Genetic linkage
View article: Genetic Architecture of Angular Leaf Spot Resistance in Cultivated Strawberry Shaped by Epistasis and Genotype-by-Environment Interactions
Genetic Architecture of Angular Leaf Spot Resistance in Cultivated Strawberry Shaped by Epistasis and Genotype-by-Environment Interactions Open
Angular leaf spot (ALS), caused by Xanthomonas fragariae, is a bacterial disease that limits strawberry (Fragaria ananassa) productivity worldwide. Although major resistance loci have been identified in wild Fragaria species, their introgr…
View article: Genetic Architecture of Angular Leaf Spot Resistance in Cultivated Strawberry Shaped by Epistasis and Genotype-by-Environment Interactions
Genetic Architecture of Angular Leaf Spot Resistance in Cultivated Strawberry Shaped by Epistasis and Genotype-by-Environment Interactions Open
Angular leaf spot (ALS), caused by Xanthomonas fragariae, is a bacterial disease that limits strawberry (Fragaria ananassa) productivity worldwide. Although major resistance loci have been identified in wild Fragaria species, their introgr…
View article: Mapping of quantitative trait locus for resistance to anthracnose in a population derived from genotypes PI 527538 and Ervilha of common bean
Mapping of quantitative trait locus for resistance to anthracnose in a population derived from genotypes PI 527538 and Ervilha of common bean Open
Anthracnose (ANT) caused by the fungus Colletotrichum lindemuthianum is a major disease of common bean ( Phaseolus vulgaris L.). The objectives of this study were to (i) characterize four isolates of C. lindemuthianum into races, (ii) iden…
View article: Shared genetic architecture between anorexia nervosa and metabolomic biomarkers suggest underlying causal pathways
Shared genetic architecture between anorexia nervosa and metabolomic biomarkers suggest underlying causal pathways Open
Background Anorexia Nervosa (AN) has a high mortality rate and often a chronic illness course, yet few existing treatments are effective. AN is heritable and shares genetic architecture with cardiometabolic traits, while the relationship t…
View article: Data Sheet 1_Genetic architecture and genomic prediction of vase life in carnation.pdf
Data Sheet 1_Genetic architecture and genomic prediction of vase life in carnation.pdf Open
Vase life is a key trait for carnation cut flowers. A better understanding of the genetic basis of vase life is needed to implement selection methods like marker-assisted selection or genomic selection. Our objective was to investigate the…
View article: Genetic analysis of <i>NOP56</i> (GGCCTG)n repeat expansions.
Genetic analysis of <i>NOP56</i> (GGCCTG)n repeat expansions. Open
(A) Three unrelated pedigrees with SCA36 characterized in this study. Affected individuals are indicated by filled symbols, and index cases from individual families underwent genetic analysis and further skin biopsy are marked with …
View article: Elevated Soybean Seed Oil Phenotype Associated with a Single Nucleotide Polymorphism in GmNFR1α
Elevated Soybean Seed Oil Phenotype Associated with a Single Nucleotide Polymorphism in GmNFR1α Open
Soybean seed composition, particularly the oil and protein content of the seed, has been a longstanding focus of research due to the economic and nutritional importance of these components for both feed and industrial applications. Through…
View article: Causes of deaths identified in the linkage not classified as maternal deaths.
Causes of deaths identified in the linkage not classified as maternal deaths. Open
Causes of deaths identified in the linkage not classified as maternal deaths.
View article: Nueva variante en gen PLP1 asociada a paraplejia espástica tipo 2, ligada al X: primer reporte de una familia en Colombia
Nueva variante en gen PLP1 asociada a paraplejia espástica tipo 2, ligada al X: primer reporte de una familia en Colombia Open
Hereditary spastic paraplegias (HSP) are genetic disorders characterized by spasticity in the lower limbs, weakness, and sensory disturbances. Global prevalence ranges from 1.27 to 9.6 per 100,000 individuals. Mutations in the PLP1 gene ca…
View article: Table 2_Identification and characterization of QTL for grain protein content derived from the D genome of allohexaploid wheat.docx
Table 2_Identification and characterization of QTL for grain protein content derived from the D genome of allohexaploid wheat.docx Open
Introduction Identifying and utilizing major quantitative trait loci (QTLs) related to wheat grain protein content (GPC) is critical for the wheat quality improvement. However, the identification of genes regulating GPC remains relatively …
View article: Table 1_Identification and characterization of QTL for grain protein content derived from the D genome of allohexaploid wheat.xlsx
Table 1_Identification and characterization of QTL for grain protein content derived from the D genome of allohexaploid wheat.xlsx Open
Introduction Identifying and utilizing major quantitative trait loci (QTLs) related to wheat grain protein content (GPC) is critical for the wheat quality improvement. However, the identification of genes regulating GPC remains relatively …
View article: Regional association plots of genetic associations with urinary zinc levels and colocalization results with gene expression in kidneys.
