Hypoglossal nerve
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Upper Airway Stimulation for Obstructive Sleep Apnea: Durability of the Treatment Effect at 18 Months Open
Upper airway stimulation via the hypoglossal nerve maintained a durable effect of improving airway stability during sleep and improved patient reported outcomes (Epworth Sleepiness Scale and Functional Outcomes of Sleep Questionnaire) with…
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Bilateral hypoglossal nerve stimulation for treatment of adult obstructive sleep apnoea Open
Background and aim Hypoglossal nerve stimulation (HNS) decreases obstructive sleep apnoea (OSA) severity via genioglossus muscle activation and decreased upper airway collapsibility. This study assessed the safety and effectiveness at 6 mo…
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Targeted hypoglossal nerve stimulation for the treatment of obstructive sleep apnea: Six‐month results Open
Objectives/Hypothesis This feasibility study was designed to show the preliminary safety and efficacy of targeted hypoglossal neurostimulation (THN), and to identify baseline predictors of successful therapy. Study Design Open‐label, prosp…
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Hypoglossal Nerve Stimulation in Adolescents With Down Syndrome and Obstructive Sleep Apnea Open
clinicaltrials.gov Identifier: NCT2344108.
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Masseteric Nerve Transfer for Facial Nerve Paralysis Open
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NEURAL CONTROL OF SWALLOWING Open
BACKGROUND: Swallowing is a motor process with several discordances and a very difficult neurophysiological study. Maybe that is the reason for the scarcity of papers about it. OBJECTIVE: It is to describe the chewing neural control and or…
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The Hypoglossal Nerve Stimulation as a Novel Therapy for Treating Obstructive Sleep Apnea—A Literature Review Open
Obstructive sleep apnea (OSA) is a common sleep disorder that affects all age groups and is associated with many co-morbid diseases (especially cardiovascular diseases). Continuous positive airway pressure (CPAP) is the gold standard for t…
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<span>Drug‐Induced</span> Sleep Endoscopy and Hypoglossal Nerve Stimulation Outcomes: A Multicenter Cohort Study Open
Objectives/Hypothesis To determine the association between findings of blinded reviews of preoperative drug‐induced sleep endoscopy (DISE) and outcomes of hypoglossal nerve stimulation (HNS) for obstructive sleep apnea (OSA). Study Design …
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Obstructive Sleep Apnea: Emerging Treatments Targeting the Genioglossus Muscle Open
Obstructive sleep apnea (OSA) is characterized by repetitive episodes of upper airway obstruction caused by a loss of upper airway dilator muscle tone during sleep and an inadequate compensatory response by these muscles in the context of …
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Hypoglossal nerve stimulation for obstructive sleep apnea: A review of the literature Open
Objective To review the indications and clinical evidence supporting hypoglossal nerve stimulation (HNS) therapy for the treatment of moderate‐to‐severe obstructive sleep apnea (OSA). Methods Peer reviewed literature on hypoglossal nerve s…
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Chemogenetic stimulation of the hypoglossal neurons improves upper airway patency Open
Obstructive sleep apnea (OSA) is characterized by recurrent upper airway obstruction during sleep. OSA leads to high cardiovascular morbidity and mortality. The pathogenesis of OSA has been linked to a defect in neuromuscular control of th…
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Upper Airway Stimulation for Obstructive Sleep Apnea: Past, Present, and Future Open
Obstructive sleep apnea (OSA) is an increasingly prevalent clinical problem with significant effects on both personal and public health. Continuous positive airway pressure (CPAP) has demonstrated excellent efficacy and low morbidity; long…
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Anatomic predictors of response and mechanism of action of upper airway stimulation therapy in patients with obstructive sleep apnea Open
These results suggest that smaller soft palate volumes at baseline and greater tongue movement anteriorly with stimulation improve the response to upper airway stimulation.
