Portal hypertension
View article: Predictive value of subharmonic-aided pressure estimation for diagnosing clinically significant portal hypertension
Predictive value of subharmonic-aided pressure estimation for diagnosing clinically significant portal hypertension Open
View article: Role of non-invasive serological and CT imaging parameters in assessing portal hypertensive gastropathy severity
Role of non-invasive serological and CT imaging parameters in assessing portal hypertensive gastropathy severity Open
View article: Letter on ‘Clinical Features of Portal Hypertension and Their Prognostic Implications in Patients With Autoimmune Hepatitis’
Letter on ‘Clinical Features of Portal Hypertension and Their Prognostic Implications in Patients With Autoimmune Hepatitis’ Open
View article: Letter: Reinterpreting the Role of Microbiota‐Driven Nitric Oxide in Cirrhotic Portal Hypertension—A Maladaptive Compensatory Response?
Letter: Reinterpreting the Role of Microbiota‐Driven Nitric Oxide in Cirrhotic Portal Hypertension—A Maladaptive Compensatory Response? Open
View article: Risk factors and prediction model development for pancreatic fistula following splenectomy in Wilson’s disease patients with portal hypertension
Risk factors and prediction model development for pancreatic fistula following splenectomy in Wilson’s disease patients with portal hypertension Open
View article: Hepatic encephalopathy because of unusual portosystemic shunt
Hepatic encephalopathy because of unusual portosystemic shunt Open
Hepatic encephalopathy (HE) is a metabolic encephalopathy caused by liver failure and/or portosystemic shunting. A 68-year-old male developed HE and CT demonstrated cirrhosis and an unusual large portosystemic shunt between the umbilical a…
View article: Long-Term Outcomes and Bleeding Risk Factors in Pancreatic Portal Hypertension: A Retrospective Cohort Study
Long-Term Outcomes and Bleeding Risk Factors in Pancreatic Portal Hypertension: A Retrospective Cohort Study Open
Background: Pancreatic portal hypertension (PPH) is a distinct form of sinistral (left-sided) portal hypertension, primarily resulting from pancreatic diseases such as acute or chronic pancreatitis and pancreatic tumors. These condition…
View article: Navigating non-alcoholic fatty liver disease (NAFLD): understanding the correlation between hepatic vein and portal vein doppler indices and fatty liver grades
Navigating non-alcoholic fatty liver disease (NAFLD): understanding the correlation between hepatic vein and portal vein doppler indices and fatty liver grades Open
Objective: To determine the association of fatty liver ultrasound grade with hepatic venous waveform, hepatic vein damping index and portal vein pulsatility index. Method: The cross-sectional, prospective, analytical study was conducted at…
View article: Relevance of the Diagnostic Criteria for Diastolic Dysfunction in Patients With Transjugular Intrahepatic Portosystemic Shunt
Relevance of the Diagnostic Criteria for Diastolic Dysfunction in Patients With Transjugular Intrahepatic Portosystemic Shunt Open
Background & Aims Cirrhotic cardiomyopathy (CCM), particularly diastolic dysfunction (DD), often remains silent until stress occurs. Transjugular intrahepatic portosystemic shunt (TIPS) may unmask DD due to hemodynamic shifts. However, dat…
View article: Evaluation of portal venous flow velocity before and after direct acting antiviral therapy in chronic hepatitis C: A cohort study
Evaluation of portal venous flow velocity before and after direct acting antiviral therapy in chronic hepatitis C: A cohort study Open
This study aimed to evaluate the changes in portal venous flow velocity before and after direct-acting antiviral (DAA) therapy in patients diagnosed with chronic hepatitis C (CHC). A total of 53 CHC patients (36 males, 17 females; mean age…
View article: Retrospective analysis of risk factors for early recurrence after hepatocellular carcinoma resection
Retrospective analysis of risk factors for early recurrence after hepatocellular carcinoma resection Open
Objectives Early recurrence after surgical resection adversely affects long-term survival of hepatocellular carcinoma (HCC) patients. This study aims to develop and validate a novel predictive model for early recurrence of HCC after curati…
View article: A case of portal vein thrombosis due to cholecystitis: a 10-year follow-up case report
A case of portal vein thrombosis due to cholecystitis: a 10-year follow-up case report Open
We present a rare case of portal vein thrombosis (PVT) secondary to acute cholecystitis with a 10-year follow-up. A 62-year-old man presented with fever and epigastric pain and was diagnosed with acute cholecystitis. Cholecystitis is a rar…
View article: Cytopenias in Compensated Versus Decompensated Liver Function: Is There a Difference?