Regional association plots of genetic associations with urinary zinc levels and colocalization results with gene expression in kidneys. Open
Panel A-B-C: The top plot shows the genetic variants and their associations with urinary zinc levels (negative logarithm of p-values) color-coded based on linkage disequilibrium (LD) with the lead SNP, highlighted in purple. The bot…
View article: Read-level mutation linkage in wastewater sequencing reveals cryptic virus evolution and persistence
Read-level mutation linkage in wastewater sequencing reveals cryptic virus evolution and persistence Open
Wastewater sequencing has become widely adopted as a complement to clinical genomic surveillance, providing population-level monitoring capable of detecting “cryptic variants”, viruses that are rarely, if ever, observed clinically. However…
View article: Read-level mutation linkage in wastewater sequencing reveals cryptic virus evolution and persistence
Read-level mutation linkage in wastewater sequencing reveals cryptic virus evolution and persistence Open
Wastewater sequencing has become widely adopted as a complement to clinical genomic surveillance, providing population-level monitoring capable of detecting “cryptic variants”, viruses that are rarely, if ever, observed clinically. However…
View article: In-silico Characterization of Defence-Related Genes for Blast Resistance on Chromosome 7 in Rice (Oryza sativa L.)
In-silico Characterization of Defence-Related Genes for Blast Resistance on Chromosome 7 in Rice (Oryza sativa L.) Open
Rice blast, caused by Magnaporthe oryzae, remains a major constraint to global rice production. Genetic resistance to blast is a well known phenomenon where hundreds of QTLs or genes have been reported. The in-silico characterization of th…
View article: Genome-wide analysis of Udai21: Unraveling the genetic basis of superior eating quality in rice
Genome-wide analysis of Udai21: Unraveling the genetic basis of superior eating quality in rice Open
Rice ( Oryza sativa L.) is a staple for more than half of the world’s population, and grain quality strongly influences consumer preference and market value. Udai21, also referred to as Ohkome21, and previously designated as Yudai21, is a …
View article: Identification of microbiome-associated loci in super hybrid rice reveals the regulation of OsBRI1 on nitrogen-dependent root microbiome assembly
Identification of microbiome-associated loci in super hybrid rice reveals the regulation of OsBRI1 on nitrogen-dependent root microbiome assembly Open
Using QTL analysis, our study identifies a set of genetic loci that link the root microbiome composition of the hybrid rice LYP9 and reveals that OsBRI1 regulates the assembly of the nitrogen-dependent rice root microbiome.
View article: Genome assembly and predicted gene BUSCO scores.
