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Total-Body PET: Maximizing Sensitivity to Create New Opportunities for Clinical Research and Patient Care Open
PET is widely considered the most sensitive technique available for noninvasively studying physiology, metabolism, and molecular pathways in the living human being. However, the utility of PET, being a photon-deficient modality, remains co…
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First Human Imaging Studies with the EXPLORER Total-Body PET Scanner* Open
Within the EXPLORER Consortium, the construction of the world's first total-body PET/CT scanner has recently been completed. The 194-cm axial field of view of the EXPLORER PET/CT scanner is sufficient to cover, for the first time, the enti…
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Handbook of functional connectivity Magnetic Resonance Imaging methods in CONN Open
This handbook describes methods for processing and analyzing functional connectivity Magnetic Resonance Imaging (fcMRI) data using the CONN toolbox. The first chapter (fMRI minimal preprocessing pipeline) describes standard and advanced pr…
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Intraoral Scanner Technologies: A Review to Make a Successful Impression Open
To overcome difficulties associated with conventional techniques, impressions with IOS (intraoral scanner) and CAD/CAM (computer-aided design and manufacturing) technologies were developed for dental practice. The last decade has seen an i…
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Validation of A Method to Compensate Multicenter Effects Affecting CT Radiomics Open
Background Radiomics extracts features from medical images more precisely and more accurately than visual assessment. However, radiomics features are affected by CT scanner parameters such as reconstruction kernel or section thickness, thu…
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Performance Evaluation of the uEXPLORER Total-Body PET/CT Scanner Based on NEMA NU 2-2018 with Additional Tests to Characterize PET Scanners with a Long Axial Field of View Open
The world's first total-body PET scanner with an axial field of view (AFOV) of 194 cm is now in clinical and research use at our institution. The uEXPLORER PET/CT system is the first commercially available total-body PET scanner. Here we p…
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Forest Inventory with Terrestrial LiDAR: A Comparison of Static and Hand-Held Mobile Laser Scanning Open
The application of static terrestrial laser scanning (TLS) in forest inventories is becoming more effective. Nevertheless, the occlusion effect is still limiting the processing efficiency to extract forest attributes. The use of a mobile l…
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Real-time motion analytics during brain MRI improve data quality and reduce costs Open
Head motion systematically distorts clinical and research MRI data. Motion artifacts have biased findings from many structural and functional brain MRI studies. An effective way to remove motion artifacts is to exclude MRI data frames affe…
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Performance Characteristics of the Biograph Vision Quadra PET/CT System with a Long Axial Field of View Using the NEMA NU 2-2018 Standard Open
Our purpose was to evaluate the performance of the Biograph Vision Quadra PET/CT system. This new system is based on the Biograph Vision 600, using the same silicon photomultiplier-based detectors with 3.2 × 3.2 × 20 mm lutetium-oxoorthosi…
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7 Tesla MRI of the ex vivo human brain at 100 micron resolution Open
We present an ultra-high resolution MRI dataset of an ex vivo human brain specimen. The brain specimen was donated by a 58-year-old woman who had no history of neurological disease and died of non-neurological causes. After fixation in 10%…
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Calibration of fringe projection profilometry: A comparative review Open
Fringe projection profilometry is widely used for three-dimensional (3D) measurements. System calibration is crucial to fringe projection systems, since it determines how the phase is converted into 3D geometry. Many methods and studies on…
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Standardized Assessment of Automatic Segmentation of White Matter Hyperintensities and Results of the WMH Segmentation Challenge Open
Quantification of cerebral white matter hyperintensities (WMH) of presumed vascular origin is of key importance in many neurological research studies. Currently, measurements are often still obtained from manual segmentations on brain MR i…
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Estimating CT Image From MRI Data Using Structured Random Forest and Auto-Context Model Open
Computed tomography (CT) imaging is an essential tool in various clinical diagnoses and radiotherapy treatment planning. Since CT image intensities are directly related to positron emission tomography (PET) attenuation coefficients, they a…
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Detector-based spectral CT with a novel dual-layer technology: principles and applications Open
Detector-based spectral computed tomography is a novel dual-energy CT technology that employs two layers of detectors to simultaneously collect low- and high-energy data in all patients using standard CT protocols. In addition to the conve…
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A Guide to ComBat Harmonization of Imaging Biomarkers in Multicenter Studies Open
The impact of PET image acquisition and reconstruction parameters on SUV measurements or radiomic feature values is widely documented. This scanner effect is detrimental to the design and validation of predictive or prognostic models and l…
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Automatic Targetless Extrinsic Calibration of a 3D Lidar and Camera by Maximizing Mutual Information Open
This paper reports on a mutual information (MI) based algorithm for automatic extrinsic calibration of a 3D laser scanner and optical camera system. By using MI as the registration criterion, our method is able to work in situ without the …
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Accuracy of complete- and partial-arch impressions of actual intraoral scanning systems in vitro Open
Within the limitations of this study, digital impressions obtained from specific IOSs are a valid alternative to conventional impressions for partial-arch segments. Complete-arch impressions are still challenging for IOS devices; however, …
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Low‐cost and portable MRI Open
Research in MRI technology has traditionally expanded diagnostic benefit by developing acquisition techniques and instrumentation to enable MRI scanners to "see more." This typically focuses on improving MRI's sensitivity and spatiotempora…
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NEMA NU 2-2012 performance studies for the SiPM-based ToF-PET component of the GE SIGNA PET/MR system Open
Performance measurements of the ToF-PET whole body GE SIGNA PET/MR system indicate that it is a promising new simultaneous imaging platform.
