Sophora flavescens
View article: Antibacterial Evaluation of Sophoraflavanone G from Sophora pachycarpa Against Pseudomonas aeruginosa and Staphylococcus epidermidis Biofilm
Antibacterial Evaluation of Sophoraflavanone G from Sophora pachycarpa Against Pseudomonas aeruginosa and Staphylococcus epidermidis Biofilm Open
Antimicrobial resistance, particularly among biofilm-forming pathogens, poses a serious threat to public health and drives the urgent need for new therapeutic agents. Sophoraflavanone G, a prenylated flavonoid derived from Sophora pachycar…
View article: Sophora flavescens-derived extracellular vesicles loaded with oncolytic vaccinia virus/IR1061 for NIR-II photoacoustic imaging guided multimodal treatment of diffuse large B-cell lymphoma
Sophora flavescens-derived extracellular vesicles loaded with oncolytic vaccinia virus/IR1061 for NIR-II photoacoustic imaging guided multimodal treatment of diffuse large B-cell lymphoma Open
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma, characterized by high heterogeneity and significant clinical challenges. Despite the widespread adoption of the R-CHOP regimen as the standard treatm…
View article: Antifungal Potential of Sophora flavescens Root Extract: HR-LCMS Analysis and Molecular Docking of Bioactive Compounds Against Nosocomial Fungal Pathogens
Antifungal Potential of Sophora flavescens Root Extract: HR-LCMS Analysis and Molecular Docking of Bioactive Compounds Against Nosocomial Fungal Pathogens Open
The increasing prevalence of multidrug-resistant (MDR) Candida infections emphasises the urgent need for novel antifungal agents. This study evaluates the antifungal properties of Sophora flavescens (S. flavescens) root extract against fiv…
View article: Potential Benefits and Side Effects of Sophora flavescens to Control Rachiplusia nu
Potential Benefits and Side Effects of Sophora flavescens to Control Rachiplusia nu Open
There is a global demand for reducing the adoption of traditional chemical insecticides in agriculture. Among the most promising alternatives, botanical insecticides have been increasingly gaining attention due to their efficacy combined w…
View article: Molecular mechanism underlying Oleum Cinnamomi-induced ferroptosis in MRSE via covalent modification of AhpC
Molecular mechanism underlying Oleum Cinnamomi-induced ferroptosis in MRSE via covalent modification of AhpC Open
Introduction: Oleum Cinnamomi (OC) is a volatile oil extracted by steam distillation from the dried branches and leaves of Cinnamomum cassia Presl, a plant belonging to the Lauraceae family. For centuries, OC has been utilized as a food pr…
View article: Investigate the Mechanism of Alkaloids of Sophora Flavescens for Co-Treatment of Lung Cancer and Liver Cancer
Investigate the Mechanism of Alkaloids of Sophora Flavescens for Co-Treatment of Lung Cancer and Liver Cancer Open
View article: Genes involved in the regulation of alkaloid and flavonoid biosynthesis in different tissues of Sophora tonkinensis via transcriptomics and metabolomics
Genes involved in the regulation of alkaloid and flavonoid biosynthesis in different tissues of Sophora tonkinensis via transcriptomics and metabolomics Open
This study offers a comprehensive analysis of the regulatory mechanisms governing alkaloid and flavonoid accumulation, as well as the associated key genes, across various S. tonkinensis tissues. These findings pave the way for future resea…
View article: Mortality of Rachiplusia nu (Guenée, 1852) (Lepidoptera: Noctuidae) Caused by Sophora flavescens Bioinsecticide and Its Selectivity to Trichogramma pretiosum (Riley, 1879) (Hymenoptera: Trichogrammatidae)
Mortality of Rachiplusia nu (Guenée, 1852) (Lepidoptera: Noctuidae) Caused by Sophora flavescens Bioinsecticide and Its Selectivity to Trichogramma pretiosum (Riley, 1879) (Hymenoptera: Trichogrammatidae) Open
There is a global demand for reducing the adoption of traditional chemical insecticides in agriculture. Among the most promising alternatives, botanical insecticides have gained increasingly attention due to their efficacy combined with a …
View article: Virtual screening, molecular dynamics simulations, and in vitro analysis of Sophora flavescens-derived aloperine against Haemonchus contortus
Virtual screening, molecular dynamics simulations, and in vitro analysis of Sophora flavescens-derived aloperine against Haemonchus contortus Open
Introduction The resistance of Haemonchus contortus to ivermectin (IVM) poses a significant economic threat to the global livestock industry. This necessitates alternative strategies for managing the development of drug resistance in H. co…
View article: Integrated Transcriptomic and Metabolomic Analysis Identified Key Transcriptional Factors Involved in Flavonoid and Alkaloid Biosynthesis Among Different Tissues of Sophora flavescens
Integrated Transcriptomic and Metabolomic Analysis Identified Key Transcriptional Factors Involved in Flavonoid and Alkaloid Biosynthesis Among Different Tissues of Sophora flavescens Open
