Remifentanil
View article: Intraoperative Nociception Monitoring Using the NoL Index: Phase-Specific Assessment of Nociceptive Responses During Spinal Surgery
Intraoperative Nociception Monitoring Using the NoL Index: Phase-Specific Assessment of Nociceptive Responses During Spinal Surgery Open
Background: Quantifying intraoperative nociceptive responses under general anesthesia remains challenging, particularly during complex procedures such as spinal surgery. The Nociception Level (NoL) index is a multiparametric tool designed …
View article: What are the benefits and risks of using combined regional and general anesthesia compared to general anesthesia alone in patients undergoing nephrectomy?
What are the benefits and risks of using combined regional and general anesthesia compared to general anesthesia alone in patients undergoing nephrectomy? Open
Combining regional with general anesthesia in nephrectomy can enhance postoperative pain management and reduce opioid consumption, though further research is warranted to understand comprehensive benefits and risks.
View article: What are the benefits and risks of using combined regional and general anesthesia compared to general anesthesia alone in patients undergoing nephrectomy?
What are the benefits and risks of using combined regional and general anesthesia compared to general anesthesia alone in patients undergoing nephrectomy? Open
Combining regional with general anesthesia in nephrectomy can enhance postoperative pain management and reduce opioid consumption, though further research is warranted to understand comprehensive benefits and risks.
View article: Efficacy of ultrasound-guided erector spinae plane block <i>versus</i> transversus abdominis plane block for intraoperative and postoperative pain control in total laparoscopic hysterectomy: results of the ARTEMIDE randomised controlled trial
Efficacy of ultrasound-guided erector spinae plane block <i>versus</i> transversus abdominis plane block for intraoperative and postoperative pain control in total laparoscopic hysterectomy: results of the ARTEMIDE randomised controlled trial Open
Laparoscopic hysterectomy (LH), one of the most common surgeries among women, results in moderate-to-severe postoperative pain. The use of the transversus abdominis plane (TAP) block for pain management in LH has been evaluated but with co…
View article: Research progress and future perspective in anaesthesiology
Research progress and future perspective in anaesthesiology Open
Anaesthesiology is evolving from a clinical-based discipline focused primarily on maintaining intraoperative safety into an evidence-based perioperative medicine that emphasizes comprehensive patient care throughout before, during and afte…
View article: Effect Of Ketamine Combined With Remifentanil On Analgesic Sedation And Inflammatory Factors In Severe Brain Injury
Effect Of Ketamine Combined With Remifentanil On Analgesic Sedation And Inflammatory Factors In Severe Brain Injury Open
Background: Severe brain injury patients often require effective analgesia and sedation to manage pain, agitation, and inflammatory responses, which can impact clinical outcomes. Objectives: This study aimed to analyze the effects of ketam…
View article: Effect of the index of consciousness 2 on intraoperative opioid dosage in ovarian cancer patients receiving neoadjuvant chemotherapy: a study protocol for a randomised controlled trial
Effect of the index of consciousness 2 on intraoperative opioid dosage in ovarian cancer patients receiving neoadjuvant chemotherapy: a study protocol for a randomised controlled trial Open
Introduction For ovarian cancer patients undergoing preoperative Neoadjuvant Chemotherapy (NACT), the toxicity of chemotherapeutic agents may cause hepatic and renal function impairment, altered sensitivity of the central nervous system or…
View article: Determining the Effective Dose of Oliceridine Compounded with Propofol for Painless Hysteroscopy: A Prospective Modified Dixon Sequential Dose-Finding Study
Determining the Effective Dose of Oliceridine Compounded with Propofol for Painless Hysteroscopy: A Prospective Modified Dixon Sequential Dose-Finding Study Open
View article: Factors Influencing Recovery After Total Intravenous Anaesthesia for Upper Gastrointestinal Endoscopy: A Single Center Prospective Observational Study
Factors Influencing Recovery After Total Intravenous Anaesthesia for Upper Gastrointestinal Endoscopy: A Single Center Prospective Observational Study Open
Objective: To identify patient- and clinical-level factors associated with recovery time after sedated GI endoscopy. Methodology: ASingle-centre prospective observational study was conducted at the Sindh Institute of Advanced Endoscopy and…
View article: Comparison of the safety and efficacy of desflurane versus sevoflurane on postoperative cognitive function and early recovery quality in elderly orthopedic patients: a prospective, randomized controlled trial
Comparison of the safety and efficacy of desflurane versus sevoflurane on postoperative cognitive function and early recovery quality in elderly orthopedic patients: a prospective, randomized controlled trial Open
Objective Desflurane is the most commonly suitable volatile anesthetic for elderly patients due to its low blood solubility, suggesting faster induction and awakening time. This study compared the safety and efficacy of desflurane versus s…
View article: Navigating Limited Physiologic Reserve: Risk-Adapted Anesthesia and Sympathetic Attenuation in a Septuagenarian with Advanced Cardiometabolic Multimorbidity
Navigating Limited Physiologic Reserve: Risk-Adapted Anesthesia and Sympathetic Attenuation in a Septuagenarian with Advanced Cardiometabolic Multimorbidity Open
