Primary treatment
View article: Carbon Ion Radiotherapy for Unresectable Primary or Recurrent Soft Tissue Sarcomas: Long-Term Outcomes based on the Local Effect Model System
Carbon Ion Radiotherapy for Unresectable Primary or Recurrent Soft Tissue Sarcomas: Long-Term Outcomes based on the Local Effect Model System Open
Background The application of carbon ion radiotherapy (CIRT) for unresectable primary or recurrent soft tissue sarcoma (STS) remains controversial and existing data are limited. We herein present our institutional experience with CIRT for …
View article: Primary treatment of fishery wastewater using chemical and natural coagulants
Primary treatment of fishery wastewater using chemical and natural coagulants Open
View article: Primary Care Providers Perspectives of GLP-1 Receptor Agonists to Manage Recurrent Weight Gain after Metabolic Bariatric Surgery – a Qualitative Study
Primary Care Providers Perspectives of GLP-1 Receptor Agonists to Manage Recurrent Weight Gain after Metabolic Bariatric Surgery – a Qualitative Study Open
Introduction Recurrent weight gain after metabolic bariatric surgery (MBS) affects 20–25% of patients, with research indicating that up to 87% of patients experience some post-MBS weight gain. Glucagon-like peptide-1 receptor agonists (GLP…
View article: THE COMMISSIONING AND FIRST CLINICAL TREATMENT WITH MONACO PROTON TREATMENT PLANNING SYSTEM ON A COMPACT PROTON THERAPY SYSTEM
THE COMMISSIONING AND FIRST CLINICAL TREATMENT WITH MONACO PROTON TREATMENT PLANNING SYSTEM ON A COMPACT PROTON THERAPY SYSTEM Open
View article: The management of pediatric Chiari I malformation with concomitant hydrocephalus: a multicenter retrospective analysis
The management of pediatric Chiari I malformation with concomitant hydrocephalus: a multicenter retrospective analysis Open
Background Chiari I malformation (CIM) rarely occurs alongside hydrocephalus (7–10%), and the relationship between the two—whether one is the cause or the effect of the other—remains contentious. Consequently, the optimal treatment approac…
View article: Supplementary Figure S4 from Novel Genomic Risk Stratification Model for Primary Gastrointestinal Stromal Tumors (GIST) in the Adjuvant Therapy Era
Supplementary Figure S4 from Novel Genomic Risk Stratification Model for Primary Gastrointestinal Stromal Tumors (GIST) in the Adjuvant Therapy Era Open
Supplementary Figure S4. RFS in primary localized gastric (A) and small bowel (B) GISTs by types of primary KIT and PDGFRA mutations [del: deletion; ex: exon; INS: insertion; PM: point mutation].
View article: High-intensity focused ultrasound as a combined approach for the treatment of recurrent low-grade endometrial stromal sarcoma: a case report and literature review
High-intensity focused ultrasound as a combined approach for the treatment of recurrent low-grade endometrial stromal sarcoma: a case report and literature review Open
Background Surgery is the primary treatment for Endometrial Stromal Sarcoma (ESS), however, a substantial proportion of patients with ESS experience recurrence or metastasis. Currently, surgery and local ablation are the main treatments fo…
View article: Primary Cardiac Osteosarcoma: Epidemiology, Diagnosis, and Management — A Narrative Review
Primary Cardiac Osteosarcoma: Epidemiology, Diagnosis, and Management — A Narrative Review Open
Purpose Primary cardiac sarcomas are exceedingly rare, with a very low incidence in the general population. A variety of sarcoma subtypes can originate in the heart, including angiosarcoma, rhabdomyosarcoma, leiomyosarcoma, fibrosarcoma, a…
View article: Embolization of the Middle Meningeal Artery As Primary Treatment for Chronic Subdural Hematoma in Older Filipino Adults
Embolization of the Middle Meningeal Artery As Primary Treatment for Chronic Subdural Hematoma in Older Filipino Adults Open
View article: A Podcast Discussion on Medical Treatment in R/M-SCCHN in the Year 2025—Standard and Considerations for an Individualized Treatment
A Podcast Discussion on Medical Treatment in R/M-SCCHN in the Year 2025—Standard and Considerations for an Individualized Treatment Open
