Bigeminy ≈ Bigeminy
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Nadolol decreases the incidence and severity of ventricular arrhythmias during exercise stress testing compared with β1-selective β-blockers in patients with catecholaminergic polymorphic ventricular tachycardia Open
The incidence and severity of ventricular arrhythmias decreased during treatment with nadolol compared with during treatment with β1-selective β-blockers. β1-Selective β-blockers did not change the occurrence or severity of arrhythmias com…
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Current topics in catecholaminergic polymorphic ventricular tachycardia Open
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is induced by emotions or exercise in patients without organic heart disease and may be polymorphic or bidirectional in nature. The prognosis of CPVT is not good, and therefore p…
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Deep learning for comprehensive ECG annotation Open
The BeatLogic platform represents the next stage of advancement for algorithmic ECG interpretation. This comprehensive platform performs beat detection, beat classification, and rhythm detection/classification with greatly improved perform…
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Electrocardiographic differentiation of idiopathic right ventricular outflow tract ectopy from early arrhythmogenic right ventricular cardiomyopathy Open
In patients with RVOT VEBs and no major electrocardiographic or echocardiographic abnormalities, the ectopic QRS morphology aids in the differential diagnosis between idiopathic RVOT arrhythmias and early ARVC.
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Genetic Loss of <i>I</i> <sub>K1</sub> Causes Adrenergic-Induced Phase 3 Early Afterdepolariz ations and Polymorphic and Bidirectional Ventricular Tachycardia Open
Background: Arrhythmia syndromes associated with KCNJ2 mutations have been described clinically; however, little is known of the underlying arrhythmia mechanism. We create the first patient inspired KCNJ2 transgenic mouse and study effects…
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Quantification of Left Ventricular Function With Premature Ventricular Complexes Reveals Variable Hemodynamics Open
Background— Premature ventricular complexes (PVCs) are prevalent in the general population and are sometimes associated with reduced ventricular function. Current echocardiographic and cardiovascular magnetic resonance imaging techniques d…
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Computational Analysis of Coronary Blood Flow: The Role of Asynchronous Pacing and Arrhythmias Open
In this work we present a one-dimensional (1D) mathematical model of the coronary circulation and use it to study the effects of arrhythmias on coronary blood flow (CBF). Hydrodynamical models are rarely used to study arrhythmias’ effects …
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Eccentric hypertrophy in an animal model of mid- and long-term premature ventricular contraction–induced cardiomyopathy Open
In contrast to bigeminal PACs, PVCs result in a cardiomyopathy characterized by reduced LV ejection fraction, LV dilation, and eccentric hypertrophy that plateaus between 12 and 16 weeks. The lack of remodeling in chronic PACs suggests tha…
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Self-gated MRI of multiple beat morphologies in the presence of arrhythmias Open
Self-gated imaging can reconstruct images during ectopy and allowed for quantification of hemodynamic function of different beat morphologies. Magn Reson Med 78:678-688, 2017. © 2016 International Society for Magnetic Resonance in Medicine.
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Ivabradine for congenital junctional ectopic tachycardia in siblings Open
Sir, Junctional ectopic tachycardia (JET) remains a difficult arrhythmia to manage, and persistent JET in children often results in ventricular dysfunction, heart failure, and high mortality.[12] Familial JET occurs in 20%–40% of cases.[3]…
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Flecainide treats a novel KCNJ2 mutation associated with Andersen-Tawil syndrome Open
KCNJ2 encodes for the potassium inward rectifier channel protein Kir2.1, and mutations in KCNJ2 are associated with various inherited arrhythmia syndromes, such as Andersen-Tawil syndrome type 1 (ATS1), short QT syndrome 3, familial atrial…
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Relationship Between Obstructive Sleep Apnea and Late Gadolinium Enhancement and Their Effect on Cardiac Arrhythmias in Patients with Hypertrophic Obstructive Cardiomyopathy Open
Both OSA and LGE% were associated with a greater likelihood and increased frequency of ventricular arrhythmias (including NSVT) in patients with HOCM. Thus, the severity of OSA was independently associated with more severe myocardial fibro…
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Prenatal diagnosis and management of junctional ectopic tachycardia Open
Junctional ectopic tachycardia (JET) is one of the rarest forms of fetal tachycardia. When associated with maternal anti-SSA (Sjogren) antibodies,1,2 JET is intermittent, with variable fetal heart rate (FHR) and decreases in frequency as g…
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Biomarkers of cardiovascular injury and stress are associated with increased frequency of ventricular ectopy: a population-based study Open
Increased level of NT-proBNP was independently associated with ventricular ectopy, whereas no independent association was observed between hs-TnI and hs-CRP levels and ventricular ectopy in this community-based sample.
