Explanipedia

Asymmetric synthesis of stereogenic-at-sulfur compounds via biocatalytic oxidation with Unspecific Peroxygenases Open

Jiacheng Li, Benjamin Melling, Katy A. S. Cornish, Nicholas Mulholland, Jared Cartwright , et al. · 2025

Stereogenic-at-sulfur compounds are vitally important biologically active small molecules, with many drugs featuring chiral sulfur atoms. Methods for the asymmetric synthesis of sulfoxide centres are well established, but methods that prod…

Helical Dispiroindeno[2,1‑c]fluorenes Possessing Planar Chirality: Synthesis and ChiropticalProperties Open

Marko Bogomolec (22826312), Lucia Feriancová (22826315), Jhon Sebastian Oviedo Ortiz (22826318), Jeanne Crassous (1467454), Ivana Císařová (1580947) , et al. · 2025

Syntheses of enantioenriched helical dispiroindeno[2,1-c]fluorenes (DSIF) possessing one or two pCp moieties are presented. These are based on the conversion of (S_p)- and (R_p) pCp-carbaldehydes …

Design of Phosphine-HeteroarenesulfonamideLigandsas Dinuclear Silver Catalysts for Enantioselective Construction ofα,β-Diamino Acids Open

Yuka Iizuka (20403685), Sayuri Okajima (22826492), Yamato Ueno (20395847), Tsunayoshi Takehara (6078332), Takeyuki Suzuki (53775) , et al. · 2025

We designed and developed a phosphine–heteroarenesulfonamide ligand and found that it functions as a chiral dinuclear silver catalyst capable of cooperatively activating both nucleophiles and electrophiles. As a result, a highly enantiosel…

Results of Optically Stimulated Luminescence (OSL) dating. Open

Darren Curnoe (177614), Mohammed S. Sauffi (5345867), Hsiao Mei Goh (22822135), Xue-feng Sun (840166), Roshan Peiris (16546659) · 2025

Results of Optically Stimulated Luminescence (OSL) dating.

Iridium-Catalyzed EnantioselectiveC(sp3)–H Borylation of Bicyclo[1.1.0]butanes Open

Tianmeng Jia (22788304), Lili Chen (66681), Wei Sun (93580), Senmiao Xu (1333545) · 2025

Bicyclo[1.1.0]butanes (BCBs) have attracted considerable interest in organic synthesis due to their versatile reactivity. However, the asymmetric synthesis of these strained systems remains a formidable challenge. We herein report an iridi…

EnantioselectiveSynthesis of Boron-Stereogenic HeterocyclesEnabled by Asymmetric Nickel Catalysis Open

Bin Ma (219839), Xinyue Tang (10697174), Xin Zhou (54275), Dekun Meng (22804585), Anqi Feng (7854116) , et al. · 2025

Despite the widespread utilization of organoboron compounds across various areas, the efficient construction of stable and enantioenriched boron-centered chiral molecules remains a persistent challenge. Here, we present a nickel-catalyzed …

Organoiodine-CatalyzedDesymmetric Fluorolactonizationof α,α-Diallylcarboxylic Acids to Access α‑QuaternaryFluorinated Lactones Open

Jian Chen (15340), Jiaying Li (3250335), Xiang Li (114679) · 2025

The discovery of convenient and efficient methodologies for preparing optically active organofluorine compounds has received much attention from the synthetic community. Herein, we report an organoiodine-catalyzed desymmetric fluorolactoni…

Interaction summary of catechin with the 51KQ active site. Open

Erdi Can Aytar (21491685), Emine Incilay Torunoğlu (22755782), Abidin Gümrükçüoğlu (22016085), Saleh Al-Farraj (17294913), Alper Durmaz (22755785) , et al. · 2025

Interaction summary of catechin with the 51KQ active site.

