Point spread function ≈ Point spread function
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Nanometer resolution imaging and tracking of fluorescent molecules with minimal photon fluxes Open
Superresolution imaging in sharper focus An optical microscope cannot distinguish objects separated by less than half the wavelength of light. Superresolution techniques have broken this “diffraction limit” and provided exciting new insigh…
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Practical Weak-lensing Shear Measurement with Metacalibration Open
Metacalibration is a recently introduced method to accurately measure weak gravitational lensing shear using only the available imaging data, without need for prior information about galaxy properties or calibration from simulations. The m…
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Efficient positional misalignment correction method for Fourier ptychographic microscopy Open
Fourier ptychographic microscopy (FPM) is a newly developed super-resolution technique, which employs angularly varying illuminations and a phase retrieval algorithm to surpass the diffraction limit of a low numerical aperture (NA) objecti…
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The DES Science Verification weak lensing shear catalogues Open
We present weak lensing shear catalogs for 139 square degrees of data taken during the Science Verification (SV) time for the new Dark Energy Camera (DECam) being used for the Dark Energy Survey (DES). We describe our object selection, poi…
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Far-Field Superresolution of Thermal Electromagnetic Sources at the Quantum Limit Open
We obtain the ultimate quantum limit for estimating the transverse separation of two thermal point sources using a given imaging system with limited spatial bandwidth. We show via the quantum Cramér-Rao bound that, contrary to the Rayleigh…
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Digital confocal microscopy through a multimode fiber Open
Acquiring high-contrast optical images deep inside biological tissues is still a challenging problem. Confocal microscopy is an important tool for biomedical imaging since it improves image quality by rejecting background signals. However,…
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Compact snapshot hyperspectral imaging with diffracted rotation Open
Traditional snapshot hyperspectral imaging systems include various optical elements: a dispersive optical element (prism), a coded aperture, several relay lenses, and an imaging lens, resulting in an impractically large form factor. We see…
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Coded aperture correlation holography–a new type of incoherent digital holograms Open
We propose and demonstrate a new concept of incoherent digital holography termed coded aperture correlation holography (COACH). In COACH, the hologram of an object is formed by the interference of light diffracted from the object, with lig…
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GREAT3 results – I. Systematic errors in shear estimation and the impact of real galaxy morphology Open
We present first results from the third GRavitational lEnsing Accuracy Testing (GREAT3) challenge, the third in a sequence of challenges for testing methods of inferring weak gravitational lensing shear distortions from simulated galaxy im…
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The wide-field multiband imaging and slitless spectroscopy survey to be carried out by the Survey Space Telescope of China Manned Space Program Open
The 2 m-aperture Survey Space Telescope (also known as the China Space Station Telescope, CSST) is a major science project of China Manned Space Program. It is expected to start science operations around 2024 and has a nominal mission life…
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Super-resolution spinning-disk confocal microscopy using optical photon reassignment Open
Spinning-disk confocal microscopy is a proven technology for investigating 3D structures of biological specimens. Here we report a super-resolution method based on spinning-disk confocal microscopy that optically improves lateral resolutio…
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Solving Fourier ptychographic imaging problems via neural network modeling and TensorFlow Open
Fourier ptychography is a recently developed imaging approach for large field-of-view and high-resolution microscopy. Here we model the Fourier ptychographic forward imaging process using a convolutional neural network (CNN) and recover th…
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Non-linear adaptive three-dimensional imaging with interferenceless coded aperture correlation holography (I-COACH) Open
Interferenceless coded aperture correlation holography (I-COACH) is an incoherent digital holography technique for imaging 3D objects without two-wave interference. In I-COACH, the object beam is modulated by a pseudorandom coded phase mas…
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3D printed diffractive terahertz lenses Open
A 3D printer was used to realize custom-made diffractive THz lenses. After testing several materials, phase binary lenses with periodic and aperiodic radial profiles were designed and constructed in polyamide material to work at 0.625 THz.…
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Clinically Relevant Optical Properties of Bifocal, Trifocal, and Extended Depth of Focus Intraocular Lenses Open
PURPOSE: To experimentally compare the optical performance of three types of hydrophobic intraocular lenses (IOLs): extended depth of focus, bifocal, and trifocal. METHODS: The tested IOLs were: TECNIS ZMB00 (bifocal; Abbott Medical Optics…
