Negative control
View article: Reinvestigate the Effect of Punica granatum Peel Ethanol Extract Against Paracetamol Nephrotoxicity in Rats
Reinvestigate the Effect of Punica granatum Peel Ethanol Extract Against Paracetamol Nephrotoxicity in Rats Open
Background: Paracetamol, also known as acetaminophen, is extensively used for pain relief and as an antipyretic drug. High dose of paracetamol is commonly known to induce hepatotoxicity and nephrotoxicity in humans and experimental animals…
View article: Reinvestigate the Effect of Punica granatum Peel Ethanol Extract Against Paracetamol Nephrotoxicity in Rats
Reinvestigate the Effect of Punica granatum Peel Ethanol Extract Against Paracetamol Nephrotoxicity in Rats Open
Background: Paracetamol, also known as acetaminophen, is extensively used for pain relief and as an antipyretic drug. High dose of paracetamol is commonly known to induce hepatotoxicity and nephrotoxicity in humans and experimental animals…
View article: Gel Ekstrak Daun Sirsak (Annona muricata L.): Formulasi dan Efektivitas terhadap Microsporum canis
Gel Ekstrak Daun Sirsak (Annona muricata L.): Formulasi dan Efektivitas terhadap Microsporum canis Open
Daun sirsak (Annona muricata L.) mengandung senyawa genistein, steroid, dan kumarin yang memiliki potensi sebagai agen antijamur alami terhadap Microsporum canis, patogen penyebab ringworm. Penelitian ini bertujuan untuk memformulasi gel e…
View article: Impact of Timing for In-Ovo Injection of Nano Zinc Oxide and Lactobacillus plantarum on Hatchability and Viability in Ross 308 Broilers
Impact of Timing for In-Ovo Injection of Nano Zinc Oxide and Lactobacillus plantarum on Hatchability and Viability in Ross 308 Broilers Open
The present study aimed to evaluate the effect of injecting hatching eggs with zinc oxide nanoparticles (ZnO NPs) and the probiotic bacterium Lactobacillus plantarum (L. plantarum) at two incubation periods (day 10 and 18 of incubation) on…
View article: PENGARUH EKSTRAK KULIT MANGGIS TERHADAP HISTOLOGI JUMLAH SEL NEKROSIS PULAU LANGERHANS TIKUS PUTIH JANTAN HIPERGLIKEMIK
PENGARUH EKSTRAK KULIT MANGGIS TERHADAP HISTOLOGI JUMLAH SEL NEKROSIS PULAU LANGERHANS TIKUS PUTIH JANTAN HIPERGLIKEMIK Open
Tujuan penelitian untuk menganalisa gambaran histologi jumlah sel nekrosis di pulau Langerhans tikus putih jantan kondisi hiperglikemik yang diberi ekstrak kulit manggis. Kondisi hiperglikemik dapat membentuk spesies oksigen reaktif (ROS)/…
View article: Figure S3 from TRIM50 Inhibits Gastric Cancer Progression by Regulating the Ubiquitination and Nuclear Translocation of JUP
Figure S3 from TRIM50 Inhibits Gastric Cancer Progression by Regulating the Ubiquitination and Nuclear Translocation of JUP Open
Figure S3A: Tumor photograph in the nude mouse subcutaneous xenograft model by implanting TRIM50 overexpressing (TRIM50) versus control empty vector (EV) MKN45 cells (n = 6 mice per group). Scale bar: 1 cm Figure S3B: MKN74 cells were tran…
View article: Aktivitas Antihiperglikemik Ekstrak Daun Mint (Mentha spp.) pada Mencit yang Diinduksi Diabetes Melitus
Aktivitas Antihiperglikemik Ekstrak Daun Mint (Mentha spp.) pada Mencit yang Diinduksi Diabetes Melitus Open
Daun Mentha spp. merupakan jenis tanaman herbal yang memiliki potensi sebagai antidiabetik karena memiliki berbagai senyawa metabolit sekunder, seperti flavonoid, tanin, saponin dan alkaloid. Penelitian ini bertujuan untuk mengetahui efek …
View article: Proliferative Effect of Proanthocyanidins on HGF-1 and HPDLF Cells: An In Vitro Study
Proliferative Effect of Proanthocyanidins on HGF-1 and HPDLF Cells: An In Vitro Study Open
Background and Objectives: The use of proanthocyanidins (PACNs) alongside standard periodontal treatment procedures can improve periodontal and peri-implant tissue healing. The present study aimed to evaluate the effect of different concen…
View article: Histologic evaluation of the effect of St John’s wort (Hypericum perforatum L.) and mineral trioxide aggregate (MTA) in partial pulpotomy treatment applied to molar teeth of rats
Histologic evaluation of the effect of St John’s wort (Hypericum perforatum L.) and mineral trioxide aggregate (MTA) in partial pulpotomy treatment applied to molar teeth of rats Open
SWO was used as an alternative agent to MTA, which we use as the gold standard in partial pulpotomy treatment.