Recurrent and/or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN) remains a disease with limited treatment options. Once salvage surgery or radiotherapy is no longer feasible, systemic medical therapy becomes the mainsta…
View article: Safety and efficacy of microwave ablation versus argon-helium cryoablation for the treatment of primary high-risk pulmonary nodules: a propensity score-matched study
Safety and efficacy of microwave ablation versus argon-helium cryoablation for the treatment of primary high-risk pulmonary nodules: a propensity score-matched study Open
View article: USE OF AESTHETIC-FUNCTIONAL SPACE MAINTAINER FOR EARLY LOSS OF PRIMARY TEETH: CASE REPORT
USE OF AESTHETIC-FUNCTIONAL SPACE MAINTAINER FOR EARLY LOSS OF PRIMARY TEETH: CASE REPORT Open
The early loss of primary teeth causes functional and aesthetic damage, ranging from the migration and/or inclination of adjacent teeth into the edentulous space, arch shortening, and antagonist extrusion, to phonetic and aesthetic impairm…
View article: The Negative Impact of Biofouling Factor of Water Treatment Process at Ceyranbatan Water Treatment Plant Complex
The Negative Impact of Biofouling Factor of Water Treatment Process at Ceyranbatan Water Treatment Plant Complex Open
Biofouling in water treatment systems is considered a serious technological challenge. The accumulation of various types of microorganisms, algae, and their residues on surfaces significantly reduces the efficiency of pipelines, various ty…
View article: Contemporary Management of Popliteal Artery Aneurysms: A Comprehensive Review
Contemporary Management of Popliteal Artery Aneurysms: A Comprehensive Review Open
Background and Objectives: current guidelines recommend surgical treatment for asymptomatic popliteal artery aneurysm > 20 mm in diameter, although without any suggestion about the preferred treatment choice. The two main treatment options…
View article: The Emerging Role of Ablation in the Treatment of Primary and Metastatic Cancer of the Liver
The Emerging Role of Ablation in the Treatment of Primary and Metastatic Cancer of the Liver Open
The traditional management of resectable colorectal liver metastases (CLMs) includes systemic therapy and curative (R0) surgery. Hepatocellular carcinoma (HCC) treatment options include R0 surgery, liver transplantation (LT), chemoembolisa…
View article: Radiotherapy for Primary Urethral Carcinoma (PUC): An Illustrative and Narrative Review
Radiotherapy for Primary Urethral Carcinoma (PUC): An Illustrative and Narrative Review Open
Primary urethral carcinoma (PUC) is a rare malignancy with a complex and site-specific management paradigm. While surgery remains the mainstay for many cases, advances in modern radiotherapy have facilitated organ preservation without comp…
View article: THE ROLE OF LAPAROSCOPIC SURGERY IN THE RECURRENCE OF CERVICAL CANCER
THE ROLE OF LAPAROSCOPIC SURGERY IN THE RECURRENCE OF CERVICAL CANCER Open
Resume. Objective of the Study: Based on multifactorial analysis, to evaluate the effectiveness, safety, and long-term outcomes (one-year mortality, overall survival, recurrence rate, localization, and time of recurrence) of minimally inva…
View article: Clinical Best Practices and Insights Toward Improving Recognition, Diagnosis and Treatment of Primary Axillary Hyperhidrosis (PAH)
Clinical Best Practices and Insights Toward Improving Recognition, Diagnosis and Treatment of Primary Axillary Hyperhidrosis (PAH) Open
Background: Primary axillary hyperhidrosis (PAH) is an underdiagnosed and underreported condition with symptoms beginning before age 25. We conducted a literature review and informal interviews with dermatology healthcare providers (HCPs…
View article: THE ROLE OF LAPAROSCOPIC SURGERY IN THE RECURRENCE OF CERVICAL CANCER
THE ROLE OF LAPAROSCOPIC SURGERY IN THE RECURRENCE OF CERVICAL CANCER Open
Resume. Objective of the Study: Based on multifactorial analysis, to evaluate the effectiveness, safety, and long-term outcomes (one-year mortality, overall survival, recurrence rate, localization, and time of recurrence) of minimally inva…
View article: Shared Decision‐Making in Treatment Selection in Multiple Myeloma in Spain: The <scp>PRISMMA</scp> Study
