Human immunodeficiency virus (HIV)
View article: Intrinsic and extrinsic factors affecting the evolution of virulence in the HIV-associated opportunistic human fungal pathogen <i>Cryptococcus neoformans</i>.
Intrinsic and extrinsic factors affecting the evolution of virulence in the HIV-associated opportunistic human fungal pathogen <i>Cryptococcus neoformans</i>. Open
The fungus Cryptococcus neoformans is considered the leading cause of mortality in immunocompromised patients. While extensive research has unveiled the molecular epidemiology of C. neoformans, the influence of genetic and en…
View article: Simulation data related to the shared structural mechanisms of alternating access between the secondary peptide transporter SbmA and ABC transporters
Simulation data related to the shared structural mechanisms of alternating access between the secondary peptide transporter SbmA and ABC transporters Open
This record contains the MD simulation dataset for the paper with the title: Shared structural mechanisms of alternating access between the secondary peptide transporter SbmA and ABC transporters Authors Thijs W. Ettema
View article: Literacy and stigma of suicide among medical students in Tunisia
Literacy and stigma of suicide among medical students in Tunisia Open
Background: Medical students are future physicians, so it is important that they adopt compassionate attitudes toward suicidal patients and possess a good level of suicide literacy. we aimed to evaluate stigmatizing beliefs and suicide lit…
View article: Efficacy of raltegravir in achieving virological suppression at delivery in HIV-positive pregnant women: a systematic review and meta-analysis
Efficacy of raltegravir in achieving virological suppression at delivery in HIV-positive pregnant women: a systematic review and meta-analysis Open
Background The world’s first HIV integrase inhibitor, raltegravir (RAL), has been widely used for the treatment of HIV infection over the past 15 years, and continues benefiting people living with HIV (PLWH) today due to its efficient viro…
View article: What medications are recommended to prevent recurrence of HSV-2 viral meningitis?
What medications are recommended to prevent recurrence of HSV-2 viral meningitis? Open
Suppressive antiviral therapy appears to reduce recurrence risk of HSV-2 viral meningitis, with acyclovir, valacyclovir, and famciclovir as options, though clinical effectiveness varies and may require regimen adjustments.
View article: Anaphylaxis During CAR T‐Cell Infusion in an HIV‐Positive Patient With High‐Grade B‐Cell Lymphoma: A Case Report and Literature Review
Anaphylaxis During CAR T‐Cell Infusion in an HIV‐Positive Patient With High‐Grade B‐Cell Lymphoma: A Case Report and Literature Review Open
Chimeric antigen receptor (CAR) T‐cell therapy is a highly effective treatment for relapsed or refractory large B‐cell lymphoma (LBCL), but clinical experience in people living with HIV (PLWH) remains limited due to their exclusion from pi…
View article: Les comportements face au VIH et autres IST des travailleuses et travailleurs du sexe en Suisse. Enquête SWAN 2016
Les comportements face au VIH et autres IST des travailleuses et travailleurs du sexe en Suisse. Enquête SWAN 2016 Open
Pour la première fois en 2016, une enquête a été menée auprès des travailleuses et des travailleurs du sexe (TS) exerçant en Suisse. Cette étude, nommée SWAN (Sex Workers ANswers), s’inscrit dans le dispositif de surveillance du VIH et des…
View article: CUIDADOS PRÉ-NATAIS:IMPORTÂNCIA E BENEFICIOS DA FISIOTERAPIA PARA A SAÚDE DA MÃE E DO BEBÊ
CUIDADOS PRÉ-NATAIS:IMPORTÂNCIA E BENEFICIOS DA FISIOTERAPIA PARA A SAÚDE DA MÃE E DO BEBÊ Open
A gestação é um período de intensas transformações fisiológicas e emocionais, exigindo atenção integral à saúde da mulher. Nesse contexto, a fisioterapia desempenha papel essencial nos cuidados pré-natais, promovendo bem-estar, prevenindo …
View article: Maternal Use of Integrase Strand Transfer Inhibitors During Pregnancy and Infant Neurodevelopment
Maternal Use of Integrase Strand Transfer Inhibitors During Pregnancy and Infant Neurodevelopment Open
Importance Current perinatal HIV treatment guidelines recommend inclusion of integrase strand transfer inhibitors (INSTIs), but few studies have evaluated the safety of INSTIs for infant neurodevelopment. Objective To compare the neurodeve…
View article: Understanding the challenges of healthcare transition in the context of HIV-related stigma for young adults with perinatal HIV in Thailand
Understanding the challenges of healthcare transition in the context of HIV-related stigma for young adults with perinatal HIV in Thailand Open
The healthcare transition during adolescence and young adulthood has consistently been reported as a critical period for attrition and adverse health outcomes. The study assessed HIV-related stigma and transition experiences among young pe…
