Bulbar palsy
View article: From intractable hiccups to optic neuritis: paraneoplastic neuromyelitis optica with leptomeningeal carcinomatosis in the setting of immature ovarian teratoma
From intractable hiccups to optic neuritis: paraneoplastic neuromyelitis optica with leptomeningeal carcinomatosis in the setting of immature ovarian teratoma Open
Background: Paraneoplastic syndromes are associated with 10% of ovarian cancers. Neuromyelitis optica spectrum disorders (NMOSD), which can present with vision changes, paraplegia, vomiting, and/or intractable hiccups, are rarely associate…
View article: Spinocerebellar Ataxia Type 3 Accompanied by Amyotrophic Lateral Sclerosis: A Case Report and Comprehensive Literature Review
Spinocerebellar Ataxia Type 3 Accompanied by Amyotrophic Lateral Sclerosis: A Case Report and Comprehensive Literature Review Open
Spinocerebellar ataxia type 3 (SCA3) is a hereditary neurodegenerative disorder characterized by cerebellar ataxia, whereas amyotrophic lateral sclerosis (ALS) is a progressive motor neuron disease. We herein report a 62-year-old man with …
View article: Acoustic Vowel Metrics as Correlates of Dysphagia and Dysarthria in Brainstem Neurodegenerative Diseases
Acoustic Vowel Metrics as Correlates of Dysphagia and Dysarthria in Brainstem Neurodegenerative Diseases Open
Background/Objectives: Swallowing and speech rely on shared brainstem circuits coordinating oropharyngeal motor functions. In neurodegenerative diseases affecting the brainstem—such as progressive supranuclear palsy (PSP), amyotrophic late…
View article: Traditional Korean Medicine Treatment Using Electroacupuncture for a Patient with Abducens Nerve Palsy Caused by Rupture of a Vertebral Artery Dissecting Aneurysm: A Case Report
Traditional Korean Medicine Treatment Using Electroacupuncture for a Patient with Abducens Nerve Palsy Caused by Rupture of a Vertebral Artery Dissecting Aneurysm: A Case Report Open
Objective: To describe the clinical improvement of traditional Korean medicine for treating abducens nerve palsy caused by ruptured vertebral artery dissecting aneurysms.Methods: Patients received conventional treatment followed by acupunc…
View article: Amyotrophic lateral sclerosis: A clinical review
Amyotrophic lateral sclerosis: A clinical review Open
A neurodegenerative disease of the motor pathways, amyotrophic lateral sclerosis (ALS) always results in death within a few years of start. 10% of ALS cases are familial variants of the illness (FALS), while the majority of ALS cases are s…
View article: Amyotrophic lateral sclerosis: A clinical review
Amyotrophic lateral sclerosis: A clinical review Open
A neurodegenerative disease of the motor pathways, amyotrophic lateral sclerosis (ALS) always results in death within a few years of start. 10% of ALS cases are familial variants of the illness (FALS), while the majority of ALS cases are s…
View article: A case report on Ayurvedic management of progressive bulbar palsy-A rare amyotrophic lateral sclerosis phenotype
A case report on Ayurvedic management of progressive bulbar palsy-A rare amyotrophic lateral sclerosis phenotype Open
This case report is the description of a devastating illness, Progressive Bulbar Palsy (PBP) of a sixty-seven years old male patient. He presented with complaints of slurred speech, hearing impairment, generalised weakness of limbs, weaken…
View article: Bulbar Palsy as a Presentation of Medullary Ischemic Stroke: An Educational Case Report
Bulbar Palsy as a Presentation of Medullary Ischemic Stroke: An Educational Case Report Open
Aims: Medullary ischemic strokes are uncommon and often present with complex neurological symptoms. The clinical characteristics of bulbar palsy, which can be a common presentation for other diseases, add to the difficulties in diagnosing …
View article: Relationship Between Voice Analysis and Functional Status in Patients with Amyotrophic Lateral Sclerosis
Relationship Between Voice Analysis and Functional Status in Patients with Amyotrophic Lateral Sclerosis Open
Background: Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disease affecting both upper and lower motor neurons, with bulbar dysfunction manifesting in up to 80% of patients. Dysarthria, characterized by impaired sp…
View article: Atypical bulbar myasthenia gravis in an elderly male unmasked by levofloxacin: a diagnostic challenge
