Seeding ≈ Seeding
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SPOTlight: seeded NMF regression to deconvolute spatial transcriptomics spots with single-cell transcriptomes Open
Spatially resolved gene expression profiles are key to understand tissue organization and function. However, spatial transcriptomics (ST) profiling techniques lack single-cell resolution and require a combination with single-cell RNA seque…
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Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose) Open
Intrinsically disordered proteins can phase separate from the soluble intracellular space, and tend to aggregate under pathological conditions. The physiological functions and molecular triggers of liquid demixing by phase separation are n…
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A collective route to metastasis: Seeding by tumor cell clusters Open
Despite decades of study, there are still many unanswered questions about metastasis, the process by which a localized cancer becomes a systemic disease. One of these questions is the nature of the tumor cells that give rise to metastases.…
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Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy Open
Antisense oligonucleotides that reduce tau prevent neuronal loss and reverse tau deposition and seeding in a mouse model of tauopathy.
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Review of the methodologies used in the synthesis gold nanoparticles by chemical reduction Open
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Perovskite seeding growth of formamidinium-lead-iodide-based perovskites for efficient and stable solar cells Open
Formamidinium-lead-iodide (FAPbI 3 )-based perovskites with bandgap below 1.55 eV are of interest for photovoltaics in view of their close-to-ideal bandgap. Record-performance FAPbI 3 -based solar cells have relied on fabrication via the s…
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Mechanisms of mast seeding: resources, weather, cues, and selection Open
Summary Mast seeding is a widespread and widely studied phenomenon. However, the physiological mechanisms that mediate masting events and link them to weather and plant resources are still debated. Here, we explore how masting is affected …
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Kinetic model of the aggregation of alpha-synuclein provides insights into prion-like spreading Open
Significance Growing experimental evidence suggests that the pathological spreading of alpha-synuclein aggregates in Parkinson’s disease is mediated through a process of templated seeding whereby aggregates catalyze the conversion of solub…
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Oriented MFI Membranes by Gel‐Less Secondary Growth of Sub‐100 nm MFI‐Nanosheet Seed Layers Open
A zeolite membrane fabrication process combining 2D-zeolite nanosheet seeding and gel-free secondary growth is described. This process produces selective molecular sieve films that are as thin as 100 nm and exhibit record high permeances f…
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Comparative Analysis of 3D Bladder Tumor Spheroids Obtained by Forced Floating and Hanging Drop Methods for Drug Screening Open
Introduction: Cell-based assays using three-dimensional (3D) cell cultures may reflect the antitumor activity of compounds more accurately, since these models reproduce the tumor microenvironment better. Methods: Here, we report a comparat…
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Adaptive Influence Maximization in Dynamic Social Networks Open
For the purpose of propagating information and ideas through a social\nnetwork, a seeding strategy aims to find a small set of seed users that are\nable to maximize the spread of the influence, which is termed as influence\nmaximization pr…
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Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo Open
Genetic, clinical, histopathological and biomarker data strongly support Beta-amyloid (Aβ) induced spreading of Tau-pathology beyond entorhinal cortex (EC), as a crucial process in conversion from preclinical cognitively normal to Alzheime…
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Experimental Demonstration of a Soft X-Ray Self-Seeded Free-Electron Laser Open
The Linac Coherent Light Source has added a self-seeding capability to the soft x-ray range using a grating monochromator system. We report the demonstration of soft x-ray self-seeding with a measured resolving power of 2000-5000, waveleng…
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Digital Counts of Maize Plants by Unmanned Aerial Vehicles (UAVs) Open
Precision phenotyping, especially the use of image analysis, allows researchers to gain information on plant properties and plant health. Aerial image detection with unmanned aerial vehicles (UAVs) provides new opportunities in precision f…
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JWST CEERS and JADES Active Galaxies at z = 4–7 Violate the Local M <sub>•</sub>–M <sub>⋆</sub> Relation at >3σ: Implications for Low-mass Black Holes and Seeding Models Open
JWST is revolutionizing our understanding of the high- z Universe by expanding the black hole horizon, looking farther and to smaller masses, and revealing the stellar light of their hosts. By examining JWST galaxies at z = 4–7 that host H…
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Surface Modification Techniques for Endothelial Cell Seeding in PDMS Microfluidic Devices Open
