Choroid
View article: Hemisphere Model - Step 2
Hemisphere Model - Step 2 Open
With all arachnoid and vascular structures removed, the depth and height of sulci and gyri, corpus callosum and all segments, fornix, lateral and third ventricle and choroid plexus, anterior commissure, thalamus, olfactory and optic nerves…
View article: Hemisphere Model - Step 2
Hemisphere Model - Step 2 Open
With all arachnoid and vascular structures removed, the depth and height of sulci and gyri, corpus callosum and all segments, fornix, lateral and third ventricle and choroid plexus, anterior commissure, thalamus, olfactory and optic nerves…
View article: Linking Megalin, Cubilin, Caveolin-1, GIPC1 and Dab2IP Expression to Ocular Tumorigenesis: Profiles in Retinoblastoma, Choroidal Melanoma, and the Normal Human Eye
Linking Megalin, Cubilin, Caveolin-1, GIPC1 and Dab2IP Expression to Ocular Tumorigenesis: Profiles in Retinoblastoma, Choroidal Melanoma, and the Normal Human Eye Open
Background/Objectives: Retinoblastoma (RB) and uveal melanoma (UM) remain vision-threatening and lethal ocular malignancies with limited molecular markers of differentiation state and prognosis. We investigated whether proteins governing e…
View article: CASE REPORT: RARE CASE OF RETROORBITAL CHOROID MENINGIOMA TREATED WITH PROTON THERAPY
CASE REPORT: RARE CASE OF RETROORBITAL CHOROID MENINGIOMA TREATED WITH PROTON THERAPY Open
View article: Severe bilateral chorioretinopathy associated with ipilimumab in a patient with metastatic melanoma
Severe bilateral chorioretinopathy associated with ipilimumab in a patient with metastatic melanoma Open
Objective: To report a rare case of severe bilateral chorioretinopathy associated with ipilimumab in a patient with metastatic melanoma, highlighting the ocular toxicities that may arise from immune checkpoint inhibitors. Methods: A 38-yea…
View article: Correlation between renal function and OCTA parameters of the retina and choroid in early-stage diabetic patients
Correlation between renal function and OCTA parameters of the retina and choroid in early-stage diabetic patients Open
View article: Relation between systemic arteriosclerosis and choroidal blood flow in patients with acute coronary syndrome
Relation between systemic arteriosclerosis and choroidal blood flow in patients with acute coronary syndrome Open
Blood flow parameters in the optic nerve head are associated with systemic atherosclerosis, early renal dysfunction, and diastolic cardiac dysfunction in patients with acute coronary syndrome (ACS). This study aimed to investigate the rela…
View article: Retinal Organoid-Derived Exosomes Reduce CNV Lesion and Restore RPE Integrity in Mouse Laser-Induced Choroidal Neovascularization (CNV) Model
Retinal Organoid-Derived Exosomes Reduce CNV Lesion and Restore RPE Integrity in Mouse Laser-Induced Choroidal Neovascularization (CNV) Model Open
To address the shortcomings of existing anti-VEGF monotherapy in neovascular age-related macular degeneration (nAMD), we investigated the therapeutic capabilities of exosomes obtained from human induced pluripotent stem cell (hiPSC)-derive…
View article: Selective retina therapy for central serous chorioretinopathy with focal choroidal excavation: a retrospective case series of six eyes
Selective retina therapy for central serous chorioretinopathy with focal choroidal excavation: a retrospective case series of six eyes Open
Background We evaluated the clinical outcomes of selective retina therapy (SRT) in patients with central serous chorioretinopathy (CSC) who had nonconforming focal choroidal excavations (FCEs). Methods Among the 204 patients with chronic C…
View article: The Effect of Inferior Oblique Recession Surgery on Retinal and Choroidal Thickness in Pediatric Patients in a Single Center
The Effect of Inferior Oblique Recession Surgery on Retinal and Choroidal Thickness in Pediatric Patients in a Single Center Open
Objective: This study aimed to investigate the effect of inferior oblique recession (IOR) on retinal and choroidal thickness in pediatric patients. Methods: This retrospective study included 20 eyes that underwent IOR (operated group) and …
View article: Erythrocytic hemodynamics of human choriocapillaris observed by laser speckle flowgraphy: A case report
Erythrocytic hemodynamics of human choriocapillaris observed by laser speckle flowgraphy: A case report Open
Purpose: To report a case in which the hemodynamics of the choriocapillaris (CC) could be observed by tracking the blood flowing through a short posterior ciliary artery (SPCA) using laser speckle flowgraphy (LSFG). Observation: A 28-year-…
View article: Short-Term Effects of Intravitreal Ranibizumab Biosimilar Injections in Patients with Neovascular Age-Related Macular Degeneration on Retinal Nerve Fiber Layer Thickness
Short-Term Effects of Intravitreal Ranibizumab Biosimilar Injections in Patients with Neovascular Age-Related Macular Degeneration on Retinal Nerve Fiber Layer Thickness Open
Background/Objectives: Intravitreal anti–vascular endothelial growth factor (anti-VEGF) therapy is the standard treatment for neovascular age-related macular degeneration (nAMD), but concerns remain regarding its potential effects on optic…
View article: Three-Dimensional Choroidal Contour Mapping in Central Serous Chorioretinopathy and Fellow Eyes
Three-Dimensional Choroidal Contour Mapping in Central Serous Chorioretinopathy and Fellow Eyes Open
Studying choroidal surfaces helps understand how predispositions and compensatory mechanisms to venous overloading may differ in CSCR and fellow eyes and how contour changes may serve as a biomarker for the disease.
