Chlamydia trachomatis
View article: Prevalence and Associated Risk Factors of Chlamydia trachomatis Infection: A Cross-sectional Study among Biology Students at the University of Lomé
Prevalence and Associated Risk Factors of Chlamydia trachomatis Infection: A Cross-sectional Study among Biology Students at the University of Lomé Open
Background: Chlamydia trachomatis (CT) is the most common bacterial sexually transmitted infection (STI) globally, particularly among young adults. In Togo, epidemiological data on CT prevalence in university settings are scarce. This stud…
View article: Epidemiological characteristics of Ureaplasma urealyticum, Chlamydia trachomatis, Neisseria gonorrhoeae, and herpes simplex virus among 5,577 gynecological outpatients in the Xihu district of Hangzhou, China
Epidemiological characteristics of Ureaplasma urealyticum, Chlamydia trachomatis, Neisseria gonorrhoeae, and herpes simplex virus among 5,577 gynecological outpatients in the Xihu district of Hangzhou, China Open
This study characterizes the epidemiology of UU, CT, NG, and HSV in real-world obstetrics and gynecology outpatient settings in Xihu District, Hangzhou. Given the elevated positivity among younger women, targeted health education and manag…
View article: Association Between Maternal Chlamydia Infection and Gestational Age at Delivery- A Time-to-Event Analysis
Association Between Maternal Chlamydia Infection and Gestational Age at Delivery- A Time-to-Event Analysis Open
Background Preterm birth is a leading cause of neonatal morbidity and mortality worldwide. Maternal infections, including Chlamydia trachomatis, have been linked to adverse pregnancy outcomes, yet their influence on the timing of delivery …
View article: Comparative transcriptomic profiling of human conjunctival epithelial cells and macrophages in response to Chlamydia trachomatis genovars A and B in early- and mid-infection cycles
Comparative transcriptomic profiling of human conjunctival epithelial cells and macrophages in response to Chlamydia trachomatis genovars A and B in early- and mid-infection cycles Open
Chlamydia trachomatis (Ct), an obligate intracellular bacterium, is the primary infectious cause of blindness through trachoma. Ct undergoes a unique biphasic developmental cycle between infectious elementary bodies and replicating reticul…
View article: Prevalence of genital and anorectal chlamydia trachomatis in Kenya by risk groups: a systematic review and meta-analysis
Prevalence of genital and anorectal chlamydia trachomatis in Kenya by risk groups: a systematic review and meta-analysis Open
The epidemiology of Chlamydia trachomatis (CT) in Kenya is not well understood. We conducted a systematic review and meta-analysis of CT prevalence using PubMed, Embase, and Kenyan databases (Jan 2000-June 2024). Included studies had labor…
View article: Chlamydia and pregnancy: Features of the course and therapy
Chlamydia and pregnancy: Features of the course and therapy Open
Chlamydia infection is one of the most common sexually transmitted infections. It is caused by the obligate intracellular bacterium Chlamydia trachomatis, which affects both men and women, but in most cases it is asymptomatic, making timel…
View article: Strengthening chlamydia management in Australian general practice using interventions that align with the clinic workflow: implementation and feasibility trial findings
Strengthening chlamydia management in Australian general practice using interventions that align with the clinic workflow: implementation and feasibility trial findings Open
Objective To evaluate the implementation and impact of the Management of Chlamydia Cases in Australia (MoCCA) intervention for strengthening chlamydia management in Australian general practice. Design Non-randomised implementation and feas…
View article: Primary prevention of Chlamydia trachomatis infection in young women: impact of an informational video in a Swiss gynaecology emergency department
Primary prevention of Chlamydia trachomatis infection in young women: impact of an informational video in a Swiss gynaecology emergency department Open
OBJECTIVES: The primary objective was to measure the impact of passive exposure to an educational video about Chlamydia trachomatis infection shown in a gynaecology department waiting room on young women’s knowledge on the subject. The sec…
View article: Invariant and Diverse NKT Cells Regulate Bacterial Clearance and Pathology in Chlamydial Genital Tract Infection in Mice
Invariant and Diverse NKT Cells Regulate Bacterial Clearance and Pathology in Chlamydial Genital Tract Infection in Mice Open
Chlamydia trachomatis infection causes pelvic inflammatory disease and infertility, but how host immune factors control pathogen clearance or pathology is not fully understood. Using a mouse model of genital tract infection with Chlamydia …
