Ovary
View article: TARGETING TYPE-I PRMTS RESTORES PLATINUM SENSITIVITY IN OVARIAN CARCINOMA THROUGH MITOCHONDRIAL METABOLISM
TARGETING TYPE-I PRMTS RESTORES PLATINUM SENSITIVITY IN OVARIAN CARCINOMA THROUGH MITOCHONDRIAL METABOLISM Open
View article: Metformin prevents oxidative stress and apoptosis of ovarian granulosa cells in polycystic ovary syndrome via activation of Nrf2-HO-1 pathway.
Metformin prevents oxidative stress and apoptosis of ovarian granulosa cells in polycystic ovary syndrome via activation of Nrf2-HO-1 pathway. Open
The findings of the study suggest that metformin protects ovarian granulosa cells against oxidative stress and apoptosis in the context of PCOS via activation of Nrf2-HO-1 pathway.
View article: Supplementary Figure 2 from TWEAK–Fn14–RelB Signaling Cascade Promotes Stem Cell–like Features that Contribute to Post-Chemotherapy Ovarian Cancer Relapse
Supplementary Figure 2 from TWEAK–Fn14–RelB Signaling Cascade Promotes Stem Cell–like Features that Contribute to Post-Chemotherapy Ovarian Cancer Relapse Open
TWEAK has minimal effect on proliferation or apoptosis of ovarian cancer cells
View article: Supplementary Figure 8 from Continuous Administration of Anti-VEGFA Antibody Upregulates PAI-1 Secretion from Ovarian Cancer Cells via miR-143-3p Downregulation
Supplementary Figure 8 from Continuous Administration of Anti-VEGFA Antibody Upregulates PAI-1 Secretion from Ovarian Cancer Cells via miR-143-3p Downregulation Open
Supplementary Figure 8 shows the representative images of immunohistochemical staining of a human normal kidney for PAI-1 and CD31.
View article: Table S2 from HCK Promotes High-Grade Serous Ovarian Cancer Tumorigenesis through CD44 and NOTCH3 Signaling
Table S2 from HCK Promotes High-Grade Serous Ovarian Cancer Tumorigenesis through CD44 and NOTCH3 Signaling Open
CAOV3 RPPA data summary
View article: Figure S2 from Bepotastine Sensitizes Ovarian Cancer to PARP Inhibitors through Suppressing NF-κB–Triggered SASP in Cancer-Associated Fibroblasts
Figure S2 from Bepotastine Sensitizes Ovarian Cancer to PARP Inhibitors through Suppressing NF-κB–Triggered SASP in Cancer-Associated Fibroblasts Open
Figure S2, related to Fig 2
View article: Fig S1 from HCK Promotes High-Grade Serous Ovarian Cancer Tumorigenesis through CD44 and NOTCH3 Signaling
Fig S1 from HCK Promotes High-Grade Serous Ovarian Cancer Tumorigenesis through CD44 and NOTCH3 Signaling Open
Distribution of clinical features associated with poor and good prognostic HGSOC patient samples in the TCGA U133A dataset.
View article: Fig S2 from HCK Promotes High-Grade Serous Ovarian Cancer Tumorigenesis through CD44 and NOTCH3 Signaling
Fig S2 from HCK Promotes High-Grade Serous Ovarian Cancer Tumorigenesis through CD44 and NOTCH3 Signaling Open
The source of elevated HCK signature is not due to a bias in tumor purity or immune infiltration.
View article: Supplementary Tables 1 - 5. Supplementary Figures 1 - 3 from COMMD3-Mediated Endosomal Trafficking of HER2 Inhibits the Progression of Ovarian Carcinoma
Supplementary Tables 1 - 5. Supplementary Figures 1 - 3 from COMMD3-Mediated Endosomal Trafficking of HER2 Inhibits the Progression of Ovarian Carcinoma Open
Table S1. Differential receptor proteins detected by mass spectrometry Table S2. Antibodies used in this study Table S3. RT-qPCR primers Table S4. shRNA Table S5. The top 20 candidate genes screened by MAGeCK analysis algorithm Figure S1. …
View article: Fig S4 from HCK Promotes High-Grade Serous Ovarian Cancer Tumorigenesis through CD44 and NOTCH3 Signaling
Fig S4 from HCK Promotes High-Grade Serous Ovarian Cancer Tumorigenesis through CD44 and NOTCH3 Signaling Open
The effect of GSIs on NOTCH3 ICD expression in HGSOC cells following HCK overexpression.