View article: Idiopathic Posterior Scleritis Complicated by Optic Perineuritis and Ocular Motility Disorder Successfully Controlled with Adalimumab: A Case Report
Idiopathic Posterior Scleritis Complicated by Optic Perineuritis and Ocular Motility Disorder Successfully Controlled with Adalimumab: A Case Report Open
Introduction: This report describes a rare case of idiopathic orbital inflammation with posterior scleritis complicated by optic perineuritis and ocular motility disorder. Case presentation: A 22-year-old woman presented with right ocular …
View article: Comparison of Three-Dimensional Choroidal Contour in Patients With Neovascular Age-Related Macular Degeneration and Their Fellow Eyes
Comparison of Three-Dimensional Choroidal Contour in Patients With Neovascular Age-Related Macular Degeneration and Their Fellow Eyes Open
The study of choroidal contour may help to understand the pathological changes in age-related macular degeneration.
View article: ASSESSMENT OF THE CORRELATIONAL RELATIONSHIP OF MORPHOFUNCTIONAL EYE PARAMETERS IN YOUNG PATIENTS WITH PROGRESSIVE MYOPIA
ASSESSMENT OF THE CORRELATIONAL RELATIONSHIP OF MORPHOFUNCTIONAL EYE PARAMETERS IN YOUNG PATIENTS WITH PROGRESSIVE MYOPIA Open
The prevalence of myopia, particularly high myopia, continues to increase and can lead to irreversible blindness. Objective. To evaluate the dynamics of axial length and choroidal thickness in eyes with different degrees of myopia and thei…
View article: Alterations of the vitreous pathology and anterior chamber angle structures following transscleral cyclophotocoagulation
Alterations of the vitreous pathology and anterior chamber angle structures following transscleral cyclophotocoagulation Open
AIM: To describe the alterations of the vitreous pathology and anterior chamber (AC) angle structures following transscleral cyclophotocoagulation (TSCP) and better understand the mechanism of post-laser intraocular pressure (IOP) reductio…
View article: Full-Spectrum Pachychoroid Manifestation in One Eye: A Case Report
Full-Spectrum Pachychoroid Manifestation in One Eye: A Case Report Open
Introduction: The pachychoroid spectrum refers to a group of chorioretinal disorders including pachychoroid pigment epitheliopathy (PPE), pachychoroid neovasculopathy (PNV), polypoidal choroidal vasculopathy (PCV), and central serous chori…
View article: Hyperreflective Choroidal Foci: A Comprehensive Review
Hyperreflective Choroidal Foci: A Comprehensive Review Open
Hyperreflective choroidal foci (HCF) are a finding on optical coherence tomography that may serve as a biomarker in various retinal and choroidal pathologies. These discrete hyperreflective spots, identified in various layers of the choroi…
View article: Abordaje diagnóstico multimodal de tumores coroideos en la consulta de oncología ocular de la Clínica Internacional de la Visión del Ecuador (CIVE)
Abordaje diagnóstico multimodal de tumores coroideos en la consulta de oncología ocular de la Clínica Internacional de la Visión del Ecuador (CIVE) Open
Background: choroidal tumors encompass a spectrum of benign and malignant lesions, including nevi, hemangiomas, and uveal melanomas. Diagnosis can be challenging, especially in early stages or when biopsy is unavailable. Multimodal imaging…
View article: Changes in Choriocapillaris Flow Deficits Before and After the Onset of Large Choroidal Hypertransmission Defects in AMD
Changes in Choriocapillaris Flow Deficits Before and After the Onset of Large Choroidal Hypertransmission Defects in AMD Open
CCFD values did not increase prior to the onset of hyperTDs with increases in CCFDs detected after their onset. These results suggest that loss of choriocapillaris perfusion did not precede hyperTD formation but may play a role in hyperTD …
View article: A comparative study of choroidal thickness and pigment epithelial detachment in acute and chronic central serous chorioretinopathy in Nepalese patients
A comparative study of choroidal thickness and pigment epithelial detachment in acute and chronic central serous chorioretinopathy in Nepalese patients Open