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Clinical Study of the Influence of Ambient Light Scanning Conditions on the Accuracy (Trueness and Precision) of an Intraoral Scanner Open
Purpose To quantify the impact of ambient lighting conditions on the accuracy (trueness and precision) of an intraoral scanner (IOS) when maxillary complete‐arch and maxillary right quadrant digital scans were performed in a patient. Mater…
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Pixel-wise absolute phase unwrapping using geometric constraints of structured light system Open
This paper presents a method to unwrap phase pixel by pixel by solely using geometric constraints of the structured light system without requiring additional image acquisition or another camera. Specifically, an artificial absolute phase m…
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A review of the use of terrestrial laser scanning application for change detection and deformation monitoring of structures Open
Change detection and deformation monitoring is an active area of research within the field of engineering surveying as well as overlapping areas such as structural and civil engineering. The application of Terrestrial Laser Scanning (TLS) …
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Subtle in-scanner motion biases automated measurement of brain anatomy from in vivo MRI Open
While the potential for small amounts of motion in functional magnetic resonance imaging (fMRI) scans to bias the results of functional neuroimaging studies is well appreciated, the impact of in-scanner motion on morphological analysis of …
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A low-cost and shielding-free ultra-low-field brain MRI scanner Open
Magnetic resonance imaging is a key diagnostic tool in modern healthcare, yet it can be cost-prohibitive given the high installation, maintenance and operation costs of the machinery. There are approximately seven scanners per million inha…
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Towards MRI-Based Autonomous Robotic US Acquisitions: A First Feasibility Study Open
Robotic ultrasound has the potential to assist and guide physicians during interventions. In this work, we present a set of methods and a workflow to enable autonomous MRI-guided ultrasound acquisitions. Our approach uses a structured-ligh…
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From Laser Scanning to Finite Element Analysis of Complex Buildings by Using a Semi-Automatic Procedure Open
In this paper, a new semi-automatic procedure to transform three-dimensional point clouds of complex objects to three-dimensional finite element models is presented and validated. The procedure conceives of the point cloud as a stacking of…
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Fast optical-resolution photoacoustic microscopy using a 2-axis water-proofing MEMS scanner Open
Optical-resolution photoacoustic microscopy (OR-PAM) is a novel label-free microscopic imaging tool to provide in vivo optical absorbing contrasts. Specially, it is crucial to equip a real-time imaging capability without sacrificing high s…
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Total-Body Dynamic Reconstruction and Parametric Imaging on the uEXPLORER Open
The world's first 194-cm-long total-body PET/CT scanner (uEXPLORER) has been built by the EXPLORER Consortium to offer a transformative platform for human molecular imaging in clinical research and health care. Its total-body coverage and …
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Trueness and Precision of Four Intraoral Scanners in Oral Implantology: A Comparative in Vitro Study Open
Although no differences in trueness and precision were found between partially and totally edentulous models, statistically significant differences were found between the different scanners. Further studies are required to confirm these re…
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Motion‐related artifacts in structural brain images revealed with independent estimates of in‐scanner head motion Open
Motion‐contaminated T1‐weighted (T1w) magnetic resonance imaging (MRI) results in misestimates of brain structure. Because conventional T1w scans are not collected with direct measures of head motion, a practical alternative is needed to i…