Waldenstrom macroglobulinemia

Defining the proteome of bone marrow plasma in multiple myeloma and monoclonal gammopathy of undetermined significance Open

Joel-Sean Hsu, Udit Yadav, Kishore Garapati, Kiran K Mangalaparthi, Yogesh Chawla , et al. · 2025

Clonal identification and homology differentiate primary central nervous system lymphoma from non-central nervous system lymphoplasmacytic lymphoma: a case report Open

Yuko Tanaka, Nahoko Furuya, Seiichi Okabe, Seiichiro Yosizawa, Seiichiro Katagiri , et al. · 2025

It was revealed that the lymphoma cells of both lymphoplasmacytic lymphoma/Waldenström macroglobulinemia and primary central nervous system lymphoma derived from a common cell possessing MYD88. The utility of adding chemotherapy for low-gr…

Transformation and survival in patients with Waldenström macroglobulinemia: a population-based study Open

Yu Du, Xiaona Chang, Xiangxiang Li, Shugang Xing · 2025

Background Waldenström’s macroglobulinemia (WM) is a rare hematologic neoplasm characterized by an indolent clinical course. However, a significant proportion of patients undergo histological transformation to aggressive diffuse large B-ce…

IMG-17. Expanding the radiological spectrum of Bing-Neel syndrome: a case report Open

Nynoshka Bassatt Cabrera, Siara Clos, Jenny Meyer · 2025

Bing-Neel Syndrome (BNS) is a rare neurological complication of lymphoplasmacytic lymphoma (LPL), also known as Waldenström macroglobulinemia (WM). It has been reported in approximately 0.8% of patients with LPL1. It is more common in olde…

231 IgM Multiple Myeloma with Plasma cell leukemia, a rare hematological entity Open

Ines Butka, Jalil Nasibli, Ashish Bains, Melissa Ulas · 2025

Introduction/Objective IgM multiple myeloma (MM) is a rare subtype, accounting for approximately 0.5% of all myeloma cases. Plasma cell leukemia (PCL) is an aggressive plasma cell dyscrasia defined as an elevated presence of plasma cells i…

Rare coagulopathy in the setting of multiple myeloma and Waldenström’s macroglobulinemia — a case report Open

Agata Ogłoza, Andrzej Mital, Agata Ogłoza, Andrzej Mital · 2025

Long-term follow-up of venetoclax monotherapy in previously treated patients with Waldenström macroglobulinemia. Open

Jorge J. Castillo, Alberto Güijosa, John N. Allan, Tanya Siddiqi, Ranjana H. Advani , et al. · 2025

Venetoclax is highly active in previously treated Waldenström macroglobulinemia (WM). However, data on the long-term durability and retreatment with venetoclax remain limited. Herein, we present an update of a prospective clinical trial of…

Prevalence and Clinical Correlates of MYD88 L265P Mutation in Sudanese Patients with Chronic Lymphocytic Leukemia Open

Dafaalla Ahmed, Husameldin Abdelrahim, Ahmed, Nadia Madani Mohamed · 2025

Background: The MYD88 L265P mutation is well established in lymphoplasmacytic lymphoma and Waldenström macroglobulinemia but is uncommon in chronic lymphocytic leukemia (CLL). Data on its prevalence and clinical s…

Aggressive B cell lymphomas retain ATR-dependent determinants of T cell exclusion from the germinal center dark zone Open

Cancila, Valeria, Bertolazzi, Giorgio, Chan, Allison S.Y., Medico, Giovanni, Bastianello, Giulia , et al. · 2025

The germinal center (GC) dark zone (DZ) and light zone represent distinct anatomical regions in lymphoid tissue where B cell proliferation, immunoglobulin diversification, and selection are coordinated. Diffuse large B cell lymphomas (DLBC…

Epidemiology, Real-World Treatment, and Economic Burden of Waldenström Macroglobulinemia: A Comprehensive Analysis Based on Anonymized Claims Data Between 2010 and 2022 Open

Christian Buske, Michael Herold, Nasim Bahar, Keri Yang, Boxiong Tang , et al. · 2025

Distinct molecular subtypes in Waldenström macroglobulinemia Open

Zachary R. Hunter, Steven P. Treon · 2025

MACROGLOBULINEMIA DE WALDENSTROM: DIAGNÓSTICO DIFERENCIAL E NOVAS ABORDAGENS TERAPÊUTICAS. Open

Jorge Rosemberg Bezerra Ramos, Letícia dos Anjos Leite, Bruna Martins Gomes, José Nilton de Araújo Minervino, Vivianne Lúcia Bormann de Souza , et al. · 2025

A Macroglobulinemia de Waldenström (MW) é uma neoplasia linfoproliferativa rara, marcada pela produção de imunoglobulina M (IgM) monoclonal e infiltração medular por células linfoplasmocíticas. Seu espectro clínico inclui manifestações com…

Monoclonal gammopathy defines distinct clinical subsets in Chronic Lymphocytic Leukemia across therapeutic eras Open

Yuting Yan, BAO DING YUAN, Tonglu Qiu, Guoqiang Liu, Weihao Chen , et al. · 2025

Monoclonal gammopathy (MG) in chronic lymphocytic leukemia (CLL) portends heterogeneous outcomes, yet its molecular drivers and therapeutic implications remain undefined. In this retrospective analysis of 2,075 CLL patients (1999-2024), MG…

A Case of Waldenstrom’s Macroglobulinemia Presenting as Worsening Neuropathy Open

Meher Binte Ali, Zunera Huda, Marc Hendricks, Kathryn Kline, Danish Jilani · 2025

P128 | Beyond thresholds: hyperviscosity syndrome in Waldenström’s macroglobulinemia - A Case report Open

