Circulatory system
View article: Echo-167: Direct Optical Detection of Substrate Decoupling Events During Clinical Death and Resuscitation
Echo-167: Direct Optical Detection of Substrate Decoupling Events During Clinical Death and Resuscitation Open
Announcement of Echo-167: the first experiment to continuously measure predicted ghost-perturbation wavefronts during human circulatory arrest using the Swygert 167× laser interferometer (phase sensitivity 1.67 × 10⁻²¹ rad/√Hz). Recording …
View article: Echo-167: Direct Optical Detection of Substrate Decoupling Events During Clinical Death and Resuscitation
Echo-167: Direct Optical Detection of Substrate Decoupling Events During Clinical Death and Resuscitation Open
Announcement of Echo-167: the first experiment to continuously measure predicted ghost-perturbation wavefronts during human circulatory arrest using the Swygert 167× laser interferometer (phase sensitivity 1.67 × 10⁻²¹ rad/√Hz). Recording …
View article: What are the mechanisms of action of cerebral small vessel disease?
What are the mechanisms of action of cerebral small vessel disease? Open
Cerebral small vessel disease involves complex mechanisms such as endothelial dysfunction, immune system involvement, structural vascular changes, and blood-brain barrier compromise, contributing to its pathophysiology.
View article: What is the role of the vasodilator arm of the renin-angiotensin system in maintaining cardiovascular health?
What is the role of the vasodilator arm of the renin-angiotensin system in maintaining cardiovascular health? Open
The vasodilator arm of the renin-angiotensin system, primarily involving ACE2 and angiotensin-(1–7), is crucial for maintaining cardiovascular health by offsetting the vasoconstrictive effects of angiotensin II and promoting vascular prote…
View article: What are the mechanisms of action of cerebral small vessel disease?
What are the mechanisms of action of cerebral small vessel disease? Open
Cerebral small vessel disease involves complex mechanisms such as endothelial dysfunction, immune system involvement, structural vascular changes, and blood-brain barrier compromise, contributing to its pathophysiology.
View article: Initial Polish single-center experience with Impella 5.0/5.5 in cardiogenic shock
Initial Polish single-center experience with Impella 5.0/5.5 in cardiogenic shock Open
View article: Exploring physiological factors underlying individual differences in exercise‐induced blood pressure responses
Exploring physiological factors underlying individual differences in exercise‐induced blood pressure responses Open
Even among healthy individuals, arterial blood pressure (ABP) responses to exercise vary widely. However, the mechanisms underlying this individual variability remain unclear. To investigate these mechanisms, 29 participants performed isom…
View article: ECMO-Assisted In-Situ Normothermic Perfusion for Donation After Circulatory Determination of Death Kidney Transplantation: A Narrative Review
ECMO-Assisted In-Situ Normothermic Perfusion for Donation After Circulatory Determination of Death Kidney Transplantation: A Narrative Review Open
View article: Relevance of Clonal Hematopoiesis in Immune Cells for Degenerative Aortic Valve Stenosis
Relevance of Clonal Hematopoiesis in Immune Cells for Degenerative Aortic Valve Stenosis Open
Clonal hematopoiesis of indeterminate potential (CHIP), defined as the presence of somatic mutations in subjects without other hematologic abnormalities has been recently associated with several cardiovascular diseases. Degenerative aortic…
View article: Circadian Control of Neutrophils Drives Collateral Perfusion and Stroke Outcome
Circadian Control of Neutrophils Drives Collateral Perfusion and Stroke Outcome Open
BACKGROUND: Stroke remains a leading cause of mortality and disability, driven by complex, time-dependent mechanisms that aggravate ischemic injury. Collateral perfusion dictates infarct size, expansion rate, and penumbral preservation, ye…
View article: Complement proteins associated with circulatory and glomerular IgA-containing immune complexes in patients with IgA nephropathy
Complement proteins associated with circulatory and glomerular IgA-containing immune complexes in patients with IgA nephropathy Open
View article: Mechanical circulatory support above a mechanical aortic valve during protected high-risk coronary intervention: a case report
Mechanical circulatory support above a mechanical aortic valve during protected high-risk coronary intervention: a case report Open
View article: Central arterial stiffness, flow-mediated dilation and venous function in postural orthostatic tachycardia syndrome (POTS)
Central arterial stiffness, flow-mediated dilation and venous function in postural orthostatic tachycardia syndrome (POTS) Open
Postural Orthostatic Tachycardia Syndrome (POTS) is a debilitating disorder characterised by excessive increases in heart rate upon standing and poor orthostatic tolerance. Impairments in large artery, endothelial, and venous function may …
View article: Human Plasma in Calcific Aortic Valve Disease: Not Simply a Depot of Biomarkers
Human Plasma in Calcific Aortic Valve Disease: Not Simply a Depot of Biomarkers Open
View article: Spontaneous left anterior descending artery dissection as a cause of myocardial infarction with non-obstructive coronary arteries in a young woman
Spontaneous left anterior descending artery dissection as a cause of myocardial infarction with non-obstructive coronary arteries in a young woman Open
View article: Yixintai treats chronic heart failure in rats by regulating gut microbiota and bile acid
Yixintai treats chronic heart failure in rats by regulating gut microbiota and bile acid Open
Introduction Yixintai (YXT) medicine for chronic heart failure (CHF), has demonstrated safety and efficacy in the treatment of CHF. However, its precise mechanistic actions require further elucidation. Methods This study identified compone…
View article: What is the role of the vasodilator arm of the renin-angiotensin system in maintaining cardiovascular health?
