Thrombolysis
View article: Epidemiological and Therapeutic Aspects of Acute Non-Traumatic Lower Limb Ischemia: A Retrospective Analysis of 50 Cases
Epidemiological and Therapeutic Aspects of Acute Non-Traumatic Lower Limb Ischemia: A Retrospective Analysis of 50 Cases Open
Acute non-traumatic ischemia of the lower limbs (ANLLI) remains a critical vascular emergency with a high risk of amputation and mortality if not diagnosed and treated promptly. The objective of this study was to analyze the epidemiologica…
View article: Prehospital intravenous access is associated with decreased door-to-computed tomography and door-to-intravenous thrombolysis time, but not door-to-endovascular therapy time
Prehospital intravenous access is associated with decreased door-to-computed tomography and door-to-intravenous thrombolysis time, but not door-to-endovascular therapy time Open
Introduction Prehospital stroke care can influence in-hospital stroke care, including facilitating earlier diagnosis and treatment. This study sought to determine the association between prehospital IV access and time to computed tomograph…
View article: Modern thrombolytic drugs in the treatment of myocardial infarction, pharmacoinvasive approach
Modern thrombolytic drugs in the treatment of myocardial infarction, pharmacoinvasive approach Open
Despite the successes of modern medicine, retains one of the leading positions in the causes of disability and mortality. In order to improve the prognosis of patients with acute myocardial infarction, reduce the focus of necrosis, and red…
View article: Administration of eptifibatide as rescue therapy during mechanical thrombectomy in acute ischemic stroke
Administration of eptifibatide as rescue therapy during mechanical thrombectomy in acute ischemic stroke Open
Background The success of the technical implementation of mechanical thrombectomy (MT) depends on many factors. Considering the experience of the interventional radiologist and the anatomical vascular differences of individual patients, it…
View article: Possibilities of prevention and treatment of deep vein thrombosis in the lower limbs after arrhythmia-related catheter interventions
Possibilities of prevention and treatment of deep vein thrombosis in the lower limbs after arrhythmia-related catheter interventions Open
Aim. To evaluate the methods used for therapeutic compression of complications and the use of anticoagulants during arrhythmia catheter interventions and in the early postoperative period at stages of thrombotic disease development and tre…
View article: Systemic inflammation–based hematological indices and 90-day functional outcomes after intravenous thrombolysis in acute ischemic stroke: a systematic review
Systemic inflammation–based hematological indices and 90-day functional outcomes after intravenous thrombolysis in acute ischemic stroke: a systematic review Open
Background Acute ischemic stroke (AIS) is one of the leading causes of mortality and long-term disability worldwide. Intravenous thrombolysis (IVT) with recombinant tissue plasminogen activator (rt-PA) remains the standard treatment for el…
View article: A bismuth-based nanoplatform with synergistic fibrin/NET disruption and antioxidant/anti-inflammatory capabilities for enhanced thrombolysis and prevention of deep vein thrombosis recurrence
A bismuth-based nanoplatform with synergistic fibrin/NET disruption and antioxidant/anti-inflammatory capabilities for enhanced thrombolysis and prevention of deep vein thrombosis recurrence Open
View article: Prehospital thrombolysis with tenecteplase in out-of-hospital cardiac arrest: a retrospective cohort study
Prehospital thrombolysis with tenecteplase in out-of-hospital cardiac arrest: a retrospective cohort study Open
View article: Analysis of 90-day risk factors for poor prognosis in patients with postoperative CT with hyperdense signs after thrombectomy for acute ischemic stroke
Analysis of 90-day risk factors for poor prognosis in patients with postoperative CT with hyperdense signs after thrombectomy for acute ischemic stroke Open
Objective To investigate the risk factors associated with poor 90-day prognosis in patients exhibiting hyperdense signs on the initial CT scan after mechanical thrombectomy for acute ischemic stroke. Methods We conducted a retrospective an…
View article: How effective are anticoagulants compared to thrombolytics in treating arterial thrombosis?
How effective are anticoagulants compared to thrombolytics in treating arterial thrombosis? Open
Anticoagulants are less effective for arterial thrombosis compared to thrombolytics, which dissolve clots and target platelet-rich thrombi, though thrombolytics bear higher bleeding risks.
