Photorefractive keratectomy
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Recurrent corneal erosion: a comprehensive review Open
Newly introduced therapies for RCE enable therapy to be individualized and lower the recurrence rate.
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Chronic dry eye in photorefractive keratectomy and laser in situ keratomileusis: Manifestations, incidence, and predictive factors Open
The authors have no financial interest in any product, drug, instrument, or equipment discussed in this manuscript.
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Ectasia After Corneal Refractive Surgery: A Systematic Review Open
Post-refractive ectasia occurs at lower rates in eyes undergoing PRK than LASIK. Although SMILE appears to have the lowest rate of ectasia, the number of cases already reported since its recent approval suggests that post-SMILE ectasia may…
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Risk profiles of ectasia after keratorefractive surgery Open
Ectasia after refractive surgery is a relatively rare complication which can lead to sight-threatening complications if not detected and treated in time. It is important to continue our quest to improve our methods of identifying absolute …
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Customized Finite Element Modelling of the Human Cornea Open
Patient-specific numerical models of the cornea can provide accurate quantitative information on the refractive properties of the cornea under different levels of IOP and describe the change of the stress state of the cornea due to refract…
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Changes in biomechanically corrected intraocular pressure and dynamic corneal response parameters before and after transepithelial photorefractive keratectomy and femtosecond laser–assisted laser in situ keratomileusis Open
The dynamic Scheimpflug analyzer showed stable biomechanically corrected IOP measurement before and after surgery. The changes in dynamic corneal response parameters were smaller with transepithelial PRK than with femtosecond-assisted LASI…
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Clinical Outcomes of SMILE With a Triple Centration Technique and Corneal Wavefront-Guided Transepithelial PRK in High Astigmatism Open
PURPOSE: To comparatively investigate the clinical outcomes, vector parameters, and corneal aberrations of small incision lenticule extraction (SMILE) with a triple centration technique and corneal wavefront-guided transepithelial photoref…
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Pathophysiology of Corneal Scarring in Persistent Epithelial Defects After PRK and Other Corneal Injuries Open
PURPOSE: To analyze corneal persistent epithelial defects that occurred at 3 to 4 weeks after −4.50 diopter (D) photorefractive keratectomy (PRK) in rabbits and apply this pathophysiology to the treatment of persistent epithelial defects t…
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Regeneration of Defective Epithelial Basement Membrane and Restoration of Corneal Transparency After Photorefractive Keratectomy Open
PURPOSE: To study regeneration of the normal ultrastructure of the epithelial basement membrane (EBM) in rabbit corneas that had −9.00 D photorefractive keratectomy (PRK) and developed late haze (fibrosis) with restoration of transparency …
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Refractive lenticule extraction small incision lenticule extraction: A new refractive surgery paradigm Open
Small incision lenticule extraction (SMILE), a variant of refractive lenticule extraction technology is becoming increasingly popular, as a flapless and minimally invasive form of laser vision correction (LVC) for the treatment of myopia a…
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Refractive surgery and dry eye - An update Open
Dry eye disease is the most common complication and a frequent cause of patient dissatisfaction after corneal laser refractive surgery, which includes laser-assisted in situ keratomileusis (LASIK), small-incision lenticule extraction (SMIL…
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Transepithelial photorefractive keratectomy for low to moderate myopia in comparison with conventional photorefractive keratectomy Open
Transepithelial PRK seems to be superior to conventional PRK for treatment of low to moderate myopia in terms of postoperative pain, epithelial healing time, visual recovery and safety and efficacy indexes.
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Corneal re-innervation following refractive surgery treatments Open
Laser refractive surgery is one of the most performed surgical procedures in the world. Although regarded safe and efficient, it has side effects. All of the laser based refractive surgical procedures invoke corneal nerve injury to some de…
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Efficacy of Different Procedures of Intra-Corneal Ring Segment Implantation in Keratoconus: a Systematic Review and Meta-Analysis Open
To propose an overview of postoperative parameters on each ICRS procedure on keratoconus.
