Leptospira
View article: Whole genome sequencing as a reliable alternative for Salmonella serotyping: a comparative study with the gold-standard method
Whole genome sequencing as a reliable alternative for Salmonella serotyping: a comparative study with the gold-standard method Open
Introduction Salmonella is a major foodborne pathogen of significant global health concern, leading to conditions like gastroenteritis, with symptoms such as diarrhea, abdominal cramps, and fever. Although most cases are self-limiting, Sal…
View article: Leptospirosis with Severe Acute Kidney Injury & Jaundice: A Review of 2 Cases
Leptospirosis with Severe Acute Kidney Injury & Jaundice: A Review of 2 Cases Open
Introduction: Leptospirosis is a zoonosis of global significance due to infection with Leptospira spp., a motile, obligate aerobic, spiral bacteria from contaminated soil, water or rat urine. This infection may have variable and protean ma…
View article: PREreview of "Molecular detection and genetic characterisation of a large flood-borne outbreak of human leptospirosis in Jakarta, Indonesia: a retrospective analysis of surveillance data"
PREreview of "Molecular detection and genetic characterisation of a large flood-borne outbreak of human leptospirosis in Jakarta, Indonesia: a retrospective analysis of surveillance data" Open
This Zenodo record is a permanently preserved version of a PREreview. You can view the complete PREreview at https://prereview.org/reviews/17707064. Summary This study investigated a large leptospirosis outbreak in Jakarta, Indonesia. A to…
View article: A Guidance for Diagnosis, Control Measures, and Surveillance of Leptospirosis in Non‐Human Primates From a Veterinary Perspective in a One‐Health Approach
A Guidance for Diagnosis, Control Measures, and Surveillance of Leptospirosis in Non‐Human Primates From a Veterinary Perspective in a One‐Health Approach Open
Leptospirosis is an emerging zoonotic disease caused by pathogenic Leptospira spp., affecting a wide range of domestic and wild mammals including nonhuman primates ( NHPs ). Despite rising incidence rates in both NHPs and humans, there is …
View article: PREreview of "Molecular detection and genetic characterisation of a large flood-borne outbreak of human leptospirosis in Jakarta, Indonesia: a retrospective analysis of surveillance data"
PREreview of "Molecular detection and genetic characterisation of a large flood-borne outbreak of human leptospirosis in Jakarta, Indonesia: a retrospective analysis of surveillance data" Open
This Zenodo record is a permanently preserved version of a PREreview. You can view the complete PREreview at https://prereview.org/reviews/17707064. Summary This study investigated a large leptospirosis outbreak in Jakarta, Indonesia. A to…
View article: Health Literacy Gaps in Leptospirosis Prevention: Evidence from an Analysis of Knowledge, Attitudes, Practices, and Perceptions in Limboto Lake, Gorontalo
Health Literacy Gaps in Leptospirosis Prevention: Evidence from an Analysis of Knowledge, Attitudes, Practices, and Perceptions in Limboto Lake, Gorontalo Open
In Indonesia, leptospirosis is a zoonotic disease with rats as the main reservoir that remains a serious public health problem, especially in areas with high prevalence, including Lake Limboto and Gorontalo. The purpose of this study was t…
View article: Hotspots of Infection: Spatial Analysis of Rat Populations and Leptospira sp. in South Sulawesi
Hotspots of Infection: Spatial Analysis of Rat Populations and Leptospira sp. in South Sulawesi Open
Leptospirosis is a zoonotic disease caused by the bacterium Leptospira sp., primarily transmitted through the urine of infected rodents. The objective of this research is to analyze the spatial distribution of rat populations and to detect…
View article: Evaluation of the conserved subunit of the pathogenic <i>Leptospira</i> FlaB protein-based immunochromatographic test for the diagnosis of acute leptospirosis
Evaluation of the conserved subunit of the pathogenic <i>Leptospira</i> FlaB protein-based immunochromatographic test for the diagnosis of acute leptospirosis Open
We have computationally identified a conserved region of flagellin B (FlaB) protein that is present only in pathogenic Leptospira but absent in non-pathogenic Leptospira or other flagellated bacteria. The predicted FlaB subunit protein (sF…
View article: Leptospirosis seroprevalence and exposure factors in three informal settlements of French Guiana: An opportunistic survey
Leptospirosis seroprevalence and exposure factors in three informal settlements of French Guiana: An opportunistic survey Open