Sophora flavescens has anti-inflammatory, analgesic, antibacterial, antiviral, and anti-tumor properties due to its active compounds, including alkaloids and flavonoids. Exploring the biosynthetic regulation mechanism of these compounds is…
View article: Antidiabetic Potential of Sophora Species: Mechanisms, Bioactive Constituents, and Therapeutic Prospects
Antidiabetic Potential of Sophora Species: Mechanisms, Bioactive Constituents, and Therapeutic Prospects Open
Diabetes is a major global health concern, and achieving optimal glycemic control remains a challenge for many patients. Despite the availability of current antidiabetic medications, about two-thirds of patients worldwide fail to achieve a…
View article: Ficha de Chaetobranchus flavescens
Ficha de Chaetobranchus flavescens Open
View article: Bioactive Molecules from Tropical American Plants: Potential Anti-Inflammatory Agents for Cytokine Storm Management
Bioactive Molecules from Tropical American Plants: Potential Anti-Inflammatory Agents for Cytokine Storm Management Open
The cytokine storm, a hyperinflammatory response characterized by the excessive release of pro-inflammatory mediators such as TNFα, INFγ, IL-1β, IL-6, and GM-CSF, has been identified as a critical factor in the progression and severity of …
View article: Dereplication of secondary metabolites from Sophora flavescens using an LC–MS/MS-based molecular networking strategy
Dereplication of secondary metabolites from Sophora flavescens using an LC–MS/MS-based molecular networking strategy Open
A dereplication strategy was developed for the screening of secondary metabolites from Sophora flavescens. The strategy consisted of 4 procedures. First, the extract of the Sophora flavescens root was subjected to LC-MS/MS analysis with bo…
View article: Desenvolvimento do percevejo-marrom Euschistus heros (Fabricius) em morangueiro e mortalidade com produto à base de Sophora flavescens
Desenvolvimento do percevejo-marrom Euschistus heros (Fabricius) em morangueiro e mortalidade com produto à base de Sophora flavescens Open
Euschistus heros é uma importante praga na cultura da soja e tem migrado para o morangueiro, causando injúrias, principalmente em pseudofrutos. Os objetivos deste trabalho foram determinar a capacidade de desenvolvimento de E. heros e caus…
View article: Delivery of Sophora flavescens Ait. using a dissolving microneedle enables enhanced psoriasis treatment
Delivery of Sophora flavescens Ait. using a dissolving microneedle enables enhanced psoriasis treatment Open
Objective: To assess the efficiency of a Sophora flavescens Ait (S. flavescens, Ku Shen)-soluble microneedle (SFA-MN) for improving skin lesion symptoms in mice with psoriasis. Methods: SFA-MNs were prepared using a two-mold molding proces…
View article: Dual effects of Camellia sinensis and Andrographis paniculata on hyperglycemia and infection in Drosophila
Dual effects of Camellia sinensis and Andrographis paniculata on hyperglycemia and infection in Drosophila Open
The coexistence of hyperglycemia and infectious diseases represents a critical global health challenge, particularly in resource-limited settings where it amplifies disease severity and complicates treatment approaches. Medicinal plants su…
View article: Efficient and Selective Extraction of Prenylated Flavonoids from Sophora flavescens Using Ultrasound-Assisted Hydrophobic Ionic Liquid and Characterization of Extraction Mechanism
Efficient and Selective Extraction of Prenylated Flavonoids from Sophora flavescens Using Ultrasound-Assisted Hydrophobic Ionic Liquid and Characterization of Extraction Mechanism Open
As a secondary metabolite with vigorous pharmacological activity (antitumor), prenylated flavonoids in Sophora flavescens (PFS) have great potential to be transformed into lead compounds. Its extraction has attracted more and more attentio…
View article: Ultrasound-assisted extraction of prenylated flavonoids from Sophora flavescens: Optimization, mechanistic characterization, antioxidant and anti-inflammatory activities
Ultrasound-assisted extraction of prenylated flavonoids from Sophora flavescens: Optimization, mechanistic characterization, antioxidant and anti-inflammatory activities Open
View article: Trifolirhizin: A Phytochemical with Multiple Pharmacological Properties
Trifolirhizin: A Phytochemical with Multiple Pharmacological Properties Open
Trifolirhizin is an important flavonoid glycoside reported from the roots of medicinal plants such as Astragalus membranaceus, Sophora tonkinensis, Ononis vaginalis, Euchresta formosana, Sophora Subprostrate, Ononis spinose, and Sophora fl…
View article: Explanation of the potential mechanism of <i>Sophora flavescens</i> Ait and processed products treating ulcerative colitis based on the analysis method of “chemical composition characterization-target prediction”
Explanation of the potential mechanism of <i>Sophora flavescens</i> Ait and processed products treating ulcerative colitis based on the analysis method of “chemical composition characterization-target prediction” Open
Screening of active ingredients and prediction of potential mechanisms of Sophora flavescens Ait and its processed products in the treatment of ulcerative colitis.