Introduction: The aging surgical population presents a unique challenge characterized by "homeostenosis"—a depletion of physiologic reserve that renders patients vulnerable to perioperative stressors. This vulnerability is exacerbated by c…
View article: Effects of different anesthetics on remifentanil-induced postinfusion hyperalgesia in patients undergoing percutaneous endoscopic interlaminar discectomy: a randomized controlled trial
Effects of different anesthetics on remifentanil-induced postinfusion hyperalgesia in patients undergoing percutaneous endoscopic interlaminar discectomy: a randomized controlled trial Open
Background Continuous infusion of remifentanil during anesthesia potentially leads to remifentanil-induced postinfusion hyperalgesia (RPH), which may be regulated by anesthesia maintenance drugs. In this study, we investigated the effects …
View article: Capnography-detected respiratory depression during procedural sedation with remimazolam versus propofol: a randomised trial
Capnography-detected respiratory depression during procedural sedation with remimazolam versus propofol: a randomised trial Open
Remimazolam, a novel ultra-short-acting benzodiazepine, has gained attention for its favourable safety profile, particularly its reduced risk of respiratory depression compared to propofol during procedural sedation. However, previous stud…
View article: Remimazolam-Based Anesthetic Management in a Patient with Severe Aortic Stenosis and Myelodysplastic Syndrome-Related Thrombocytopenia: A Case Report
Remimazolam-Based Anesthetic Management in a Patient with Severe Aortic Stenosis and Myelodysplastic Syndrome-Related Thrombocytopenia: A Case Report Open
Background/Objectives: Severe aortic stenosis (AS) poses major anesthetic challenges because cardiac output is highly dependent on preload and heart rate, and abrupt afterload reduction or tachycardia may precipitate ischemia and cardiovas…
View article: Comparative effects of remimazolam and propofol on hemodynamic stability during sedation for painless gastroscopy: a randomized clinical trial
Comparative effects of remimazolam and propofol on hemodynamic stability during sedation for painless gastroscopy: a randomized clinical trial Open
View article: Physiological and Behavioral Effects of Continuous Remifentanil-Xylazine Administration in Donkeys
Physiological and Behavioral Effects of Continuous Remifentanil-Xylazine Administration in Donkeys Open
Kássia Fernanda Araújo Damasceno desenvolveu um estudo experimental voltado à avaliação dos efeitos comportamentais, sedativos e cardiorrespiratórios da infusão contínua de remifentanil associado à xilazina em jumentos nordestinos, protoco…
View article: Physiological and Behavioral Effects of Continuous Remifentanil-Xylazine Administration in Donkeys
Physiological and Behavioral Effects of Continuous Remifentanil-Xylazine Administration in Donkeys Open
Kássia Fernanda Araújo Damasceno desenvolveu um estudo experimental voltado à avaliação dos efeitos comportamentais, sedativos e cardiorrespiratórios da infusão contínua de remifentanil associado à xilazina em jumentos nordestinos, protoco…
View article: Comparison of Dexmedetomidine and Midazolam as Co-induction Agents to Propofol for Proseal Laryngeal Mask Airway Insertion: A Randomised Control Trial
Comparison of Dexmedetomidine and Midazolam as Co-induction Agents to Propofol for Proseal Laryngeal Mask Airway Insertion: A Randomised Control Trial Open
Introduction: The Laryngeal Mask Airway (LMA) is a supraglottic device designed to secure the airway during minor to moderate surgical procedures. Second-generation LMAs, such as the ProSeal LMA (PLMA), offer enhanced safety features, incl…
View article: Effects of electroacupuncture on the incidence of postoperative supraventricular arrhythmia and sleep quality in patients undergoing thoracoscopic surgery: a randomized controlled trial
Effects of electroacupuncture on the incidence of postoperative supraventricular arrhythmia and sleep quality in patients undergoing thoracoscopic surgery: a randomized controlled trial Open
Background Supraventricular arrhythmia and sleep disturbance frequently occur after thoracoscopic surgery for lung cancer. The present study is designed to evaluate the hypothesis that electroacupuncture is an effective treatment of suprav…
View article: ANESTHETIC NEUROPROTECTION: CURRENT EVIDENCE AND PERSPECTIVES IN THE MANAGEMENT OF NEUROLOGICAL SURGERIES
ANESTHETIC NEUROPROTECTION: CURRENT EVIDENCE AND PERSPECTIVES IN THE MANAGEMENT OF NEUROLOGICAL SURGERIES Open
Introduction: Perioperative neurological injury remains a major concern in neurosurgical anesthesia, where ischemia–reperfusion, oxidative stress, and inflammatory cascades may lead to irreversible neuronal damage. The concept of anestheti…
View article: The effect of continuous intravenous lidocaine infusion on postoperative analgesia in elderly patients undergoing laparoscopic colorectal surgery
The effect of continuous intravenous lidocaine infusion on postoperative analgesia in elderly patients undergoing laparoscopic colorectal surgery Open
View article: Barriers and enablers to sustainable anaesthetic practice: a mixed-methods study
Barriers and enablers to sustainable anaesthetic practice: a mixed-methods study Open
View article: Evolution of Pharmacologic Induction of Burst Suppression in Adult TBI: Barbiturate Coma Versus Modern Sedatives
Evolution of Pharmacologic Induction of Burst Suppression in Adult TBI: Barbiturate Coma Versus Modern Sedatives Open
Background: Severe traumatic brain injury (TBI) often leads to elevated intracranial pressure (ICP) that requires aggressive management. Inducing burst suppression with deep sedation is an established therapy for refractory intracranial hy…
View article: Remifentanil PCIA for labor analgesia: Does it work? Is it safe?
