infections with these parasites are considered extremely serious, contributing to significant morbidity and mortality in addition to substanti…
View article
Hepatic echinococcosis: A review Open
Cystic echinococcosis (CE) is a widely endemic helminthic disease caused by infection with metacestodes (larval stage) of the Echinococcus granulosus tapeworm and transmitted by dogs. E. granulosus are common parasites in certain parts of …
View article
Progress in the pharmacological treatment of human cystic and alveolar echinococcosis: Compounds and therapeutic targets Open
Human cystic and alveolar echinococcosis are helmintic zoonotic diseases caused by infections with the larval stages of the cestode parasites Echinococcus granulosus and E. multilocularis, respectively. Both diseases are progressive and ch…
View article
Review on Epidemiology and Public Health Significance of Hydatidosis Open
Hydatidosis is a zoonotic parasitic disease caused by larval stages (hydatid cysts) of cestodes belonging to the genus Echinococcus and the family Taeniidae. Hydatid cyst, which is the larval stage of Echinococcus, is a bladder-like cyst f…
View article
Hepatic hydatid cyst – diagnose and treatment algorithm Open
Introduction: the hydatic disease, caused by the larvae of Echinococcus granulosus, is a serious disease, potentially lethal, which can be found anywhere in the world, but especially in endemic areas such as the Mediterranean Basin, Austra…
View article
Pulmonary hydatid cyst: Review of literature Open
Echinococcosis is a rare infectious disease in human being that occurs by the larval stages of taeniid cestodes of the genus Echinococcus. Human cystic echinococcosis is the most common presentation. The liver is the most common site of ec…
View article
Immunology of cystic echinococcosis (hydatid disease) Open
Develop tools for functional genomics; characterize immunologically interesting proteins suggested by genomic information; analyse infection in broader context of granulomatous responses; identify molecules secreted/excreted by intact larv…
View article
Extracellular vesicles from Echinococcus granulosus larval stage: Isolation, characterization and uptake by dendritic cells Open
The secretion of extracellular vesicles (EVs) in helminth parasites is a constitutive mechanism that promotes survival by improving their colonization and adaptation in the host tissue. In the present study, we analyzed the production of E…
View article
Epidemiology of echinococcosis in Iran: a systematic review and meta-analysis Open
Background Echinococcosis is a zoonotic disease caused by the larval stages of taeniid cestodes of the genus Echinococcus . The two major types of infection in humans are cystic echinococcosis (CE) or hydatidosis and alveolar echinococcosi…
View article
<i>Echinococcus granulosus</i>genotypes in Iran: a systematic review Open
Cystic echinococcosis (CE) caused by Echinococcus granulosus sensu lato (s.l.) is a significant zoonosis, especially in developing countries of the Middle East, with many studies focusing on CE genotypes in Iran. We performed a systematic …
View article
Molecular phylogeny based on six nuclear genes suggests that <i>Echinococcus granulosus sensu lato</i> genotypes G6/G7 and G8/G10 can be regarded as two distinct species Open
Tapeworms of the species complex of Echinococcus granulosus sensu lato ( s. l. ) are the cause of a severe zoonotic disease – cystic echinococcosis, which is listed among the most severe parasitic diseases in humans and is prioritized by t…
View article
Epidemiological distribution of Echinococcus granulosus s.l. infection in human and domestic animal hosts in European Mediterranean and Balkan countries: A systematic review Open
Cystic echinococcosis (CE) is a neglected zoonosis caused by infection with the cestode Echinococcus granulosus sensu lato. We carried out a systematic literature review on E. granulosus s.l. human and animal (cattle, sheep, dog) infection…
View article
Long-read sequencing reveals a 4.4 kb tandem repeat region in the mitogenome of Echinococcus granulosus (sensu stricto) genotype G1 Open
We report what we consider to be the first complete mt genome of E. granulosus genotype G1 and characterise all repeat regions in this genome. The numbers, sizes, sequences and functions of tandem repeat regions remain to be studied in dif…
View article
Prevalence of cystic echinococcosis in Iran: a systematic review and meta-analysis Open
As a significant zoonosis, cystic echinococcosis (CE) is endemic in some parts of the world, such as the Middle East. There are studies on the prevalence of this infection in animal and human reservoirs in Iran; hence, we conducted this me…
View article
Pathology of Echinococcosis Open
Infection of humans by the larval stage of the tapeworms Echinococcus granulosus sensu lato or Echinococcus multilocularis causes the life-threatening zoonoses cystic echinococcosis (CE) and alveolar echinococcosis (AE). Although cystic li…
View article
First description of Echinococcus ortleppi infection in China Open
To our knowledge, this report describes the first identification of a human E. ortleppi infection in China. Our data broaden the geographical distribution of this rarely reported species of Echinococcus.