View article: Exploration of Capillary Electrophoresis Separation Mechanism for Alkaloids of Sophora Flavescens by Computer-aided Molecular Modeling
Exploration of Capillary Electrophoresis Separation Mechanism for Alkaloids of Sophora Flavescens by Computer-aided Molecular Modeling Open
View article: Research datas for the paper "The Chloroform portion of Sophora alopecuroides L. combos breast cancer resistance by targeting AKT1/CDK2"
Research datas for the paper "The Chloroform portion of Sophora alopecuroides L. combos breast cancer resistance by targeting AKT1/CDK2" Open
We discovered that the chloroform extracted from Sophora alopecuroides L. exhibited the capacity to counteract multidrug resistance in breast cancer significantly. However, the precise active ingredients and their underlying mechanisms of …
View article: Occurrence Download
Occurrence Download Open
A dataset containing 111344 species occurrences available in GBIF matching the query: { "and" : [ { "and" : [ "HasGeospatialIssue is false", "HasCoordinate is true", "OccurrenceStatus is Present", { "not" : { "BasisOfRecord" : [ "is one of…
View article: Occurrence Download
Occurrence Download Open
A dataset containing 423063 species occurrences available in GBIF matching the query: { "and" : [ { "and" : [ "HasGeospatialIssue is false", "HasCoordinate is true", "OccurrenceStatus is Present", { "not" : { "BasisOfRecord" : [ "is one of…
View article: Research datas for the paper "The Chloroform portion of Sophora alopecuroides L. combos breast cancer resistance by targeting AKT1/CDK2"
Research datas for the paper "The Chloroform portion of Sophora alopecuroides L. combos breast cancer resistance by targeting AKT1/CDK2" Open
We discovered that the chloroform extracted from Sophora alopecuroides L. exhibited the capacity to counteract multidrug resistance in breast cancer significantly. However, the precise active ingredients and their underlying mechanisms of …
View article: Genome-wide identification and expression analysis of the WRKY gene family in Sophora flavescens during tissue development and salt stress
Genome-wide identification and expression analysis of the WRKY gene family in Sophora flavescens during tissue development and salt stress Open
Sophora flavescens is a traditional Chinese medicinal herb rich in various bioactive secondary metabolites, such as alkaloids and flavonoids, and exhibits remarkable resistance to abiotic stress. The WRKY transcription factor (TF) family i…
View article: Four new flavonoids from <i>Sophora flavescens</i> and their antibacterial activities
Four new flavonoids from <i>Sophora flavescens</i> and their antibacterial activities Open
Three new flavanones sophoflavanone C (1), sophoflavanone D (2), sophoflavanone E (3), and one new flavanonol, sophoflavanone F (4), were isolated from the ethanol extract of the root bark of Sophora flavesce…
View article: Research Progress on the Anti-Breast Cancer Effect and Mechanism of Oxymatrine
Research Progress on the Anti-Breast Cancer Effect and Mechanism of Oxymatrine Open
Oxymatrine (OMT), an alkaloid derived from Sophora flavescens, possesses a diverse array of pharmacological activities, encompassing anti-inflammatory, antiviral, antitumor, and immune regulatory properties. In recent times, significant st…
View article: Meta-analysis of the effect of sophora flavescens on tumor metastasis-induced bone neuropathic pain
Meta-analysis of the effect of sophora flavescens on tumor metastasis-induced bone neuropathic pain Open
Background Tumor metastasis to bone is a critical and painful stage in cancer progression, significantly affecting patients’ quality of life. Traditional treatments for bone neuropathic pain often exhibit limited efficacy and undesirable s…