Dermatomyositis
View article: PO:25:075 | Cancer occurence in patients with idiopathic inflammatory myopathies: new insights from the analysis of a monocentric cohort
PO:25:075 | Cancer occurence in patients with idiopathic inflammatory myopathies: new insights from the analysis of a monocentric cohort Open
Background. Idiopathic inflammatory myopathies (IIMs) are rare systemic autoimmune disorders, associated with an increased risk of cancer. Data from International Guideline for IIMs-Associated Cancer Screening identified the following cond…
View article: Prognostic Implications of Myositis‐Specific Autoantibodies on Mortality, Relapse, and Remission in Dermatomyositis Patients
Prognostic Implications of Myositis‐Specific Autoantibodies on Mortality, Relapse, and Remission in Dermatomyositis Patients Open
Objectives To explore the clinicopathological features and treatment prognosis including death, relapse and remission of dermatomyositis (DM) based on myositis‐specific autoantibody (MSAs) stratification. Methods Patients with DM come from…
View article: PO:25:081 | Atypical onset of anti-SAE-1 positive dermatomyositis: paraneoplastic flame hemorrhages in urothelial carcinoma
PO:25:081 | Atypical onset of anti-SAE-1 positive dermatomyositis: paraneoplastic flame hemorrhages in urothelial carcinoma Open
Background. Flame hemorrhages are a manifestation of infectious endocarditis, as well as autoimmune or neoplastic diseases. Anti-SAE-1 antibodies (small ubiquitin-like modifier-activating enzyme, against enzymes involved in gene transcript…
View article: PO:24:057 | Qualitative and quantitative analysis of nailfold videocapillaroscopy in patients with idiopathic inflammatory myopathies: focus on muscle histology
PO:24:057 | Qualitative and quantitative analysis of nailfold videocapillaroscopy in patients with idiopathic inflammatory myopathies: focus on muscle histology Open
Background. Idiopathic inflammatory myopathies (IIM) are a group of autoimmune diseases characterized by inflammation of the muscle with clinical manifestations such as skin rash, interstitial lung disease, heart involvement or arthritis. …
View article: Angioedema as a Presenting Feature of Systemic Lupus Erythematosus With Myositis and Vasculitis—Successfully Treated With Mycophenolate and Prednisolone
Angioedema as a Presenting Feature of Systemic Lupus Erythematosus With Myositis and Vasculitis—Successfully Treated With Mycophenolate and Prednisolone Open
Introduction Angioedema is a rare manifestation of systemic lupus erythematosus (SLE). Myositis and vasculitis are uncommon manifestations of SLE. The former being a harbinger and feature of the latter has not been reported. Method A case …
View article: PO:24:066 | Antibody profile in myositis and early risk of interstitial lung disease: clinical and laboratory correlations in patients with suspected rheumatologic disease
PO:24:066 | Antibody profile in myositis and early risk of interstitial lung disease: clinical and laboratory correlations in patients with suspected rheumatologic disease Open
Background. Interstitial lung disease (ILD) is a frequent comorbidity not only in idiopathic inflammatory myopathies (IIM) but also in other rheumatologic disorders such as Sjögren’s syndrome, systemic sclerosis, and rheumatoid arthritis. …
View article: PO:25:079 | Anifrolumab in refractory dermatomyositis: a case report
PO:25:079 | Anifrolumab in refractory dermatomyositis: a case report Open
Background. Dermatomyositis is a rare autoimmune disease characterized by multisystem involvement. Treatment can be challenging, particularly in refractory cases unresponsive to conventional therapies, for which standardized management pro…
View article: Neutrophil lymphocyte ratio as a marker of skin disease activity in older children with juvenile dermatomyositis
Neutrophil lymphocyte ratio as a marker of skin disease activity in older children with juvenile dermatomyositis Open
View article: Unusual Clinical Presentation of Dermatomyositis in a Young Male: A Case Report
Unusual Clinical Presentation of Dermatomyositis in a Young Male: A Case Report Open
Dermatomyositis (DM) is a rare idiopathic inflammatory myopathy characterised by distinctive dermatological manifestations and systemic involvement. This present case report involved a 25-year-old male was presented with throat pain, progr…
View article: Correction: A retrospective natural history study in adult and juvenile patients with incident dermatomyositis and polymyositis using real world data
Correction: A retrospective natural history study in adult and juvenile patients with incident dermatomyositis and polymyositis using real world data Open
View article: Intermittent Glucocorticoid Pulse Combined With Mycophenolate Mofetil in Juvenile Dermatomyositis
Intermittent Glucocorticoid Pulse Combined With Mycophenolate Mofetil in Juvenile Dermatomyositis Open
This cohort study reports the long-term clinical outcomes of the use of intermittent intravenous methylprednisolone pulse therapy combined with mycophenolate mofetil for patients with juvenile dermatomyositis.