Atypical bulbar myasthenia gravis in an elderly male unmasked by levofloxacin: a diagnostic challenge Open
Background: Myasthenia gravis (MG) is an autoimmune neuromuscular disorder that typically presents with ocular symptoms. Isolated bulbar symptoms, such as dysphagia and dysarthria, are rare, and most commonly seen in men with late-onset MG…
View article: Progressive Bulbar Palsy (PBP) or Bulbar Onset MND: “A Case Report”
Progressive Bulbar Palsy (PBP) or Bulbar Onset MND: “A Case Report” Open
A BSTRACT A patient with enhancing bulbar palsy, a type of efferent neuron disease that causes hypertrophy and twitching of the tongue’s musculature, dysphagia, dysarthria, and an excessive buildup of secretions, is described. Enhancing bu…
View article: Congenital Myasthenia Gravis Presenting as Refractory Seizures and Respiratory Failure: A Case Report
Congenital Myasthenia Gravis Presenting as Refractory Seizures and Respiratory Failure: A Case Report Open
Congenital myasthenia syndrome (CMS) is an inherited disorder that involves muscle weakness and fatigue. It can present at birth or late childhood and has variable presentations and severity. It consists of a heterogeneous group of disorde…
View article: Numbness on the Medical Take: An Atypical Presentation of Guillain‐Barre Syndrome With Unilateral Paraesthesia and Rapid Progression to Bulbar Palsy: A Case Report
Numbness on the Medical Take: An Atypical Presentation of Guillain‐Barre Syndrome With Unilateral Paraesthesia and Rapid Progression to Bulbar Palsy: A Case Report Open
Guillain‐Barré syndrome (GBS) is characterized classically by progressive and symmetrical motor weakness and areflexia. We describe a case of GBS with initially preserved reflexes and power, leading to delayed diagnosis, who latterly requi…
View article: Bulbar Palsy Due to Pachymeningitis as an Initial Manifestation of Granulomatosis With Polyangiitis
Bulbar Palsy Due to Pachymeningitis as an Initial Manifestation of Granulomatosis With Polyangiitis Open
View article: Temporal Pattern of Individual Neurological Function Recovery in Guillain–Barré Syndrome
Temporal Pattern of Individual Neurological Function Recovery in Guillain–Barré Syndrome Open
Background: There is paucity of studies on the temporal pattern of recovery of facial, bulbar, sensory, motor, and autonomic dysfunction in Guillain–Barré syndrome (GBS), although many studies have reported short- and long-term functional …
View article: MYASTHENIA GRAVIS PRESENTS AS BULBAR PALSY WITHOUT THYMOMA
MYASTHENIA GRAVIS PRESENTS AS BULBAR PALSY WITHOUT THYMOMA Open
Myasthenia gravis is the most common neuromuscular junction disorder associated with autoimmune diseases, although around 10-15% of patients have no detectable antibodies, and 85% of patients have antibodies. Bulbar symptoms are not common…
View article: Clinical spreading of muscle weakness in amyotrophic lateral sclerosis (ALS): a study in 910 patients
Clinical spreading of muscle weakness in amyotrophic lateral sclerosis (ALS): a study in 910 patients Open
View article: A case of variant of GBS with positive serum ganglioside GD3 IgG antibody
A case of variant of GBS with positive serum ganglioside GD3 IgG antibody Open
View article: Listener effort quantifies clinically meaningful progression of dysarthria in people living with amyotrophic lateral sclerosis
Listener effort quantifies clinically meaningful progression of dysarthria in people living with amyotrophic lateral sclerosis Open
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative motor neuron disease that causes progressive muscle weakness. Progressive bulbar dysfunction causes dysarthria and thus social isolation, reducing quality of life. The Everything A…
View article: Autonomic Dysfunction in Amyotrophic Lateral Sclerosis – A Case-Control Study
Autonomic Dysfunction in Amyotrophic Lateral Sclerosis – A Case-Control Study Open
Introduction. This study aimed to explore autonomic nervous system involvement in amyotrophic lateral sclerosis (ALS) pa- tients by evaluating sympathetic skin response (SSR). Materials and Methods. The study included 35 sporadic (ALS) pat…
View article: Case Report: A rare treatable metabolic syndrome (Brown-Vialetto-Van Laere syndrome) masquerading as chronic inflammatory demyelinating polyneuropathy from Saudi Arabia