Microfluidic lab-on-a-chip cell culture techniques have been gaining popularity by offering the possibility of reducing the amount of samples and reagents and greater control over cellular microenvironment. Polydimethylsiloxane (PDMS) is t…
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Flexible Nanoporous Template for the Design and Development of Reusable Anti-COVID-19 Hydrophobic Face Masks Open
Since the outbreak of the severe respiratory disease caused by the novel coronavirus (COVID-19), the use of face masks has become ubiquitous worldwide to control the rapid spread of this pandemic. As a result, the world is currently facing…
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Precipitation formation from orographic cloud seeding Open
Throughout the western United States and other semiarid mountainous regions across the globe, water supplies are fed primarily through the melting of snowpack. Growing populations place higher demands on water, while warmer winters and ear…
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BINARY: an optical freezing array for assessing temperature and time dependence of heterogeneous ice nucleation Open
A new optical freezing array for the study of heterogeneous ice nucleation in microliter-sized droplets is introduced, tested and applied to the study of immersion freezing in aqueous Snomax® suspensions. In the Bielefeld Ice Nucleation AR…
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Short Fibrils Constitute the Major Species of Seed-Competent Tau in the Brains of Mice Transgenic for Human P301S Tau Open
The interneuronal propagation of aggregated tau is believed to play an important role in the pathogenesis of human tauopathies. It requires the uptake of seed-competent tau into cells, seeding of soluble tau in recipient neurons and releas…
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Evolutionary history of metastatic breast cancer reveals minimal seeding from axillary lymph nodes Open
Metastatic breast cancers are still incurable. Characterizing the evolutionary landscape of these cancers, including the role of metastatic axillary lymph nodes (ALNs) in seeding distant organ metastasis, can provide a rational basis for e…
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Direct Seeding in Reforestation – A Field Performance Review Open
Direct seeding has been considered a forest restoration option for centuries. Over the past half century, the use of this practice has declined in developed countries as forest regeneration programs have advanced with the production of qua…
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Ice nucleation efficiency of AgI: review and new insights Open
AgI is one of the best-investigated ice-nucleating substances. It has relevance for the atmosphere since it is used for glaciogenic cloud seeding. Theoretical and experimental studies over the last 60 years provide a complex picture of sil…
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Soluble tau aggregates, not large fibrils, are the toxic species that display seeding and cross‐seeding behavior Open
Several studies have proposed that fibrillary aggregates of tau and other amyloidogenic proteins are neurotoxic and result in numerous neurodegenerative diseases. However, these studies usually involve sonication or extrusion through needl…
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Agricultural practices altered soybean seed protein, oil, fatty acids, sugars, and minerals in the Midsouth USA Open
Information on the effects of management practices on soybean seed composition is scarce. Therefore, the objective of this research was to investigate the effects of planting date (PD) and seeding rate (SR) on seed composition (protein, oi…
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Chiral Seeded Growth of Gold Nanorods Into Fourfold Twisted Nanoparticles with Plasmonic Optical Activity Open
A robust and reproducible methodology to prepare stable inorganic nanoparticles with chiral morphology may hold the key to the practical utilization of these materials. An optimized chiral growth method to prepare fourfold twisted gold nan…
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Pre-sowing Seed Treatments in Direct-seeded Early Rice: Consequences for Emergence, Seedling Growth and Associated Metabolic Events under Chilling Stress Open
Double direct-seeding for double rice cropping is a simplified, labor saving and efficient cropping system to improve multiple-crop index and total rice production in central China. However, poor crop establishment of direct-seeded early r…
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A Universal Seeding Strategy to Synthesize Single Atom Catalysts on 2D Materials for Electrocatalytic Applications Open
Single‐atom catalysts (SACs) are attracting significant attention due to their exceptional catalytic performance and stability. However, the controllable, scalable, and efficient synthesis of SACs remains a significant challenge. Herein, a…
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Power exhaust by SOL and pedestal radiation at ASDEX Upgrade and JET Open
Future fusion reactors require a safe, steady state divertor operation. A possible solution for the power exhaust challenge is the detached divertor operation in scenarios with high radiated power fractions. The radiation can be increased …
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Agronomic Practices for Reducing Wheat Yield Gaps: A Quantitative Appraisal of Progressive Producers Open
There is limited information on agronomic practices affecting wheat ( Triticum aestivum L.) yield in intensively managed dryland systems despite the opportunity to narrow the existing yield gap ( Y G ). We used a unique database of 100 int…