View article: Antisynthetase-like dermatomyositis related to anti-pm/scl-75: Case report
Antisynthetase-like dermatomyositis related to anti-pm/scl-75: Case report Open
This article reports the case of a 29-year-old female patient who presented with a severe inflammatory myopathy related to anti-PM/ SCL75 antibodies, with an antisynthetase-like clinical presentation
View article: An Evaluation of the Real-World Effectiveness of Immunoglobulin Therapy in Chronic Inflammatory Demyelinating Polyneuropathy
An Evaluation of the Real-World Effectiveness of Immunoglobulin Therapy in Chronic Inflammatory Demyelinating Polyneuropathy Open
Our findings support the effectiveness of Ig therapy in CIDP. The benefits of Ig seen in clinical trials of maintained or improved disability scores appear to be reflected in the real world by less deterioration in assistive device use and…
View article: Combination therapy improves survival prognosis in anti-MDA5-antibody-positive dermatomyositis patients: a single-center retrospective study
Combination therapy improves survival prognosis in anti-MDA5-antibody-positive dermatomyositis patients: a single-center retrospective study Open
Background Anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis (MDA5+DM) is associated with poor prognosis and high mortality, presenting significant challenges for treating this intractable disease. This stud…
View article: Paraneoplastic Dermatomyositis Due to Gallbladder Carcinoma
Paraneoplastic Dermatomyositis Due to Gallbladder Carcinoma Open
View article: Integrated metabolomic profiling identifies citrate as novel diagnostic biomarker for Anti-MDA5-Positive dermatomyositis
Integrated metabolomic profiling identifies citrate as novel diagnostic biomarker for Anti-MDA5-Positive dermatomyositis Open
Our study underscores the pivotal role of DHEAS and citrate as promising diagnostic biomarkers of IIM and anti-MDA5 + DM, respectively, providing novel insights into the pathogenic mechanism and potential therapeutic targets.
View article: Necrotizing Autoimmune Myopathy With HMGCR Antibodies: An Uncommon Presentation of Autoimmune Myositis in a Middle-Aged Woman Without Known Malignancy, Connective Tissue Disorder, or Statin Therapy
Necrotizing Autoimmune Myopathy With HMGCR Antibodies: An Uncommon Presentation of Autoimmune Myositis in a Middle-Aged Woman Without Known Malignancy, Connective Tissue Disorder, or Statin Therapy Open
View article: COVID-19-Associated MDA5-Mediated Necrotizing Myositis
COVID-19-Associated MDA5-Mediated Necrotizing Myositis Open
View article: Baricitinib could improve the prognosis of anti-MDA5 antibody positive dermatomyositis associated interstitial lung disease
Baricitinib could improve the prognosis of anti-MDA5 antibody positive dermatomyositis associated interstitial lung disease Open
View article: Case Report: Telitacicept for interstitial lung disease associated with idiopathic inflammatory myopathies: an observational study
Case Report: Telitacicept for interstitial lung disease associated with idiopathic inflammatory myopathies: an observational study Open
Background Interstitial lung disease (ILD) is the most common complication and the major cause of mortality among patients with idiopathic inflammatory myopathies (IIMs). Currently, no recommended standard treatment for IIM-associated ILD.…
View article: Revisiting the link between oropharyngeal dysphagia and cancer in autoimmune myositis: a descriptive study
Revisiting the link between oropharyngeal dysphagia and cancer in autoimmune myositis: a descriptive study Open
View article: Clue to Diagnosis: Flagellate Erythema in Anti-MDA5 Antibody-Positive Dermatomyositis in a Patient with Skin of Color
