Hepatic dysfunction
View article: Quantifying treatment value under IRA: a case study of rifaximin for the treatment of overt hepatic encephalopathy using QALY and non-QALY measures
Quantifying treatment value under IRA: a case study of rifaximin for the treatment of overt hepatic encephalopathy using QALY and non-QALY measures Open
Rifaximin is a cost-effective treatment for preventing OHE recurrence in adults using QALY and non-QALY health benefit measures.
View article: Interplay among lipoprotein(a), hepatic and vascular damage in individuals with metabolic dysfunction
Interplay among lipoprotein(a), hepatic and vascular damage in individuals with metabolic dysfunction Open
View article: Independent effects of Metformin and Dapagliflozin on Fetuin-A, hepatic and pancreatic fat, and hepatic fibrosis in Asian Indians with type 2 diabetes
Independent effects of Metformin and Dapagliflozin on Fetuin-A, hepatic and pancreatic fat, and hepatic fibrosis in Asian Indians with type 2 diabetes Open
View article: Hypoglycemic Encephalopathy With Multisystem Organ Dysfunction in an Infant With MEGD(H)EL Syndrome
Hypoglycemic Encephalopathy With Multisystem Organ Dysfunction in an Infant With MEGD(H)EL Syndrome Open
View article: Hepatic necrosis and dysfunction following angioembolization in a trauma-related mortality
Hepatic necrosis and dysfunction following angioembolization in a trauma-related mortality Open
View article: Akkermansia Muciniphila vs. Fluoxetine: Amelioration of Depression-like Behaviors and Cognitive Dysfunction Through Distinct Neurobiological Mechanisms
Akkermansia Muciniphila vs. Fluoxetine: Amelioration of Depression-like Behaviors and Cognitive Dysfunction Through Distinct Neurobiological Mechanisms Open
View article: Correction: The lipoxin A4 agonist BML-111 attenuates acute hepatic dysfunction induced by cecal ligation and puncture in rats
Correction: The lipoxin A4 agonist BML-111 attenuates acute hepatic dysfunction induced by cecal ligation and puncture in rats Open
View article: Jaundice In Animals
Jaundice In Animals Open
Jaundice is derived from French word ‘Jaune’ meaning yellow. Jaundice is also
View article: Paroxysmal Nocturnal Hemoglobinuria-Driven Hepatic Vein Thrombosis: A Case of Budd-Chiari Syndrome in Disguise
Paroxysmal Nocturnal Hemoglobinuria-Driven Hepatic Vein Thrombosis: A Case of Budd-Chiari Syndrome in Disguise Open
View article: Terminal Lucidity: A Ketogenic Hypothesis Requiring Intact Hepatic Function
Terminal Lucidity: A Ketogenic Hypothesis Requiring Intact Hepatic Function Open
Terminal lucidity (TL), or paradoxical lucidity, refers to the unexpected and temporary return of coherent communication or cognitive clarity in individuals with advanced dementia shortly before death. TL has been widely reported in hospic…
View article: Comparison of efficacy of rifaximin, probiotics and l-ornithine l-aspartate in overt hepatic encephalopathy: a randomized, phase IV, lactulose controlled clinical trial
Comparison of efficacy of rifaximin, probiotics and l-ornithine l-aspartate in overt hepatic encephalopathy: a randomized, phase IV, lactulose controlled clinical trial Open
Background Pakistan has a high prevalence of HCV and HBV, causing cirrhosis, leading to hepatic encephalopathy in approximately 30–45% of cirrhotic patients. Overt hepatic encephalopathy (OHE) is a serious type of hepatic encephalopathy th…
View article: Terminal Lucidity: A Ketogenic Hypothesis Requiring Intact Hepatic Function
Terminal Lucidity: A Ketogenic Hypothesis Requiring Intact Hepatic Function Open
Terminal lucidity (TL), or paradoxical lucidity, refers to the unexpected and temporary return of coherent communication or cognitive clarity in individuals with advanced dementia shortly before death. TL has been widely reported in hospic…
View article: Hepatic Dysfunction in Dengue Fever and Dengue Hemorrhagic Fever: A Cross-Sectional Study at a Tertiary-level Hospital
Hepatic Dysfunction in Dengue Fever and Dengue Hemorrhagic Fever: A Cross-Sectional Study at a Tertiary-level Hospital Open
Background: Dengue is the most prevalent mosquito-borne viral infection, endemic in South-East Asia and found in tropical and subtropical regions worldwide, predominantly in urban and peri-urban areas. In Bangladesh, dengue has emerged as …
View article: Initial Aspartate Aminotransferase-to-platelet Ratio Index is Associated with Sepsis-associated Liver Dysfunction in Adult Patients with Sepsis: A Retrospective Cohort Study
Initial Aspartate Aminotransferase-to-platelet Ratio Index is Associated with Sepsis-associated Liver Dysfunction in Adult Patients with Sepsis: A Retrospective Cohort Study Open
View article: Assessment of thyroid dysfunction as a late complication after hematopoietic stem cell transplantation in pediatric patients
Assessment of thyroid dysfunction as a late complication after hematopoietic stem cell transplantation in pediatric patients Open
View article: Comprehensive Ayurvedic Management of Hepatic Fibrosis (Grade III): A Case Report
Comprehensive Ayurvedic Management of Hepatic Fibrosis (Grade III): A Case Report Open
Background: The prevalence of hepatic fibrosis is increasing worldwide, with significant geographic variation. It is necessary to better understand the risk factors and how to prevent and mitigate the disease worldwide to combat the advanc…
View article: Electrocardiographic T-Wave Changes in Patients with Liver Cirrhosis: A Marker of Decompensation