Optically Active Micellar‐Cubic Liquid Crystals from Quasi‐Racemic Octahedral Metallomesogens Open

Shiho Akiba, Kozue Nishimoto, Hidetaka Yuge, Hisako Sato, Go Watanabe , et al. · 2025

Data from: Organocatalytic enantioselective addition of 3-aryloxindoles to ethenesulfonyl fluoride Open

Blay Gonzalo, Castilla-Mocholí, Alvaro, Montesinos-Magraner, Marc, Fernández-Yagüe, Iñaki, Sanz-Marco, Amparo , et al. · 2025

We report the synthesis of chiral sulfonyl fluorides bearing a carbon quaternary stereocenter. A commercially available organocatalyst (DHQD)2AQN enables the enantioselective addition of 3-substituted oxindoles to ethenesulfonyl fluoride (…

Data from: Organocatalytic enantioselective addition of 3-aryloxindoles to ethenesulfonyl fluoride Open

Blay Gonzalo, Castilla-Mocholí, Alvaro, Montesinos-Magraner, Marc, Fernández-Yagüe, Iñaki, Sanz-Marco, Amparo , et al. · 2025

We report the synthesis of chiral sulfonyl fluorides bearing a carbon quaternary stereocenter. A commercially available organocatalyst (DHQD)2AQN enables the enantioselective addition of 3-substituted oxindoles to ethenesulfonyl fluoride (…

Wavelength-dependent cross section for optically stimulated luminescence in Y SiO5:Ce Open

Jacob C. Warming, Peter Balling, Rosana M. Turtos · 2025

Chiral Bifunctional Photocatalysts with Aromatic Ketones as Photosensitizers Open

Giuseppe Zuccarello · 2025

Because the biological activity of a molecule is directly linked to its three-dimensional configuration, the preparation of chiral compounds is a central discipline in synthetic organic chemistry. With the exploitation of photoredox cataly…

Triple-helical aggregates of copper( i ) cyclic trinuclear complexes for circularly polarized luminescence Open

Guo-Quan Huang, Hu Yang, Ri-Qin Xia, Kun Wu, Yong-Liang Huang , et al. · 2025

Self-assembly of Cu( i ) complexes via enantiomeric helical stacking produces homochiral triple-helical aggregates, enabling a record high luminescence dissymmetry factor (| g lum | > 1 × 10 −2 ) for coinage metal complexes in the red-NIR …

Helically oriented polymer thin films by polarized UV-assisted vapor deposition polymerization Open

Seika Murashita, Hiroki Minakuchi, Yan Tan, Ryosuke Matsubara, Atsushi Kubono · 2025

Helically oriented polymer thin films were prepared by polarized UV-assisted vapor deposition polymerization of achiral polyazomethine. Stepwise modulation of the UV polarization axis during deposition induced chiral ordering, as confirmed…

Halogenated Alkoxythiophene Additives Enhance the Performance of Organic Photodetectors Open

Pengyan Zhang, Xue Jiang, Zheng Gao, Peihao Huang, Lei Liu , et al. · 2025

Morphological optimization of the active layer is pivotal for achieving high‐performance organic photodetectors (OPDs). Capitalizing on the simplicity and efficacy of additive strategies, a series of halogenated alkoxythiophene derivatives…

Double Lateral Flow Test System for Simultaneous Immunodetection of Enantiomeric Forms of Antibiotics: An Ofloxacin Case Study Open

Olga D. Hendrickson, Nadezhda A. Byzova, Anatoly V. ZHERDEV, Boris B. Dzantiev · 2025

Antibiotic stereoisomers as components of medicines are typically characterized by different biological activities. Because pharmaceuticals can include a racemic mixture of stereoisomers, monitoring of all forms is required. One contaminan…

Chiral SURMOFs for Vibrational Circular Dichroism: Multiscale Modeling and Experimental Insights Open

Ana C. Fingolo, Nadine von Coelln, Benedikt Zerulla, Marjan Krstić, Christian Huck , et al. · 2025

Chiral surface‐anchored metal‐organic frameworks (SURMOFs) are emerging as versatile platforms for enantioselective separation, sensing, and the manipulation of circularly polarized light. To harness their full potential, predictive modeli…

Organocatalytic Enantioselective Addition of 3-Aryloxindoles to Ethenesulfonyl Fluoride Open

Álvaro Castilla-Mocholí, Marc Montesinos-Magraner, Iñaki Fernández-Yagüe, Amparo Sanz Marco, Carlos Vila , et al. · 2025

We report the synthesis of chiral sulfonyl fluorides bearing a carbon quaternary stereocenter. A commercially available organocatalyst (DHQD)₂AQN enables the enantioselective addition of 3-substituted oxindoles to ethenesulfonyl…

OrganocatalyticEnantioselective Addition of 3‑Aryloxindolesto Ethenesulfonyl Fluoride Open