Clue to Diagnosis: Flagellate Erythema in Anti-MDA5 Antibody-Positive Dermatomyositis in a Patient with Skin of Color Open
Anti–melanoma differentiation-associated gene 5 (MDA5) antibody-positive dermatomyositis (DM) is a rare subtype of clinically amyopathic DM characterized by minimal muscle involvement, variable skin manifestations, and a high risk of rapid…
View article: Case Report: Possible association between dermatomyositis and Trastuzumab Deruxtecan therapy of triple-negative breast cancer patient
Case Report: Possible association between dermatomyositis and Trastuzumab Deruxtecan therapy of triple-negative breast cancer patient Open
Introduction we present the case of the first documented occurrence of concurrent dermatomyositis and interstitial pneumonia associated with Trastuzumab Deruxtecan (T-DXd) therapy. We hypothesize that T-DXd likely induced an autoimmune res…
View article: Serum lactate dehydrogenase and rapidly progressive interstitial lung disease are associated with increased mortality in anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis
Serum lactate dehydrogenase and rapidly progressive interstitial lung disease are associated with increased mortality in anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis Open
Objective This study aims to evaluate the clinical characteristics and prognostic significance of serum lactate dehydrogenase (LDH) in patients with anti-MDA5+ dermatomyositis (anti-MDA5+ DM). Methods We assessed 246 consecutive patients w…
View article: Dermatomyositis: Review and Considerations in Older Adults
Dermatomyositis: Review and Considerations in Older Adults Open
Dermatomyositis (DM) is an idiopathic inflammatory myopathy characterized by prominent skin lesions, muscle weakness, and clinically heterogeneous systemic manifestations. Among patients with DM, the male-to-female ratio is 2:1. Juvenile d…
View article: Nailfold videocapillaroscopy abnormalities in autoimmune inflammatory myopathy subsets
Nailfold videocapillaroscopy abnormalities in autoimmune inflammatory myopathy subsets Open
Objectives Nailfold videocapillaroscopy (NVC) alterations have been described in autoimmune inflammatory myopathies (AIM). This study aimed to describe NVC abnormalities in AIM subsets using a clinico-sero-pathological approach. Methods We…
View article: HEMATOLOGIC MANIFESTATIONS OF PEDIATRIC CONNECTIVE TISSUE DISEASES
HEMATOLOGIC MANIFESTATIONS OF PEDIATRIC CONNECTIVE TISSUE DISEASES Open
The hematopoietic system is frequently affected by autoimmune connective tissue diseases in children, including juvenile systemic lupus erythematosus (JSLE), juvenile dermatomyositis (JDM), juvenile scleroderma (localized and systemic), an…
View article: HEMATOLOGIC MANIFESTATIONS OF PEDIATRIC CONNECTIVE TISSUE DISEASES
HEMATOLOGIC MANIFESTATIONS OF PEDIATRIC CONNECTIVE TISSUE DISEASES Open
The hematopoietic system is frequently affected by autoimmune connective tissue diseases in children, including juvenile systemic lupus erythematosus (JSLE), juvenile dermatomyositis (JDM), juvenile scleroderma (localized and systemic), an…
View article: Large scale quantification of autoantibodies using array-based immunoabsorption method in idiopathic inflammatory myopathies (IIM) 3072
Large scale quantification of autoantibodies using array-based immunoabsorption method in idiopathic inflammatory myopathies (IIM) 3072 Open
Description Autoantibodies are important biomarkers for diagnosis and diseases activity evaluation in IIM. Current immunoassays have limitations in terms of sensitivity and quantification. Here we developed an array-based immunoabsorption …
View article: 126 Itch of Dermatomyositis treated with topical JAK inhibitor
126 Itch of Dermatomyositis treated with topical JAK inhibitor Open