View article: Comparison of Clove Leaf Oil Ointment Dosages on Wound Healing in Wistar Rats
Comparison of Clove Leaf Oil Ointment Dosages on Wound Healing in Wistar Rats Open
In Indonesia, clove (Syzygium aromaticum) has long been utilized both as a culinary spice and as a traditional herbal medicine due to its wide range of biological activities, including antimicrobial, anti-inflammatory, antioxidant, analges…
View article: Evaluasi In Vitro Viabilitas Sel Fibroblas Akibat Penambahan Larutan Binahong pada Kalsium Hidroksida sebagai Bahan Pelindung Pulpa
Evaluasi In Vitro Viabilitas Sel Fibroblas Akibat Penambahan Larutan Binahong pada Kalsium Hidroksida sebagai Bahan Pelindung Pulpa Open
Kalsium hidroksida Ca(OH)₂ merupakan bahan pelindung pulpa dengan efek antibakteri tinggi, namun bahan ini masih memiliki kelemahan yaitu terdapat hambatan ikatan antara kristal hidroksiapatit dan jaringan kolagen. Hal ini menyebabkan terj…
View article: Pengaruh Jus Buah Delima (Punica granatum) sebagai Agen Antioksidan pada Tikus Putih (Rattus norvegicus) yang Diinduksi Larutan Complete Freund’s Adjuvant (CFA) melalui Jalur Penurunan Kadar Malondialdehid (MDA)
Pengaruh Jus Buah Delima (Punica granatum) sebagai Agen Antioksidan pada Tikus Putih (Rattus norvegicus) yang Diinduksi Larutan Complete Freund’s Adjuvant (CFA) melalui Jalur Penurunan Kadar Malondialdehid (MDA) Open
Inflamasi kronis berkontribusi pada berbagai penyakit degeneratif, sehingga diperlukan terapi alternatif berbasis antioksidan alami. Buah delima (Punica granatum) kaya akan polifenol, flavonoid, dan tanin yang memiliki potensi antioksidan …
View article: Formulasi Sediaan Bedak Dingin Ekstrak Etanol Daun Kemangi (Ocimum Basilicum L.) Sebagai Antibakteri
Formulasi Sediaan Bedak Dingin Ekstrak Etanol Daun Kemangi (Ocimum Basilicum L.) Sebagai Antibakteri Open
Ekstrak etanol daun kemangi (Ocimum basilicum L.) diketahui memiliki senyawa fitokimia yang memiliki efek antibakteri. Penggunaan antibiotik untuk pengobatan infeksi dapat memberikan efek samping. Perlunya pengobatan lain, salah satunya be…
View article: Contaminación microbiológica por Staphylococcus aureus en superficies inertes de clínicas odontológicas: evaluación de riesgos y control
Contaminación microbiológica por Staphylococcus aureus en superficies inertes de clínicas odontológicas: evaluación de riesgos y control Open
Introducción: La contaminación microbiana en entornos odontológicos constituye un problema relevante para la salud pública, especialmente por la persistencia de patógenos como Staphylococcus aureus en superficies inertes expuestas a aeroso…
View article: Contaminación microbiológica por Staphylococcus aureus en superficies inertes de clínicas odontológicas: evaluación de riesgos y control
Contaminación microbiológica por Staphylococcus aureus en superficies inertes de clínicas odontológicas: evaluación de riesgos y control Open
Introducción: La contaminación microbiana en entornos odontológicos constituye un problema relevante para la salud pública, especialmente por la persistencia de patógenos como Staphylococcus aureus en superficies inertes expuestas a aeroso…
View article: Development and implementation of a gyrolab-based generic anti-drug antibody assay for antibody-drug conjugates in cynomolgus monkey studies
Development and implementation of a gyrolab-based generic anti-drug antibody assay for antibody-drug conjugates in cynomolgus monkey studies Open
Introduction Non-clinical immunogenicity yields valuable insights into pharmacokinetics, efficacy, and safety. Given the complex nature of ADC therapeutics, early detection of anti-drug antibodies (ADAs) is critical for elucidating exposur…
View article: Gastroprotective effect test of ekor naga leaves extract (Rhaphidophora pinnata (L.f) Schott) on male white rats