View article: Prevalence of Ureaplasma urealyticum, Chlamydia trachomatis, Neisseria gonorrhoeae and Herpes simplex virus in Hangzhou, China
Prevalence of Ureaplasma urealyticum, Chlamydia trachomatis, Neisseria gonorrhoeae and Herpes simplex virus in Hangzhou, China Open
View article: Chlamydia trachomatis highjacks host MYO1C for actin cage recruitment at the bacterial inclusion
Chlamydia trachomatis highjacks host MYO1C for actin cage recruitment at the bacterial inclusion Open
Chlamydia trachomatis (Ct), a Gram-negative obligate intracellular pathogen, manipulates host actin dynamics to facilitate its entry, development, and exit. It assembles a dynamic actin cage around its intracellular niche, known as the 'in…
View article: Prevalence of <i>Neisseria meningitidis</i> in urine from men in Ohio by molecular testing
Prevalence of <i>Neisseria meningitidis</i> in urine from men in Ohio by molecular testing Open
Background Meningococcal urethritis is recognized as an emerging disease. However, its contemporary prevalence is unknown, and no molecular diagnostic tests are commercially available. With the widespread transition to molecular methods fo…
View article: Prevalence of <i>Clamydia trachomatis</i> colonization amongst asymptomatic pregnant women in Eket and its environs, Akwa Ibom State, Nigeria
Prevalence of <i>Clamydia trachomatis</i> colonization amongst asymptomatic pregnant women in Eket and its environs, Akwa Ibom State, Nigeria Open
Chlamydia trachomatis is one of the most common causes of STDs. It is also known to be an asymptomatic coloniser in women. During pregnancy and delivery, vertical transmission of these bacteria can result in conjunctivitis and pneumonia in…
View article: Chlamydia trachomatis Infection and Its Association with Human Papillomavirus Among Adolescent Girls and Young Women of Eastern Cape, South Africa
Chlamydia trachomatis Infection and Its Association with Human Papillomavirus Among Adolescent Girls and Young Women of Eastern Cape, South Africa Open
Background/Objectives: Adolescent girls and young women (AGYW) have a high burden of sexually transmitted infections (STIs). This study examined the prevalence of Chlamydia trachomatis, its association with human papillomavirus (HPV), and …
View article: Клинический случай неуспеха терапии персистирующей микоплазменной инфекции, обусловленной Mycoplasma genitalium, с выявленной лекарственной устойчивостью к макролидам и фторхинолонам
Клинический случай неуспеха терапии персистирующей микоплазменной инфекции, обусловленной Mycoplasma genitalium, с выявленной лекарственной устойчивостью к макролидам и фторхинолонам Open
Mycoplasma genitalium является патогеном, принадлежащим к группе возбудителей инфекций, передаваемых половым путем. Клиническая картина микоплазменной инфекции не имеет специфических симптомов и сопровождается такими заболеваниями, как уре…
View article: Prevalence of Chlamydia trachomatis, Ureaplasma spp., Mycoplasma hominis and Mycoplasma genitalium in patients with sterile pyuria
Prevalence of Chlamydia trachomatis, Ureaplasma spp., Mycoplasma hominis and Mycoplasma genitalium in patients with sterile pyuria Open
View article: RELATIONSHIP BETWEEN REACTIVE OXYGEN SPECIES, VITAMIN E, CATALASE AND CHLAMYDIA TRACHOMATIS IN SERUM OF INFERTILE FEMALE
RELATIONSHIP BETWEEN REACTIVE OXYGEN SPECIES, VITAMIN E, CATALASE AND CHLAMYDIA TRACHOMATIS IN SERUM OF INFERTILE FEMALE Open
Background: The failure in female reproductive system could be cause infertility according to different factors such as sperm isoantobody, zona pellucid antibody, ovarian antibody, Chlamydia trachomatis infection,…
View article: The roles of TGFb signaling in CD4 T cell responses to Chlamydia infection in the female reproductive tract 9284
The roles of TGFb signaling in CD4 T cell responses to Chlamydia infection in the female reproductive tract 9284 Open
Description CD4 T cells are essential for host immunity to the intracellular bacterium Chlamydia, and the formation of tissue-resident memory CD4 T cells (CD4 TRM) in the female reproductive tract (FRT) is key for vaccine-induced protectiv…
View article: Insights into chlamydial infection at the sub-cellular level using label-free Raman spectroscopy in comparison to electron microscopy
Insights into chlamydial infection at the sub-cellular level using label-free Raman spectroscopy in comparison to electron microscopy Open
Intracellular infections are difficult to study as the host cell protects the pathogen from direct observation from the outside. Transmission electron microscopy (TEM) is the most commonly used method for subcellular analysis. However, sam…
View article: Evaluation of Mycoplasma genitalium positivity and co-infection with Chlamydia trachomatis and/or Neisseria gonorrhoeae at various care sites across the United States
