Crackles ≈ Crackles
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The Agreement between Auscultation and Lung Ultrasound in Hemodialysis Patients: The LUST Study Open
Background and objectives Accumulation of fluid in the lung is the most concerning sequela of volume expansion in patients with ESRD. Lung auscultation is recommended to detect and monitor pulmonary congestion, but its reliability in ESRD …
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Automated Lung Sound Classification Using a Hybrid CNN-LSTM Network and Focal Loss Function Open
Respiratory diseases constitute one of the leading causes of death worldwide and directly affect the patient’s quality of life. Early diagnosis and patient monitoring, which conventionally include lung auscultation, are essential for the e…
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Life-threatening bronchiolitis related to electronic cigarette use in a Canadian youth Open
This case of severe acute bronchiolitis, causing near-fatal hypercapnic respiratory failure and chronic airflow obstruction in a previously healthy Canadian youth, may represent vaping-associated bronchiolitis obliterans. This novel patter…
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Rapid and severe Covid‐19 pneumonia with severe acute chest syndrome in a sickle cell patient successfully treated with tocilizumab Open
On 25 March 2020 presence of multifocal vaso-occlusive crises (VOC) for the past 24 hours was determined in a 45-year-old male patient with homozygous sickle cell disease (SCD) by the "DREPADOM" network. This was a phone consultation clini…
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Routine application of lung ultrasonography in the neonatal intensive care unit Open
The aim of this study was to study the features of lung ultrasonography (LUS) in lung disease and to evaluate the usefulness of LUS in the neonatal intensive care unit (NICU).All of 3405 neonates included in this study underwent an LUS exa…
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Practical implementation of artificial intelligence algorithms in pulmonary auscultation examination Open
Lung auscultation is an important part of a physical examination. However, its biggest drawback is its subjectivity. The results depend on the experience and ability of the doctor to perceive and distinguish pathologies in sounds heard via…
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Early Diagnosis of Pneumonia in Severe Stroke: Clinical Features and the Diagnostic Role of C-Reactive Protein Open
Patients with severe stroke frequently do not manifest key diagnostic features of pneumonia such as pyrexia, cough and purulent sputum early in their illness. The most common signs in this group are new-onset crackles, tachypnoea and hypox…
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Automatic Classification of Adventitious Respiratory Sounds: A (Un)Solved Problem? Open
(1) Background: Patients with respiratory conditions typically exhibit adventitious respiratory sounds (ARS), such as wheezes and crackles. ARS events have variable duration. In this work we studied the influence of event duration on autom…
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Wheezes, crackles and rhonchi: simplifying description of lung sounds increases the agreement on their classification: a study of 12 physicians' classification of lung sounds from video recordings Open
Background The European Respiratory Society (ERS) lung sounds repository contains 20 audiovisual recordings of children and adults. The present study aimed at determining the interobserver variation in the classification of sounds into det…
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“Velcro-type” crackles predict specific radiologic features of fibrotic interstitial lung disease Open
"Velcro-type" crackles predict the presence of FILD and directly correlate with the extent of distinct radiologic features of pulmonary fibrosis. Such evidence provides grounds for further investigation of lung sounds as an early identific…
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Chest Radiograph Findings in Childhood Pneumonia Cases From the Multisite PERCH Study Open
Clinically diagnosed pneumonia cases with abnormal CXRs were more likely to have signs typically associated with pneumonia. However, CXR-normal cases were common, and clinical signs considered indicative of pneumonia were present in substa…
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Diagnostic accuracy of a velcro sound detector (VECTOR) for interstitial lung disease in rheumatoid arthritis patients: the InSPIRAtE validation study (INterStitial pneumonia in rheumatoid ArThritis with an electronic device) Open
VECTOR may represent the first validated tool for the screening of RA patients who are suspected for ILD and who should be directed to HRCT for the diagnosis. Moreover, early identification of RA-ILD could contribute to the design of prosp…
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The accuracy of lung auscultation in the practice of physicians and medical students Open
These results confirm that ambiguous identification and interpretation of sounds in auscultation is a generic issue which should not be neglected as it can potentially lead to inaccurate diagnosis and mistreatment. Our results lend further…
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Reliability of Examination Findings in Suspected Community-Acquired Pneumonia Open
BACKGROUND: The authors of national guidelines emphasize the use of history and examination findings to diagnose community-acquired pneumonia (CAP) in outpatient children. Little is known about the interrater reliability of the physical ex…
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Socioeconomic Status, Smoke Exposure, and Health Outcomes in Young Children With Cystic Fibrosis Open
BACKGROUND: Lower socioeconomic status (SES) and environmental tobacco smoke (ETS) exposure are both associated with poorer disease outcomes in cystic fibrosis (CF), and children with low SES are disproportionately exposed to ETS. We analy…
