Alternative oxidase
View article: Expression of yeast NADH dehydrogenase and ascidian alternative oxidase affects metabolism and free radical processes in Drosophila
Expression of yeast NADH dehydrogenase and ascidian alternative oxidase affects metabolism and free radical processes in Drosophila Open
Objective: The study aimed to investigate the effect of overexpression of alternative mitochondrial enzymes such as yeast NADH dehydrogenase I (NDI1) and alternative oxidase (AOX) on the metabolism, oxidative stress and feeding behavior of…
View article: Improvement of Biocontrol Efficiency of Hanseniaspora thailandica Induced by Alginate Oligosaccharide Against Banana Anthracnose Caused by Colletotrichum musae
Improvement of Biocontrol Efficiency of Hanseniaspora thailandica Induced by Alginate Oligosaccharide Against Banana Anthracnose Caused by Colletotrichum musae Open
Banana anthracnose, caused by Colletotrichum musae, causes substantial postharvest losses worldwide, yet effective biocontrol remains limited. Although Hanseniaspora thailandica shows potential, its direct application provides inadequate c…
View article: The mitochondrial protein TMEM177 fine-tunes mammalian cytochrome c oxidase assembly
The mitochondrial protein TMEM177 fine-tunes mammalian cytochrome c oxidase assembly Open
The mitochondrial cytochrome c oxidase (COX, complex IV), a multi-subunit protein complex, plays a crucial role in cellular respiration by reducing oxygen to water and simultaneously pumping protons to enable oxidative phosphorylation (OXP…
View article: Functional analyses and integrated mechanisms of cellular destruction by L-amino acid oxidase
Functional analyses and integrated mechanisms of cellular destruction by L-amino acid oxidase Open
Snakebite accidents are prevalent worldwide and cause a spectrum of severe clinical manifestations and result in a reduction of patient quality of life and economic income. A major bottleneck in envenomation treatment is our limited unders…
View article: Molecular Identification of Some African and Asian Tephritid Fruit Flies (Diptera) Using Mitochondrial Cytochrome Oxidase 1
Molecular Identification of Some African and Asian Tephritid Fruit Flies (Diptera) Using Mitochondrial Cytochrome Oxidase 1 Open
Fruit flies of the family Tephritidae are among the most economically significant pests of horticultural crops worldwide, causing substantial losses in fruit production and trade. Accurate identification of species is crucial for effective…
View article: Cold plasma reduces the incidence of Botrytis cinerea infection in grape fruit by affecting the energy status and respiratory metabolism
Cold plasma reduces the incidence of Botrytis cinerea infection in grape fruit by affecting the energy status and respiratory metabolism Open
Table grapes possess thin skins and a high moisture content, making them particularly susceptible to mechanical damage and fungal infection during shipping and storage, leading to deterioration. Cold plasma (CP) technology is an innovative…
View article: Gene downregulation and photosynthetic disruption in Lactuca sativa under simulated microgravity and hypomagnetic field stress
Gene downregulation and photosynthetic disruption in Lactuca sativa under simulated microgravity and hypomagnetic field stress Open
View article: Assessing the function of the alternative electron transport chain in the <i>Cryptosporidium parvum</i> mitosome
Assessing the function of the alternative electron transport chain in the <i>Cryptosporidium parvum</i> mitosome Open
Cryptosporidium parvum and C. hominis possess a remanent mitochondrion called the mitosome, which lacks DNA, the tricarboxylic acid cycle, a conventional electron transport chain, and ATP synthesis. The mitosome retains ubiquinone and iron…
View article: Effector‐Mediated Spatial Reprogramming of Glycolate Oxidase Subverts Peroxisomal and Membrane‐Associated <scp>ROS</scp> Defences
Effector‐Mediated Spatial Reprogramming of Glycolate Oxidase Subverts Peroxisomal and Membrane‐Associated <span>ROS</span> Defences Open
Oomycete pathogens secrete hundreds of RXLR effectors into plant cells to modulate host immunity by targeting diverse plant proteins. Here, we report that the Peronophythora litchii RXLR effector PlAvh133 acts as a virulence factor and tar…
View article: NADPH Oxidase Isoform NOX-2 Deficiency Affects Mitochondrial Oxygen Consumption and Metabolic Flexibility
NADPH Oxidase Isoform NOX-2 Deficiency Affects Mitochondrial Oxygen Consumption and Metabolic Flexibility Open
View article: Functional Characterisation of Alternative Oxidase Protein Isoproteins in <scp> <i>Arabidopsis thaliana</i> </scp>
Functional Characterisation of Alternative Oxidase Protein Isoproteins in <span> <i>Arabidopsis thaliana</i> </span> Open
The Alternative Oxidase (AOX) is encoded by a small gene family in plants. While being one of the most intensively studied plant mitochondrial proteins, it is primarily only one isoform, AOX1a, that is well studied. We investigated the sub…
View article: Establishment of a low-temperature immersion method for extracting high-activity and high-purity mitochondria from Syntrichia caninervis Mitt.