Evaluation of Mycoplasma genitalium positivity and co-infection with Chlamydia trachomatis and/or Neisseria gonorrhoeae at various care sites across the United States Open
MG positivity was high and MG co-infection with CT was common. These findings improve understanding of MG prevalence and may help inform the targeting of MG screening to specific patient populations. Co-infection data support using multipl…
View article: The impact of dynamic mucosal baseline immune states on C. muridarum and N. gonorrhoeae infection outcomes in a murine menstruation model 3775
The impact of dynamic mucosal baseline immune states on C. muridarum and N. gonorrhoeae infection outcomes in a murine menstruation model 3775 Open
Description Although the menstrual cycle influences the risk of acquiring sexually transmitted infections (STIs), the underlying immune contributions are poorly defined. A mouse model simulating the immune-mediated process of endometrial r…
View article: RELATIONSHIP BETWEEN REACTIVE OXYGEN SPECIES, VITAMIN E, CATALASE AND CHLAMYDIA TRACHOMATIS IN SERUM OF INFERTILE FEMALE
RELATIONSHIP BETWEEN REACTIVE OXYGEN SPECIES, VITAMIN E, CATALASE AND CHLAMYDIA TRACHOMATIS IN SERUM OF INFERTILE FEMALE Open
Background: The failure in female reproductive system could be cause infertility according to different factors such as sperm isoantobody, zona pellucid antibody, ovarian antibody, Chlamydia trachomatis infection, hormonal imbalance and ev…
View article: Sexual behaviours and sexually transmitted infections among MSM living with HIV followed at a university hospital in Istanbul, Turkey
Sexual behaviours and sexually transmitted infections among MSM living with HIV followed at a university hospital in Istanbul, Turkey Open
Background Men sex with men (MSM) are accepted as a hidden key population in the dissemination of HIV in Turkey. Understanding sexual behaviours and Sexually Transmitted Infections (STI) frequency in MSM living with HIV is important to pro…
View article: Prevalence of Sexually Transmitted Infections (Syphilis, N. Gonorrhea, and Chlamydia) in Odisha and Andhra Pradesh: A Systematic Review and Meta-analysis
Prevalence of Sexually Transmitted Infections (Syphilis, N. Gonorrhea, and Chlamydia) in Odisha and Andhra Pradesh: A Systematic Review and Meta-analysis Open
Background: Sexually transmitted infections (STIs) are a major global public health concern and are linked with human immunodeficiency virus in many ways. There is little evidence of the pooled prevalence of STIs across both states (Andhra…
View article: Clinical Validation of Loop‐Mediated Isothermal Amplification Assays for the Rapid Detection of <i>Neisseria gonorrhoeae</i> and <i>Chlamydia trachomatis</i>
Clinical Validation of Loop‐Mediated Isothermal Amplification Assays for the Rapid Detection of <i>Neisseria gonorrhoeae</i> and <i>Chlamydia trachomatis</i> Open
Neisseria gonorrhoeae (GC) and Chlamydia trachomatis (CT) are the predominant causes of bacterial sexually transmitted diseases. While nucleic acid amplification testing (NAATs), primarily polymerase chain reaction (PCR), is regarded as th…
View article: Author response: The second messenger signaling molecule cyclic di-AMP drives developmental cycle progression in Chlamydia trachomatis
Author response: The second messenger signaling molecule cyclic di-AMP drives developmental cycle progression in Chlamydia trachomatis Open
View article: Reviewer #2 (Public review): The second messenger signaling molecule cyclic di-AMP drives developmental cycle progression in Chlamydia trachomatis
Reviewer #2 (Public review): The second messenger signaling molecule cyclic di-AMP drives developmental cycle progression in Chlamydia trachomatis Open
View article: eLife Assessment: The second messenger signaling molecule cyclic di-AMP drives developmental cycle progression in Chlamydia trachomatis
eLife Assessment: The second messenger signaling molecule cyclic di-AMP drives developmental cycle progression in Chlamydia trachomatis Open
View article: The second messenger signaling molecule cyclic di-AMP drives developmental cycle progression in Chlamydia trachomatis
The second messenger signaling molecule cyclic di-AMP drives developmental cycle progression in Chlamydia trachomatis Open
The obligate intracellular bacterium Chlamydia alternates between two functional forms during its developmental cycle: elementary body (EB) and reticulate body (RB). However, the molecular mechanisms governing the transitions between these…
View article: Unveiling Chlamydia trachomatis immunity in urogenital secretions: A systematic review
Unveiling Chlamydia trachomatis immunity in urogenital secretions: A systematic review Open
Chlamydia trachomatis (CT) is a highly prevalent bacterial sexually transmitted infection (STI), associated with severe disease complications. CT targets a unique immunological environment: the genital tract epithelium. Although sam…