Aedes ≈ Aedes
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De novo assembly of the <i>Aedes aegypti</i> genome using Hi-C yields chromosome-length scaffolds Open
Hi-C for mosquito genomes Most genomes sequenced today are determined through the generation of short sequenced bits of DNA that are computationally pieced together like a jigsaw puzzle. This has resulted in the need for funds and addition…
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The current and future global distribution and population at risk of dengue Open
Dengue is a mosquito-borne viral infection that has spread throughout the tropical world over the past 60 years and now affects over half the world’s population. The geographical range of dengue is expected to further expand due to ongoing…
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Possible Association Between Zika Virus Infection and Microcephaly — Brazil, 2015 Open
In early 2015, an outbreak of Zika virus, a flavivirus transmitted by Aedes mosquitoes, was identified in northeast Brazil, an area where dengue virus was also circulating. By September, reports of an increase in the number of infants born…
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Global expansion and redistribution of Aedes-borne virus transmission risk with climate change Open
Forecasting the impacts of climate change on Aedes-borne viruses-especially dengue, chikungunya, and Zika-is a key component of public health preparedness. We apply an empirically parameterized model of viral transmission by the vectors Ae…
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Contemporary status of insecticide resistance in the major Aedes vectors of arboviruses infecting humans Open
[This corrects the article DOI: 10.1371/journal.pntd.0005625.].
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Imported chikungunya cases in an area newly colonised by Aedes albopictus: mathematical assessment of the best public health strategy Open
We aimed to identify the optimal strategy that should be used by public health authorities against transmission of chikungunya virus in mainland France. The theoretical model we developed, which mimics the current surveillance system, pred…
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Detecting the impact of temperature on transmission of Zika, dengue, and chikungunya using mechanistic models Open
Recent epidemics of Zika, dengue, and chikungunya have heightened the need to understand the seasonal and geographic range of transmission by Aedes aegypti and Ae. albopictus mosquitoes. We use mechanistic transmission models to derive pre…
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Differential Susceptibilities of Aedes aegypti and Aedes albopictus from the Americas to Zika Virus Open
This study suggests that although susceptible to infection, Ae. aegypti and Ae. albopictus were unexpectedly low competent vectors for ZIKV. This may suggest that other factors such as the large naïve population for ZIKV and the high densi…
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An end-to-end assembly of the Aedes aegypti genome Open
We present an end-to-end genome assembly of a female Aedes aegypti mosquito, which spreads viral diseases such as yellow fever, dengue, chikungunya, and Zika to humans. The assembly is based on an earlier genome published in 2007 and impro…
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Effects of the Environmental Temperature on Aedes aegypti and Aedes albopictus Mosquitoes: A Review Open
The temperature of the environment is one of the most important abiotic factors affecting the life of insects. As poikilotherms, their body temperature is not constant, and they rely on various strategies to minimize the risk of thermal st…
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Dengue in a changing climate Open
Dengue is the world's most important arboviral disease in terms of number of people affected. Over the past 50 years, incidence increased 30-fold: there were approximately 390 million infections in 2010. Globalization, trade, travel, demog…
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Global risk mapping for major diseases transmitted by Aedes aegypti and Aedes albopictus Open
With 215 countries/territories potentially suitable for the most important arboviral disease vectors and more than half of these reporting cases, arboviral diseases are indeed a global public health threat. The increasing proportion of rep…
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Aedes aegypti vector competence studies: A review Open
Aedes aegypti is the primary transmitter of the four viruses that have had the greatest impact on human health, the viruses causing yellow fever, dengue fever, chikungunya, and Zika fever. Because this mosquito is easy to rear in the labor…
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Zika, Chikungunya, and Other Emerging Vector-Borne Viral Diseases Open
Arthropod-borne viruses (arboviruses) have a long history of emerging to infect humans, but during recent decades, they have been spreading more widely and affecting larger populations. This is due to several factors, including increased a…
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Zika, chikungunya and dengue: the causes and threats of new and re-emerging arboviral diseases Open
The recent emergence and re-emergence of viral infections transmitted by vectors—Zika, chikungunya, dengue, Japanese encephalitis, West Nile, yellow fever and others—is a cause for international concern. Using as examples Zika, chikungunya…
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<i>Notes from the Field</i>: Evidence of Zika Virus Infection in Brain and Placental Tissues from Two Congenitally Infected Newborns and Two Fetal Losses — Brazil, 2015 Open
Zika virus is a mosquito-borne flavivirus that is related to dengue virus and transmitted primarily by Aedes aegypti mosquitoes, with humans acting as the principal amplifying host during outbreaks. Zika virus was first reported in Brazil …
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Zika virus-associated neurological disorders: a review Open
Zika virus, an arbovirus transmitted by mosquitoes of the Aedes species, is now rapidly disseminating throughout the Americas and the ongoing Brazilian outbreak is the largest Zika virus epidemic so far described. In addition to being asso…
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Mapping global environmental suitability for Zika virus Open
Zika virus was discovered in Uganda in 1947 and is transmitted by Aedes mosquitoes, which also act as vectors for dengue and chikungunya viruses throughout much of the tropical world. In 2007, an outbreak in the Federated States of Microne…
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Detection of Zika Virus in Semen Open
For nearly 8 decades, N. gonorrhoeae has been controllable.Continued investment in research and the development of new laboratory technology are critical in supporting an effective response to mitigate the threat of untreatable gonorrhea.