Gastroprotective effect test of ekor naga leaves extract (Rhaphidophora pinnata (L.f) Schott) on male white rats Open
Rhaphidophora pinnata leaves are one of the herbal plants that have pharmacological effects. Previous research has shown that ekor naga leaves contain secondary metabolites with tonic pharmacological effects, including the ability to heal …
View article: Perbandingan Efektivitas Ekstrak Kulit Jeruk Berastagi (Citrus Sinensis L.) Dengan Povidone-Iodine 10% Terhadap Penyembuhan Luka Sayat Pada Tikus Berdasarkan Jumlah Kolagen dan Lama Penyembuhan Luka
Perbandingan Efektivitas Ekstrak Kulit Jeruk Berastagi (Citrus Sinensis L.) Dengan Povidone-Iodine 10% Terhadap Penyembuhan Luka Sayat Pada Tikus Berdasarkan Jumlah Kolagen dan Lama Penyembuhan Luka Open
Penyembuhan luka merupakan proses biologis kompleks yang melibatkan pembentukan kolagen. Pemanfaatan bahan alami, seperti kulit jeruk Berastagi yang mengandung flavonoid, tanin, dan saponin, berpotensi mempercepat penyembuhan melalui efek …
View article: XU Jin1,2, LI Ke1,2, ZHANG Xiaoxia3, MA Junbai1, WANG Hao1 1. School of Basic Medical Sciences, Ningxia Medical University, Yinchuan 750004,China; 2. Ningxia Hui Autonomous Region People's Hospital, Yinchuan 750002; 3.College of Traditional Chinese Medicine, Ningxia Medical University, Yinchuan 750004, China.
XU Jin1,2, LI Ke1,2, ZHANG Xiaoxia3, MA Junbai1, WANG Hao1 1. School of Basic Medical Sciences, Ningxia Medical University, Yinchuan 750004,China; 2. Ningxia Hui Autonomous Region People's Hospital, Yinchuan 750002; 3.College of Traditional Chinese Medicine, Ningxia Medical University, Yinchuan 750004, China. Open
This study was designed to analyze the effects of Clostridium sporogenes (C. sporogenes) on myeloid-derived suppressor cells (MDSCs) and inflammatory factors in mice with Graves disease (GD).A GD mice model was constructed using recombinan…
View article: Efektifitas Pemberian Salep Eco Enzyme untuk Mengobati Combustio Derajat 1 pada Mencit Deuthschland Danken
Efektifitas Pemberian Salep Eco Enzyme untuk Mengobati Combustio Derajat 1 pada Mencit Deuthschland Danken Open
Luka bakar merupakan kerusakan jaringan kulit akibat paparan panas, bahan kimia, tekanan, gesekan, trauma, maupun radiasi yang dapat menimbulkan rasa nyeri serta meningkatkan risiko infeksi. Salah satu alternatif terapi luka yang berpotens…
View article: Protective Effect of Nyctanthes arbortristis Against Cadmium-induced Genotoxicity in Swiss Albino Mice: A Micronucleus Assay Approach
Protective Effect of Nyctanthes arbortristis Against Cadmium-induced Genotoxicity in Swiss Albino Mice: A Micronucleus Assay Approach Open
Aims: The present study aimed to evaluate the genotoxic effects of cadmium chloride (CdCl₂) and the protective efficacy of Nyctanthes arbortristis using the micronucleus assay in Swiss albino mice. Study Design: An experimental, controlled…
View article: Efek Antihiperglikemik Formula Daun Sirih Cina dan Jahe Merah: Studi Eksperimental pada Tikus Obesitas
Efek Antihiperglikemik Formula Daun Sirih Cina dan Jahe Merah: Studi Eksperimental pada Tikus Obesitas Open
The prevalence of obesity continues to rise annually. According to the 2023 Indonesian Health Survey (SKI), the prevalence increased from 21.8% in 2018 to 23.4% in 2023. Obesity can lead to insulin resistance and elevated blood glucose lev…
View article: Looking for Greener Pastures: In Vitro Screening of Phytogenics for the Control of <i>Sparicotyle chrysophrii</i> in Gilthead Sea Bream
Looking for Greener Pastures: In Vitro Screening of Phytogenics for the Control of <i>Sparicotyle chrysophrii</i> in Gilthead Sea Bream Open
