Spectral imaging
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Shortwave infrared fluorescence imaging with the clinically approved near-infrared dye indocyanine green Open
Significance Imaging in the shortwave IR (SWIR) spectral window allows the observation of processes deep within living animals. Recent studies have shown that SWIR imaging enables unprecedented imaging opportunities, including contact-free…
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Molecular imaging of biological systems with a clickable dye in the broad 800- to 1,700-nm near-infrared window Open
Significance Fluorescence-based optical imaging is an important tool allowing researchers and clinicians to molecularly probe wide-ranging biological structures and processes. To break through the traditional molecular imaging window spann…
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Detector-based spectral CT with a novel dual-layer technology: principles and applications Open
Detector-based spectral computed tomography is a novel dual-energy CT technology that employs two layers of detectors to simultaneously collect low- and high-energy data in all patients using standard CT protocols. In addition to the conve…
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Spectral imaging with deep learning Open
The goal of spectral imaging is to capture the spectral signature of a target. Traditional scanning method for spectral imaging suffers from large system volume and low image acquisition speed for large scenes. In contrast, computational s…
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In-Vivo and Ex-Vivo Tissue Analysis through Hyperspectral Imaging Techniques: Revealing the Invisible Features of Cancer Open
In contrast to conventional optical imaging modalities, hyperspectral imaging (HSI) is able to capture much more information from a certain scene, both within and beyond the visual spectral range (from 400 to 700 nm). This imaging modality…
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1000 fps computational ghost imaging using LED-based structured illumination Open
Single-pixel imaging uses a single-pixel detector, rather than a focal plane detector array, to image a scene. It provides advantages for applications such as multi-wavelength, three-dimensional imaging. However, low frame rates have been …
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Spectral CT imaging: Technical principles of dual-energy CT and multi-energy photon-counting CT Open
Spectral computed tomography (CT) imaging encompasses a unique generation of CT systems based on a simple principle that makes use of the energy-dependent information present in CT images. Over the past two decades this principle has been …
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Spectral DiffuserCam: lensless snapshot hyperspectral imaging with a spectral filter array Open
Hyperspectral imaging is useful for applications ranging from medical diagnostics to agricultural crop monitoring; however, traditional scanning hyperspectral imagers are prohibitively slow and expensive for widespread adoption. Snapshot t…
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Simultaneous spatial, spectral, and 3D compressive imaging via efficient Fourier single-pixel measurements Open
Single-pixel imaging can capture images using a detector without spatial resolution, which enables imaging in various situations that are challenging or impossible with conventional pixelated detectors. Here we report a compressive single-…
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Photoacoustic imaging in the second near-infrared window: a review Open
Photoacoustic (PA) imaging is an emerging medical imaging modality that combines optical excitation and ultrasound detection. Because ultrasound scatters much less than light in biological tissues, PA generates high-resolution images at ce…
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Advancing biomedical imaging Open
Imaging reveals complex structures and dynamic interactive processes, located deep inside the body, that are otherwise difficult to decipher. Numerous imaging modalities harness every last inch of the energy spectrum. Clinical modalities i…
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Compact snapshot hyperspectral imaging with diffracted rotation Open
Traditional snapshot hyperspectral imaging systems include various optical elements: a dispersive optical element (prism), a coded aperture, several relay lenses, and an imaging lens, resulting in an impractically large form factor. We see…
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Spectral tomographic imaging with aplanatic metalens Open
Tomography is an informative imaging modality that is usually implemented by mechanical scanning, owing to the limited depth-of-field (DOF) in conventional systems. However, recent imaging systems are working towards more compact and stabl…
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Rapid Sequential in Situ Multiplexing with DNA Exchange Imaging in Neuronal Cells and Tissues Open
To decipher the molecular mechanisms of biological function, it is critical to map the molecular composition of individual cells or even more importantly tissue samples in the context of their biological environment in situ. Immunofluoresc…
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Snapshot spectral imaging with parallel metasystems Open
An array of cascaded metasurfaces implements a compact and lightweight spectral imager that acquires real-time videos.