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A comparative analysis of prophylactic antimicrobial use in long-term care facilities in Ireland, 2013 and 2016 Open
Long-term care facilities (LTCFs) are \nimportant locations of antimicrobial consumption. Of \nparticular concern is inappropriate prescribing of prophylactic \nantimicrobials. Aim: We aimed to explore \nfactors related to antimicrobial pr…
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Prevention and Control of Zika as a Mosquito-Borne and Sexually Transmitted Disease: A Mathematical Modeling Analysis Open
The ongoing Zika virus (ZIKV) epidemic in the Americas poses a major global public health emergency. While ZIKV is transmitted from human to human by bites of Aedes mosquitoes, recent evidence indicates that ZIKV can also be transmitted vi…
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Alternative strategies for mosquito-borne arbovirus control Open
As the burden of mosquito-borne arboviruses, predominately those transmitted by Aedes aegypti and A. albopictus, continues to grow at a global scale, new vector-control tools and integrated strategies will be required to meet public health…
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The wMel strain of Wolbachia Reduces Transmission of Zika virus by Aedes aegypti Open
Zika virus (ZIKV) is causing an explosive outbreak of febrile disease in the Americas. There are no effective antiviral therapies or licensed vaccines for this virus and mosquito control strategies have not been adequate to contain the vir…
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Management of insecticide resistance in the major Aedes vectors of arboviruses: Advances and challenges Open
Although IRM should be a fixture of all vector control programs, it is currently often absent from the strategic plans to control mosquito-borne diseases, especially arboviruses. Experiences from other public health disease vectors and agr…
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Mosquito Oviposition Behavior and Vector Control Open
The burden of gene transfer from one mosquito generation to the next falls on the female and her eggs. The selection of an oviposition site that guarantees egg and larval survival is a critical step in the reproductive process. The dangers…
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Aedes Mosquitoes and Aedes-Borne Arboviruses in Africa: Current and Future Threats Open
The Zika crisis drew attention to the long-overlooked problem of arboviruses transmitted by Aedes mosquitoes in Africa. Yellow fever, dengue, chikungunya and Zika are poorly controlled in Africa and often go unrecognized. However, to comba…
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Dengue virus: A global human threat: Review of literature Open
Dengue is an acute viral illness caused by RNA virus of the family Flaviviridae and spread by Aedes mosquitoes. Presenting features may range from asymptomatic fever to dreaded complications such as hemorrhagic fever and shock. A cute-onse…
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The role of urbanisation in the spread of Aedes mosquitoes and the diseases they transmit—A systematic review Open
Background This systematic review aims to assess how different urbanisation patterns related to rapid urban growth, unplanned expansion, and human population density affect the establishment and distribution of Aedes aegypti and Aedes albo…
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Mapping the global potential distributions of two arboviral vectors Aedes aegypti and Ae. albopictus under changing climate Open
BackgroundAedes aegypti and Ae. albopictus are the primary vectors that transmit several arboviral diseases, including dengue, chikungunya, and Zika. The world is presently experiencing a series of outbreaks of these diseases, so, we still…
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Wolbachia Infections in Aedes aegypti Differ Markedly in Their Response to Cyclical Heat Stress Open
Aedes aegypti mosquitoes infected with Wolbachia bacteria are currently being released for arbovirus suppression around the world. Their potential to invade populations and persist will depend on interactions with environmental conditions,…