Erythrocyte sedimentation rate
View article: Correlation of TSH Levels with Inflammatory Markers in COVID-19 Patients: A Retrospective Study
Correlation of TSH Levels with Inflammatory Markers in COVID-19 Patients: A Retrospective Study Open
Background: COVID-19 caused by SARS-CoV-2 is an acute disease which may lead to severe systemic inflammation, causing multi-organ dysfunction and death. Studies indicated that thyroid-stimulating hormone (TSH) levels were lower when the in…
View article: The prognostic value of Neutrophil-Lymphocyte ratio as an early predictor of clinical outcomes in acute Cholangitis
The prognostic value of Neutrophil-Lymphocyte ratio as an early predictor of clinical outcomes in acute Cholangitis Open
Background Acute cholangitis is a life-threatening biliary infection associated with substantial morbidity and mortality if not promptly managed. Early identification of high-risk patients is crucial for improved outcomes. The neutrophil–l…
View article: A comparative study of serum homocysteine levels among chronic obstructive pulmonary disease patients with and without acute exacerbation
A comparative study of serum homocysteine levels among chronic obstructive pulmonary disease patients with and without acute exacerbation Open
Objectives: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. Acute exacerbations of COPD significantly impact disease progression and patient outcomes. Serum homocysteine, a potential bi…
View article: Development and validation of a clinical prediction model for in-hospital mortality of severe pneumonia based on machine learning
Development and validation of a clinical prediction model for in-hospital mortality of severe pneumonia based on machine learning Open
Objective We aimed to develop an interpretable model to predict the mortality risk for severe pneumonia patients. Methods The study retrospectively employed data from severe pneumonia patients at two hospitals as the training set for the m…
View article: High Prevalence and Clinical Associations of Vitamin D Deficiency in Inflammatory Bowel Disease: Evidence from a Tertiary Center Cohort
High Prevalence and Clinical Associations of Vitamin D Deficiency in Inflammatory Bowel Disease: Evidence from a Tertiary Center Cohort Open
Background/Objectives: Vitamin D in its active form, 1,25-dihydroxyvitamin D3 [1,25(OH)2D3], plays a critical role in immune regulation, gut barrier function, and systemic inflammation. Its deficiency is frequent in Inflammatory Bowel Dise…
View article: Associations of novel blood-derived markers of inflammation with blood pressure, arterial stiffness and heart rate in young adults
Associations of novel blood-derived markers of inflammation with blood pressure, arterial stiffness and heart rate in young adults Open
Background Although C-reactive protein (CRP) is often used to assess inflammation and can predict high blood pressure (BP) and arterial stiffness, novel measures of inflammation derived from platelets, white blood cell counts, and high-den…
View article: Chronic inflammatory arthritis in 22q11.2 deletion (DiGeorge) syndrome: a multicentric study
Chronic inflammatory arthritis in 22q11.2 deletion (DiGeorge) syndrome: a multicentric study Open
Background 22q11 deletion syndrome (22q11DS) is a genetic disorder caused by a deletion at chromosome 22q11.2. Chronic arthritis may be occasionally observed in these, if this manifestion represents a concomitant association of two disease…
View article: Diagnostic value of blood count derived inflammatory biomarkers in differentiating occult psoriatic arthritis from psoriasis
Diagnostic value of blood count derived inflammatory biomarkers in differentiating occult psoriatic arthritis from psoriasis Open
Background Psoriatic arthritis (PsA) is a long-term immune mediated condition. That can develop in individuals with psoriasis, often before any obvious symptoms appear. These asymptomatic individuals, classified as having occult PsA, may a…
View article: Pulmonary lesion volume ratio and laboratory parameters as risk factors for plastic bronchitis in pediatric refractory Mycoplasma pneumoniae pneumonia
Pulmonary lesion volume ratio and laboratory parameters as risk factors for plastic bronchitis in pediatric refractory Mycoplasma pneumoniae pneumonia Open
Background Refractory Mycoplasma pneumoniae pneumonia (RMPP) frequently leads to complications, including plastic bronchitis (PB). This study aimed to identify clinical risk factors for PB development in pediatric RMPP. Methods A total of …
View article: Efficacy and safety of tacrolimus in the treatment of interstitial pneumonia with autoimmune features: a retrospective study
Efficacy and safety of tacrolimus in the treatment of interstitial pneumonia with autoimmune features: a retrospective study Open
Objective To evaluate the efficacy and safety of tacrolimus in interstitial pneumonia with autoimmune features (IPAF). Methods 48 IPAF patients receiving tacrolimus were retrospectively analyzed. Changes in high-resolution computed tomogra…
View article: Cytopenias in Compensated Versus Decompensated Liver Function: Is There a Difference?