Case Report: A rare treatable metabolic syndrome (Brown-Vialetto-Van Laere syndrome) masquerading as chronic inflammatory demyelinating polyneuropathy from Saudi Arabia Open
Background Brown-Vialetto-Van Laere (BVVL) syndrome is an extremely rare autosomal recessive progressive motoneuron disease that is caused by a defect in the riboflavin transporter genes SLC52A2 and SLC52A3. BVVL syndrome has a variable ag…
View article: Diagnosis of Acute Bulbar Palsy Plus Syndrome: A Rare Variant of Guillain–barre Syndrome
Diagnosis of Acute Bulbar Palsy Plus Syndrome: A Rare Variant of Guillain–barre Syndrome Open
Presenting case of a 11-year-old girl with sudden cranial nerve weakness, universal areflexia but without limb pain or weakness. NCV showed subclinical axonal involvement in limbs. A diagnosis of acute bulbar palsy plus–GBS was made and ch…
View article: Guillain-Barré syndrome with overlap between the finger drop variant and acute bulbar palsy: a case report
Guillain-Barré syndrome with overlap between the finger drop variant and acute bulbar palsy: a case report Open
Background Guillain-Barré syndrome (GBS) encompasses diverse variants, and the overlap between these variants often makes the diagnosis of GBS difficult. We report a case of GBS overlapping with both the finger drop variant and acute bulba…
View article: Atypical antinuclear matrix protein 2-positive dermatomyositis presenting with anasarca and bulbar weakness after COVID-19 infection requiring mechanical ventilation
Atypical antinuclear matrix protein 2-positive dermatomyositis presenting with anasarca and bulbar weakness after COVID-19 infection requiring mechanical ventilation Open
A 28-year-old female presented with a sixweek history of rapid onset proximal muscle weakness, dysphagia, and inflammatory rash (heliotropic rash, Gottron papules, and livedo reticularis). Of note, three weeks prior to developing symptoms …
View article: Empirical pyridostigmine in a patient with difficult weaning from mechanical ventilation after traumatic brain injury
Empirical pyridostigmine in a patient with difficult weaning from mechanical ventilation after traumatic brain injury Open
We present a 30-year-old male who sustained a mild traumatic brain injury and then was intubated due to deterioration of consciousness. A head CT scan revealed mild brain oedema, a fractured nasal bone and mild left thoracic wall haematoma…
View article: Rare Clinical Image of Kennedy’s Syndrome
Rare Clinical Image of Kennedy’s Syndrome Open
Sir, Bulbar motor neuron disease, often referred to as bulbar palsy or bulbar onset motor neuron disease, is a subtype of motor neuron disease (MND) that primarily affects the motor neurons located in the bulbar region of the brainstem.[1]…
View article: Analysis of Traditional Chinese Medicine Symptoms in Children with Spastic Cerebral Palsy: A Data Mining Study
Analysis of Traditional Chinese Medicine Symptoms in Children with Spastic Cerebral Palsy: A Data Mining Study Open
This study identified the core symptom of spastic CP and tentatively suggests that the clinical manifestations of spastic CP are essentially consistent with the TCM pattern "liver exuberance and spleen weakness". This finding has facilitat…
View article: Predictors of Mortality in Veterans with Amyotrophic Lateral Sclerosis: Respiratory Status and Speech Disorder at Presentation
Predictors of Mortality in Veterans with Amyotrophic Lateral Sclerosis: Respiratory Status and Speech Disorder at Presentation Open
BACKGROUND There is a lack of accurate models to predict amyotrophic lateral sclerosis (ALS) disease course and outcomes. As a result, risk assessment and counseling, the timing of interventions, and their stratification in clinical trials…
View article: Progressive Ponto-bulbar Palsy in Childhood
Progressive Ponto-bulbar Palsy in Childhood Open
View article: Pattern of Clinical Profile and Outcome of Gillian Barre Syndrome in Sudanese Patients
Pattern of Clinical Profile and Outcome of Gillian Barre Syndrome in Sudanese Patients Open
Introduction: Guillian Barre'-Syndrome (GBS) is an acute, autoimmune disease affecting spinal roots and peripheral nerves, characterized by a rapidly progressive, ascending weakness of the extremity, trunk and even respiratory and facial m…