The gill parasite Sparicotyle chrysophrii poses a significant threat to gilthead sea bream ( Sparus aurata ) aquaculture in the Mediterranean, causing considerable mortality and economic losses. As traditional chemotherapeutic treatments, …
View article: Development of a Blocking ELISA for Detection of Serum Neutralizing Antibodies Against Duck Adenovirus Type 3
Development of a Blocking ELISA for Detection of Serum Neutralizing Antibodies Against Duck Adenovirus Type 3 Open
In 2014, Duck Adenovirus type 3 (DAdV-3) emerged in Muscovy ducks and has since spread rapidly across China, causing significant economic losses to the duck industry. Given this situation, the development of reliable diagnostic tools is cr…
View article: Optimization of Nanogel Formulation of Piper Nigrum And Erythrina Subumbrans Extract As Anti-Inflammatory Based On Lontar Usadha Tiwang: Effectiveness Test On Mus Musculus
Optimization of Nanogel Formulation of Piper Nigrum And Erythrina Subumbrans Extract As Anti-Inflammatory Based On Lontar Usadha Tiwang: Effectiveness Test On Mus Musculus Open
Public health in Bali has long been supported by traditional medicine based on local wisdom, one of which is usadha tiwang. In practice, usadha tiwang uses black pepper (Piper nigrum) and dadap leaves (Erythrina subumbrans) to treat mokan …
View article: SEQUESTRATION OF ERYTHROCYTE INFECTED BY Plasmodium berghei ANKA IN MICE LIVER TREATED WITH ETHANOL EXTRACT OF PEARL GRASS (Hedyotis corymbosa (L.) Lamk)
SEQUESTRATION OF ERYTHROCYTE INFECTED BY Plasmodium berghei ANKA IN MICE LIVER TREATED WITH ETHANOL EXTRACT OF PEARL GRASS (Hedyotis corymbosa (L.) Lamk) Open
Background: Malaria is a parasitic infection caused by the Plasmodium genus. Certain Plasmodium species can evade the immune system by sequestering internal organs, including the liver. The ethanolic extract of pearl grass (Hedyotis corymb…
View article: Functional Algal Feeds for Aquaculture: Micro- and Macroalgae Promote Gut Recovery in Gilthead Seabream
Functional Algal Feeds for Aquaculture: Micro- and Macroalgae Promote Gut Recovery in Gilthead Seabream Open
Gut health is essential for optimal growth, immune function, and robustness in aquaculture. This study evaluated the potential of dietary supplementation with micro- and macroalgae to promote intestinal recovery following an insult. Four e…
View article: Effect of postbiotics on the production parameters of rearing goose
Effect of postbiotics on the production parameters of rearing goose Open
Our aim was to measure the mortality, live body weight, feed conversion, intake and detect the weight and stiffness of the liver, liver colour, breast and thigh weight as an effect of the dry form of Burain® postbiotic supplementation in r…
View article: Field evaluation of ethnomedicinal plants’ smoke knockdown and repellent efficacy against pre-bedtime biting malaria vectors in Mazowe district, Zimbabwe
Field evaluation of ethnomedicinal plants’ smoke knockdown and repellent efficacy against pre-bedtime biting malaria vectors in Mazowe district, Zimbabwe Open
The study investigated the knockdown and repellent efficacy of smoke from native plants, Vitex payos (Lour.) Merr., Peltophorum africanum Sond., and Adansonia digitata L., against malaria vectors in Bare ward, Mazowe district, Zimbabwe. Th…
View article: EXPERIMENTAL EVALUATION OF THE ANTI-INFLAMMATORY ACTIVITY OF POLYSACCHARIDES FROM IMMATURE FRUITS OF CAPPARIS SPINOSA L. IN A FORMALININDUCED ASEPTIC ARTHRITIS MODEL
EXPERIMENTAL EVALUATION OF THE ANTI-INFLAMMATORY ACTIVITY OF POLYSACCHARIDES FROM IMMATURE FRUITS OF CAPPARIS SPINOSA L. IN A FORMALININDUCED ASEPTIC ARTHRITIS MODEL Open
This scientific article investigates the anti-inflammatory activity of polysaccharides derived from the immature fruits of Capparis spinosa L. using an experimental animal model. The experiments were conducted on a model of formalin-induce…