View article: Exploring antiretroviral treatment discontinuation among people living with HIV in Indonesia: A qualitative study
Exploring antiretroviral treatment discontinuation among people living with HIV in Indonesia: A qualitative study Open
Background: Discontinuation of antiretroviral therapy (ART) among people living with HIV (PLHIV) presents significant challenges for HIV care, often leading to physical deterioration, emotional distress, and social isolation. Although prio…
View article: Supplementary Table S2 from Associations of Race and Ethnicity with Hepatocellular Carcinoma, Decompensation, and Mortality in US Veterans with Cirrhosis
Supplementary Table S2 from Associations of Race and Ethnicity with Hepatocellular Carcinoma, Decompensation, and Mortality in US Veterans with Cirrhosis Open
Supplementary Table S2. ICD-9 codes for type 2 diabetes mellitus, alcohol use disorders, hemochromatosis, primary biliary cirrhosis, primary sclerosing cholangitis, autoimmune hepatitis, human immunodeficiency virus, and low socioeconomic …
View article: NEURO-Restore: Convergent Computational and Mathematical Validation of Multi-Target Neuroinflammatory Modulation in Alzheimer's Disease—Independent Pathways to 31-40× Therapeutic Superiority
NEURO-Restore: Convergent Computational and Mathematical Validation of Multi-Target Neuroinflammatory Modulation in Alzheimer's Disease—Independent Pathways to 31-40× Therapeutic Superiority Open
This submission presents NEURO-Restore v3.0, a novel multi-target therapeutic formulation for Alzheimer's disease (AD) with projected 31-40× superiority over current FDA-approved treatments. The work establishes convergent validation throu…
View article: HPV self-sampling for cervical cancer screening among women living with HIV in Ghana: protocol for a hybrid type 1 effectiveness-implementation randomized controlled trial
HPV self-sampling for cervical cancer screening among women living with HIV in Ghana: protocol for a hybrid type 1 effectiveness-implementation randomized controlled trial Open
View article: Harnessing registry data to identify socio-demographic and socio-economic gaps in HIV care in the Netherlands
Harnessing registry data to identify socio-demographic and socio-economic gaps in HIV care in the Netherlands Open
View article: From stigma to self-actualization: The effect of counselling on the mental well-being of people living with HIV/AIDS in Makurdi, Benue State, Nigeria
From stigma to self-actualization: The effect of counselling on the mental well-being of people living with HIV/AIDS in Makurdi, Benue State, Nigeria Open
Human Immunodeficiency Virus and Acquired Immunodeficiency Syndrome (HIV/AIDS) is still considered one of the major world’s health issues. There is still the prevalent psycho-social and emotional effects on people that are constantly livin…
View article: Strengthening implementation science research to improve adolescent and young adult HIV-prevention and care in Sub-Saharan Africa: PATC3H-IN
Strengthening implementation science research to improve adolescent and young adult HIV-prevention and care in Sub-Saharan Africa: PATC3H-IN Open
Background Despite significant progress in HIV prevention and treatment, uptake of evidence-based interventions among adolescents and young adults (AYA), particularly in low- and middle-income countries (LMICs), remains low. Implementation…
View article: Incidence and predictors of mortality among TB-HIV co-infected individuals on anti-tuberculosis and anti-retroviral dual therapy in Northwest Ethiopia: A retrospective cohort study
Incidence and predictors of mortality among TB-HIV co-infected individuals on anti-tuberculosis and anti-retroviral dual therapy in Northwest Ethiopia: A retrospective cohort study Open
Background Co-infection with the human immunodeficiency virus (HIV) and tuberculosis (TB) is a primary cause of death and morbidity. The rate of morbidity and death from TB-HIV is still Ethiopia’s top health issue. Objective This study aim…
View article: Supplementary Table S4-S10 from Circulating Sex Hormone Levels and Risk of Gastrointestinal Cancer: Systematic Review and Meta-Analysis of Prospective Studies
Supplementary Table S4-S10 from Circulating Sex Hormone Levels and Risk of Gastrointestinal Cancer: Systematic Review and Meta-Analysis of Prospective Studies Open
Supplementary Table S4 shows associations with prediagnostic circulating sex hormones levels for esophageal cancer, Supplementary Table S5 for gastric cancer, Supplementary Table S6 for liver cancer, Supplementary Table S7 for pancreatic c…
View article: What medications are recommended to prevent recurrence of HSV-2 viral meningitis?
What medications are recommended to prevent recurrence of HSV-2 viral meningitis? Open
Suppressive antiviral therapy appears to reduce recurrence risk of HSV-2 viral meningitis, with acyclovir, valacyclovir, and famciclovir as options, though clinical effectiveness varies and may require regimen adjustments.