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Improving and Assessing Planet Sensitivity of the GPI Exoplanet Survey with a Forward Model Matched Filter Open
We present a new matched-filter algorithm for direct detection of point sources in the immediate vicinity of bright stars. The stellar point-spread function (PSF) is first subtracted using a Karhunen-Loéve image processing (KLIP) algorithm…
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GalPaK<sup>3D</sup>: A BAYESIAN PARAMETRIC TOOL FOR EXTRACTING MORPHOKINEMATICS OF GALAXIES FROM 3D DATA Open
We present a method to constrain galaxy parameters directly from three-dimensional data cubes. The algorithm compares directly the data with a parametric model mapped in coordinates. It uses the spectral line-spread function and the spatia…
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Multicolor localization microscopy and point-spread-function engineering by deep learning Open
Deep learning has become an extremely effective tool for image classification and image restoration problems. Here, we apply deep learning to microscopy and demonstrate how neural networks can exploit the chromatic dependence of the point-…
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Extend the field of view of selective plan illumination microscopy by tiling the excitation light sheet Open
Selective Plane Illumination Microscopy (SPIM) is attractive for its ability to acquire 3D images with high 3D spatial resolution, good optical sectioning capability and high imaging speed. However, tradeoffs have to be made when a large f…
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Modern description of Rayleigh's criterion Open
Rayleigh's criterion states that it becomes essentially difficult to resolve\ntwo incoherent optical point sources separated by a distance below the width of\npoint spread functions (PSF), namely in the subdiffraction limit. Recently,\nres…
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Fault-tolerant and finite-error localization for point emitters within the diffraction limit Open
We implement a self-interference technique for determining the separation between two incoherent point sources. This method relies on image inversion interferometry and when used with the appropriate data analytics, it yields an estimate o…
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Noise reduction in optical coherence tomography images using a deep neural network with perceptually-sensitive loss function Open
Optical coherence tomography (OCT) is susceptible to the coherent noise, which is the speckle noise that deteriorates contrast and the detail structural information of OCT images, thus imposing significant limitations on the diagnostic cap…
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Analyzing Single Molecule Localization Microscopy Data Using Cubic Splines Open
The resolution of super-resolution microscopy based on single molecule localization is in part determined by the accuracy of the localization algorithm. In most published approaches to date this localization is done by fitting an analytica…
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Overcoming the diffraction limit of imaging nanoplasmonic arrays by microspheres and microfibers Open
Super-resolution microscopy by microspheres emerged as a simple and broadband imaging technique; however, the mechanisms of imaging are debated in the literature. Furthermore, the resolution values were estimated based on semi-quantitative…
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Correcting field-dependent aberrations with nanoscale accuracy in three-dimensional single-molecule localization microscopy Open
The localization of single fluorescent molecules enables the imaging of molecular structure and dynamics with subdiffraction precision and can be extended to three dimensions using point spread function (PSF) engineering. However, the nano…
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Inverse Designed Metalenses with Extended Depth of Focus Open
Extended depth of focus (EDOF) lenses are important for various applications in computational imaging and microscopy. In addition to enabling novel functionalities, EDOF lenses can alleviate the need for stringent alignment requirements fo…
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Snapshot‐CEST: Optimizing spiral‐centric‐reordered gradient echo acquisition for fast and robust 3D CEST MRI at 9.4 T Open
Gradient echo (GRE)‐based acquisition provides a robust readout method for chemical exchange saturation transfer (CEST) at ultrahigh field (UHF). To develop a snapshot‐CEST approach, the transient GRE signal and point spread function were …
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Shift-variant color-coded diffractive spectral imaging system Open
State-of-the-art snapshot spectral imaging (SI) systems introduce color-coded apertures (CCAs) into their setups to obtain a flexible spatial-spectral modulation, allowing spectral information to be reconstructed from a set of coded measur…
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Evaluation of Penalized-Likelihood Estimation Reconstruction on a Digital Time-of-Flight PET/CT Scanner for<sup>18</sup>F-FDG Whole-Body Examinations Open
The resolution and quantitative accuracy of PET are highly influenced by the reconstruction method. Penalized-likelihood estimation algorithms allow for fully convergent iterative reconstruction, generating a higher image contrast than ord…
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Improving Axial Resolution in Confocal Microscopy with New High Refractive Index Mounting Media Open
Resolution, high signal intensity and elevated signal to noise ratio (SNR) are key issues for biologists who aim at studying the localisation of biological structures at the cellular and subcellular levels using confocal microscopy. The re…