Cytopenias in Compensated Versus Decompensated Liver Function: Is There a Difference? Open
Background/Objectives: Patients with liver cirrhosis (LC) present hematological abnormalities with multiple etiologies. As liver function deteriorates, these abnormalities become more evident, conferring a higher risk of morbidity and mort…
View article: Comparison of the Wintrobe Method with the Westergren Method for the Estimation of Erythrocyte Sedimentation Rate (ESR)
Comparison of the Wintrobe Method with the Westergren Method for the Estimation of Erythrocyte Sedimentation Rate (ESR) Open
Background: Erythrocyte Sedimentation Rate (ESR) is a widely used hematological test for detecting inflammation and monitoring disease progression. Among the various methods for ESR determination, the Wintrobe and Westergren methods are co…
View article: Research advances of pan-immune inflammation value in rheumatoid arthritis
Research advances of pan-immune inflammation value in rheumatoid arthritis Open
Rheumatoid arthritis (RA) is a persistent autoimmune condition marked by systemic inflammation, primarily impacting multiple joints and causing irreversible structural and functional damage. While pathophysiology remains complex, immune ce…
View article: Evaluation of Human Brucellosis Patients with Post-Treatment Standard Tube Agglutination Test Titers
Evaluation of Human Brucellosis Patients with Post-Treatment Standard Tube Agglutination Test Titers Open
Introduction: This study was designed to determine the differences between brucellosis patients whose standard tube agglutination test (SAT) titers decreased or not after successful treatment. Methods: This retrospective study included pat…
View article: The potential value of fibrinogen-to-albumin ratio in assessing disease activity in rheumatoid arthritis
The potential value of fibrinogen-to-albumin ratio in assessing disease activity in rheumatoid arthritis Open
Background The fibrinogen-to-albumin ratio (FAR) has emerged as a promising inflammatory marker, but its relationship with rheumatoid arthritis (RA) disease activity remains unclear. This study sought to elucidate the association between F…
View article: Quantitative Bone SPECT/CT in Diabetic Foot Osteomyelitis: Diagnostic Performance Within-Patient Lesion–Contralateral Separation and Associations with Inflammatory Burden
Quantitative Bone SPECT/CT in Diabetic Foot Osteomyelitis: Diagnostic Performance Within-Patient Lesion–Contralateral Separation and Associations with Inflammatory Burden Open
Objective: We sought to assess the diagnostic performance of quantitative bone SPECT/CT standardized uptake values (SUVs) in diabetic foot osteomyelitis (DFO) and their associations with inflammatory biomarkers. Methods: We retrospectively…
View article: Implementation of Anti-Bip Antibodies as A Novel Biomarker in The Diagnosis of Rheumatoid Arthritis
Implementation of Anti-Bip Antibodies as A Novel Biomarker in The Diagnosis of Rheumatoid Arthritis Open
Background: Anti-BiP antibodies, directed against the binding immunoglobulin protein (BiP), have recently been identified as potential biomarkers in autoimmune diseases such as rheumatoid arthritis (RA). They are involved in ER stress resp…
View article: Clinical Evaluation of the Combined Use of Basic Fibroblast Growth Factor and Light Therapy in Managing Peripherally Inserted Central Catheter-Associated Phlebitis in Leukemia Patients
Clinical Evaluation of the Combined Use of Basic Fibroblast Growth Factor and Light Therapy in Managing Peripherally Inserted Central Catheter-Associated Phlebitis in Leukemia Patients Open
Background: The primary objective was to assess the effectiveness and safety of combined bFGF and light therapy for Peripherally Inserted Central Catheters (PICC) phlebitis, measuring improvements in phlebitis grading and Visual Analogue S…
View article: Cross-sectional study of the relationship between dietary inflammatory index and inflammatory hormonal and metabolic profiles in polycystic ovary syndrome
Cross-sectional study of the relationship between dietary inflammatory index and inflammatory hormonal and metabolic profiles in polycystic ovary syndrome Open
Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder characterized by obesity, hyperandrogenism, and dyslipidemia, with chronic inflammation playing a key role in its pathogenesis. While the Dietary Inflammatory Index (DII) h…
View article: Morphological features of synovial membrane in traumatic knee injuries in patients with metabolic disorders
Morphological features of synovial membrane in traumatic knee injuries in patients with metabolic disorders Open
Background. Traumatic knee injuries in patients with metabolic comorbidities present a clinical challenge due to altered healing processes and inflammatory responses. The synovial membrane plays a crucial role in post-traumatic inflammatio…
View article: Curcumin Benefits in Children with Active Lupus Nephritis via NLRP3 Inflammasome Inhibition‐ A Randomized Controlled Trial