Background Leptospirosis is a zoonotic disease of increasing importance in French Guiana. It particularly affects subjects living in precarious conditions. We aimed to determine the seroprevalence and the risk of exposure to leptospirosis …
View article: Aborto en ganado de carne en Uruguay
Aborto en ganado de carne en Uruguay Open
La leptospirosis es una reconocida zoonosis bacteriana causada por Leptospira spp. En bovinos, su ocurrencia suele estar más vinculada a afecciones reproductivas. Este estudio pretende determinar la asociación del aborto con la seropositiv…
View article: A penny for your CSF - An Unexpected consequence of bottle recycling: Meningitis due to Leptospira and Streptococcus – a case report
A penny for your CSF - An Unexpected consequence of bottle recycling: Meningitis due to Leptospira and Streptococcus – a case report Open
Background Leptospirosis is a preventable zoonotic infection that can present with a wide spectrum of clinical features, ranging from mild flu-like illness to severe multi-organ dysfunction. Meningitis due to Leptospira is rare, and co-inf…
View article: Complement C3 deficiency enhances renal leptospiral load and inflammation while impairing T cell differentiation during chronic <i>Leptospira interrogans</i> infection
Complement C3 deficiency enhances renal leptospiral load and inflammation while impairing T cell differentiation during chronic <i>Leptospira interrogans</i> infection Open
Leptospirosis is a neglected disease caused by pathogenic Leptospira spp., affecting an estimated 1 million people annually and resulting in approximately 60,000 deaths. The disease can lead to hepatic, renal, and pulmonary dysfunctions an…
View article: The Prevalence of Leptospira antibodies among dog handlers in Jos South and Kanke L.G.As, Plateau State
The Prevalence of Leptospira antibodies among dog handlers in Jos South and Kanke L.G.As, Plateau State Open
View article: Five Leptospira spp. Antibody Point-of-Care Tests in Healthy Dogs Reveal Different Results After Revaccination Against Leptospirosis
Five Leptospira spp. Antibody Point-of-Care Tests in Healthy Dogs Reveal Different Results After Revaccination Against Leptospirosis Open
The microscopic agglutination test (MAT) is the diagnostic standard for canine leptospirosis. However, it is a time-consuming process and does not differentiate between infection- and vaccine-induced antibodies. Canine Leptospira spp.-spec…
View article: Monosaccharide Profiling of Lipopolysaccharide: A Novel Approach for Identification of Antigenically Similar Leptospira and Its One Health Implications
Monosaccharide Profiling of Lipopolysaccharide: A Novel Approach for Identification of Antigenically Similar Leptospira and Its One Health Implications Open
View article: Host-specific immune responses against Leptospira spp 3638
Host-specific immune responses against Leptospira spp 3638 Open
Description Leptospira interrogans is the major causative agent of leptospirosis. Rodents are considered the most important reservoir of Leptospira. Infected rodents are asymptomatic carriers in which bacteria colonize the kidneys and are …
View article: Commentary on: Serosurvey, cultural, and molecular detection of circulating Leptospira spp. in different animals in selected areas of Bangladesh
Commentary on: Serosurvey, cultural, and molecular detection of circulating Leptospira spp. in different animals in selected areas of Bangladesh Open
View article: Culture-negative bacteria: a blind spot in bacterial pathogen prioritization
Culture-negative bacteria: a blind spot in bacterial pathogen prioritization Open
Culture-negative bacteria (CNB), including Bartonella spp., Coxiella burnetii, Rickettsia spp., Orientia tsutsugamushi, and Leptospira spp., are frequent yet underrecognized causes of febrile illness in low- and middle-income countries (LM…
View article: Molecular Detection and Characterization of Leptospira spp. in Rodents from Different Habitats in Mgeta Ecosystem, Morogoro - Tanzania
Molecular Detection and Characterization of Leptospira spp. in Rodents from Different Habitats in Mgeta Ecosystem, Morogoro - Tanzania Open
Background: Leptospirosis, a neglected zoonotic disease caused by Leptospira spp., poses a major public health threat in tropical regions, including Tanzania. Rodents are the principal reservoirs responsible for environmental contamination…
View article: Seropositivity for Pathogenic Leptospira in Dogs, Cats, and Horses at a Teaching Veterinary Hospital in Southern Chile
Seropositivity for Pathogenic Leptospira in Dogs, Cats, and Horses at a Teaching Veterinary Hospital in Southern Chile Open