View article: Table S1 from Comparative Tumor Microenvironment Analysis of Primary and Recurrent Ovarian Granulosa Cell Tumors
Table S1 from Comparative Tumor Microenvironment Analysis of Primary and Recurrent Ovarian Granulosa Cell Tumors Open
RNA Sequencing QC Metrics
View article: Table S1 from HCK Promotes High-Grade Serous Ovarian Cancer Tumorigenesis through CD44 and NOTCH3 Signaling
Table S1 from HCK Promotes High-Grade Serous Ovarian Cancer Tumorigenesis through CD44 and NOTCH3 Signaling Open
Summary of the IHC staining of HCK in ovarian cancer tissue microarrays.
View article: Figure S3 from Bepotastine Sensitizes Ovarian Cancer to PARP Inhibitors through Suppressing NF-κB–Triggered SASP in Cancer-Associated Fibroblasts
Figure S3 from Bepotastine Sensitizes Ovarian Cancer to PARP Inhibitors through Suppressing NF-κB–Triggered SASP in Cancer-Associated Fibroblasts Open
Figure S3, related to Fig 4
View article: Supplementary Figure legends from Bepotastine Sensitizes Ovarian Cancer to PARP Inhibitors through Suppressing NF-κB–Triggered SASP in Cancer-Associated Fibroblasts
Supplementary Figure legends from Bepotastine Sensitizes Ovarian Cancer to PARP Inhibitors through Suppressing NF-κB–Triggered SASP in Cancer-Associated Fibroblasts Open
Supplementary Figure legends
View article: Table S1-S6 from Bepotastine Sensitizes Ovarian Cancer to PARP Inhibitors through Suppressing NF-κB–Triggered SASP in Cancer-Associated Fibroblasts
Table S1-S6 from Bepotastine Sensitizes Ovarian Cancer to PARP Inhibitors through Suppressing NF-κB–Triggered SASP in Cancer-Associated Fibroblasts Open
Supplementary table
View article: Table S3 from Comparative Tumor Microenvironment Analysis of Primary and Recurrent Ovarian Granulosa Cell Tumors
Table S3 from Comparative Tumor Microenvironment Analysis of Primary and Recurrent Ovarian Granulosa Cell Tumors Open
Differentially Expressed Genes
View article: Table S2 from Comparative Tumor Microenvironment Analysis of Primary and Recurrent Ovarian Granulosa Cell Tumors
Table S2 from Comparative Tumor Microenvironment Analysis of Primary and Recurrent Ovarian Granulosa Cell Tumors Open
Clinical Characteristics by Patient
View article: Figure S1 from Bepotastine Sensitizes Ovarian Cancer to PARP Inhibitors through Suppressing NF-κB–Triggered SASP in Cancer-Associated Fibroblasts
Figure S1 from Bepotastine Sensitizes Ovarian Cancer to PARP Inhibitors through Suppressing NF-κB–Triggered SASP in Cancer-Associated Fibroblasts Open
Figure S1, related to Fig 1
View article: Fig S3 from HCK Promotes High-Grade Serous Ovarian Cancer Tumorigenesis through CD44 and NOTCH3 Signaling
Fig S3 from HCK Promotes High-Grade Serous Ovarian Cancer Tumorigenesis through CD44 and NOTCH3 Signaling Open
Cell line selection and engineering
View article: Figure S4 from Bepotastine Sensitizes Ovarian Cancer to PARP Inhibitors through Suppressing NF-κB–Triggered SASP in Cancer-Associated Fibroblasts
Figure S4 from Bepotastine Sensitizes Ovarian Cancer to PARP Inhibitors through Suppressing NF-κB–Triggered SASP in Cancer-Associated Fibroblasts Open
Figure S4, related to Fig 6
View article: Supplementary Table 1 from Associations of Dietary Patterns with Colorectal Adenomas in the Prostate, Lung, Colorectal, and Ovarian Cancer Cohort
Supplementary Table 1 from Associations of Dietary Patterns with Colorectal Adenomas in the Prostate, Lung, Colorectal, and Ovarian Cancer Cohort Open
Supplementary table 1 contains results for subgroup analysis by BMI and age group