Establishment of a low-temperature immersion method for extracting high-activity and high-purity mitochondria from Syntrichia caninervis Mitt. Open
Background Mitochondria are central to plant growth, development, and stress resilience. Despite their importance, mitochondrial research in desiccation-tolerant mosses remains underexplored. To unravel the stress resistance mechanisms of …
View article: Alternative Oxidase Enhances Metabolic Flexibility in Bioenergetic Metabolism of Physcomitrium patens
Alternative Oxidase Enhances Metabolic Flexibility in Bioenergetic Metabolism of Physcomitrium patens Open
View article: Chalkophore-mediated respiratory oxidase flexibility controls M. tuberculosis virulence
Chalkophore-mediated respiratory oxidase flexibility controls M. tuberculosis virulence Open
Oxidative phosphorylation has emerged as a critical therapeutic vulnerability of M. tuberculosis ( Mtb ). However, it is unknown how intracellular bacterial pathogens such as Mtb maintain respiration during infection despite the chemical e…
View article: Author response: The alternative oxidase reconfigures the larval mitochondrial electron transport system to accelerate growth and development in Drosophila melanogaster
Author response: The alternative oxidase reconfigures the larval mitochondrial electron transport system to accelerate growth and development in Drosophila melanogaster Open
View article: The alternative oxidase reconfigures the larval mitochondrial electron transport system to accelerate growth and development in Drosophila melanogaster
The alternative oxidase reconfigures the larval mitochondrial electron transport system to accelerate growth and development in Drosophila melanogaster Open
The alternative oxidase (AOX) is naturally present in the mitochondrial electron transfer system (ETS) of many organisms but absent in vertebrates and most insects. AOX oxidizes coenzyme Q and reduces O2 in H2O, partially replacing the ETS…
View article: Cytochrome c oxidase inactivation in <i>Physcomitrium patens</i> reveals that respiration coordinates plant metabolism
Cytochrome c oxidase inactivation in <i>Physcomitrium patens</i> reveals that respiration coordinates plant metabolism Open
Photosynthetic organisms use sunlight as an energy source but rely on respiration during the night and in nonphotosynthetic tissues. Respiration also occurs in photosynthetically active cells, where its role is still unclear due to the lac…
View article: The Alternative Oxidase Pathway Participates in Seagrass Seedling Establishment by Regulating Photosynthetic and Respiratory Metabolism
The Alternative Oxidase Pathway Participates in Seagrass Seedling Establishment by Regulating Photosynthetic and Respiratory Metabolism Open
The roles of the alternative oxidase (AOX) pathway in plant physiology and metabolism are of increasing interest. AOX was found to regulate the growth of Enhalus acoroides seedlings, but its specific mechanism and physiological significanc…
View article: ROS Signaling and NADPH Oxidase in Red Algae
ROS Signaling and NADPH Oxidase in Red Algae Open
We explore the diverse roles of reactive oxygen species (ROS) and NADPH oxidases in red algae, focusing on their involvement in fertilization, wound repair, stress adaptation, and development. Once considered mere metabolic byproducts, ROS…
View article: Comparison and Analysis of Resistance Differences in Alternaria alternata from Fungicides with Three Different Mechanisms
Comparison and Analysis of Resistance Differences in Alternaria alternata from Fungicides with Three Different Mechanisms Open
The pathogen Alternaria alternata infects a variety of plants and crops, notably poplars, and results in large financial losses. Using twelve chemical fungicides for fungicide sensitivity tests (FSTs) on A. alternata, the result showed tha…
View article: Impairment of Muscle Function Causes Pupal Lethality in Flies Expressing the Mitochondrial Alternative Oxidase
Impairment of Muscle Function Causes Pupal Lethality in Flies Expressing the Mitochondrial Alternative Oxidase Open
The mitochondrial alternative oxidase (AOX) from the tunicate Ciona intestinalis has been explored as a potential therapeutic enzyme for human mitochondrial diseases, yet its systemic effects remain poorly understood. Here, we investigate …
View article: The Regulatory Role of Exogenous Carnitine Applications in Lipid Metabolism, Mitochondrial Respiration, and Germination in Maize Seeds (Zea mays L.)