View article: How effective are anticoagulants compared to thrombolytics in treating arterial thrombosis?
How effective are anticoagulants compared to thrombolytics in treating arterial thrombosis? Open
Anticoagulants are less effective for arterial thrombosis compared to thrombolytics, which dissolve clots and target platelet-rich thrombi, though thrombolytics bear higher bleeding risks.
View article: Clinical outcomes of endovascular therapy strategy based on thrombus location for acute superior mesenteric artery occlusion
Clinical outcomes of endovascular therapy strategy based on thrombus location for acute superior mesenteric artery occlusion Open
Purpose To evaluate the short-term outcomes of patients with acute superior mesenteric artery occlusion who underwent endovascular therapy using different endovascular techniques based on thrombus location. Materials and methods This singl…
View article: Clinical Outcomes and Treatment Strategies in Catastrophic High-Risk Pulmonary Embolism: A Retrospective Analysis
Clinical Outcomes and Treatment Strategies in Catastrophic High-Risk Pulmonary Embolism: A Retrospective Analysis Open
High-risk pulmonary embolism (PE) is a life-threatening condition characterized by hemodynamic instability, often leading to catastrophic outcomes such as cardiac arrest and cardiogenic shock. We conducted a retrospective analysis of patie…
View article: Tenecteplase Versus Alteplase for First‐Pass Reperfusion in Basilar Artery Occlusion Stroke Thrombectomy
Tenecteplase Versus Alteplase for First‐Pass Reperfusion in Basilar Artery Occlusion Stroke Thrombectomy Open
Objective The first‐pass effect (FPE), defined as excellent reperfusion after a single attempt, is associated with improved outcomes in large vessel occlusion stroke. We evaluated whether intravenous tenecteplase (TNK) compared with altepl…
View article: Dilemma in management of spontaneous neck hematoma
Dilemma in management of spontaneous neck hematoma Open
Spontaneous neck hematoma is a rare but potentially life-threatening condition due to its risk of rapid airway compromise. It is most commonly associated with aneurysm, infection, thyroid or parathyroid tumors, or underlying coagulopathy, …
View article: Subacute edema progression after acute ischemic stroke: impact of intravenous alteplase administration and reperfusion degree
Subacute edema progression after acute ischemic stroke: impact of intravenous alteplase administration and reperfusion degree Open
Introduction Alteplase is known to increase the risk of blood-brain barrier integrity disruption, potentiating hemorrhage and edema. Evolving edema reduces chances of good functional outcomes. There is a paucity of studies that investigate…
View article: Takotsubo syndrome with apical thrombosis associated with hyperthyroidism crisis: a case report from high-altitude Tibet
Takotsubo syndrome with apical thrombosis associated with hyperthyroidism crisis: a case report from high-altitude Tibet Open
Background Catecholamine surge is considered the primary trigger of Takotsubo syndrome(TTS), but its pathophysiological mechanisms remain incompletely understood. Cases of TTS with intracardiac thrombus induced by thyrotoxicosis in the set…
View article: Central retinal artery occlusion as a rare complication of trichoderma-associated acute invasive fungal sinusitis
Central retinal artery occlusion as a rare complication of trichoderma-associated acute invasive fungal sinusitis Open
This case underscores the need for early recognition of AIFRS in high-risk patients and systematic ophthalmic evaluation in cases of rapid vision loss. Multidisciplinary collaboration and cautious use of corticosteroids are critical. Inter…
View article: Balancing flow arrest and aspiration: The relationship between balloon guide catheters, large-bore aspiration, and first pass effect in mechanical thrombectomy
Balancing flow arrest and aspiration: The relationship between balloon guide catheters, large-bore aspiration, and first pass effect in mechanical thrombectomy Open
Background Balloon guide catheters (BGCs) have been associated with higher rates of first pass effect (FPE) in endovascular thrombectomy. Large-bore aspiration catheters (ACs) placed at the face of the embolus may mimic the flow arrest eff…
View article: Sex and Ethnic Disparities in Stroke Revascularisation Treatments and Post-Stroke Outcomes in Patients with Heart Failure: A National Inpatient Sample Study
Sex and Ethnic Disparities in Stroke Revascularisation Treatments and Post-Stroke Outcomes in Patients with Heart Failure: A National Inpatient Sample Study Open
