Complication ≈ Complication
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Clinical Update: Cardiovascular Disease in Diabetes Mellitus Open
Cardiovascular disease remains the principal cause of death and disability among patients with diabetes mellitus. Diabetes mellitus exacerbates mechanisms underlying atherosclerosis and heart failure. Unfortunately, these mechanisms are no…
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Chronic thromboembolic pulmonary hypertension Open
Chronic thromboembolic pulmonary hypertension (CTEPH) is a complication of pulmonary embolism and a major cause of chronic PH leading to right heart failure and death. Lung ventilation/perfusion scintigraphy is the screening test of choice…
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Systematic review of preoperative, intraoperative and postoperative risk factors for colorectal anastomotic leaks Open
Background Anastomotic leak (AL) represents a dreaded complication following colorectal surgery, with a prevalence of 1–19 per cent. There remains a lack of consensus regarding factors that may predispose to AL and the relative risks assoc…
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Euglycemic Diabetic Ketoacidosis: A Potential Complication of Treatment With Sodium–Glucose Cotransporter 2 Inhibition Open
OBJECTIVE Sodium–glucose cotransporter 2 (SGLT-2) inhibitors are the most recently approved antihyperglycemic medications. We sought to describe their association with euglycemic diabetic ketoacidosis (euDKA) in hopes that it will enhance …
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Association Between Wait Time and 30-Day Mortality in Adults Undergoing Hip Fracture Surgery Open
Among adults undergoing hip fracture surgery, increased wait time was associated with a greater risk of 30-day mortality and other complications. A wait time of 24 hours may represent a threshold defining higher risk.
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Cancer-Associated Thrombosis: An Overview of Mechanisms, Risk Factors, and Treatment Open
Cancer-associated thrombosis is a major cause of mortality in cancer patients, the most common type being venous thromboembolism (VTE). Several risk factors for developing VTE also coexist with cancer patients, such as chemotherapy and imm…
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Literature review on the management of diabetic foot ulcer Open
Diabetic foot ulcer (DFU) is the most costly and devastating complication of diabetes mellitus, which affect 15% of diabetic patients during their lifetime. Based on National Institute for Health and Clinical Excellence strategies, early e…
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Diabetic retinopathy - ocular complications of diabetes mellitus Open
In industrialized nations diabetic retinopathy is the most frequent microvascular complication of diabetes mellitus and the most common cause of blindness in the working-age population. In the next 15 years, the number of patients sufferin…
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Radiofrequency Ablation and Microwave Ablation in Liver Tumors: An Update Open
This article provides an overview of radiofrequency ablation (RFA) and microwave ablation (MWA) for treatment of primary liver tumors and hepatic metastasis. Only studies reporting RFA and MWA safety and efficacy on liver were retained. We…
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Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in Acute Ischemic Stroke: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association Open
Purpose— Symptomatic intracranial hemorrhage (sICH) is the most feared complication of intravenous thrombolytic therapy in acute ischemic stroke. Treatment of sICH is based on expert opinion and small case series, with the efficacy of such…
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Safety and Outcomes of the Transoral Endoscopic Thyroidectomy Vestibular Approach Open
The TOETVA was performed as safely as OT, requires only conventional laparoscopic instruments, and avoids incisional scars; thus, the approach may be an option for select patients.