View article
A systematic review of medicinal plants used against Echinococcus granulosus Open
Cystic echinococcosis (CE) is a zoonotic helminthiasis caused by different species of the genus Echinococcus, and is a major economic and public health concern worldwide. Synthetic anthelmintics are most commonly used to control CE, howeve…
View article
Extracellular vesicles derived from Echinococcus granulosus hydatid cyst fluid from patients: isolation, characterization and evaluation of immunomodulatory functions on T cells Open
Cystic echinococcosis is a chronic and complex zoonotic disease. The mechanisms underlying the parasite's establishment, growth and persistence are not completely understood, and are thought be modulated by a crosstalk through extracellula…
View article
The Echinococcus canadensis (G7) genome: a key knowledge of parasitic platyhelminth human diseases Open
This is the first work that addresses Echinococcus comparative genomics. The resources presented here will promote the study of mechanisms of parasite development as well as new tools for drug discovery. The availability of a high-quality …
View article
Antihydatic and immunomodulatory effects of Punica granatum peel aqueous extract in a murine model of echinococcosis Open
Our results indicate an antihydatic scolicidal effect and immunomodulatory properties of PGE, suggesting its potential therapeutic role against Echinococcus granulosus infection.
View article
First description of Echinococcus ortleppi and cystic echinococcosis infection status in Chile Open
Cystic echinococcosis (CE), a parasitic disease caused by the cestode Echinococcus granulosus sensu lato (s.l.), is a worldwide zoonotic infection. Although endemic in Chile, information on the molecular characteristics of CE in livestock …
View article
Scolicidal agents for protoscolices of Echinococcus granulosus hydatid cyst: Review of literature Open
Hydatid cyst is the larval stage of dog tape worm Echinococcus granulosus . Protoscolices are parasite larvae that develop into adult worms in the final host intestine. During surgical treatment of human hydatidsosis spillage of live proto…
View article
A multi-method and structure-based in silico vaccine designing against Echinococcus granulosus through investigating enolase protein Open
Introduction: Hydatid disease is a ubiquitous parasitic zoonotic disease, which causes different medical, economic and serious public health problems in some parts of the world. The causal organism is a multi-stage parasite named Echinococ…
View article
High-resolution phylogeography of zoonotic tapeworm<i>Echinococcus granulosus</i>sensu stricto genotype G1 with an emphasis on its distribution in Turkey, Italy and Spain Open
SUMMARY Echinococcus granulosus is the causative agent of cystic echinococcosis. The disease is a significant global public health concern and human infections are most commonly associated with E. granulosus sensu stricto (s. s.) genotype …
View article
Hydatid cyst fluid promotes peri-cystic fibrosis in cystic echinococcosis by suppressing miR-19 expression Open
Our study provides new evidence for the intervention of miRNAs in the regulation of fibrosis in infectious diseases; it suggests that E. granulosus can inhibit miR-19 liver expression and promote fibrosis through the increase in TβRII, the…
View article
Cystic echinococcosis in South America: a call for action Open
Cystic echinococcosis (CE) or hydatidosis, a parasitic zoonosis caused by a cestode of the family Taeniidae, species Echinococcus granulosus, is endemic in Argentina, Chile, Peru, Uruguay, and southern Brazil. This report presents CE figur…
View article
Albendazole increases the inflammatory response and the amount of Em2-positive small particles of Echinococcus multilocularis (spems) in human hepatic alveolar echinococcosis lesions Open
Alveolar echinococcosis (AE) is a life-threatening disease in humans caused by the larval stages of E. multilocularis. It has been shown that the infection in humans is associated with a modulated immune response. Depending on multiple fac…