Álvaro Castilla-Mocholí (22653392), Marc Montesinos-Magraner (2569852), Iñaki Fernández-Yagüe (22653395), Amparo Sanz-Marco (1325151), Carlos Vila (1696018) , et al. · 2025

We report the synthesis of chiral sulfonyl fluorides bearing a carbon quaternary stereocenter. A commercially available organocatalyst (DHQD)₂AQN enables the enantioselective addition of 3-substituted oxindoles to ethenesulfonyl…

Chiral Bisammonium-DirectedLiving Crystallization-DrivenSelf-Assembly Toward the Preparation of Nanostructures with ControlledDimensions and Tunable Chiroptical Properties Open

Bo Xiang (385481), Hongluo Wu (22647766), Longgang Xia (21648997), Xiaoyu Huang (24573), Guolin Lu (1719541) , et al. · 2025

Polymer nanostructures with controlled morphology and tunable chiroptical activities of circular dichroism (CD) and circularly polarized luminescence (CPL), showing promising applications ranging from information encryption to display, hav…

Ultra-rapid, pressureless, and optically instrumented manufacturing of high-performance ceramics Open

Thomas Grippi, Andrii L. Maximenko, Elisa Torresani, EUGENE A. OLEVSKY · 2025

Chiral Borane-CatalyzedAsymmetric Hydrosilylationof 2,3,3-Trisubstituted 3H‑Indoles Open

Fuqu Zou (20788773), Xiangqing Feng (2073784), Haifeng Du (1420057) · 2025

An asymmetric Piers-type hydrosilylation of 2,3,3-trisubstituted 3H-indoles has been achieved for the first time using a chiral borane catalyst derived by the in situ hydroboration of a chiral monoalkene with HB(C₆F_5…

Synthesis of Bulky α-Cationic Phosphines and Their Applications in π-Acid Catalysis Open

Kentaro Sakamaki, Kyosuke Suzuki, Takuma Nomura, Ryoto Tsuruoka, Shintaro Takai , et al. · 2025

We have developed a synthetic method for triazolium-based bulky α-cationic phosphines. The influence of the steric properties of these cationic phosphines on the catalytic activity in the platinum-catalyzed hydroarylation of propargyl ethe…

Stereoselective Pudovik reaction of aldehydes, aldimines, and nitroalkenes with CAMDOL-derived H-phosphonate Open

Ning Li, Qian Wu, Yu Huang, Li Pan, Junchen Li , et al. · 2025

Superimposed structures of synthesized derivatives (3a − e) in active site of 4N1U. Open

Moeid Goudarzi Karim (22614781), Morteza Mehrdad (16730325), Davood Gheidari (16730322), Nazanin Zahra Gheidari (22614784) · 2025

Superimposed structures of synthesized derivatives (3a − e) in active site of 4N1U.

Bienzymatic Dynamic Kinetic Resolution of Secondary Alcohols by Esterification/Racemization in Water Open

Borowiecki, Paweł, Rudzka, Aleksandra · 2025

The deposited dataset includes: (i) free induction decay (FID) files, acquisition data, and processing parameters for the recorded ¹H, ¹³C, and ¹⁹F NMR spectra for a set of compounds [(hetero)aryl-alk…

N-Heterocyclic Carbene-Catalyzed Enantioselective Synthesis of Inherently Chiral Pillar[5]arenes Open

Xin-Ping Hui, Yinsheng Qi, Xuange Cui, Xiyu Li, Jianwei Cheng · 2025

The catalytic enantioselective synthesis of inherently chiral pillar[5]arene derivatives holds significant promise in materials science, chemical biology, and host-guest chemistry, which is attributable to their unique pillar-shaped archit…

Circling crystal in chiral active matter with self-alignment Open

Musacchio, Marco, Antonov Alexander, Löwen, Hartmut, Caprini, Lorenzo · 2025

The uploaded data are in text format and correspond to the position, active force, velocity, and orientation of the particles.

Data from: Organocatalytic enantioselective addition of 3-aryloxindoles to ethenesulfonyl fluoride Open

Blay Gonzalo, Castilla-Mocholí, Alvaro, Montesinos-Magraner, Marc, Fernández-Yagüe, Iñaki, Sanz-Marco, Amparo , et al. · 2025

We report the synthesis of chiral sulfonyl fluorides bearing a carbon quaternary stereocenter. A commercially available organocatalyst (DHQD)2AQN enables the enantioselective addition of 3-substituted oxindoles to ethenesulfonyl fluoride (…

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