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Predictors of pneumonia in lower respiratory tract infections: 3C prospective cough complication cohort study Open
The aim was to aid diagnosis of pneumonia in those presenting with lower respiratory tract symptoms in routine primary care. A cohort of 28 883 adult patients with acute cough attributed to lower respiratory tract infections (LRTIs) was re…
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Auscultation of Velcro Crackles is Associated With Usual Interstitial Pneumonia Open
Auscultation of Velcro crackles has been proposed as a key finding in physical lung examination in patients with interstitial lung diseases (ILDs), especially in idiopathic pulmonary fibrosis (IPF). However, no studies have been carried ou…
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Antibiotics for persistent cough or wheeze following acute bronchiolitis in children Open
Current evidence is insufficient to inform whether antibiotics should be used to treat or prevent persistent respiratory symptoms in the post-acute bronchiolitis phase. Future RCTs are needed to evaluate the efficacy of antibiotics for red…
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Nivolumab-induced organizing pneumonia in a melanoma patient Open
We report the case of a 70-year-old woman with vaginal melanoma and multiple metastases in the lung. After the third dose of nivolumab, decreased room-air resting arterial oxygen saturation with bilateral basal fine crackles on auscultatio…
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Therapeutic management of patients with rheumatoid arthritis and associated interstitial lung disease: case report and literature review Open
Rheumatoid arthritis (RA) is an inflammatory autoimmune disease that can present different extrarticular manifestations involving heart, lungs and kidneys. In recent years there has been a growing awareness of the central role played by th…
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Community-Acquired Pneumonia Caused by Mycoplasma pneumoniae: How Physical and Radiological Examination Contribute to Successful Diagnosis Open
Mycoplasma pneumoniae is one of the most common causes of community-acquired pneumonia (CAP), particularly in young adults. Vital signs are usually normal except for temperature. On physical examination, general appearance is normal compar…
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Multimedia Respiratory Database (RespiratoryDatabase@TR): Auscultation Sounds and Chest X-rays Open
Auscultation is a method for diagnosis of especially internal medicine diseases such as cardiac, pulmonary and cardio-pulmonary by listening the internal sounds from the body parts. It is the simplest and the most common physical examinati…
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Exercise-Induced Oxygen Desaturation during the 6-Minute Walk Test Open
The 6-minute walk test (6MWT) is not intended to document oxygen (O2) desaturation during exertion but is often used for this purpose. Because of this, it only has modest reproducibility in determining the need for ambulatory O2 therapy in…
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Detection of pathological mechano-acoustic signatures using precision accelerometer contact microphones in patients with pulmonary disorders Open
Monitoring pathological mechano-acoustic signals emanating from the lungs is critical for timely and cost-effective healthcare delivery. Adventitious lung sounds including crackles, wheezes, rhonchi, bronchial breath sounds, stridor or ple…
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Respiratory Diseases Diagnosis Using Audio Analysis and Artificial Intelligence: A Systematic Review Open
Respiratory diseases represent a significant global burden, necessitating efficient diagnostic methods for timely intervention. Digital biomarkers based on audio, acoustics, and sound from the upper and lower respiratory system, as well as…
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A Wearable Multimodal Sensing System for Tracking Changes in Pulmonary Fluid Status, Lung Sounds, and Respiratory Markers Open
Heart failure (HF) exacerbations, characterized by pulmonary congestion and breathlessness, require frequent hospitalizations, often resulting in poor outcomes. Current methods for tracking lung fluid and respiratory distress are unable to…
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A machine learning approach to the development and prospective evaluation of a pediatric lung sound classification model Open
Auscultation, a cost-effective and non-invasive part of physical examination, is essential to diagnose pediatric respiratory disorders. Electronic stethoscopes allow transmission, storage, and analysis of lung sounds. We aimed to develop a…
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Real-World Verification of Artificial Intelligence Algorithm-Assisted Auscultation of Breath Sounds in Children Open
Objective: Lung auscultation plays an important role in the diagnosis of pulmonary diseases in children. The objective of this study was to evaluate the use of an artificial intelligence (AI) algorithm for the detection of breath sounds in…
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Clinical characteristics and outcomes of hypersensitivity pneumonitis Open
The clinical features and outcomes of the CHP patients differ from those of the AHP patients. ADSUC is a simple and feasible clinical model for CHP. Unidentified exposure is an independent risk factor for the progression of AHP to CHP. Uni…
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Cochleogram-based adventitious sounds classification using convolutional neural networks Open
The World Health Organization (WHO) establishes as a top priority the early detection of respiratory diseases. This detection could be performed by means of recognizing the presence of acoustic bio-markers (adventitious sounds) from auscul…