Curcumin Benefits in Children with Active Lupus Nephritis via NLRP3 Inflammasome Inhibition‐ A Randomized Controlled Trial Open
Lupus nephritis is a serious complication of childhood systemic lupus erythematous (cSLE). Nucleotide‐binding domain, leucine‐rich–containing family, pyrin domain–containing‐3 (NLRP3) inflammasome activation is one of the pathogenic pathwa…
View article: COVID-19 and Autoimmunity: Unravelling the GAD65 Connection in Non-diabetic Patients
COVID-19 and Autoimmunity: Unravelling the GAD65 Connection in Non-diabetic Patients Open
Introduction: The Coronavirus Disease-2019 (COVID-19) pandemic has raised significant concerns regarding its longterm health impacts, particularly among individuals without preexisting conditions. Emerging evidence suggests a potential lin…
View article: THE INFLUENCE OF BLOOD VOLUME AND STORAGE DURATION ON THE ERYTHROCYTE SEDIMENTATION RATE (ESR) VALUE USING THE WESTERGREN METHOD
THE INFLUENCE OF BLOOD VOLUME AND STORAGE DURATION ON THE ERYTHROCYTE SEDIMENTATION RATE (ESR) VALUE USING THE WESTERGREN METHOD Open
Background: Hematological examination is conducted to determine the condition of blood and its components, which are used to establish a diagnosis, support a diagnosis, make a differential diagnosis, monitor disease progression, assess the…
View article: Effect of Iodine-Impregnated Plastic Adhesive Drapes in Preventing Surgical Site Infection Post Spine Surgeries
Effect of Iodine-Impregnated Plastic Adhesive Drapes in Preventing Surgical Site Infection Post Spine Surgeries Open
BackgroundSurgical site infections (SSIs) represent a significant source of complications following spine surgeries. In this study, iodine-impregnated plastic adhesive drapes (PAD) are explored as a means to mitigate contamination and infe…
View article: IL-17A and IL-6 as Key Mediators of Immune Dysregulation and Systemic Inflammation in Psoriasis
IL-17A and IL-6 as Key Mediators of Immune Dysregulation and Systemic Inflammation in Psoriasis Open
The psoriasis, which is a chronic inflammatory skin disease, in addition is immune-mediated, is also characterized by hyperproliferation of keratinocytes and infiltration of activated immune cells. Besides, psoriatic inflammation pathogene…
View article: Anti-inflammatory efficacy of Mangifera indica stem-bark, carica papaya and eucalyptus leaf extracts on formalin-induced inflammation in rats
Anti-inflammatory efficacy of Mangifera indica stem-bark, carica papaya and eucalyptus leaf extracts on formalin-induced inflammation in rats Open
Inflammation is part of the body's defense mechanism and can be acute or chronic. Inflammatory disease prevalence is on the increase in Africa and anti-inflammatory efficacious alternatives are continually sought for. Effects of herbal rem…
View article: Assessment of serum diagnostic biomarkers for periprosthetic joint infection in hip and knee arthroplasty: a retrospective study
Assessment of serum diagnostic biomarkers for periprosthetic joint infection in hip and knee arthroplasty: a retrospective study Open
Background Periprosthetic joint infection (PJI) after total hip and knee arthroplasty is challenging to differentiate from similar afflictions. Platelet count-to-mean platelet volume (PC/MPV) ratio has been proposed, but requires validatio…
View article: Exploring the Relationship Between Diet and Rheumatoid Arthritis – A Review of the Literature
Exploring the Relationship Between Diet and Rheumatoid Arthritis – A Review of the Literature Open
Background: Rheumatoid arthritis (RA) is a chronic inflammatory condition affecting joints. It is managed with pharmacological therapies, but it is speculated that dietary intervention may be of significant benefit to patients in helping t…
View article: Clinical prediction model for the risk of bleeding during hospitalization in patients with acute myocardial infarction: a retrospective cohort study from the MIMIC-IV database
Clinical prediction model for the risk of bleeding during hospitalization in patients with acute myocardial infarction: a retrospective cohort study from the MIMIC-IV database Open
Background Bleeding is a serious and potentially life-threatening complication in patients with acute myocardial infarction (AMI), significantly affecting patient outcomes. Early identification of high-risk patients is critical for reducin…
View article: Rare Case of Hemoglobin Lepore Trait in a Bangladeshi Patient with Polyarthritis and Fever: Case Description and Brief Literature Review
Rare Case of Hemoglobin Lepore Trait in a Bangladeshi Patient with Polyarthritis and Fever: Case Description and Brief Literature Review Open
Introduction: In hemoglobinopathies, the amount of globin synthesis in hemoglobin (Hb) or its structure is altered. Clinical features are related to the rate and kind of structural aberrations. The heterozygous form of the Lepore syndrome …