View article: THE CASE OF SEVERE COMMUNITY-ACQUIRED BILATERAL POLYSEGMENTARY PNEUMONIA COMPLICATED WITH BILATERAL EXUDATIVE PLEURITIS AND EMPYEMA ON THE BACKGROUND OF DRUG ADDICTION IN AN ADOLESCENT PATIENT
THE CASE OF SEVERE COMMUNITY-ACQUIRED BILATERAL POLYSEGMENTARY PNEUMONIA COMPLICATED WITH BILATERAL EXUDATIVE PLEURITIS AND EMPYEMA ON THE BACKGROUND OF DRUG ADDICTION IN AN ADOLESCENT PATIENT Open
Nowadays, about 25-50% of adolescents have experience of illegal narcotics using. Community-acquired pneumonia (CAP) remains one of the most urgent problems in modern pediatrics due to its high prevalence, high risks of complications, and …
View article: Data from Cutaneous β HPVs, Sun Exposure, and Risk of Squamous and Basal Cell Skin Cancers in Australia
Data from Cutaneous β HPVs, Sun Exposure, and Risk of Squamous and Basal Cell Skin Cancers in Australia Open
Background:Sun exposure causes cutaneous squamous (SCC) and basal cell (BCC) carcinomas. Human papillomavirus (HPV) infection might cause SCC.Methods:We examined associations of β and γ HPV infection in skin-swab DNA and serum antibodies w…
View article: Rapid ART Initiation with BIC/FTC/TAF in People Who Inject Drugs in Greece: Results from a Pilot Single-Arm Study of an Integrated Care Model
Rapid ART Initiation with BIC/FTC/TAF in People Who Inject Drugs in Greece: Results from a Pilot Single-Arm Study of an Integrated Care Model Open
People who inject drugs (PWIDs) remain underserved in HIV care. Evidence on rapid antiretroviral therapy (ART) for PWID is limited. We evaluated feasibility, effectiveness, safety, and patient-reported outcomes (PROs) for rapid initiation …
View article: KNOWLEDGE AND PRACTICES TOWARDS PREVENTION OF MOTHER-TO-CHILD TRANSMISSION OF HIV AMONG MARRIED MEN ATTENDING THE ANTIRETROVIRAL CLINIC IN AMINU KANO TEACHING HOSPITAL, KANO, NIGERIA
KNOWLEDGE AND PRACTICES TOWARDS PREVENTION OF MOTHER-TO-CHILD TRANSMISSION OF HIV AMONG MARRIED MEN ATTENDING THE ANTIRETROVIRAL CLINIC IN AMINU KANO TEACHING HOSPITAL, KANO, NIGERIA Open
Background: The Prevention of Mother-to-Child Transmission (PMTCT) of HIV programme was introduced as a comprehensive package of interventions to reduce Mother–to–Child Transmission (MTCT) of HIV. The programme offers an opportunity to ide…
View article: ASCIA Inborn Errors of Immunity Clinical Care Standard
ASCIA Inborn Errors of Immunity Clinical Care Standard Open
Introduction Inborn errors of immunity (IEIs) include primary immunodeficiencies (PID) and are a group of more than 550 potentially serious chronic medical conditions. They are caused by defects in genes that control the immune system and …
View article: Acute kidney and liver injury requiring hemodialysis following cathinone use in a person with HIV
Acute kidney and liver injury requiring hemodialysis following cathinone use in a person with HIV Open
This case highlights that clinicians need to be vigilant about the adverse effects of synthetic cathinones used in the context of chemsex as a possible cause of AKI. To the best of our knowledge, this is the first reported case of AKI cause…
View article: Figure S4 from Building Practical Risk Prediction Models for Nasopharyngeal Carcinoma Screening with Patient Graph Analysis and Machine Learning
Figure S4 from Building Practical Risk Prediction Models for Nasopharyngeal Carcinoma Screening with Patient Graph Analysis and Machine Learning Open
Figure S4: Distribution curve of NPC health factors sorted by connection delta ratio (CDR). CDR cutoff = 0.3. Only some codes are visible on the x-axis. Full spectrum of health factors were listed in Table S3.
View article: LDH to lymphocyte percentage ratio is a novel predictor of in-hospital mortality in PLWH - a retrospective study
LDH to lymphocyte percentage ratio is a novel predictor of in-hospital mortality in PLWH - a retrospective study Open
View article: High risk HPV among HIV positive women with normal and abnormal cervical cytology in Bahir Dar, north west Ethiopia
High risk HPV among HIV positive women with normal and abnormal cervical cytology in Bahir Dar, north west Ethiopia Open
View article: Correlation of T Cell Receptor Excision Circles With CD4 T-Lymphocyte Levels Post Haematopoietic Stem Cell Transplant for Severe Combined Immunodeficiency
Correlation of T Cell Receptor Excision Circles With CD4 T-Lymphocyte Levels Post Haematopoietic Stem Cell Transplant for Severe Combined Immunodeficiency Open
Introduction Newborn screening for severe combined immune deficiency (SCID) has recently been introduced across Australia. Variability exists across sites in terms of the assays and methods used for analysis. This makes comparison of data …