Gastrocnemius muscle
View article: COMPARISON OF EFFECTIVENESS OF PASSIVE STRETCHINGS VERSUS NERVE MOBILIZATIONS ON PLANTAR FLEXOR SPASTICITY, ANKLE ROM, AND GAIT VELOCITY IN SUBACUTE STROKE SUBJECTS
COMPARISON OF EFFECTIVENESS OF PASSIVE STRETCHINGS VERSUS NERVE MOBILIZATIONS ON PLANTAR FLEXOR SPASTICITY, ANKLE ROM, AND GAIT VELOCITY IN SUBACUTE STROKE SUBJECTS Open
Introduction: Stroke is a major cause of long-term disability worldwide, and often results in motor impairments such as spasticity, especially in the plantar flexor muscles of the lower limb. This spasticity can limit ankle movement, affec…
View article: Disulfiram inhibits Gasdermin D pores formation and improves insulin-dependent glucose uptake and glucose homeostasis in skeletal muscle of obesity-induced insulin-resistant mice
Disulfiram inhibits Gasdermin D pores formation and improves insulin-dependent glucose uptake and glucose homeostasis in skeletal muscle of obesity-induced insulin-resistant mice Open
Insulin resistance (IR), which involves impaired insulin signaling diminished insulin sensitivity in skeletal muscle, is closely associated with chronic low-grade inflammation. A key mediator of this process is the NLRP3 inflammasome, whic…
View article: The effect of a combined exercise program on different surfaces on gastrocnemius muscle activation in young athletes
The effect of a combined exercise program on different surfaces on gastrocnemius muscle activation in young athletes Open
View article: COMPARISON OF EFFECTIVENESS OF PASSIVE STRETCHINGS VERSUS NERVE MOBILIZATIONS ON PLANTAR FLEXOR SPASTICITY, ANKLE ROM, AND GAIT VELOCITY IN SUBACUTE STROKE SUBJECTS
COMPARISON OF EFFECTIVENESS OF PASSIVE STRETCHINGS VERSUS NERVE MOBILIZATIONS ON PLANTAR FLEXOR SPASTICITY, ANKLE ROM, AND GAIT VELOCITY IN SUBACUTE STROKE SUBJECTS Open
Introduction: Stroke is a major cause of long-term disability worldwide, and often results in motor impairments such as spasticity, especially in the plantar flexor muscles of the lower limb. This spasticity can limit ankle movement, affec…
View article: The Effect of Using Infrared and Massage Gun Based on Pain Period on Reducing Gastrocnemius Muscle Pain
The Effect of Using Infrared and Massage Gun Based on Pain Period on Reducing Gastrocnemius Muscle Pain Open
Pain is an unpleasant sensory and emotional experience caused by tissue damage, either actual or potential. One of the causes of pain is the presence of DOMS (Delayed Onset Muscle Soreness) in muscles that contract for a long time or exces…
View article: Stimulation at the frontal cortex influences the exercise activity and skeletal muscle status in senescence-accelerating mice
Stimulation at the frontal cortex influences the exercise activity and skeletal muscle status in senescence-accelerating mice Open
Senescence-associated frailty and sarcopenia are global challenges. We here investigated neuronal activity and skeletal muscle biology in senescence-accelerated mouse prone 8 (SAMP8) mice with scalp acupuncture stimulation (SAPS). Excise a…
View article: Ultrasound elastography to guide compression therapy for gastrocnemius trigger points in runners
Ultrasound elastography to guide compression therapy for gastrocnemius trigger points in runners Open
Myofascial pain syndrome (MPS) is one of the most common musculoskeletal pain disorders affecting athletes. This is an important clinical issue because MPS has a negative impact on athlete achievement as with sporting injuries. We screened…
View article: Role of Calpains in Uremia-Related Functional and Structural Muscle Changes: Protective Effect of Calpastatin Overexpression
Role of Calpains in Uremia-Related Functional and Structural Muscle Changes: Protective Effect of Calpastatin Overexpression Open
Sarcopenia, the progressive loss of muscle mass and strength, is a common complication in patients with chronic kidney disease (CKD). This condition arises from a combination of factors including reduced physical activity, insufficient pro…
View article: Physiological swelling imaging in human calf under stocking compression by sparse Bayesian learning implemented into electrical impedance tomography (SBL-EIT)
Physiological swelling imaging in human calf under stocking compression by sparse Bayesian learning implemented into electrical impedance tomography (SBL-EIT) Open
Physiological swelling in human calf has been imaged under stocking compression by the sparse Bayesian learning implemented into electrical impedance tomography (SBL-EIT) to evaluate the in situ treatment effect of various compression pres…
View article: MRI assessment of leg muscle size and composition after a 7-day head-down bed rest
MRI assessment of leg muscle size and composition after a 7-day head-down bed rest Open
Objective: To investigate the effects of 7-day −6° head-down bed rest (HDBR) on lower limb muscle volume, fat, and muscle strength in healthy males. Materials and Methods: In this prospective study, thigh and calf proton density fat fracti…