Cytopenias in Compensated Versus Decompensated Liver Function: Is There a Difference? Open
Background/Objectives: Patients with liver cirrhosis (LC) present hematological abnormalities with multiple etiologies. As liver function deteriorates, these abnormalities become more evident, conferring a higher risk of morbidity and mort…
View article: Acute upper gastrointestinal bleeding in the UK: 2022 audit update
Acute upper gastrointestinal bleeding in the UK: 2022 audit update Open
Background Acute upper gastrointestinal bleeding (AUGIB) is a common medical emergency with evolving demographics and management strategies, particularly in medical/endoscopic therapy and transfusion strategies. Objective To provide key da…
View article: Aortic stenosis in cirrhosis: Pathophysiology and management in the context of liver transplantation
Aortic stenosis in cirrhosis: Pathophysiology and management in the context of liver transplantation Open
Aortic stenosis (AS), a progressive disease affecting aortic valve function, is common among individuals with metabolic and degenerative conditions, and is notably challenging to manage in patients with cirrhosis. Patients with cirrhosis f…
View article: THE USE OF TRANSJUGULAR PORTOSYSTEMIC SHUNTS (TIPS) IN THE PROPHYLAXIS AND TREATMENT OF PORTAL HYPERTENSION SYNDROME: A BIBLIOGRAPHIC REVIEW
THE USE OF TRANSJUGULAR PORTOSYSTEMIC SHUNTS (TIPS) IN THE PROPHYLAXIS AND TREATMENT OF PORTAL HYPERTENSION SYNDROME: A BIBLIOGRAPHIC REVIEW Open
Introduction. Portal hypertension (PH) is a major hemodynamic consequence of chronic liver diseases and leads to significant morbidity and mortality due to complications such as variceal hemorrhage, refractory ascites, hydrothorax, hepator…
View article: 57-YEAR-OLD WOMAN WITH OESOPHAGEAL VARICES AND SUSPECTED NON- CIRRHOTIC PORTAL HYPERTENSION
57-YEAR-OLD WOMAN WITH OESOPHAGEAL VARICES AND SUSPECTED NON- CIRRHOTIC PORTAL HYPERTENSION Open
Non-cirrhotic portal hypertension (NCPH) is characterized by portal hypertension, splenomegaly, hypersplenism, and pancytopenia without histological evidence of cirrhosis. Causes include chronic infection, toxin exposure, thrombophilia, im…
View article: Association between preoperative platelet count and transjugular intrahepatic portosystemic shunt procedure-related hemorrhage in cirrhotic patients: a retrospective study
Association between preoperative platelet count and transjugular intrahepatic portosystemic shunt procedure-related hemorrhage in cirrhotic patients: a retrospective study Open
Objective Transjugular intrahepatic portosystemic shunt (TIPS) is a high-bleeding-risk vascular intervention. The association between TIPS-related hemorrhage and preprocedural platelet (PLT) count remains unclear. Methods This was a retros…
View article: Viatorr versus WallFlex stents in TIPS: A single-centre South African study
Viatorr versus WallFlex stents in TIPS: A single-centre South African study Open
Background: Transjugular intrahepatic portosystemic shunt (TIPS) procedures are vital in managing complications of portal hypertension. The Viatorr stent is the standard for TIPS, but availability constraints often necessitate the use of a…
View article: Budd Chiari Syndrome Secondary to Pernicious Anemia: An Acquired Thrombophilia
Budd Chiari Syndrome Secondary to Pernicious Anemia: An Acquired Thrombophilia Open
Budd-Chiari Syndrome (BCS) results from obstruction of hepatic venous outflow and is frequently linked to prothrombotic conditions. Acquired causes such as vitamin B12 deficiency anemia due to pernicious anemia remain underrecognized. We d…
View article: Assessing Venous Congestion in Acute and Chronic Heart Failure: A Review of Splanchnic, Cardiac and Pulmonary Ultrasound: Part 1: Conventional B-Mode, Colordoppler, and Vexus Protocol
Assessing Venous Congestion in Acute and Chronic Heart Failure: A Review of Splanchnic, Cardiac and Pulmonary Ultrasound: Part 1: Conventional B-Mode, Colordoppler, and Vexus Protocol Open
Background/Objectives: Heart failure (HF) causes systemic and regional haemodynamic alterations that extend beyond the heart, profoundly affecting splanchnic circulation. Venous congestion is a hallmark of heart failure (HF) and a major de…
