Standardized uptake value
View article: [18F]Fluorodeoxyglucose Positron Emission Tomography for diagnosis and monitoring of acute <i>Staphylococcus aureus</i> vascular graft infection in a rat model
[18F]Fluorodeoxyglucose Positron Emission Tomography for diagnosis and monitoring of acute <i>Staphylococcus aureus</i> vascular graft infection in a rat model Open
Objectives Vascular graft or endograft infections (VGEI) pose a detrimental complication when using vascular grafts and are challenging to diagnose and treat. This study examined the progression of infection and the antimicrobial response …
View article: Potential value of [68Ga]Ga-FAPI-46 PET in patients with metastatic urothelial carcinoma: a bi-centric analysis
Potential value of [68Ga]Ga-FAPI-46 PET in patients with metastatic urothelial carcinoma: a bi-centric analysis Open
Purpose [ 68 Ga]Ga-FAPI-46 has shown promise for urothelial cancer (UC) detection. This study evaluates its diagnostic value versus contrast-enhanced CT (ceCT) and 2-[ 18 F]FDG PET in the largest bi-centric cohort to date. Methods Patients…
View article: Characteristics of pulmonary lymphoma on baseline 18F-FDG positron emission tomography/computed tomography and their clinical value in predicting treatment response
Characteristics of pulmonary lymphoma on baseline 18F-FDG positron emission tomography/computed tomography and their clinical value in predicting treatment response Open
View article: Development of 18F/11C-Labeled Pyrrolo-Pyridine/Pyrimidine LRRK2 Selective PET Radioligands
Development of 18F/11C-Labeled Pyrrolo-Pyridine/Pyrimidine LRRK2 Selective PET Radioligands Open
Background/Objectives: Leucine-rich repeat kinase 2 (LRRK2) is an enzyme implicated in Parkinson’s disease (PD) and a potential therapeutic target. LRRK2 PET radioligands could therefore function as imaging biomarkers for PD and as tools t…
View article: Figure 5 from Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models
Figure 5 from Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models Open
Polθ inhibitor ART899 combined with radiation causes significant tumor growth delay in vivo and is well tolerated. A, ART899 plasma concentration following oral dosage of ART899 at 50 or 150 mg/kg. Mouse plasma samples (n<…
View article: A Novel FAPI-Based Radiopharmaceutical for SPECT Imaging of Fibrotic Interstitial Lung Disease
A Novel FAPI-Based Radiopharmaceutical for SPECT Imaging of Fibrotic Interstitial Lung Disease Open
Objectives: Early and noninvasive detection of fibrotic interstitial lung disease (fILD) is a critical but unmet clinical necessity. This study aimed to evaluate the feasibility of using 99mTc-HYNIC-Glu(PEG4-oncoFAPi)2 (denoted as 99mTc-H-…
View article: Case Report: A case of necrotizing sarcoid granulomatosis mimicking metastatic tumor
Case Report: A case of necrotizing sarcoid granulomatosis mimicking metastatic tumor Open
This article presents a case study of a patient with early-stage lung cancer who received comprehensive management at our institution throughout the entire clinical course. During follow-up, multiple progressively enlarging solid nodules w…
View article: Shortened Acquisition Duration for Brain Tumor 11C-Methionine Positron Emission Tomography on Silicon Photomultiplier Positron Emission Tomography/Computed Tomography
Shortened Acquisition Duration for Brain Tumor 11C-Methionine Positron Emission Tomography on Silicon Photomultiplier Positron Emission Tomography/Computed Tomography Open
Positron emission tomography/computed tomography (PET/CT) scanners equipped with silicon photomultiplier detectors offer superior sensitivity and count-rate performance. The aim of this study was to evaluate the feasibility and impact of s…
View article: Quantitative Imaging Biomarkers as Prognostic Indicators in Squamous Cell Cervical Carcinoma: A Retrospective Cohort Analysis
Quantitative Imaging Biomarkers as Prognostic Indicators in Squamous Cell Cervical Carcinoma: A Retrospective Cohort Analysis Open
Objective To evaluate quantitative imaging biomarkers, including MRI tumor size, apparent diffusion coefficient (ADC), arterial-phase enhancement, and PET maximum standardized uptake value (SUVmax), as prognostic indicators of overall surv…
View article: Baseline PARP-1 PET imaging in patients with advanced solid tumors with DNA damage response mutations
Baseline PARP-1 PET imaging in patients with advanced solid tumors with DNA damage response mutations Open
Purpose Inhibitors of poly(ADP-ribose) polymerase (PARP), an enzyme with numerous roles in DNA damage response signaling, represent a class of anti-cancer drugs approved for treating solid tumors with defects in the DNA damage response. Ho…
View article: Distinguishing between carcinoid tumors and hamartomas: the diagnostıc value of FDG PET/CT