Genome assembly and predicted gene BUSCO scores. Open
Rice (Oryza sativa L.) is a staple for more than half of the world’s population, and grain quality strongly influences consumer preference and market value. Udai21, also referred to as Ohkome21, and previously designated as Yudai21…
View article: Publisher Correction: Realizing the full potential of Our Future Health through data linkage and trans-biobank efforts
Publisher Correction: Realizing the full potential of Our Future Health through data linkage and trans-biobank efforts Open
View article: Prevalence, Characteristics, and Genetic Architecture of Avoidant/Restrictive Food Intake Phenotypes
Prevalence, Characteristics, and Genetic Architecture of Avoidant/Restrictive Food Intake Phenotypes Open
Importance A narrow range of food consumption and/or restricted eating is a core feature of avoidant/restrictive food intake (ARFI) disorder. However, there is limited knowledge of developmental characteristics of children with ARFI and it…
View article: QTL Mapping and Fine Mapping of a Major Quantitative Trait Locus (qBS11) Conferring Resistance to Rice Brown Spot
QTL Mapping and Fine Mapping of a Major Quantitative Trait Locus (qBS11) Conferring Resistance to Rice Brown Spot Open
Rice brown spot (BS) disease, caused by Bipolaris oryzae, is a significant threat to rice production worldwide. In this study, a major quantitative trait locus (QTL), qBS11, associated with resistance to BS in rice, was identified and fine…
View article: A wheat stripe rust adult plant resistant gene YrJ262 mapping within a spontaneous terminal deletion in the short arm of chromosome 3B
A wheat stripe rust adult plant resistant gene YrJ262 mapping within a spontaneous terminal deletion in the short arm of chromosome 3B Open
Wheat stripe (or yellow) rust, caused by Puccinia striiformis f. sp. tritici , imposes one of the gravest constraints to wheat production. While race-specific seedling resistance genes can be effective in controlling this disease, those wh…
View article: Shared Genetic Links Between Birth Weight and Developmental‐Behavioral Disorders
Shared Genetic Links Between Birth Weight and Developmental‐Behavioral Disorders Open
While observational studies have linked birth weight to developmental‐behavioral disorders, establishing genetic correlations and causal relationships remains challenging due to potential confounding factors. In this study, we assessed gen…
View article: QTL mapping and candidate gene identification of the full flowering date trait in olive trees (Olea Europaea L.)
QTL mapping and candidate gene identification of the full flowering date trait in olive trees (Olea Europaea L.) Open
Future climate models project that increases in global warming will have severe impacts on the flowering phenology of perennial fruit trees, including olive trees, a key species extensively cultivated in the Mediterranean region. Understan…
View article: QTL Mapping of Seed Fatty Acid Contents in Camelina sativa Under Heat Stress
QTL Mapping of Seed Fatty Acid Contents in Camelina sativa Under Heat Stress Open
Heat stress alters oil quality in oilseed crops, yet its genetic underpinnings in Camelina sativa remain unclear. This study investigated the genetic basis of heat-induced changes in seed fatty acids using a recombinant inbred line (RIL) p…
View article: Genetic and Molecular Determinants of Familial Transmission of Skeletal Malocclusions
Genetic and Molecular Determinants of Familial Transmission of Skeletal Malocclusions Open
Families studies conducted in different ethnic populations worldwide have helped elucidate the molecular and genetic factors involved in the development of skeletal class III malocclusion. Therefore, the aim of this study is to provide an …
View article: A multilayered genetic structure analysis between inflammatory bowel disease and bone density/osteoporosis
A multilayered genetic structure analysis between inflammatory bowel disease and bone density/osteoporosis Open
Background The association between inflammatory bowel disease (IBD) and reduced bone mineral density (BMD) or osteoporosis is still a subject of ongoing debate, underscoring the need for further exploration, particularly from a genetic per…
View article: Shared genetic architecture between autism spectrum disorder, loneliness, and social isolation reveals novel genetic loci
Shared genetic architecture between autism spectrum disorder, loneliness, and social isolation reveals novel genetic loci Open
Objective Deficits in social communication and social interaction are core features of autism spectrum disorder (ASD), and studies suggest that loneliness and social isolation are common. ASD has a strong genetic basis, but the genetic arc…
View article: Identification of molecular markers associated with comb traits through genome-wide association study on a specialized strain of yellow feathered broilers
Identification of molecular markers associated with comb traits through genome-wide association study on a specialized strain of yellow feathered broilers Open
It is of great significance to identify candidate genes and molecular markers related to the comb development, in order to accelerate comb breeding progress of yellow feathered broiler. Herein, 400 terminal male chickens of the fast-type y…
View article: Associations between sickle haemoglobin and the <i>Plasmodium falciparum CLAG</i> and <i>FIKK</i> gene families revealed by meta-analysis of 6,289 African samples
Associations between sickle haemoglobin and the <i>Plasmodium falciparum CLAG</i> and <i>FIKK</i> gene families revealed by meta-analysis of 6,289 African samples Open
The recent discovery that mutations in the Plasmodium falciparum genome are overrepresented in infections of sickle haemoglobin (HbS)-carriers has highlighted new questions about the underlying biological and evolutionary interaction, yet …