Domperidone
View article: A Review on Development and Validation for the Simultaneous Estimation of Lansoprazole and Domperidone in Bulk and Capsule Dosage Form
A Review on Development and Validation for the Simultaneous Estimation of Lansoprazole and Domperidone in Bulk and Capsule Dosage Form Open
Lansoprazole is an effective proton pump inhibitor utilized for managing various acid-related disorders, such as ulcers and gastroesophageal reflux disease (GERD), by significantly reducing stomach acid production. It has demonstrated a ge…
View article: DEVELOPMENT AND CHARACTERIZATION OF DOMPERIDONE MALEATE ORAL DISSOLVING FILMS: INFLUENCE OF POLYMER CONCENTRATION ON IN-VITRO DRUG RELEASE
DEVELOPMENT AND CHARACTERIZATION OF DOMPERIDONE MALEATE ORAL DISSOLVING FILMS: INFLUENCE OF POLYMER CONCENTRATION ON IN-VITRO DRUG RELEASE Open
Background: The oral mucosa serves as an effective and selective site for systemic drug delivery due to its high permeability and large surface area, facilitating rapid absorption. Additionally, this route avoids the pain associated with i…
View article: DEVELOPMENT AND CHARACTERIZATION OF DOMPERIDONE MALEATE ORAL DISSOLVING FILMS: INFLUENCE OF POLYMER CONCENTRATION ON IN-VITRO DRUG RELEASE
DEVELOPMENT AND CHARACTERIZATION OF DOMPERIDONE MALEATE ORAL DISSOLVING FILMS: INFLUENCE OF POLYMER CONCENTRATION ON IN-VITRO DRUG RELEASE Open
Background: The oral mucosa serves as an effective and selective site for systemic drug delivery due to its high permeability and large surface area, facilitating rapid absorption. Additionally, this route avoids the pain associated with i…
View article: DEVELOPMENT AND CHARACTERIZATION OF TRANSDERMAL PATCH OF ONDANSETRON MICROSPONGE TO TREAT CHEMOTHERAPY INDUCED NAUSEA AND VOMITING
DEVELOPMENT AND CHARACTERIZATION OF TRANSDERMAL PATCH OF ONDANSETRON MICROSPONGE TO TREAT CHEMOTHERAPY INDUCED NAUSEA AND VOMITING Open
The present study aims to develop ondansetron microsponge loaded transdermal patch for the management of Chemotherapy-induced nausea vomiting (CINV). Method and results: Microsponges were prepared by using the quasi-emulsion solvent diffus…
View article: DEVELOPMENT AND CHARACTERIZATION OF TRANSDERMAL PATCH OF ONDANSETRON MICROSPONGE TO TREAT CHEMOTHERAPY INDUCED NAUSEA AND VOMITING
DEVELOPMENT AND CHARACTERIZATION OF TRANSDERMAL PATCH OF ONDANSETRON MICROSPONGE TO TREAT CHEMOTHERAPY INDUCED NAUSEA AND VOMITING Open
The present study aims to develop ondansetron microsponge loaded transdermal patch for the management of Chemotherapy-induced nausea vomiting (CINV). Method and results: Microsponges were prepared by using the quasi-emulsion solvent diffus…
View article: A Quality Control Study of Generic & Branded Domperidone Hydrochloride Tablet
A Quality Control Study of Generic & Branded Domperidone Hydrochloride Tablet Open
The present study compares generic Domperidone Hydrochloride tablets against their branded counterparts. Physical and chemical parameters were carried out, such as external characteristics, weight variability, hardness, and friability. Che…
View article: A Quality Control Study of Generic & Branded Domperidone Hydrochloride Tablet
A Quality Control Study of Generic & Branded Domperidone Hydrochloride Tablet Open
The present study compares generic Domperidone Hydrochloride tablets against their branded counterparts. Physical and chemical parameters were carried out, such as external characteristics, weight variability, hardness, and friability. Che…
View article: Prevalence of gastroduodenal disorders in patients with thyroid dysfunction
Prevalence of gastroduodenal disorders in patients with thyroid dysfunction Open
Background. The functional state of the digestive system depends on complex neurohumoral regulatory mechanisms. Given the ability of thyroid hormones to influence gastrointestinal homeostasis, it is essential to assess the functional state…
View article: mGnRHa and Domperidone in separated PLGA microspheres enhance spermiation in Goldfish (Carassius auratus)
mGnRHa and Domperidone in separated PLGA microspheres enhance spermiation in Goldfish (Carassius auratus) Open
Artificial reproduction in fish species with strong dopaminergic inhibition typically relies on acute hormone injections, while controlled-release strategies remain underutilized. This study aimed to develop, for the first time, separately…
View article: Chitosan-based nanoconjugated hormone delivery boosts reproductive efficiency in male Labeo rohita
Chitosan-based nanoconjugated hormone delivery boosts reproductive efficiency in male Labeo rohita Open
Hormone-induced breeding is pivotal in freshwater aquaculture, yet conventional gonadotropin-releasing hormone analogues (GnRH-a) are limited by their rapid degradation and cause stress associated with high-dose injections. Chitosan nanoca…
View article: What are the most effective treatments for nausea and vomiting in pregnancy?