Background/Objectives: We aimed to determine sex and racial/ethnic disparities in associations between Acute Ischaemic stroke (AIS) with co-morbid heart failure (HF) and in-hospital outcomes, using the US National Inpatient Sample (NIS) in…
View article: Impact of emergency nursing interventions on pre-hospital and in-hospital outcomes in acute ischemic stroke
Impact of emergency nursing interventions on pre-hospital and in-hospital outcomes in acute ischemic stroke Open
Objective Acute ischemic stroke (AIS) is a leading cause of mortality and long-term disability worldwide, with clinical outcomes highly dependent on the timeliness and coordination of emergency care. Emergency nurses are at the frontline o…
View article: OCT‐Guided Distal Left Main Bifurcation PCI: Mid‐Term Outcomes From a Multicenter South‐Asian Registry
OCT‐Guided Distal Left Main Bifurcation PCI: Mid‐Term Outcomes From a Multicenter South‐Asian Registry Open
Background Optical coherence tomography (OCT)‐guided percutaneous coronary intervention (PCI) enhances treatment of complex coronary artery lesions, including left main (LM) disease, by enabling lesion morphology assessment and stent optim…
View article: What is the risk of bleeding when using enoxaparin before thrombolysis in stroke patients?
What is the risk of bleeding when using enoxaparin before thrombolysis in stroke patients? Open
The evidence suggests that while enoxaparin may not significantly increase early bleeding risks in stroke patients undergoing thrombolysis, there is insufficient direct evidence to fully characterize its safety profile in this context.
View article: Efficacy and safety of edaravone dexborneol in acute large vessel occlusion patients with successful recanalization after endovascular treatment
Efficacy and safety of edaravone dexborneol in acute large vessel occlusion patients with successful recanalization after endovascular treatment Open
View article: What is the risk of bleeding when using enoxaparin before thrombolysis in stroke patients?
What is the risk of bleeding when using enoxaparin before thrombolysis in stroke patients? Open
The evidence suggests that while enoxaparin may not significantly increase early bleeding risks in stroke patients undergoing thrombolysis, there is insufficient direct evidence to fully characterize its safety profile in this context.
View article: Post-Ablation Stroke Despite NOAC Use: Successful Reperfusion Therapy After Dabigatran Reversal with Incidental Discovery of a Large MCA Aneurysm—A Case Report
Post-Ablation Stroke Despite NOAC Use: Successful Reperfusion Therapy After Dabigatran Reversal with Incidental Discovery of a Large MCA Aneurysm—A Case Report Open
Background: Catheter ablation is an established rhythm-control strategy for atrial fibrillation (AF), yet peri-procedural embolic stroke may still occur despite uninterrupted NOAC therapy. Case presentation: A 49-year-old woman on dabigatr…
View article: Comparative outcomes of ultrasound-assisted catheter-directed thrombolysis between patients with acute and acute-on-chronic pulmonary embolism
Comparative outcomes of ultrasound-assisted catheter-directed thrombolysis between patients with acute and acute-on-chronic pulmonary embolism Open
View article: No impact of intravenous thrombolysis on post thrombectomy transcranial Doppler pulsatility index
No impact of intravenous thrombolysis on post thrombectomy transcranial Doppler pulsatility index Open
Background While transcranial Doppler (TCD) studies are beneficial in evaluating macrovascular recanalization post mechanical thrombectomy (MT), they may have a role in estimating microvascular reperfusion. We aim to (1) evaluate if TCD-de…
View article: Histological analysis of thrombus composition in acute ischemic stroke with large vessel occlusion: impact of r-tPA treatment
Histological analysis of thrombus composition in acute ischemic stroke with large vessel occlusion: impact of r-tPA treatment Open
Background and purpose Mechanical thrombectomy advances enable detection of thrombus composition changes post-intravenous thrombolysis, but evidence remains limited. This study retrospectively analyzed thrombi obtained from mechanical thro…
View article: How is multiple ischemic stroke diagnosed and managed?
How is multiple ischemic stroke diagnosed and managed? Open
Multiple ischemic strokes require prompt diagnosis with imaging and management through thrombolytic therapy and secondary prevention measures. Variability in treatment protocols and approaches indicates an area for ongoing research and ref…