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The outcomes of hypoglossal nerve stimulation in the management of OSA: A systematic review and meta‐analysis Open
Objectives Obstructive sleep apnea (OSA) is a prevalent disease with significant health impacts. While first line therapy is CPAP, long‐term compliance is low and device misuse is common, highlighting the need for alternative therapies. Up…
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Hypoglossal Nerve Stimulation in the Treatment of Obstructive Sleep Apnea: Patient Selection and New Perspectives Open
Hypoglossal nerve stimulation (HNS) is an increasingly widespread OSA treatment. It is a non-anatomical modifying surgery able to achieve an adequate objective and subjective result with a reasonable complication rate. HNS exploits the neu…
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Hypoglossal Nerve Stimulator Implantation in an Adolescent With Down Syndrome and Sleep Apnea Open
Obstructive sleep apnea (OSA) is more common in children with Down syndrome, affecting up to 60% of patients, and may persist in up to 50% of patients after adenotonsillectomy. These children with persistent moderate to severe OSA require …
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Development of a Clinical Pathway and Technical Aspects of Upper Airway Stimulation Therapy for Obstructive Sleep Apnea Open
Obstructive sleep apnea (OSA) is a common disease with high morbidity and related mortality. Narrowing and collapse of the pharyngeal airway during sleep characterize the disease, resulting in a decrease (hypopnea) or a complete cessation …
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Evaluation of Hypoglossal Nerve Stimulation Treatment in Obstructive Sleep Apnea Open
Hypoglossal nerve stimulation demonstrated clinically significant improvements in obstructive sleep apnea severity, daytime sleepiness, and sleep-related quality of life in this pooled cohort of patient-level results. Age, body mass index,…
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Targeted Hypoglossal Nerve Stimulation for Patients With Obstructive Sleep Apnea Open
Importance Evidence is lacking from randomized clinical trials of hypoglossal nerve stimulation in obstructive sleep apnea (OSA). Objective To evaluate the safety and effectiveness of targeted hypoglossal nerve stimulation (THN) of the pro…
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Evaluation of Therapeutic Positive Airway Pressure as a Hypoglossal Nerve Stimulation Predictor in Patients With Obstructive Sleep Apnea Open
In this small prospective cohort study, therapeutic nasal PAP levels during DISE differed significantly between responder and nonresponders to HGNS. Because DISE represents a mandatory, relatively standardized diagnostic tool for HGNS cand…
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Transposition of the Intratemporal Facial to Hypoglossal Nerve for Reanimation of the Paralyzed Face Open
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Electroacupuncture Involved in Motor Cortex and Hypoglossal Neural Control to Improve Voluntary Swallowing of Poststroke Dysphagia Mice Open
The descending motor nerve conduction of voluntary swallowing is mainly launched by primary motor cortex (M1). M1 can activate and regulate peripheral nerves (hypoglossal) to control the swallowing. Acupuncture at “Lianquan” acupoint (CV23…
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Foramen magnum, occipital condyles and hypoglossal canals morphometry: anatomical study with clinical implications Open
The study confirmed that only specific HC dimensions showed side asymmetry (HCs maximum extracranial and minimum intracranial diameters and HCs length), gender dimorphism (HCs right length and left distance HC-OC posterior border) and age …
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Tumors Presenting as Multiple Cranial Nerve Palsies Open
Cranial nerve palsy could be one of the presenting features of underlying benign or malignant tumors of the head and neck. The tumor can involve the cranial nerves by local compression, direct infiltration or by paraneoplastic process. Cra…
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Silencing of Hypoglossal Motoneurons Leads to Sleep Disordered Breathing in Lean Mice Open
Obstructive Sleep Apnea (OSA) is a prevalent condition and a major cause of morbidity and mortality in Western Society. The loss of motor input to the tongue and specifically to the genioglossus muscle during sleep is associated with phary…
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Ultrasound appearance of peripheral nerves in the neck: vagus, hypoglossal and greater auricular Open
Background and aim. Information in ultrasonography about reference values of nerves, particularly of those located in the neck is limited. The aim of the study is to demonstrate the feasibility of direct visualization of the vagus, hypoglo…
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Implantation of the nyxoah bilateral hypoglossal nerve stimulator for obstructive sleep apnea Open
Objectives This report describes the surgical implantation of a novel bilateral hypoglossal nerve stimulator (Genio system®, Nyxoah S.A., Belgium) and the successful treatment of a patient with moderate obstructive sleep apnea (OSA). Study…
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Outcome of different facial nerve reconstruction techniques Open
Among various reanimation techniques, when indicated, direct end-to-side facial-hypoglossal anastomosis through epineural suturing is the most effective technique with excellent outcomes for facial reanimation and preservation of tongue mo…
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Development and Functional Organization of the Cranial Nerves in Lampreys Open
Lampreys, together with hagfishes, are the only extant representatives of the oldest branch of vertebrates, the agnathans, which are the sister group of gnathostomes; therefore, studies on these animals are of great evolutionary significan…
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Schwannoma of the hypoglossal nerve: Review of the literature based on an illustrative case Open
Schwannomas are benign tumours that originate from the myelin sheath of peripheral nerves. They are characterised by a slow growth tendency. Benign schwannomas represent 35% of the head and neck district tumours. Hypoglossal schwannomas ac…