Background To study the significance and correlation of choroidal and retinal pigment epithelial changes with disease activity in Central Serous Chorioretinopathy (CSCR) eyes. Methods This was a retrospective analysis of clinical records a…
View article: Choroidal Mast Cells and Their Degranulation Are a Pivotal Trigger for Myopia Development
Choroidal Mast Cells and Their Degranulation Are a Pivotal Trigger for Myopia Development Open
Choroidal MC degranulation plays a critical role in LIM by promoting choroidal thinning and axial elongation. These findings enhance our understanding of the role of choroidal MC degranulation in myopia, suggesting a potential therapeutic …
View article: Wide-Field Choroidal Thickness Changes after Loading-Phase Anti-VEGF Therapy in Treatment- Naïve Neovascular AMD
Wide-Field Choroidal Thickness Changes after Loading-Phase Anti-VEGF Therapy in Treatment- Naïve Neovascular AMD Open
Purpose: While it is known that anti-vascular endothelial growth factor (anti-VEGF) treatment for neovascular age-related macular degeneration (nAMD) leads to a reduction in choroidal thickness in the macula, changes in peripheral choroida…
View article: The prechoroidal cleft in neovascular age‐related macular degeneration
The prechoroidal cleft in neovascular age‐related macular degeneration Open
The prechoroidal cleft is a lenticular, hypo‐reflective space on optical coherence tomography imaging, located between a band of fibrovascular material underneath the retinal pigment epithelium (RPE) and Bruch's membrane. It occurs in 8%–2…
View article: OCTA-based evaluation of the correlation between macular retinal and choroidal structural characteristics and refractive status in patients with retinopathy of prematurity
OCTA-based evaluation of the correlation between macular retinal and choroidal structural characteristics and refractive status in patients with retinopathy of prematurity Open
Purpose To investigate the correlation between macular retinal and choroidal structural characteristics and refractive status in preschool-aged children with retinopathy of prematurity (ROP), based on optical coherence tomography angiograp…
View article: Concurrent iridociliary adenoma and haemorrhagic uveal cysts causing rapid intraocular mass progression in a dog
Concurrent iridociliary adenoma and haemorrhagic uveal cysts causing rapid intraocular mass progression in a dog Open
A 6‐year‐old, mixed‐breed dog was referred for evaluation of a red, non‐painful right eye. Examination revealed a well‐circumscribed, lobulated, reddish mass in the anterior chamber, initially presumed to be a benign haematocyst. Despite t…
View article: Longitudinal changes in choroidal thickness in high myopia: Correlation with maculopathy progression and visual outcomes
Longitudinal changes in choroidal thickness in high myopia: Correlation with maculopathy progression and visual outcomes Open
Purpose To evaluate longitudinal changes in choroidal thickness (CT) in highly myopic eyes and their correlation with myopic maculopathy progression and visual outcomes. Methods Retrospective cohort study on 1228 eyes from 781 highly myopi…
View article: Idiopathic Choroidal Neovascularization in Young Adults: Report of Two Cases
Idiopathic Choroidal Neovascularization in Young Adults: Report of Two Cases Open
Idiopathic choroidal neovascularization (ICNV) is a rare but potentially vision-threatening condition occurring in patients under 50 years of age. Its etiology remains unclear, and the disease often affects the macular region, leading to s…
View article: Idiopathic Choroidal Neovascularization in Young Adults: Report of Two Cases
Idiopathic Choroidal Neovascularization in Young Adults: Report of Two Cases Open
Idiopathic choroidal neovascularization (ICNV) is a rare but potentially vision-threatening condition occurring in patients under 50 years of age. Its etiology remains unclear, and the disease often affects the macular region, leading to s…