Shared Decision‐Making in Treatment Selection in Multiple Myeloma in Spain: The <span>PRISMMA</span> Study Open
Introduction Perceptions and experiences of shared decision‐making between patients and physicians in multiple myeloma (MM) care are not fully understood. A survey study was conducted to explore these perspectives in Spain. Methods Two ano…
View article: A Rare Case of Chemotherapy Combined with Immunotherapy for Dual Primary AFP-Positive Gastric Cancer and Synchronous Small Cell Lung Cancer
A Rare Case of Chemotherapy Combined with Immunotherapy for Dual Primary AFP-Positive Gastric Cancer and Synchronous Small Cell Lung Cancer Open
View article: Primary Reconstruction of Total Facial Nerve and Radical Parotidectomy Defects with Free Anterolateral Neuromyocutaneous Flap
Primary Reconstruction of Total Facial Nerve and Radical Parotidectomy Defects with Free Anterolateral Neuromyocutaneous Flap Open
View article: CLRD-02 PRIMARY CENTRAL NERVOUS TUMORS: CLINICAL EXPERIENCE IN THE SINGLE RADIOTHERAPY UNIT IN THE DRCONGO
CLRD-02 PRIMARY CENTRAL NERVOUS TUMORS: CLINICAL EXPERIENCE IN THE SINGLE RADIOTHERAPY UNIT IN THE DRCONGO Open
Introduction Primary and metastatic brain tumor are leading cause of cancer-related mortality and morbidity, and the primary indication for CNS radiotherapy. In Low-, Middle- Income Countries (LMICs), the limited access to advanced diagnos…
View article: TIP-28. Fine-tuning large language models using NCCN guidelines to aid primary CNS cancer treatment decisions
TIP-28. Fine-tuning large language models using NCCN guidelines to aid primary CNS cancer treatment decisions Open
Managing primary central nervous system (CNS) cancers presents a challenge, particularly for Rural or general oncologists (without access to a neuro-oncologist) who do not frequently encounter these conditions. NCCN guidelines continue to …
View article: Assessment of quality of life in patients with primary ovarian cancer during personalised treatment
Assessment of quality of life in patients with primary ovarian cancer during personalised treatment Open
Ovarian cancer (OC) ranks first among gynaecological cancers in terms of mortality, primarily due to late diagnosis and high recurrence rates.The objective: to analyse the quality of life (QoL) of patients with primary advanced OC dependin…
View article: Covered versus bare metal stents in treatment of primary common iliac disease.
Covered versus bare metal stents in treatment of primary common iliac disease. Open
View article: How does health literacy affect cancer treatment outcomes and patient management in primary care and oncology settings?
How does health literacy affect cancer treatment outcomes and patient management in primary care and oncology settings? Open
Limited health literacy is a key factor influencing cancer treatment outcomes and patient management, highlighting the need for improved communication strategies in healthcare settings.
View article: How does health literacy affect cancer treatment outcomes and patient management in primary care and oncology settings?
How does health literacy affect cancer treatment outcomes and patient management in primary care and oncology settings? Open
Limited health literacy is a key factor influencing cancer treatment outcomes and patient management, highlighting the need for improved communication strategies in healthcare settings.
View article: A review on management of Udavarta Yonivyapad w. s. r. to primary Dysmenorrhea
A review on management of Udavarta Yonivyapad w. s. r. to primary Dysmenorrhea Open
Udavarta Yonivyapad described in Ayurvedic classics, is a gynaecological disorder characterized by the upward movement of Vata leading to pain, suppression of natural urges, and menstrual irregularities. It shows significant resemblance to…
View article: Feasibility and Acceptability of Complete Vocal Technique-Voice Therapy as a Treatment for Primary Muscle Tension Dysphonia: A Feasibility Trial
Feasibility and Acceptability of Complete Vocal Technique-Voice Therapy as a Treatment for Primary Muscle Tension Dysphonia: A Feasibility Trial Open
gov/study/NCT05365126?patient=Muscle%20Tension%20Dysphonia&locStr=Nottingham,%20UK&lat=52.9540223&lng=-1.1549892&distance=50.