The Regulatory Role of Exogenous Carnitine Applications in Lipid Metabolism, Mitochondrial Respiration, and Germination in Maize Seeds (Zea mays L.) Open
The present study aimed to investigate the effects of exogenous carnitine treatments on maize seed germination by stimulating lipid metabolism and regulating the mitochondrial respiratory pathway. Maize seeds were grown as control, 5, 7.5,…
View article: Postharvest α‐lipoic acid treatment delayed the softening of strawberry fruit by regulating cell wall and energy metabolism
Postharvest α‐lipoic acid treatment delayed the softening of strawberry fruit by regulating cell wall and energy metabolism Open
After ripening, strawberry fruit is prone to softening, which seriously affects its commercial value. This study investigated the effects of α‐lipoic acid (α‐LA) treatment on firmness, cell wall metabolism, and energy metabolism of posthar…
View article: Heat stress during maturation of bovine oocytes profoundly impacts the mitochondrial bioenergetic profile and causes endoplasmic reticulum stress in subsequent blastocysts
Heat stress during maturation of bovine oocytes profoundly impacts the mitochondrial bioenergetic profile and causes endoplasmic reticulum stress in subsequent blastocysts Open
In dairy cows, detrimental effects of global warming and intensive genetic selection for high milk yield on reproductive performance have become increasingly relevant in cooler regions. Based on the current knowledge, we hypothesized that …
View article: Mitochondrial respiration defects in lymphoblast cell lines from patients with Dravet syndrome
Mitochondrial respiration defects in lymphoblast cell lines from patients with Dravet syndrome Open
Objective Dravet syndrome (DS) is a developmental and epileptic encephalopathy with early life intractable seizures and lifelong comorbidities. There is growing evidence linking energy metabolism to DS, from mitochondrial respiration defic…
View article: Bioenergetic metabolism restarts alongside germinant sensing and hydration in bacterial spore germination
Bioenergetic metabolism restarts alongside germinant sensing and hydration in bacterial spore germination Open
Bacterial spore germination transforms spores from dormant bodies to vegetative cells. Initiation of germination or spore rehydration can proceed without exogenous energy sources, so bioenergetic processes in germination have been overlook…
View article: Effects of marijuana and tobacco on male fertility and their relationship to genetic variation of mitochondrial cytochrome C oxidase genes
Effects of marijuana and tobacco on male fertility and their relationship to genetic variation of mitochondrial cytochrome C oxidase genes Open
Although tobacco smoking declined among men at reproductive age, the use of cannabis increased. The aim of our study was to determine the impact of tobacco and cannabis on sperm quality, sperm DNA integrity tested by Chromomycin A3 (CMA3) …
View article: AOX Affects the Synthesis of Polysaccharides by Regulating the Reactive Oxygen Species in Ganoderma lucidum
AOX Affects the Synthesis of Polysaccharides by Regulating the Reactive Oxygen Species in Ganoderma lucidum Open
Alternative oxidase (AOX) is a terminal oxidase in the mitochondrial electron transport chain that does not contribute to the generation of ATP. It plays a critical role in maintaining the balance between reactive oxygen species (ROS) prod…
View article: The HOPS and vCLAMP protein Vam6 connects polyphosphate with mitochondrial function and oxidative stress resistance in <i>Cryptococcus neoformans</i>
The HOPS and vCLAMP protein Vam6 connects polyphosphate with mitochondrial function and oxidative stress resistance in <i>Cryptococcus neoformans</i> Open
Cryptococcus neoformans is considered one of the most dangerous fungal threats to human health, and the World Health Organization recently ranked it in the critical priority group for perceived public health importance. Proliferation of C.…
View article: The alternative oxidase reconfigures the larval mitochondrial electron transport system to accelerate growth and development in <i>Drosophila melanogaster</i>
The alternative oxidase reconfigures the larval mitochondrial electron transport system to accelerate growth and development in <i>Drosophila melanogaster</i> Open
The alternative oxidase (AOX) is naturally present in the mitochondrial electron transfer system (ETS) of many organisms but absent in vertebrates and most insects. AOX oxidizes coenzyme Q and reduces O 2 in H 2 O, partially replacing the …