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Biomechanical Effects of tPRK, FS-LASIK, and SMILE on the Cornea Open
Purpose: The objective of this study is to evaluate the in vivo corneal biomechanical response to three laser refractive surgeries. Methods: Two hundred and twenty-seven patients who submitted to transepithelial photorefractive keratectomy…
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Corneal Epithelial Remodeling and Its Effect on Corneal Asphericity after Transepithelial Photorefractive Keratectomy for Myopia Open
Purpose. To evaluate the changes in epithelial thickness profile following transepithelial photorefractive keratectomy (T-PRK) for myopia and to investigate the effect of epithelial remodeling on corneal asphericity. Methods. Forty-four pa…
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A Critical Overview of the Biological Effects of Mitomycin C Application on the Cornea Following Refractive Surgery Open
During the last 2 decades, modifying the shape of the cornea by means of laser photoablation has emerged as a successful and popular treatment option for refractive errors. Corneal surface ablation techniques such as photorefractive kerate…
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Corneal neuromediator profiles following laser refractive surgery Open
Laser refractive surgery is one of the most commonly performed procedures worldwide. In laser refractive surgery, Femtosecond Laser in Situ Keratomileusis and Refractive Lenticule Extraction have emerged as promising alternatives to microk…
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Mechanisms of Optical Regression Following Corneal Laser Refractive Surgery: Epithelial and Stromal Responses. Open
Laser vision correction is a safe and effective method of reducing spectacle dependence. Photorefractive Keratectomy (PRK), Laser In Situ Keratomileusis (LASIK), and Small-Incision Lenticule Extraction (SMILE) can accurately correct myopia…
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Main Complications of Photorefractive Keratectomy and their Management Open
Photorefractive keratectomy (PRK) was the first surface ablation procedure introduced for the treatment of refractive errors and has been proven to be effective and safe. In some cases, however, the patient may not be totally satisfied wit…
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Effect of accelerated corneal crosslinking combined with transepithelial photorefractive keratectomy on dynamic corneal response parameters and biomechanically corrected intraocular pressure measured with a dynamic Scheimpflug analyzer in healthy myopic patients Open
Results indicate that prophylactic CXL combined with transepithelial PRK has a role in reducing the change in corneal biomechanical properties. The dynamic Scheimpflug analyzer showed stable biomechanically corrected IOP measurements preop…
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Adipose Derived Stem Cells for Corneal Wound Healing after Laser Induced Corneal Lesions in Mice Open
The aim of our study was to assess the clinical effectiveness of topical adipose derived stem cell (ADSC) treatment in laser induced corneal wounds in mice by comparing epithelial repair, inflammation, and histological analysis between tre…
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Laser-assisted subepithelial keratectomy (LASEK) versus photorefractive keratectomy (PRK) for correction of myopia Open
Uncertainty surrounds differences in efficacy, accuracy, safety, and adverse effects between LASEK and PRK for eyes with low to moderate myopia. Future trials comparing LASEK versus PRK should follow reporting standards and follow correct …
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Early clinical outcomes and comparison between trans-PRK and PRK, regarding refractive outcome, wound healing, pain intensity and visual recovery time in a real‐world setup Open
Purpose To compare early clinical outcomes of single-step transepithelial photorefractive keratectomy (tPRK) and photorefractive keratectomy (PRK) regarding refractive outcome, visual acuity, wound healing, pain intensity and visual recove…
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Binocular vision alterations after refractive and cataract surgery: a review Open
To review binocular and accommodative disorders documented after corneal or intraocular refractive surgery, in normal healthy prepresbyopic patients. A bibliographic revision was performed; it included works published before 1st July 2017 …
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Predictive factors for efficacy and safety in refractive surgery for myopia Open
Efficacy in refractive surgery for myopia is correlated with younger age, male gender and low myopia. Safety is correlated with younger age, low myopia and increases over the years. Multivariate analysis found no differences between PRK an…
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Corneal Molecular and Cellular Biology for the Refractive Surgeon: The Critical Role of the Epithelial Basement Membrane Open
PURPOSE: To provide an overview of the recent advances concerning the corneal molecular and cellular biology processes involved in the wound healing response after excimer laser surface ablation and LASIK surgery. METHODS: Literature revie…
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Standard cross‐linking versus photorefractive keratectomy combined with accelerated cross‐linking for keratoconus management: a comparative study Open
Purpose To compare the safety and efficacy of standard 30 min epithelium‐off cross‐linking ( CXL ) versus photorefractive keratectomy ( PRK ) combined with accelerated epithelium‐off cross‐linking ( AXL ) for the treatment of progressive k…
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Combined corneal CXL and photorefractive keratectomy for treatment of keratoconus: a review Open
Keratoconus and iatrogenic keratectasia are the corneal ectatic disorders occurring due to biomechanical weakening of the cornea resulting in distorted images, myopia, and irregular astigmatism. Corneal collagen cross-linking (CXL) is perf…
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Epithelium-on photorefractive intrastromal cross-linking (PiXL) for reduction of low myopia Open
This paper serves to introduce and report the early clinical results of epithelium-on PiXL, a novel application of cornea cross-linking, in reducing low myopia in Asian eyes, which are under-represented in studies of similar design.