At a veterinary hospital in southern Chile, we conducted an epidemiological study involving domestic dogs, cats, and horses to determine the seropositivity for pathogenic Leptospira spp., identify the infecting serogroups, measure antibody…
View article: Detection of leptospiral antibodies and DNA in freshwater fish
Detection of leptospiral antibodies and DNA in freshwater fish Open
Leptospirosis is an important zoonotic disease that is maintained in populations due to chronic kidney infection of reservoir mammals. Previous work from our lab has identified rodents, voles, shrews, chipmunks and several species of amphi…
View article: Whole Genome Characterization of Leptospira kirschneri Serogroup Pomona in Croatia: Insights into Its Diversity and Evolutionary Emergence
Whole Genome Characterization of Leptospira kirschneri Serogroup Pomona in Croatia: Insights into Its Diversity and Evolutionary Emergence Open
Leptospirosis is a worldwide zoonosis caused by pathogenic Leptospira spp. with small rodents serving as the main reservoir. In Croatia, the serogroup Pomona has been detected most frequently, but its genomic diversity remains insufficient…
View article: Epidemiological, temporal, and geographic trends of leptospirosis in the United States, 2014–2020
Epidemiological, temporal, and geographic trends of leptospirosis in the United States, 2014–2020 Open
Background Leptospirosis, caused by pathogenic Leptospira spp., is one of the most widespread zoonotic diseases globally. In 2014, leptospirosis was reinstated as a nationally notifiable condition due to evidence of increasing incidence an…
View article: The ClpA chaperone and the two adaptor proteins modulate the fate of the model substrate tagged with a SsrA-degron of <i>Leptospira</i>
The ClpA chaperone and the two adaptor proteins modulate the fate of the model substrate tagged with a SsrA-degron of <i>Leptospira</i> Open
Bacterial caseinolytic protease (Clp) chaperone–protease complexes are essential for the degradation of misfolded and aggregated protein substrates. The spirochaete Leptospira interrogans possesses a set of Clp adaptor proteins (ClpS1 and …
View article: Correction: Designing adjuvant formulations to promote immunogenicity and protective efficacy of Leptospira immunoglobulin-like protein a subunit vaccine
Correction: Designing adjuvant formulations to promote immunogenicity and protective efficacy of Leptospira immunoglobulin-like protein a subunit vaccine Open
[This corrects the article DOI: 10.3389/fcimb.2022.918629.].
View article: Seroprevalence of &lt;i&gt;Leptospira&lt;/i&gt; Species and Risk Factors in Livestock and Rodents in Kondoa Town Council Dodoma, Tanzania
Seroprevalence of <i>Leptospira</i> Species and Risk Factors in Livestock and Rodents in Kondoa Town Council Dodoma, Tanzania Open
Leptospirosis remains a globally re-emerging zoonotic disease, undermining livestock productivity and posing public health risks. A cross-sectional study was conducted to estimate the seroprevalence of<i> Leptospira</i> infecti…
View article: A Case Report of Autoimmune Haemolytic Anaemia in Leptospirosis, a Rare Presentation
A Case Report of Autoimmune Haemolytic Anaemia in Leptospirosis, a Rare Presentation Open
Leptospirosis is a zoonotic illness caused by pathogenic spirochetes of the genus Leptospira, which causes diverse clinical manifestations and complications. Infection is biphasic, with a bacteraemic phase and an immune-mediated phase. A s…
View article: Seroprevalence of equine leptospirosis in Poland (2019–2023)
Seroprevalence of equine leptospirosis in Poland (2019–2023) Open
Background Leptospirosis in horses is associated with various clinical signs, potentially leading to fatal outcomes. Additionally, the disease may pose a zoonotic risk to individuals involved in handling infected animals. Implementing a se…
View article: Bovine Leptospirosis: Serology, Isolation, and Risk Factors in Dairy Farms of La Laguna, Mexico
Bovine Leptospirosis: Serology, Isolation, and Risk Factors in Dairy Farms of La Laguna, Mexico Open
Leptospirosis is a globally significant zoonosis affecting animal health, productivity, and the environment. While typically associated with tropical climates, its persistence in semi-arid regions such as La Laguna, Mexico—characterized by…
View article: Pathogenic <i>Leptospira</i> species identified in dogs and cats during neutering in Thailand
Pathogenic <i>Leptospira</i> species identified in dogs and cats during neutering in Thailand Open
Pathogenic species of Genus Leptospira cause an underdiagnosed zoonosis in humans and animals called leptospirosis. Animal reservoirs getting infections without signs can carry and shed the active spirochete into the environment through th…