What are the most effective treatments for nausea and vomiting in pregnancy? Open
The literature outlines a combination of pharmacological and non-pharmacological strategies for effectively managing nausea and vomiting in pregnancy, with doxylamine-pyridoxine as a first-line treatment and others like ondansetron and met…
View article: What are the most effective treatments for nausea and vomiting in pregnancy?
What are the most effective treatments for nausea and vomiting in pregnancy? Open
The literature outlines a combination of pharmacological and non-pharmacological strategies for effectively managing nausea and vomiting in pregnancy, with doxylamine-pyridoxine as a first-line treatment and others like ondansetron and met…
View article: What is the efficacy of domperidone in treating orthostatic hypotension?
What is the efficacy of domperidone in treating orthostatic hypotension? Open
The literature indicates domperidone may have some benefit in treating orthostatic hypotension associated with dopaminergic therapies in Parkinson's Disease, though evidence is not conclusive.
View article: What is the efficacy of domperidone in treating orthostatic hypotension?
What is the efficacy of domperidone in treating orthostatic hypotension? Open
The literature indicates domperidone may have some benefit in treating orthostatic hypotension associated with dopaminergic therapies in Parkinson's Disease, though evidence is not conclusive.
View article: Is domperidone effective in increasing milk supply in breastfeeding mothers?
Is domperidone effective in increasing milk supply in breastfeeding mothers? Open
Domperidone is described in the literature as potentially effective for increasing milk supply in mothers of preterm infants but requires careful consideration of risks and benefits, particularly due to safety concerns.
View article: Is domperidone effective in increasing milk supply in breastfeeding mothers?
Is domperidone effective in increasing milk supply in breastfeeding mothers? Open
Domperidone is described in the literature as potentially effective for increasing milk supply in mothers of preterm infants but requires careful consideration of risks and benefits, particularly due to safety concerns.
View article: What is the best antiemetic for someone who has experienced akathisia with metoclopramide?
What is the best antiemetic for someone who has experienced akathisia with metoclopramide? Open
When akathisia occurs with metoclopramide, alternative options such as domperidone and combinations of other antiemetics with diphenhydramine may be used to reduce side effects.
View article: Is domperidone suitable to take with lithium?
Is domperidone suitable to take with lithium? Open
No direct interaction is reported between domperidone and lithium, but monitoring for side effects and maintaining lithium levels within the therapeutic range is important.
View article: Is domperidone suitable to take with lithium?
Is domperidone suitable to take with lithium? Open
No direct interaction is reported between domperidone and lithium, but monitoring for side effects and maintaining lithium levels within the therapeutic range is important.
View article: What is the best antiemetic for someone who has experienced akathisia with metoclopramide?
What is the best antiemetic for someone who has experienced akathisia with metoclopramide? Open
When akathisia occurs with metoclopramide, alternative options such as domperidone and combinations of other antiemetics with diphenhydramine may be used to reduce side effects.
View article: What is the use of pyridoxine (Vitamin B6) in reducing prolactin levels?
What is the use of pyridoxine (Vitamin B6) in reducing prolactin levels? Open
Pyridoxine can reduce prolactin levels, especially at high doses, but is generally less effective than dopaminergic agonists, particularly for lactation suppression.