View article: A Clinical Comprehensive Analysis of the Correlation between Decompensated Chronic Liver Disease in Portal Hypertensive Gastropathy and Diabetic Nephropathy
A Clinical Comprehensive Analysis of the Correlation between Decompensated Chronic Liver Disease in Portal Hypertensive Gastropathy and Diabetic Nephropathy Open
This is a case report of a 48-year-old male who presented with decompensated chronic liver disease, complicated by portal hypertensive gastropathy, diabetic nephropathy, and chronic kidney disease. He presented with symptoms of vomiting, f…
View article: Electrocardiographic T-Wave Changes in Patients with Liver Cirrhosis: A Marker of Decompensation
Electrocardiographic T-Wave Changes in Patients with Liver Cirrhosis: A Marker of Decompensation Open
Background: Cirrhotic cardiomyopathy is an underrecognized complication that affects nearly half of patients with liver cirrhosis. Electrocardiographic T-wave changes and diastolic dysfunction may serve as an early sign of cardiac involvem…
View article: Splenic Artery Aneurysm With Arterioportal Fistula: An Unusual Cause of Portal Hypertension
Splenic Artery Aneurysm With Arterioportal Fistula: An Unusual Cause of Portal Hypertension Open
Splenic artery aneurysms are uncommon vascular lesions. When associated with an arterioportal fistula, they may lead to portal hypertension due to abnormal shunting of arterial blood into the portal venous system. We describe the case of a…
View article: Characterizing Liver Cirrhosis: Clinical and Endoscopic Insights from a Tertiary Care Hospital
Characterizing Liver Cirrhosis: Clinical and Endoscopic Insights from a Tertiary Care Hospital Open
Liver cirrhosis, a major global health challenge, is characterized by irreversible liver damage, fibrosis, and the formation of abnormal nodules, contributing significantly to morbidity and mortality worldwide. Effective diagnosis and mana…
View article: Hepatic hypertension on-a-chip identifies GPR116 as a hydrostatic pressure mechanosensor to regulate vascular injury in cirrhosis
Hepatic hypertension on-a-chip identifies GPR116 as a hydrostatic pressure mechanosensor to regulate vascular injury in cirrhosis Open
Cirrhosis-associated portal hypertension drives vascular injury, yet the pathogenesis mediated by abnormal hydrostatic pressure (HP) remains unclear due to the absence of in vitro models replicating the cirrhotic perivascular mechanical mi…
View article: Clinically significant portal hypertension assessed by spleen stiffness measurement and its associated outcomes among people living with HIV/AIDS
Clinically significant portal hypertension assessed by spleen stiffness measurement and its associated outcomes among people living with HIV/AIDS Open
View article: Clinical indicators of liver regeneration after splenectomy in patients with cirrhotic Portal Hypertension
Clinical indicators of liver regeneration after splenectomy in patients with cirrhotic Portal Hypertension Open
Aim Laparoscopic splenectomy and esophagogastric devascularization (LSED) is a minimally invasive and effective approach for managing esophagogastric variceal bleeding (EVB) secondary to portal hypertension (PHT). The increased liver volum…
View article: One stone for two birds: Successful treatment of splenic artery aneurysm and gastric varices using endoscopic ultrasound-guided coil and glue embolization
One stone for two birds: Successful treatment of splenic artery aneurysm and gastric varices using endoscopic ultrasound-guided coil and glue embolization Open
View article: Characterizing Liver Cirrhosis: Clinical and Endoscopic Insights from a Tertiary Care Hospital
Characterizing Liver Cirrhosis: Clinical and Endoscopic Insights from a Tertiary Care Hospital Open
Liver cirrhosis, a major global health challenge, is characterized by irreversible liver damage, fibrosis, and the formation of abnormal nodules, contributing significantly to morbidity and mortality worldwide. Effective diagnosis an…