What is the role of the vasodilator arm of the renin-angiotensin system in maintaining cardiovascular health? Open
The vasodilator arm of the renin-angiotensin system, primarily involving ACE2 and angiotensin-(1–7), is crucial for maintaining cardiovascular health by offsetting the vasoconstrictive effects of angiotensin II and promoting vascular prote…
View article: Blood Supply to Legs Point in Indian Neurotherapy: Circulatory Activation for Lower-Limb Strength and Mobility
Blood Supply to Legs Point in Indian Neurotherapy: Circulatory Activation for Lower-Limb Strength and Mobility Open
The Blood Supply to Legs Point in Indian Neurotherapy corresponds to the reflex zones located along the lower back, hips, and upper thigh pathways that influence arterial and venous circulation to the entire lower limb. The highlighted ana…
View article: Cardiac fibrosis induced by high‐fat diet in <scp>ApoE</scp> ‐deficient male mice is exacerbated by genetic deletion of <scp>PACAP</scp> – <scp>PAC1</scp> signaling
Cardiac fibrosis induced by high‐fat diet in <span>ApoE</span> ‐deficient male mice is exacerbated by genetic deletion of <span>PACAP</span> – <span>PAC1</span> signaling Open
Cardiac fibrosis is characterized by an excessive accumulation of extracellular matrix proteins and occurs in a variety of cardiac diseases, such as the highly prevalent syndrome heart failure with preserved ejection fraction (HFpEF) and o…
View article: Innovative efficient approaches to (IV) fluid administration: the role of multiple (IV) lines in enhancing flow rates
Innovative efficient approaches to (IV) fluid administration: the role of multiple (IV) lines in enhancing flow rates Open
Fluid therapy is essential for maintaining circulatory homeostasis and ensuring adequate oxygen delivery to tissues during surgery and certain traumatic conditions. According to Poiseuille’s Law, flow rate is influenced by pressure gradien…
View article: Resting Cerebrovascular Haemodynamics and Dynamic Assessment of Cerebrovascular Function in Polycystic Ovary Syndrome
Resting Cerebrovascular Haemodynamics and Dynamic Assessment of Cerebrovascular Function in Polycystic Ovary Syndrome Open
Objective Despite an increased cerebrovascular disease risk, the impact of Polycystic Ovary Syndrome (PCOS) on cerebrovascular haemodynamics and function is unknown. This study characterised cerebrovascular haemodynamics and function in wo…
View article: ON THE SPINE Points in Indian Neurotherapy: Blood-Supply Enhancement Along the Vertebral Line
ON THE SPINE Points in Indian Neurotherapy: Blood-Supply Enhancement Along the Vertebral Line Open
The On the spine points in Indian Neurotherapy run along the length of the vertebral column and are stimulated to enhance blood circulation, nerve conduction, and muscular relaxation throughout the body. T…
View article: Organ Clear Point in Indian Neurotherapy: Detoxification and Organ Pathway Activation
Organ Clear Point in Indian Neurotherapy: Detoxification and Organ Pathway Activation Open
The Organ Clear Point in Indian Neurotherapy refers to a therapeutic stimulation technique designed to cleanse, unblock, and activate the body’s internal organ pathways. This point targets reflex zones con…
View article: Hypovolemia Evokes Conserved Inverse Neurovascular Coupling in the Supraoptic Nucleus Independent of Heart Failure
Hypovolemia Evokes Conserved Inverse Neurovascular Coupling in the Supraoptic Nucleus Independent of Heart Failure Open
Vasopressin (AVP) neurons in the hypothalamic supraoptic nucleus (SON) are activated by systemic challenges that threaten fluid balance. Beyond their classical activity-dependent release of their neuropeptide cargo into the systemic circul…
View article: Profiling of main regulators of angiogenesis and inflammation in human PBMC and plasma revealed associations with lower extremity artery disease
Profiling of main regulators of angiogenesis and inflammation in human PBMC and plasma revealed associations with lower extremity artery disease Open
Lower extremity artery disease (LEAD) represents the most common atherosclerosis-related disease in the group of peripheral artery diseases. A growing amount of evidence suggests that dysregulations in signaling pathways associated with an…
View article: ON THE SPINE Points in Indian Neurotherapy: Blood-Supply Enhancement Along the Vertebral Line
ON THE SPINE Points in Indian Neurotherapy: Blood-Supply Enhancement Along the Vertebral Line Open
The On the spine points in Indian Neurotherapy run along the length of the vertebral column and are stimulated to enhance blood circulation, nerve conduction, and muscular relaxation throughout the body. These points lie over key autonomic…
View article: Ten ethical challenges in donation after circulatory death (DCD): a practical guide for intensivists
Ten ethical challenges in donation after circulatory death (DCD): a practical guide for intensivists Open
View article: Development of a standardized ovine aortic stenosis model: a pathomimetic platform for TAVI evaluation and durability testing
Development of a standardized ovine aortic stenosis model: a pathomimetic platform for TAVI evaluation and durability testing Open
Background Transcatheter aortic valve implantation (TAVI) has gained widespread clinical acceptance owing to its minimally invasive approach and enhanced postoperative recovery. This study developed a standardized ovine aortic stenosis (AS…
View article: Analysis of Preductal–Postductal Oxygen Saturation Alterations in Pulse Oximetry Screening of Asymptomatic Newborns
Analysis of Preductal–Postductal Oxygen Saturation Alterations in Pulse Oximetry Screening of Asymptomatic Newborns Open
Pulse oximetry screening has become a cornerstone in the early detection of critical congenital heart disease in newborns, offering a non-invasive and accessible method to identify subtle disturbances in oxygenation that may not be clinica…
View article: Effect of Statin Potency on Rapid Coronary Intimal Thickening and Rejection in Heart Transplant Recipients
Effect of Statin Potency on Rapid Coronary Intimal Thickening and Rejection in Heart Transplant Recipients Open