View article: What is the use of pyridoxine (Vitamin B6) in reducing prolactin levels?
What is the use of pyridoxine (Vitamin B6) in reducing prolactin levels? Open
Pyridoxine can reduce prolactin levels, especially at high doses, but is generally less effective than dopaminergic agonists, particularly for lactation suppression.
View article: Repurposing terfenadine and domperidone for inhibition of apoptotic gene association in colorectal cancer: A system pharmacology approach integrated with molecular docking, MD simulations, and post-MD simulation analysis
Repurposing terfenadine and domperidone for inhibition of apoptotic gene association in colorectal cancer: A system pharmacology approach integrated with molecular docking, MD simulations, and post-MD simulation analysis Open
Colorectal cancer (CRC) remains a leading cause of global cancer mortality, underscoring the need for novel therapeutic strategies. This study used a systems pharmacology approach integrated with molecular docking and molecular dynamics (M…
View article: FORMULATION AND OPTIMIZATION OF DOMPERIDONE-LOADED LIQUID SNEDDS: CHARACTERIZATION AND IN-VITRO EVALUATION
FORMULATION AND OPTIMIZATION OF DOMPERIDONE-LOADED LIQUID SNEDDS: CHARACTERIZATION AND IN-VITRO EVALUATION Open
This research concentrated on developing and optimizing domperidone-loaded Self- nanoemulsifying drug delivery system (SNEDDS) to enhance solubility, stability, and availability. Domperidone (DOM), a lipophilic drug characterized by its li…
View article: Oral Administration of GnRH and Domperidone via Gel Feed and Their Effect on Reproductive Performance of Devario devario (Bengal Danio), an Ornamental Fish
Oral Administration of GnRH and Domperidone via Gel Feed and Their Effect on Reproductive Performance of Devario devario (Bengal Danio), an Ornamental Fish Open
This study investigated the effects of dietary Gonadotropin-releasing hormone (GnRH) and domperidone on the reproductive performance of Devario devario during a 40-day trial. Five treatment groups received varying doses of GnRH (100, 50, 2…
View article: D-pinitol modulates the anti-emetic effects of aprepitant, domperidone, and ondansetron in chicks
D-pinitol modulates the anti-emetic effects of aprepitant, domperidone, and ondansetron in chicks Open
View article: Prescribing trends of fixed-dose combination of domperidone and proton-pump inhibitor across tertiary care centers in India, is the combination rational?
Prescribing trends of fixed-dose combination of domperidone and proton-pump inhibitor across tertiary care centers in India, is the combination rational? Open
BACKGROUND: There have been concerns over the rationality of prescribing practices of fixed-dose combinations (FDCs) available in India. The FDC of domperidone and pantoprazole recently emerged as a top-selling product at Janaushadhi Kendr…
View article: A rare case of antidepressant discontinuation syndrome triggered by domperidone: Clinical insights and literature review
A rare case of antidepressant discontinuation syndrome triggered by domperidone: Clinical insights and literature review Open
Antidepressant discontinuation syndrome is commonly observed among patients who abruptly discontinue or reduce the dosage of an antidepressant that has been administered for at least 6 weeks. Common manifestations may include flu-like symp…
View article: Development and Validation of Stability Indicating Method for Simultaneous Estimation of Famotidine and Domperidone in Bulk and Tablet Dosage Forms Using RP-HPLC
Development and Validation of Stability Indicating Method for Simultaneous Estimation of Famotidine and Domperidone in Bulk and Tablet Dosage Forms Using RP-HPLC Open
A novel, precise, and accurate Reverse Phase-High Performance Liquid Chromatography (RP- HPLC) method was developed and validated for the simultaneous estimation of Famotidine (FAM) and Domperidone (DOM) in bulk and tablet dosage forms. Th…
View article: An Extremely Rare Case of Gastroptosis Treated Successfully with Itopride in a Patient with Parkinson’s Disease
An Extremely Rare Case of Gastroptosis Treated Successfully with Itopride in a Patient with Parkinson’s Disease Open
A rare condition known as gastroptosis causes the major curvature of the stomach to shift downward and towards the pelvis. While some are asymptomatic, others experience symptoms. Cross-sectional imaging, or barium X-rays, are diagnostic. …