View article: Polymorphisms of METTL3 gene and ovarian cancer susceptibility: A three‑center case‑control study
Polymorphisms of METTL3 gene and ovarian cancer susceptibility: A three‑center case‑control study Open
View article: Supplementary Figure 2 from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium
Supplementary Figure 2 from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium Open
Supplementary Figure 2 shows two forest plots depicting the association between (A) dietary folate intake and (B) supplemental folate intake and ovarian cancer for women with endometriosis, stratified by potential effect modifiers
View article: Supplemental Table 3 from Germline Mutations in 12 Genes and Risk of Ovarian Cancer in Three Population-Based Cohorts
Supplemental Table 3 from Germline Mutations in 12 Genes and Risk of Ovarian Cancer in Three Population-Based Cohorts Open
Supplemental Table 3: Mutation frequencies in invasive ovarian cancer cases and controls and risk of ovarian cancer in the NHS, NHSII, and CPSII
View article: Trophoblast cell surface antigen 2 (TROP2) from ascitic extracellular vesicles drives peritoneal metastasis of ovarian cancer by mesothelial-to-mesenchymal transition
Trophoblast cell surface antigen 2 (TROP2) from ascitic extracellular vesicles drives peritoneal metastasis of ovarian cancer by mesothelial-to-mesenchymal transition Open
This study is the first to identify the pivotal role of TROP2 from ascitic EV in promoting metastatic dissemination by activating the TNF-α/NF-κB signaling axis. By remodeling the peritoneal microenvironment, TROP2 facilitates metastatic s…
View article: Supplemental Figure 1 from Measurement of Ovarian Tumor Immune Profiles by Multiplex Immunohistochemistry: Implications for Epidemiologic Studies
Supplemental Figure 1 from Measurement of Ovarian Tumor Immune Profiles by Multiplex Immunohistochemistry: Implications for Epidemiologic Studies Open
Supplemental Figure 1 provides representative images from the T cell panel for high-grade serous, endometrioid, clear cell, and mucinous tumors.
View article: Supplementary Table 1 from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium
Supplementary Table 1 from Folate Intake and Ovarian Cancer Risk among Women with Endometriosis: A Case–Control Study from the Ovarian Cancer Association Consortium Open
Supplementary Table 1 shows the range of folate intake included in each tertile, by OCAC study site.
View article: An updated look into reactive oxygen species and cyclophosphamide-induced ovarian damage
An updated look into reactive oxygen species and cyclophosphamide-induced ovarian damage Open
View article: Establishment of immortalized ovarian stromal cell lines using Sendai virus vectors: a platform for studying tumor–stroma interactions and carcinogenesis
Establishment of immortalized ovarian stromal cell lines using Sendai virus vectors: a platform for studying tumor–stroma interactions and carcinogenesis Open
We aimed to generate immortalized stromal cell lines from the ovarian and fallopian tube tissues of a single patient using Sendai virus (SeV) vectors and identify candidate stromal genes involved in ovarian carcinogenesis. Tissues were col…
View article: Supplementary Table from Tobacco Smoking and Survival Following a Diagnosis with Ovarian Cancer
Supplementary Table from Tobacco Smoking and Survival Following a Diagnosis with Ovarian Cancer Open
Supplementary Table from Tobacco Smoking and Survival Following a Diagnosis with Ovarian Cancer