Electrocardiographic T-Wave Changes in Patients with Liver Cirrhosis: A Marker of Decompensation Open
Background: Cirrhotic cardiomyopathy is an underrecognized complication that affects nearly half of patients with liver cirrhosis. Electrocardiographic T-wave changes and diastolic dysfunction may serve as an early sign of cardiac involvem…
View article: Feasibility and Safety of <scp>Cytosorb</scp> Application in Patients With Acute Liver Failure
Feasibility and Safety of <span>Cytosorb</span> Application in Patients With Acute Liver Failure Open
Background and Aims Acute liver failure (ALF) is a rare, life‐threatening condition with high mortality and limited therapeutic options beyond liver transplantation. Cytosorb adsorber can be easily applied to continuous renal replacement t…
View article: Apremilast attenuates hepatic steatosis and metabolic dysfunction in a murine model of MASLD: Implications for patients with Psoriatic disease
Apremilast attenuates hepatic steatosis and metabolic dysfunction in a murine model of MASLD: Implications for patients with Psoriatic disease Open
Apremilast ameliorates hepatic dysfunction, improves insulin sensitivity, and reduces systemic metabolic dysfunction in a murine MASLD model. These findings support its therapeutic potential in PsD patients with metabolic disease, offering…
View article: To explore the dose optimization of imatinib in children with liver dysfunction based on the PBPK model
To explore the dose optimization of imatinib in children with liver dysfunction based on the PBPK model Open
Aims: This study aimed to characterize the pharmacokinetics of imatinib in paediatric patients with hepatic impairment, a population for whom evidence-based dosing guidance is currently lacking, in order to inform safe and effective prescr…
View article: Delirium Tremens with Hepatic Encephalopathy, a Diagnostic Dilemma: A Case Series
Delirium Tremens with Hepatic Encephalopathy, a Diagnostic Dilemma: A Case Series Open
Hepatic encephalopathy is brain dysfunction caused by liver damage that can occur due to an array of etiological factors. Delirium tremens, on the other hand, is a severe and life-threatening form of alcohol withdrawal. These two condition…
View article: Porphyrias: Pathophysiology and clinical management recommendations for hepatologists
Porphyrias: Pathophysiology and clinical management recommendations for hepatologists Open
In humans, an enzyme dysfunction in heme biosynthesis results in a heterogenous group of diseases collectively known as porphyrias. From a clinical standpoint, porphyrias can be classified as erythropoietic (congenital erythropoietic porph…
View article: Editorial: Comparable Hepatic Fibrosis Risk Demands Equal Vigilance in Lean and Non‐Lean Patients With Metabolic Dysfunction‐Associated Steatotic Liver Disease
Editorial: Comparable Hepatic Fibrosis Risk Demands Equal Vigilance in Lean and Non‐Lean Patients With Metabolic Dysfunction‐Associated Steatotic Liver Disease Open
View article: Acute cholangitis due to common bile duct stones: Clinical outcomes in patients with and without concurrent acute pancreatitis
Acute cholangitis due to common bile duct stones: Clinical outcomes in patients with and without concurrent acute pancreatitis Open
BACKGROUND Patients with concurrent acute biliary pancreatitis (ABP) and acute cholangitis (AC) may experience exacerbated clinical consequences due to bile duct stones. However, studies exploring this topic remain limited. AIM To compare …
View article: Editorial: Comparable Hepatic Fibrosis Risk Demands Equal Vigilance in Lean and Non‐Lean Patients With Metabolic Dysfunction‐Associated Steatotic Liver Disease—Authors' Reply
Editorial: Comparable Hepatic Fibrosis Risk Demands Equal Vigilance in Lean and Non‐Lean Patients With Metabolic Dysfunction‐Associated Steatotic Liver Disease—Authors' Reply Open
View article: An Uncommon Site, a Common Foe: Isolated Hepatic Tuberculosis in a HIV Positive Adult
An Uncommon Site, a Common Foe: Isolated Hepatic Tuberculosis in a HIV Positive Adult Open
View article: The association between hepatic fibrosis indicators and subclinical carotid atherosclerosis in the population with metabolic dysfunction-associated steatotic liver disease under 50 years old
The association between hepatic fibrosis indicators and subclinical carotid atherosclerosis in the population with metabolic dysfunction-associated steatotic liver disease under 50 years old Open
View article: Carvedilol decreases hepatic vascular resistance by reducing fibrogenesis and reversing endothelial dysfunction in cirrhotic rats.
Carvedilol decreases hepatic vascular resistance by reducing fibrogenesis and reversing endothelial dysfunction in cirrhotic rats. Open
View article: Nutritional intervention with perennial ryegrass alleviates hepatic dysfunction by modulating lipid metabolism: insights from gut-liver axis
Nutritional intervention with perennial ryegrass alleviates hepatic dysfunction by modulating lipid metabolism: insights from gut-liver axis Open
View article: Zinc Phosphide Poisoning in Pregnancy: A Rare Case Report From Nepal
Zinc Phosphide Poisoning in Pregnancy: A Rare Case Report From Nepal Open
Zinc phosphide (Zn 3 P 2 ) poisoning during pregnancy is exceedingly unusual and potentially lethal, with no previously known occurrences globally. We present a 26‐year‐old woman, gravida 2 para 1, at 29 weeks gestation, who took 15 g of Z…