View article: Effects of repetition duration on skeletal muscle hypertrophy in a rat model of resistance exercise
Effects of repetition duration on skeletal muscle hypertrophy in a rat model of resistance exercise Open
This study aimed to elucidate the effects of repetition duration (contraction duration for each repetition) of resistance exercise on muscle hypertrophy and its underlying mechanisms using a rat exercise model. Male Sprague-Dawley rats wer…
View article: The Monocrotaline Model of Hypertension Leads to Cachexia in Male but Not Female Mice
The Monocrotaline Model of Hypertension Leads to Cachexia in Male but Not Female Mice Open
Background The monocrotaline (MCT) model of cardiac cachexia is a pharmaceutical approach to pulmonary hypertension that has been used to study heart failure and muscle wasting in rodents; however, little is known of how this pyrrolizidine…
View article: Calf Knows Best: Gastrocnemius Sonoelastography as a Sensitive Marker of Muscle Mass in End-Stage Kidney Disease
Calf Knows Best: Gastrocnemius Sonoelastography as a Sensitive Marker of Muscle Mass in End-Stage Kidney Disease Open
Background : Muscle loss and weakness are hallmarks of end-stage kidney disease (ESKD), driving disability and poor outcomes. Traditional assessments of muscle health are often invasive, time-consuming, or insensitive. Sonoelastography, wh…
View article: Gastrocnemius Echo Intensity Is Associated with Walking Distance and Hemodynamic Improvements After Endovascular Therapy in Lower Extremity Artery Disease
Gastrocnemius Echo Intensity Is Associated with Walking Distance and Hemodynamic Improvements After Endovascular Therapy in Lower Extremity Artery Disease Open
Background: This study aimed to validate the associations between the echo intensity (EI) of the gastrocnemius muscle before endovascular therapy (EVT) and post-EVT changes in the 6-min walk distance (6MWD), ankle–brachial index (ABI), and…
View article: Vincristine impairs musculoskeletal development in pediatric mice
Vincristine impairs musculoskeletal development in pediatric mice Open
View article: Effect of Allogenic Mesenchymal Stem Cell Injection on Functional Repair Outcomes Following Skeletal Muscle Laceration Injury
Effect of Allogenic Mesenchymal Stem Cell Injection on Functional Repair Outcomes Following Skeletal Muscle Laceration Injury Open
Background: Skeletal muscle laceration injuries remain a clinical challenge owing to limited and often delayed functional recovery. Surgical repair often fails to fully restore injured muscle, causing fibrosis and functional impairments. M…
View article: Functional Assessment of Peroneal Muscles Using Ultrasound Imaging in Chronic Ankle Instability
Functional Assessment of Peroneal Muscles Using Ultrasound Imaging in Chronic Ankle Instability Open
Background Lateral ankle sprains (LAS) result in chronic ankle instability (CAI), causing ongoing instability. Although peroneal muscle weakness is documented in CAI, surface electromyography shows similar activation patterns between CAI a…
View article: Influence of Neonatal Exposure to Hyperoxia on Skeletal Muscle in a Rat Model
Influence of Neonatal Exposure to Hyperoxia on Skeletal Muscle in a Rat Model Open
Background/Objectives: Premature births below 32 weeks of gestation generally require respiratory oxygen support, leading to a relatively hyperoxic environment compared to in utero conditions. Transient hyperoxia exposure has been linked t…
View article: Simulated gastrocnemius traction alters interfragmentary motion in Hoffa fracture fixation
Simulated gastrocnemius traction alters interfragmentary motion in Hoffa fracture fixation Open
View article: Platelet bioenergetics correlate with skeletal muscle respiration in a murine model of type II diabetes
Platelet bioenergetics correlate with skeletal muscle respiration in a murine model of type II diabetes Open
Mitochondrial bioenergetic research in skeletal muscle is limited by the need for biopsies. We executed a proof-of-concept study to evaluate whether blood platelets could serve as a minimally invasive surrogate for skeletal muscle mitochon…
View article: The gastrocnemius and soleus muscles deficits in functional ankle instability: an observational study
The gastrocnemius and soleus muscles deficits in functional ankle instability: an observational study Open
View article: Changes in motor unit conduction velocity after unilateral lower‐limb suspension and active recovery are correlated with muscle ion channel gene expression
Changes in motor unit conduction velocity after unilateral lower‐limb suspension and active recovery are correlated with muscle ion channel gene expression Open
The effects of muscle disuse on the propagation of action potentials along motor unit (MU) muscle fibres, a key process for effective muscle activation and force generation, remain poorly understood. The aim of this study was to investigat…
View article: Donepezil treatment, alone or combined with exercise, enhances skeletal muscle function in healthy and advanced aging disease mouse models.