Distinguishing between carcinoid tumors and hamartomas: the diagnostıc value of FDG PET/CT Open
Objective Primary lung carcinoid tumors are well-differentiated malignant neuroendocrine neoplasms classified as typical carcinoids (low grade) and atypical carcinoids (intermediate grade), accounting for 0.5–5% of all lung cancers. Differ…
View article: [18F]FDG-PET/CT-based evaluation of tumor response kinetics during induction chemotherapy and concurrent radiochemotherapy in stage II - III small-cell lung cancer
[18F]FDG-PET/CT-based evaluation of tumor response kinetics during induction chemotherapy and concurrent radiochemotherapy in stage II - III small-cell lung cancer Open
Purpose Evaluation of interim-[ 18 F]FDG-PET/CT as a prognostic tool in limited disease small cell lung cancer (SCLC). Methods We included 35 patients with limited disease SCLC from a prospective institutional registry in this retrospectiv…
View article: Evaluation of the Prognostic Value of Quantitative and Visual Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (FDG PET/CT) Parameters in Superficial Esophageal Squamous Cell Carcinoma
Evaluation of the Prognostic Value of Quantitative and Visual Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (FDG PET/CT) Parameters in Superficial Esophageal Squamous Cell Carcinoma Open
View article: Organ-based tumor distribution for predicting prognosis in small-cell lung cancer using fluorodeoxyglucose positron emission tomography/computed tomography
Organ-based tumor distribution for predicting prognosis in small-cell lung cancer using fluorodeoxyglucose positron emission tomography/computed tomography Open
View article: External Validation of Nomograms for Predicting Pelvic Lymph Node Metastases in Patients with Prostate Cancer and the Added Value of the Prostate-specific Membrane Antigen Positron Emission Tomography–based PRIMARY Score
External Validation of Nomograms for Predicting Pelvic Lymph Node Metastases in Patients with Prostate Cancer and the Added Value of the Prostate-specific Membrane Antigen Positron Emission Tomography–based PRIMARY Score Open
View article: Multi-Institutional Verification of a Novel Predictor (Volume-Scaled SUVmax) for Successful Biology-Guided Radiotherapy Delivery of Small Targets
Multi-Institutional Verification of a Novel Predictor (Volume-Scaled SUVmax) for Successful Biology-Guided Radiotherapy Delivery of Small Targets Open
Background/Objectives: The aim of this study was to establish the relationship between target size and the required diagnostic PET maximum standard uptake value (SUVmax) thresholds needed for successful Biology-guided Radiotherapy (BgRT) d…
View article: 18Fluorine-sodium fluoride positron emission tomography to evaluate arterial calcification in patients with chronic kidney disease: a pilot study
18Fluorine-sodium fluoride positron emission tomography to evaluate arterial calcification in patients with chronic kidney disease: a pilot study Open
18 Fluorine-Sodium Fluoride Positron Emission Tomography ( 18 F-NaF PET) allows for the detection of arterial micro-calcification, but its data on people with chronic kidney disease (CKD) is limited. This pilot study aimed to determine the…
View article: Combined [¹¹C]PBR28 PET and Quantitative T1 Mapping Reveal Choroid Plexus Alterations in Multiple Sclerosis
Combined [¹¹C]PBR28 PET and Quantitative T1 Mapping Reveal Choroid Plexus Alterations in Multiple Sclerosis Open
Background The choroid plexus (CP), central to cerebrospinal fluid (CSF) regulation and immune cell trafficking, has been implicated in multiple sclerosis (MS). Objectives We investigated TSPO-PET standardized uptake value ratio (SUVR) in …
View article: Comparative Evaluation of [68Ga]Ga-Fibroblast Activation Protein Inhibitor vs. [18F]FDG as a Novel Radiotracer for Biology-Guided Image Radiotherapy
Comparative Evaluation of [68Ga]Ga-Fibroblast Activation Protein Inhibitor vs. [18F]FDG as a Novel Radiotracer for Biology-Guided Image Radiotherapy Open
Background/Objectives: Biology-guided radiotherapy (BgRT) is a novel technology utilizing PET radiotracer emissions to deliver image-guided adaptive RT. 18F-Fluorodeoxyglucose ([18F]FDG) is the most common PET radiotracer but has backgroun…
View article: DIAGNOSTIC CAPABILITIESOF 68GA-FAPI PET/CT IN GASTRIC CANCER
DIAGNOSTIC CAPABILITIESOF 68GA-FAPI PET/CT IN GASTRIC CANCER Open
Relevance: Gastric cancer remains a significant medical issue due to its high incidence and mortality rates. Hybrid imaging techniques, including positron emission tomography/computed tomography (PET/CT), play an important role in the diag…
View article: Early pleuroparenchymal fibroelastosis mimicking lung malignancy: A case report
Early pleuroparenchymal fibroelastosis mimicking lung malignancy: A case report Open
