Alcohol consumption
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Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries Open
Heavy alcohol consumption is an established risk factor for hypertension; the mechanism by which alcohol consumption impact blood pressure (BP) regulation remains unknown. We hypothesized that a genome-wide association study accounting for…
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A Review of Colorectal Cancer in Terms of Epidemiology, Risk Factors, Development, Symptoms and Diagnosis Open
This review article contains a concise consideration of genetic and environmental risk factors for colorectal cancer. Known risk factors associated with colorectal cancer include familial and hereditary factors and lifestyle-related and ec…
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Gender Differences in the Epidemiology of Alcohol Use and Related Harms in the United States Open
Over the past century, differences in alcohol use and related harms between males and females in the United States have diminished considerably. In general, males still consume more alcohol and experience and cause more alcohol-related inj…
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Oral cancer: Etiology and risk factors: A review Open
Oral cancer is the sixth most common malignancy in the world. Oral cancer is of major concern in Southeast Asia primarily because of the prevalent oral habits of betel quid chewing, smoking, and alcohol consumption. Despite recent advances…
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The effect of a reduction in alcohol consumption on blood pressure: a systematic review and meta-analysis Open
National Institute on Alcohol Abuse and Alcoholism of the National Institutes of Health (NIH).
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Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations Open
Alcohol consumption level and alcohol use disorder (AUD) diagnosis are moderately heritable traits. We conduct genome-wide association studies of these traits using longitudinal Alcohol Use Disorder Identification Test-Consumption (AUDIT-C…
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Moderate alcohol consumption as risk factor for adverse brain outcomes and cognitive decline: longitudinal cohort study Open
Objectives To investigate whether moderate alcohol consumption has a favourable or adverse association or no association with brain structure and function.Design Observational cohort study with weekly alcohol intake and cognitive performan…
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Governmental standard drink definitions and low‐risk alcohol consumption guidelines in 37 countries Open
Background and Aims One of the challenges of international alcohol research and policy is the variability in and lack of knowledge of how governments in different nations define a standard drink and low‐risk drinking. This study gathered s…
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Alcohol Consumption in Response to the COVID-19 Pandemic in the United States Open
Objectives: Excessive alcohol use is a serious and growing public health problem. Alcoholic beverage sales in the United States increased greatly immediately after the stay-at-home orders and relaxing of alcohol restrictions associated wit…
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Immediate impact of minimum unit pricing on alcohol purchases in Scotland: controlled interrupted time series analysis for 2015-18 Open
Objective To assess the immediate impact of the introduction of minimum unit pricing in Scotland on household alcohol purchases. Design Controlled interrupted time series analysis. Setting Purchase data from Kantar Worldpanel’s household s…
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Alcohol consumption and risk of dementia: 23 year follow-up of Whitehall II cohort study Open
The risk of dementia was increased in people who abstained from alcohol in midlife or consumed >14 units/week. In several countries, guidelines define thresholds for harmful alcohol consumption much higher than 14 units/week. The present f…
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No level of alcohol consumption improves health Open
First paragraph: By use of methodological enhancements of previous iterations, 1 the systematic analysis from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 for 195 countries and territories, 1990–2016, 2 is the…
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COVID-19 Confinement and Health Risk Behaviors in Spain Open
The World Health Organization (WHO) has declared a world pandemic due to COVID-19. In response, most affected countries have enacted measures involving compulsory confinement and restrictions on free movement, which likely influence citize…
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<i>KLB</i> is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference Open
Significance Alcohol is a widely consumed drug in western societies that can lead to addiction. A small shift in consumption can have dramatic consequences on public health. We performed the largest genome-wide association metaanalysis and…
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Positive and Negative Changes in Food Habits, Physical Activity Patterns, and Weight Status during COVID-19 Confinement: Associated Factors in the Chilean Population Open
The association between the changes in lifestyle during coronavirus disease 2019 (COVID-19) confinement and body weight have not been studied deeply. Therefore, the aim of the present study was to determine lifestyle changes, such as eatin…
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Episodic Future Thinking: Expansion of the Temporal Window in Individuals with Alcohol Dependence Open