Donepezil treatment, alone or combined with exercise, enhances skeletal muscle function in healthy and advanced aging disease mouse models. Open
Reduced muscle mass and function are hallmarks of aging, increased frailty, and reduced resilience. There are no clinically-approved interventions besides exercise to improve muscle quality and function in the elderly. We recently found th…
View article: Matcha Green Tea Promotes Training-induced Anabolic Response of Skeletal Muscle in Mice
Matcha Green Tea Promotes Training-induced Anabolic Response of Skeletal Muscle in Mice Open
Matcha green tea contains various bioactive compounds, such as catechins and dietary fibers. Daily consumption of matcha green tea enhances exercise-induced adaptations to skeletal muscle hypertrophy and strength in humans. However, interv…
View article: Novel insights into the effects of JMV2894, a growth hormone secretagogue, in Duchenne muscular dystrophy: A preclinical study in the D2-mdx mouse model
Novel insights into the effects of JMV2894, a growth hormone secretagogue, in Duchenne muscular dystrophy: A preclinical study in the D2-mdx mouse model Open
Growth hormone secretagogues (GHSs) are gaining interest as promising therapeutics for Duchenne muscular dystrophy (DMD) due to their broad activity profile and proven benefits in other muscle-wasting conditions. We previously found that J…
View article: Heavy alcohol use exacerbates skeletal myopathy in peripheral artery disease
Heavy alcohol use exacerbates skeletal myopathy in peripheral artery disease Open
Peripheral artery disease (PAD) is an age-associated vascular condition that contributes to progressive skeletal muscle dysfunction, marked by oxidative stress, mitochondrial abnormalities, and muscle atrophy. Chronic alcohol misuse indepe…
View article: Pediatric CHOP Chemotherapy Acutely Disrupts Satellite‑Cell Dynamics and Blunts Muscle Mass in a Sex‑Specific Manner
Pediatric CHOP Chemotherapy Acutely Disrupts Satellite‑Cell Dynamics and Blunts Muscle Mass in a Sex‑Specific Manner Open
Pediatric cancer survival now exceeds 85 percent owing, in part, advances and use of combination chemotherapy treatments such as CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone). Despite its efficacy, CHOP may cause off-ta…
View article: Evaluation of the Relationships of Fisetin and Atorvastatin with Adipokine, Hepatokine, Myokine Profiles and Metabolic Parameters in Rats Fed with High-Fat Diet
Evaluation of the Relationships of Fisetin and Atorvastatin with Adipokine, Hepatokine, Myokine Profiles and Metabolic Parameters in Rats Fed with High-Fat Diet Open
Objective The aim of this study is to evaluate the effects of fisetin and atorvastatin administration on metabolic parameters and adipokine, hepatokine, and myokine profiles in rats fed a high-fat diet (HFD). Additionally, the effects of t…
View article: Perfluorooctane sulfonic acid (PFOS) perturbs skeletal muscle oxidative phosphorylation by a different mechanism than liver
Perfluorooctane sulfonic acid (PFOS) perturbs skeletal muscle oxidative phosphorylation by a different mechanism than liver Open
We evaluated PFOS metabolic toxicity in skeletal muscle where not much is known and then compared it to liver metabolic toxicity as measured by bioaccumulation, sarcopenia (muscle loss), RIFS (Respirometry in Frozen Samples; OXPHOS in mito…
View article: STX4 Is Indispensable for Mitochondrial Homeostasis in Skeletal Muscle
STX4 Is Indispensable for Mitochondrial Homeostasis in Skeletal Muscle Open
Background Mitochondrial homeostasis is vital for optimal skeletal muscle integrity. Mitochondrial quality control (MQC) mechanisms that are essential for maintaining proper functions of mitochondria include mitochondrial biogenesis, dynam…