Remifentanil PCIA for labor analgesia: Does it work? Is it safe? Open
Background: Patient-controlled intravenous analgesia with remifentanil (RPCA) is increasingly considered as an alternative to epidural analgesia during labor. Its pharmacological profile—ultrashort half-life, rapid metabolism, and ease of …
View article: Comparação da analgesia pós-operatória em artroplastia de joelho: um estudo de coorte prospectivo
Comparação da analgesia pós-operatória em artroplastia de joelho: um estudo de coorte prospectivo Open
Esta pesquisa teve como objetivo comparar os diferentes métodos de analgesia utilizados em pacientes submetidos à artroplastia total do joelho (ATJ), com foco especial na associação de bloqueios periféricos pós-operatórios. Métodos: estudo…
View article: Characterization of sedation strategies in real-world use of pulsed field ablation Sub-analysis of the EU-PORIA registry.
Characterization of sedation strategies in real-world use of pulsed field ablation Sub-analysis of the EU-PORIA registry. Open
Background With the introduction of pulsed field ablation (PFA) to treat atrial fibrillation (AF), there is interest in studying workflow and sedation strategies to optimize integration into clinical practice. This sub-analysis characteriz…
View article: Comparison of Postoperative Analgesic Outcomes with Intravenous Midazolam and Dexmedetomidine in Patients Undergoing Abdominal Hysterectomy Under Spinal Anaesthesia
Comparison of Postoperative Analgesic Outcomes with Intravenous Midazolam and Dexmedetomidine in Patients Undergoing Abdominal Hysterectomy Under Spinal Anaesthesia Open
Background: Effective postoperative pain control remains a major challenge following abdominal hysterectomy performed under spinal anaesthesia. Sedative adjuvants such as dexmedetomidine and midazolam are commonly used to prolong analgesia…
View article: Anesthetic Management for an Urgent Artery Bypass Operation in A Patient with Severe Thrombocytopenia: A Case Report
Anesthetic Management for an Urgent Artery Bypass Operation in A Patient with Severe Thrombocytopenia: A Case Report Open
Severe thrombocytopenia poses a major anesthetic challenge due to high bleeding risk. We report an 81-year-old woman with myelodysplastic syndrome and refractory thrombocytopenia (<20,000/µL) requiring urgent iliac-to-mesenteric artery byp…
View article: Adequacy of Anesthesia Guidance Combined with Peribulbar Blocks Shows Potential Benefit in High-Risk PONV Patients Undergoing Vitreoretinal Surgeries
Adequacy of Anesthesia Guidance Combined with Peribulbar Blocks Shows Potential Benefit in High-Risk PONV Patients Undergoing Vitreoretinal Surgeries Open
Background/Objectives: Postoperative nausea and vomiting (PONV) are common after general anesthesia (GA) and, in patients undergoing vitreoretinal surgery, may be triggered by the oculocardiac reflex (OCR) leading to the oculoemetic reflex…
View article: Intravenous lidocaine infusion accelerates postoperative bowel function recovery in patients undergoing lumbar surgery: a multi-center, randomized controlled trial
Intravenous lidocaine infusion accelerates postoperative bowel function recovery in patients undergoing lumbar surgery: a multi-center, randomized controlled trial Open
Background: Lumbar surgery is often associated with significant postoperative pain, high opioid consumption, and delayed bowel function recovery. This study aimed to assess whether intravenous lidocaine infusion could enhance bowel functio…