Dental research
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The Biology of <i>Streptococcus mutans</i> Open
As a major etiological agent of human dental caries, Streptococcus mutans resides primarily in biofilms that form on the tooth surfaces, also known as dental plaque. In addition to caries, S. mutans is responsible for cases of infective en…
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Terminology of Erosive Tooth Wear: Consensus Report of a Workshop Organized by the ORCA and the Cariology Research Group of the IADR Open
Our understanding of erosive tooth wear and its contributing factors has evolved considerably over the last decades. New terms have been continuously introduced, which frequently describe the same aspects of this condition, whereas other t…
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Clinical Outcomes of Zirconia Dental Implants: A Systematic Review Open
To determine the survival rate and marginal bone loss (MBL) of zirconia dental implants restored with single crowns or fixed dental prostheses. An electronic search was conducted up to November 2015 (without any restriction regarding the p…
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Role of Saliva and Salivary Diagnostics in the Advancement of Oral Health Open
The objective of this article was to provide an account of some of the developments related to saliva over the first 100 years of the Journal of Dental Research and to outline some of the many biomarkers identified in saliva in the last fe…
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Sugar Industry Influence on the Scientific Agenda of the National Institute of Dental Research’s 1971 National Caries Program: A Historical Analysis of Internal Documents Open
The NCP was a missed opportunity to develop a scientific understanding of how to restrict sugar consumption to prevent tooth decay. A key factor was the alignment of research agendas between the NIDR and the sugar industry. This historical…
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Targeting <i>S. mutans</i> biofilms: a perspective on preventing dental caries Open
This review aims to provide an overview of the current small molecule strategies used for targeting S. mutans biofilms, and a perspective of the future for the field.
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Stem Cells of Dental Origin: Current Research Trends and Key Milestones towards Clinical Application Open
Dental Mesenchymal Stem Cells (MSCs), including Dental Pulp Stem Cells (DPSCs), Stem Cells from Human Exfoliated Deciduous teeth (SHED), and Stem Cells From Apical Papilla (SCAP), have been extensively studied using highly sophisticated in…
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Detection Methods for Early Caries Diagnosis: A Systematic Review and Meta-Analysis Open
The aim was to appraise the evidence on the performance of various means for the detection of incipient caries in vivo. Five databases of published and unpublished research were searched for studies from January 2000 to October 2019. Searc…
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Oral Health Effects of Combusted and Smokeless Tobacco Products Open
The oral cavity is usually the first part of a consumer’s body exposed to the constituents of tobacco products or their emissions. Consequently, the oral cavity is a frequent site for carcinogenic, microbial, immunologic, and clinical effe…
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Inclusion oral health: Advancing a theoretical framework for policy, research and practice Open
In response to headlines about the oral health of persons experiencing social exclusion resonating in high‐income countries, and research demonstrating the need for urgent action, a symposium entitled ‘International Perspectives on Sociall…
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<i>In vitro</i> biofilm models to study dental caries: a systematic review Open
The aim of this systematic review is to characterize and discuss key methodological aspects of in vitro biofilm models for caries-related research and to verify the reproducibility and dose-response of models considering the response to an…
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A systematic review and meta-analysis on ChatGPT and its utilization in medical and dental research Open
The observations indicate that ChatGPT has the ability to provide appropriate solutions to questions in the medical and dentistry areas, but researchers and doctors should cautiously assess its responses because they might not always be de…
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Investigating the association between stress, saliva and dental caries: a scoping review Open
There is lack of evidence about an association between stress-related changes in saliva and caries. Well-designed longitudinal studies with rigorous measurement technics for stress, saliva and dental caries are necessary. This will help to…
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Dental Research Waste in Design, Analysis, and Reporting: A Scoping Review Open
Research waste is highly prevalent across biomedical investigations. We aimed to assess the evidence on the extent of research waste in dental research. We performed a scoping review of empirical evaluations of dental studies assessing the…
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Innovative Dental Stem Cell‐Based Research Approaches: The Future of Dentistry Open
Over the past decade, the dental field has benefited from recent findings in stem cell biology and tissue engineering that led to the elaboration of novel ideas and concepts for the regeneration of dental tissues or entire new teeth. In pa…
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Update on 13 Syndromes Affecting Craniofacial and Dental Structures Open
Care of individuals with syndromes affecting craniofacial and dental structures are mostly treated by an interdisciplinary team from early childhood on. In addition to medical and dental specialists that have a vivid interest in these synd…
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Surveys on Reporting Guideline Usage in Dental Journals Open
The objectives of this study were 1) to find out if and how authors and peer reviewers for dental journals are encouraged to use reporting guidelines (RGs); 2) to identify factors related to RG endorsement; and 3) to assess the knowledge, …
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Global research interest regarding silver diamine fluoride in dentistry: A bibliometric analysis Open
This paper presents an overview of scientific evidence and impact of SDF use in dentistry. SDF attracts a growing interest globally and there has been a steady increase in scientific research into its use in dental practice.