2025

Premises: Hyperviscosity syndrome (HVS) is marked by abnormal blood flow resulting from disorders in blood cell and plasma components. Most of the serum component abnormalities are caused by plasma cell dyscrasias, among these Waldenstrom’…

A Rare Case of Waldenström Macroglobulinemia Presenting as Bilateral Bloody Pleural Effusion and Pancytopenia Open

Yue Qing Chen, Hua Wang, Qiong Feng · 2025

BACKGROUND Waldenström macroglobulinemia (WM) is an uncommon, indolent mature B-cell lymphoma with various clinical manifestations. Bilateral bloody pleural effusion is rare, while chylothorax is even more infrequent. Furthermore, pancytop…

Cardiac light chain amyloidosis secondary to Waldenström's macroglobulinemia: A case report and review Open

Fang Du, Ai Guilan, Lingyun Zhou, Danbo Liu, Jiao Chen , et al. · 2025

Cardiac light chain amyloidosis (AL) secondary to Waldenström's macroglobulinemia (WM) presents a complex challenge in medical practice due to its rarity and diagnostic difficulty. A 67-year-old male presented with symptoms of heart failur…

Acute kidney injury after pulsed field ablation in a patient with Waldenström’s macroglobulinemia: A case report Open

Masanaru Sawada, Koichi Nagashima, Ryuta Watanabe, Yuji Saito, Yuji Wakamatsu , et al. · 2025

Genetic background of Richter transformation of atypical chronic lymphocytic leukemia to diffuse large B-cell lymphoma - a case study Open

Sandra Przybysz, Anna Łojko‐Dankowska, Magdalena Rakoczy, Małgorzata Marcinkowska, Michał Zeńczak , et al. · 2025

Atypical chronic lymphocytic leukemia (aCLL) is an indolent lymphoproliferative neoplasm derived from CD19-positive and CD5 or CD23-negative B cells. This paper presents the results of whole genome sequencing (WGS) of lymphoma cells collec…

An Extremely Rare Cause of Protein-Losing Enteropathy: Waldenström Macroglobulinemia Open

Omar N. Saab, Marwah Algodi, Hasan Al‐Obaidi, Alhareth Al-Sagban, Sebouh Setrakian , et al. · 2025

Protein-losing enteropathy (PLE) results in the abnormal loss of proteins through the gastrointestinal tract, leading to malabsorption and hypoalbuminemia. A rare etiology of PLE is Waldenström macroglobulinemia (WM), a hematological malig…

Knowledge, Attitudes, and Practices Towards Waldenström’s Macroglobulinemia Among Patients and Their Family Members Open

Yang Yang, Xiaolin Gu, Enfan Zhang, Jingsong He, Zhen Cai · 2025

WM patients and their family members demonstrated moderate levels of knowledge, attitudes, and practices toward WM. To enhance clinical outcomes, interventions should focus on improving attitudes, given their direct and negative impact on …

Obinutuzumab induction and maintenance in patients with Waldenström macroglobulinaemia: an open-label, single-arm phase 2 study Open

Tomasz Wróbel, Elżbieta Kalicińska, Jan Maciej Zaucha, Marta Morawska, Krzysztof Giannopoulos , et al. · 2025

Current risk stratification and staging of multiple myeloma and related clonal plasma cell disorders Open

Saurabh Zanwar, S. Vincent Rajkumar · 2025

CONTRIBUTO DA EXPRESSÃO DE CD13 NO DIAGNÓSTICO DE MACROGLOBULINEMIA DE WALDENSTRÖM - LINFOMA LINFOPLASMOCÍTICO: UM CASO CLÍNICO Open

F.M. Gonçalves, Ana Marta Pinto, PATRÍCIA PILAR GOMES OLIVEIRA MAIA, Bruno Fernandes, Marta Martins · 2025

Laboratory Characteristics of Lymphoplasmacytic Lymphoma with Plasma Cells Containing “Diamond-shaped” Inclusio Open

Yu Ma, G. Zhang, Yingchun Zheng, Jihong Zhang, Shuang Wang , et al. · 2025

Ibrutinib plus rituximab vs ibrutinib monotherapy in patients with Waldenström macroglobulinemia: a pooled analysis Open

Alberto Güijosa, Andres Ramirez‐Gamero, Shayna Sarosiek, Andrew R. Branagan, Gottfried von Keudell , et al. · 2025

Ibrutinib (I) and ibrutinib plus rituximab (I+R) are highly efficacious in treating Waldenström macroglobulinemia (WM). However, the benefit of adding rituximab remains unclear, and a prospective trial to compare these two regimens has not…

The therapeutic perspective of relapsed/refractory Waldenström Macroglobulinemia: what comes next? Open

Nicolò Danesin, Giovanni Leone, Mattia D’Antiga, Marco Carraro, Greta Scapinello , et al. · 2025

Waldenström Macroglobulinemia (WM) is a rare, indolent B-cell lymphoma that primarily affects elderly individuals. Although frontline chemoimmunotherapy and Bruton’s tyrosine kinase inhibitors (BTKi) can provide durable responses, most pat…

Mesenteric Mass Causing Bowel Obstruction in Waldenström Macroglobulinemia Open

Eduarda Magalhães, P Sousa, José Pedro Pinto, Fernando Manso, Ana Cristina Ribeiro · 2025

Lymphadenopathy is an independent prognostic factor for patients with Waldenström macroglobulinaemia Open

Ioannis Ntanasis‐Stathopoulos, Charalampos Filippatos, Despina Fotiou, Vassiliki Labropoulou, Nikolaos Giannakoulas , et al. · 2025

Waldenström macroglobulinemia Open

Henry Knipe · 2025