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Non-destructive drug inspection in covering materials using a terahertz spectral imaging system with injection-seeded terahertz parametric generation and detection Open
In 2003, we reported the first-ever development of a spectral imaging system for illicit drugs detection using a terahertz (THz) wave parametric oscillator (TPO) [K. Kawase et al., Opt. Exp. 11(20), 2549 2003]. The system has a dynamic ran…
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Ultraspectral Imaging Based on Metasurfaces with Freeform Shaped Meta‐Atoms Open
Metasurfaces have an exceptional capacity to manipulate the phase, amplitude, polarization, or spectrum of light. However, unit cells, or meta‐atoms, of metasurfaces are conventionally designed using regular shapes, limiting performance im…
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Three-dimensional nanoscale molecular imaging by extreme ultraviolet laser ablation mass spectrometry Open
Analytical probes capable of mapping molecular composition at the nanoscale are of critical importance to materials research, biology and medicine. Mass spectral imaging makes it possible to visualize the spatial organization of multiple m…
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Molecular imaging probes for multi-spectral optoacoustic tomography Open
In this review, we discuss recent progress in emerging optoacoustic probes, their mechanisms, applications and challenges for biological imaging using MSOT.
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Deeply learned broadband encoding stochastic hyperspectral imaging Open
Many applications requiring both spectral and spatial information at high resolution benefit from spectral imaging. Although different technical methods have been developed and commercially available, computational spectral cameras represe…
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Hyper-Spectral Imaging Technique in the Cultural Heritage Field: New Possible Scenarios Open
Imaging spectroscopy technique was introduced in the cultural heritage field in the 1990s, when a multi-spectral imaging system based on a Vidicon camera was used to identify and map pigments in paintings. Since then, with continuous impro…
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Visible and infrared imaging spectroscopy of paintings and improved reflectography Open
Background Imaging spectroscopy, the collection of spatially co-registered images in many contiguous spectral bands, has been developed for remote sensing of the Earth utilizing reflectance or luminescence. In this paper we summarize findi…
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Proximal Methods for Plant Stress Detection Using Optical Sensors and Machine Learning Open
Plant stresses have been monitored using the imaging or spectrometry of plant leaves in the visible (red-green-blue or RGB), near-infrared (NIR), infrared (IR), and ultraviolet (UV) wavebands, often augmented by fluorescence imaging or flu…
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Spectrometer-free vibrational imaging by retrieving stimulated Raman signal from highly scattered photons Open
Vibrational imaging reveals vitamin E distribution on mouse skin in vivo and captures human breast cancer tissues in situ.
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Mantis shrimp–inspired organic photodetector for simultaneous hyperspectral and polarimetric imaging Open
Semitransparent polarization-sensitive organic detectors reveal unprecedented degrees of freedom for multidimensional imaging.
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Miniature Compressive Ultra-spectral Imaging System Utilizing a Single Liquid Crystal Phase Retarder Open
Spectroscopic imaging has been proved to be an effective tool for many applications in a variety of fields, such as biology, medicine, agriculture, remote sensing and industrial process inspection. However, due to the demand for high spect…
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Sequentially timed all-optical mapping photography (STAMP) utilizing spectral filtering Open
We propose and experimentally demonstrate a new method called SF-STAMP for sequentially timed all-optical mapping photography (STAMP) that utilizes spectral filtering. SF-STAMP is composed of a diffractive optical element (DOE), a band-pas…
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Universal Super‐Resolution Multiplexing by DNA Exchange Open
Super‐resolution microscopy allows optical imaging below the classical diffraction limit of light with currently up to 20× higher spatial resolution. However, the detection of multiple targets (multiplexing) is still hard to implement and …
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Spectral-temporal compressive imaging Open
This Letter presents a compressive camera that integrates mechanical translation and spectral dispersion to compress a multi-spectral, high-speed scene onto a monochrome, video-rate detector. Experimental reconstructions of 17 spectral cha…
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Myocardial Late Iodine Enhancement and Extracellular Volume Quantification with Dual-Layer Spectral Detector Dual-Energy Cardiac CT Open
Dual-energy cardiac CT can assess myocardial LIE and quantify ECV, with results comparable to those obtained by using cardiac MRI.© RSNA, 2019See also the commentary by Litt in this issue.