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How to Intervene in the Caries Process in Older Adults: A Joint ORCA and EFCD Expert Delphi Consensus Statement Open
Aim: To provide recommendations for dental clinicians for the management of dental caries in older adults with special emphasis on root caries lesions. Methods: A consensus workshop followed by a Delphi consensus process were conducted wit…
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Current State and Challenges of the Global Outcomes of Dental Caries Research in the Meta-Omics Era Open
Despite significant healthcare advances in the 21 st century, the exact etiology of dental caries remains unsolved. The past two decades have witnessed a tremendous growth in our understanding of dental caries amid the advent of revolution…
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Pre-Clinical Models in Implant Dentistry: Past, Present, Future Open
Biomedical research seeks to generate experimental results for translation to clinical settings. In order to improve the transition from bench to bedside, researchers must draw justifiable conclusions based on data from an appropriate mode…
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Developments in resin-based composites Open
With the phasing down of dental amalgam use in response to the Minamata Convention, it is likely that resin-based composite restoratives will be the dental material of choice for the direct restoration of compromised dentition in the UK, a…
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Body Mass Index and Dental Caries: A Systematic Review Open
No consensus was reached in the relationship between BMI and dental caries in the present review due to varied associationsHow to cite this article: Shivakumar S, Srivastava A, Shivakumar GC. Body Mass Index and Dental Caries: A Systematic…
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Top 100 cited systematic reviews and meta-analyses in dentistry Open
Objective: The purpose of the present study was to identify the 100 top cited systematic reviews and meta-analyses on dental journals so as to gain insight into the influential publications in dentistry.Material and methods: The Web of Sci…
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Global Foot-and-Mouth Disease Research Update and Gap Analysis: 1 - Overview of Global Status and Research Needs Open
The Global Foot-and-mouth disease (FMD) Research Alliance periodically reviews the state of FMD research to assess progress and to identify new priorities. In this supplement we provide an update of global FMD research, comprising (i) this…
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Update on Electronic Dental Record and Clinical Computing Adoption Among Dental Practices in the United States Open
This study sought to re-characterize trends and factors affecting electronic dental record (EDR) and technologies adoption by dental practices and the impact of the Health Information Technology for Economic and Clinical Health (HITECH) ac…
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ARTIFICIAL INTELLIGENCE IN DENTISTRY: CURRENT CONCEPTS AND A PEEP INTO THE FUTURE. Open
20Dec 2018 ARTIFICIAL INTELLIGENCE IN DENTISTRY: CURRENT CONCEPTS AND A PEEP INTO THE FUTURE. Bijo Alexander and Sunil John. Professor and Head ,Department of Oral Pathology and Microbiology. Reader,Department of Periodontics, Noorul Islam…
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Ethical guidelines, animal profile, various animal models used in periodontal research with alternatives and future perspectives Open
Laboratory animal models serve as a facilitator to investigate the etiopathogenesis of periodontal disease, are used to know the efficacy of reconstructive and regenerative procedures, and are also helpful in evaluation of newer therapeuti…
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Provision of specific dental procedures by general dentists in the National Dental Practice-Based Research Network: questionnaire findings Open
As a group, GDs provide a comprehensive range of procedures. However, provision by individual dentists is substantively related to certain dentist, practice, and patient characteristics. A large number and broad range of factors seem to in…
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Oral Health Disparities: A Perspective From the National Institute of Dental and Craniofacial Research Open
The author discusses improvements in the prevention, diagnosis, and treatment of oral diseases in the U.S. despite significant oral health disparities. Topics include the tendency for dental caries and periodontal disease to be the most co…