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Ultrasound guidance versus anatomical landmarks for internal jugular vein catheterization Open
Based on available data, we conclude that two-dimensional ultrasound offers gains in safety and quality when compared with an anatomical landmark technique. Because of missing data, we did not compare effects with experienced versus inexpe…
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Heterotopic Ossification: A Comprehensive Review Open
Heterotopic ossification (HO) is a diverse pathologic process, defined as the formation of extraskeletal bone in muscle and soft tissues. HO can be conceptualized as a tissue repair process gone awry and is a common complication of trauma …
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Unintended Return of Consciousness in a Patient during Surgery and General Anesthesia Open
Awareness is an uncommon complication of anaesthesia, affecting 0.1-0.2% of all surgical patients. Bispectral index (BIS) monitoring measures the depth of anaesthesia and facilitates anaesthetic titration. In this trial we determined wheth…
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Post-stroke dysphagia: A review and design considerations for future trials Open
Post-stroke dysphagia (a difficulty in swallowing after a stroke) is a common and expensive complication of acute stroke and is associated with increased mortality, morbidity, and institutionalization due in part to aspiration, pneumonia, …
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Abatacept for Severe Immune Checkpoint Inhibitor–Associated Myocarditis Open
International audience
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Neuropathy and Diabetic Foot Syndrome Open
Diabetic foot ulceration is a serious complication of diabetes mellitus worldwide and the most common cause of hospitalization in diabetic patients. The etiology of diabetic foot ulcerations is complex due to their multifactorial nature; i…
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Ferritin in the coronavirus disease 2019 (COVID‐19): A systematic review and meta‐analysis Open
Objective The coronavirus disease 2019 (COVID‐19) has rapidly developed into a pandemic. Increased levels of ferritin due to cytokine storm and secondary hemophagocytic lymphohistiocytosis were found in severe COVID‐19 patients. Therefore,…
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Surgical approach in primary total hip arthroplasty: anatomy, technique and clinical outcomes Open
Total hip arthroplasty (THA) has revolutionized the treatment of hip arthritis. A number of surgical approaches to the hip joint exist, each with unique advantages and disadvantages. The most commonly used approaches include the direct ant…
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Postoperative atrial fibrillation following cardiac surgery: a persistent complication Open
Postoperative atrial fibrillation (POAF) is a common, expensive and potentially morbid complication following cardiac surgery. POAF occurs in around 35% of cardiac surgery cases and has a peak incidence on postoperative day 2. Patients who…
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COVID-19–Associated Kidney Injury: A Case Series of Kidney Biopsy Findings Open
Significance Statement AKI is a known complication of severe COVID-19. Autopsy series of patients who died with COVID-19 reported acute tubular necrosis in the kidney, and a few patient reports noted the presence of collapsing glomerulopat…
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Complications of Spinal Cord Stimulation and Peripheral Nerve Stimulation Techniques: A Review of the Literature Open
Objective . Spinal cord and peripheral neurostimulation techniques have been practiced since 1967 for the relief of pain, and some techniques are also used for improvement in organ function. Neuromodulation has recognized complications, al…
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Mechanical Complications of Acute Myocardial Infarction: A Scientific Statement From the American Heart Association Open
Over the past few decades, advances in pharmacological, catheter-based, and surgical reperfusion have improved outcomes for patients with acute myocardial infarctions. However, patients with large infarcts or those who do not receive timel…
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Rhabdomyolysis as Potential Late Complication Associated with COVID-19 Open
We describe a patient in Wuhan, China, with severe acute respiratory syndrome coronavirus 2 infection who had progressive pulmonary lesions and rhabdomyolysis with manifestations of lower limb pain and fatigue. Rapid clinical recognition o…
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COVID-19 and pneumothorax: a multicentre retrospective case series Open
Introduction Pneumothorax and pneumomediastinum have both been noted to complicate cases of coronavirus disease 2019 (COVID-19) requiring hospital admission. We report the largest case series yet described of patients with both these patho…
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Consensus guidelines for lumbar puncture in patients with neurological diseases Open
Introduction Cerebrospinal fluid collection by lumbar puncture (LP) is performed in the diagnostic workup of several neurological brain diseases. Reluctance to perform the procedure is among others due to a lack of standards and guidelines…
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Systemic Complications of Acromegaly and the Impact of the Current Treatment Landscape: An Update Open
Acromegaly is a chronic systemic disease with many complications and is associated with increased mortality when not adequately treated. Substantial advances in acromegaly treatment, as well as in the treatment of many of its complications…
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IWGDF guidance on the prevention of foot ulcers in at‐risk patients with diabetes Open
Recommendations To identify a person with diabetes at risk for foot ulceration, examine the feet annually to seek evidence for signs or symptoms of peripheral neuropathy and peripheral artery disease. (GRADE strength of recommendation: str…
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Capsular Contracture after Breast Augmentation: An Update for Clinical Practice Open
Capsular contracture is the most common complication following implant based breast surgery and is one of the most common reasons for reoperation. Therefore, it is important to try and understand why this happens, and what can be done to r…
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Heart Failure: An Underappreciated Complication of Diabetes. A Consensus Report of the American Diabetes Association Open
Heart failure (HF) has been recognized as a common complication of diabetes, with a prevalence of up to 22% in individuals with diabetes and increasing incidence rates. Data also suggest that HF may develop in individuals with diabetes eve…