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Premature Ventricular Complex is More Prevalent During Acute Exacerbated than Stable States of Chronic Obstructive Pulmonary Disease, and Is Related to Cardiac Troponin T Open
During acute exacerbation of chronic obstructive pulmonary disease (AECOPD), myocardial stress may be aggravated. Sparse data exist concerning the prevalence and correlates of cardiac arrhythmias in the stable and exacerbated states of COP…
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ECG changes in hospitalised patients with COVID-19 infection Open
The coronavirus disease 2019 (COVID-19) commonly involves the respiratory system but increasingly cardiovascular involvement is recognised. We assessed electrocardiogram (ECG) abnormalities in patients with COVID-19. We performed retrospec…
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Is the stroke volume during post-ectopic beat associated with ventricular premature complex-related symptoms? Open
Ventricular premature complex-related symptoms may not be associated with the amount of post-VPC SV.
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Hyperkalemia Presenting as Sinus Bradycardia, Junctional Rhythm and Atrial Bigeminy Open
The spectrum of electrocardiographic changes seen with hyperkalemia is known to progress gradually with increasing serum levels of potassium. Initial changes are limited to peaked T waves and QT shortening, which subsequently progress to p…
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Incidence of cardiac arrhythmias in patients with COVID-19 infection according to 24-hour electrocardiogram monitoring Open
Cardiac arrhythmias in patients with COVID-19 infection may be due to many pathophysiological factors. Further study on the structure of arrhythmias in this category of patients will reveal clinically significant arrhythmias and select the…
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Bigeminal potentials in the pulmonary vein indicate arrhythmogenic trigger of atrial fibrillation Open
Background The pulmonary veins (PVs) have unique electrophysiological properties triggering and maintaining atrial fibrillation (AF). Bigeminal PV electrical activity (PV bigeminy) during sinus rhythm has been reported; however, its mechan…
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Progesterone pretreatment reduces the incidence of drug‐induced torsades de pointes in atrioventricular node‐ablated isolated perfused rabbit hearts Open
Introduction Higher progesterone concentrations are protective against drug‐induced prolongation of ventricular repolarization. We tested the hypothesis that pretreatment with progesterone reduces the incidence of drug‐induced torsades de …
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Simultaneous assessment of mechanical and electrical function in Langendorff-perfused ex-vivo mouse hearts Open
Background The Langendorff-perfused ex-vivo isolated heart model has been extensively used to study cardiac function for many years. However, electrical and mechanical function are often studied separately—despite growing proof of a comple…
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Peri‐operative ventricular bigeminy and cardiomyopathy in elective surgery Open
Summary Premature ventricular contractions are common in the general population and are often seen during general anaesthesia. A high frequency of premature ventricular contractions may be associated with underlying left ventricular dysfun…
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Hypocalcemic Cardiomyopathy Due to Vitamin D Deficiency in a Very Old Man Open
To the Editor: Heart failure is a common health problem among older adults, arising out of multiple etiologic factors that are often irreversible,1 and reversible causes of myocardial dysfunction are often overlooked. A case of reversible …
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Evaluation of Morphology of Premature Ventricular Contraction on 12-Lead Electrocardiogram Open
Background-Evaluation of different morphology of premature ventricular contraction (PVC) in 12-lead ECG might reflect the presence or absence of myocardial diseases and determine PVC foci. It is important for ablation procedure and it can …
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Evaluation of premature ventricular complexes during in‐hospital ECG monitoring as a predictor of ventricular tachycardia in an intensive care unit cohort Open
In‐hospital electrocardiographic (ECG) monitors are typically configured to alarm for premature ventricular complexes (PVCs) due to the potential association of PVCs with ventricular tachycardia (VT). However, no contemporary hospital‐base…
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Implantation of a dual-chamber pacemaker in a patient with dextrocardia and sick sinus syndrome: a case report Open
Dextrocardia is a congenital abnormal position of the heart in which the main part of the heart is in the right chest, and the long axis of the heart points to the lower right. Cases of a combination of dextrocardia and sick sinus syndrome…
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Right ventricular lead induced ventricular arrhythmia—A rare complication of cardiac resynchronization therapy Open
Background A 53‐year‐old male with heart failure secondary to anterior wall myocardial infarction treated with cardiac resynchronization‐defibrillator (CRT‐D) device presented with ventricular arrhythmia: repetitive incessant slow ventricu…
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Confounding factors leading to misdiagnosing ventricular tachycardia as supraventricular in the emergency room Open
Studies conducted during the last 50 years have proposed electrocardiographic criteria and algorithms to determine if a wide QRS tachycardia is ventricular or supraventricular in origin. Sustained ventricular tachycardia is an uncommon rea…
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Multifocal ectopic premature Purkinje-related complexes syndrome in children Open
Key Teaching Points•Multifocal ectopic premature Purkinje-related complexes (MEPPC) are characterized by frequent polymorphic premature ventricular contractions (PVCs) of short coupling interval, sharp initial QRS deflection, relatively na…