Together, these results suggest a widening of alcohol-dependent individuals' temporal window following engagement of EFT. While our data suggest that EFT may be moderated by certain susceptibility criteria, exercises such as EFT could be e…
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Hypertriglyceridemic pancreatitis: Epidemiology, pathophysiology and clinical management Open
Hypertriglyceridemic pancreatitis (HTGP) typically occurs in patients with an underlying dyslipidemia (such as type I, IV or V dyslipidemia) and in the presence of a secondary condition, such as inadequately controlled diabetes, excess alc…
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Alcohol Consumption in Demographic Subpopulations: An Epidemiologic Overview Open
Alcohol consumption is common across subpopulations in the United States. However, the health burden associated with alcohol consumption varies across groups, including those defined by demographic characteristics such as age, race/ ethnic…
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Trends in Alcohol Consumption Among Older Americans: National Health Interview Surveys, 1997 to 2014 Open
Background The majority of U.S. older adults consume alcoholic beverages. The older population is projected to almost double by 2050. Substantially more drinkers are likely. Purpose To describe gender‐specific trends (1997 to 2014) in prev…
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Is There a Recent Epidemic of Women's Drinking? A Critical Review of National Studies Open
Alcohol consumption is increasing in the United States, as is alcohol‐attributable mortality. Historically, men have had higher rates of alcohol consumption than women, though evidence for birth cohort effects on gender differences in alco…
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Meta‐Analysis of the Association of Alcohol‐Related Social Media Use with Alcohol Consumption and Alcohol‐Related Problems in Adolescents and Young Adults Open
Despite the pervasive use of social media by young adults, there is comparatively little known about whether, and how, engagement in social media influences this group's drinking patterns and risk of alcohol‐related problems. We examined t…
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Apparent Per Capita Alcohol Consumption: National, State, and Regional Trends 1977-2016 Open
This data set contains the per capita (persons aged 14+) consumption of ethanol (in gallons) for each state and Washington D.C. for the years 1977-2016. This includes total ethanol consumed as well as consumption by three categories: beer,…
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Comparison of pharmaceutical, illicit drug, alcohol, nicotine and caffeine levels in wastewater with sale, seizure and consumption data for 8 European cities Open
This work confirms the promising future of WBE as a complementary approach to obtain a more accurate picture of substance use situation within different communities. Our findings suggest further improvements to reduce the uncertainties ass…
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Sex‐Specific Associations Between Alcohol Consumption and Incidence of Hypertension: A Systematic Review and Meta‐Analysis of Cohort Studies Open
Background Although it is well established that heavy alcohol consumption increases the risk of hypertension, the risk associated with low levels of alcohol intake in men and women is unclear. Methods and Results We searched Medline and Em…
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Alcohol consumption during the COVID‐19 pandemic in Europe: a large‐scale cross‐sectional study in 21 countries Open
Aims To investigate changes in alcohol consumption during the first months of the COVID‐19 pandemic in Europe as well as its associations with income and experiences of distress related to the pandemic. Design Cross‐sectional on‐line surve…
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Benefits and Risks of Moderate Alcohol Consumption on Cardiovascular Disease: Current Findings and Controversies Open
Alcohol has a hormetic physiological behavior that results in either increased or decreased cardiovascular risk depending on the amount consumed, drinking frequency, pattern of consumption, and the outcomes under study or even the type of …
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Gene-environment interaction study for BMI reveals interactions between genetic factors and physical activity, alcohol consumption and socioeconomic status Open
Previous genome-wide association studies (GWAS) have identified hundreds of genetic loci to be associated with body mass index (BMI) and risk of obesity. Genetic effects can differ between individuals depending on lifestyle or environmenta…
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Ethyl glucuronide in hair detects a high rate of harmful alcohol consumption in presumed non-alcoholic fatty liver disease Open
Fatty liver disease can be caused by metabolic factors and/or alcohol consumption. The diagnosis of non-alcoholic fatty liver disease (NAFLD) is based on the exclusion of harmful alcohol consumption, while metabolic dysfunction-associated …
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Sex differences in hypertension prevalence and control: Analysis of the 2010-2014 Korea National Health and Nutrition Examination Survey Open
Although not fully understood, sex may affect both the prevalence and control rate of hypertension. The present study was designed to investigate factors associated with hypertension prevalence and control among Korean adults. We analyzed …
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Multiple novel gene-by-environment interactions modify the effect of FTO variants on body mass index Open
Genetic studies have shown that obesity risk is heritable and that, of the many common variants now associated with body mass index, those in an intron of the fat mass and obesity-associated ( FTO ) gene have the largest effect. The size o…