BACKGROUND Pleuroparenchymal fibroelastosis (PPFE) is a rare form of interstitial lung disease affecting the upper lobes. Its atypical radiological appearance frequently mimics lung malignancy, complicating early diagnosis. This case highl…
View article: Diagnostic Performance of [18F]FDG PET/MRI and [18F]FDG PET/CT in the Detection of Lymph Node Metastases in Colorectal Cancer: A Meta-analysis
Diagnostic Performance of [18F]FDG PET/MRI and [18F]FDG PET/CT in the Detection of Lymph Node Metastases in Colorectal Cancer: A Meta-analysis Open
Colorectal cancer (CRC) ranks among the leading causes of cancer-related mortality worldwide. Accurate detection of lymph node metastases plays a crucial role in determining disease stage and guiding treatment decisions. Fluorine-18 fluoro…
View article: Positron emission tomography/computed tomography in risk-factor-negative young female with malignant pleural mesothelioma: A case report and review of literature
Positron emission tomography/computed tomography in risk-factor-negative young female with malignant pleural mesothelioma: A case report and review of literature Open
BACKGROUND Malignant pleural mesothelioma (MPM), a rare aggressive malignancy, is primarily caused by asbestos exposure. MPM typically affects older adults (median age, 76 years), is uncommon in those under age 50 years and shows male pred…
View article: Diagnostic accuracy of a machine learning approach applied to delayed [ 18F]-Florbetaben positron emission tomography in patients with suspected light-chain cardiac amyloidosis
Diagnostic accuracy of a machine learning approach applied to delayed [ 18F]-Florbetaben positron emission tomography in patients with suspected light-chain cardiac amyloidosis Open
Purpose The diagnosis of AL-CA is often difficult and requires invasive assessment by tissue biopsy. The purpose of the study was to evaluate the diagnostic accuracy of a machine learning approach applied to delayed [ 18 F]-flor…
View article: Assessing Ga-68 PSMA PET/CT Parameters in Relation to Clinical and Pathological Risk Stratification in Localized Prostate Cancer
Assessing Ga-68 PSMA PET/CT Parameters in Relation to Clinical and Pathological Risk Stratification in Localized Prostate Cancer Open
Background Accurate pre-operative risk stratification in prostate cancer is essential, yet conventional imaging poorly reflects tumour burden or aggressiveness. Gallium-68 Prostate-Specific Membrane Antigen Positron Emission Tomography/Com…
View article: 18F-FAPI-04 PET/CT in the evaluation of ground-glass nodules less than 3 cm in diameter comparing to 18F-FDG PET/CT
18F-FAPI-04 PET/CT in the evaluation of ground-glass nodules less than 3 cm in diameter comparing to 18F-FDG PET/CT Open
Background This study aimed to evaluate the clinical usefulness of fluorine 18 F−FAPI-04 PET/CT in diagnosing ground-glass nodules that are less than 3 cm in diameter in comparison with fluorine 18 F-FDG PET/CT. Methods Prospective analysi…
View article: О'ZBEKISTОNNING SUV VA SUV MANBALARI BОRASIDA QО'SHNI DAVLATLARI BILAN О'ZARО HAMKОRLIGI
О'ZBEKISTОNNING SUV VA SUV MANBALARI BОRASIDA QО'SHNI DAVLATLARI BILAN О'ZARО HAMKОRLIGI Open
Mazkur tezisda O‘zbekiston Respublikasining Markaziy Osiyo mintaqasidagi suv resurslaridan oqilona foydalanish va ularni boshqarish sohasidagi tashqi siyosati hamda qo‘shni davlatlar bilan olib borayotgan hamkorlik faoliyati yoritilg…
View article: О'ZBEKISTОNNING SUV VA SUV MANBALARI BОRASIDA QО'SHNI DAVLATLARI BILAN О'ZARО HAMKОRLIGI
О'ZBEKISTОNNING SUV VA SUV MANBALARI BОRASIDA QО'SHNI DAVLATLARI BILAN О'ZARО HAMKОRLIGI Open
Mazkur tezisda O‘zbekiston Respublikasining Markaziy Osiyo mintaqasidagi suv resurslaridan oqilona foydalanish va ularni boshqarish sohasidagi tashqi siyosati hamda qo‘shni davlatlar bilan olib borayotgan hamkorlik faoliyati yoritilgan. Su…
View article: Geometric Modeling of Hippocampal Tau Deposition: A Surface-Based Framework for Covariate Analysis and Off-Target Contamination Detection
Geometric Modeling of Hippocampal Tau Deposition: A Surface-Based Framework for Covariate Analysis and Off-Target Contamination Detection Open
We introduce a framework combining geometric modeling with disease progression analysis to investigate tau deposition in Alzheimer's disease (AD) using positron emission tomography (PET) data. Focusing on the hippocampus, we construct a pr…
View article: Geometric Modeling of Hippocampal Tau Deposition: A Surface-Based Framework for Covariate Analysis and Off-Target Contamination Detection
Geometric Modeling of Hippocampal Tau Deposition: A Surface-Based Framework for Covariate Analysis and Off-Target Contamination Detection Open
We introduce a framework combining geometric modeling with disease progression analysis to investigate tau deposition in Alzheimer's disease (AD) using positron emission tomography (PET) data. Focusing on the hippocampus, we construct a pr…