Ketamine hydrochloride
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Efficacy of ketamine therapy in the treatment of depression Open
Ketamine has a robust and rapid effect on depression, which was seen immediately after the administration of ketamine and sustained at the end of 1 month.
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Oral Ketamine vs Placebo in Patients With Cancer-Related Neuropathic Pain Open
Ketamine hydrochloride is used as an adjuvant treatment for cancer-related neuropathic pain, but evidence of its effectiveness is limited.1 Findings of a large trial investigating the use of ketamine for general cancer pain were negative, …
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Brain targeted oral delivery of doxycycline hydrochloride encapsulated Tween 80 coated chitosan nanoparticles against ketamine induced psychosis: behavioral, biochemical, neurochemical and histological alterations in mice Open
To develop statistically optimized brain targeted Tween 80 coated chitosan nanoparticulate formulation for oral delivery of doxycycline hydrochloride for the treatment of psychosis and to evaluate its protective effect on ketamine induced …
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Moxifloxacin Hydrochloride Electrochemical Detection at Gold Nanoparticles Modified Screen-Printed Electrode Open
It appeared that either the carbon paste or the screen-printed carbon electrodes that were modified with gold nanoparticles (AuNPs) gave rise to the largest current responses after a rapid screening of various nanomaterials as modifiers of…
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Furfural and 5-HMF: Potent fermentation inhibitors and their removal techniques Open
The objective of this study to find out the effect of ketamine in combination of opioids on haemodianamics and electrocardiograph in dogs.The ketamine hydrochloride @3mg/kg bwt was administered epidurally at lumbosacrcal space in group I, …
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Evaluation of urinary bladder fibrogenesis in a mouse model of long-term ketamine injection Open
Long-term ketamine abuse has been shown to affect the lower urinary tract and result in interstitial cystitis-like syndrome. However, the causative mechanism of ketamine-induced dysfunction remains unclear. The present study aimed to inves…
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Quality of domestic cat semen collected by urethral catheterization after the use of different alpha 2-adrenergic agonists Open
Objectives We compared the effects of two alpha (α) 2 -adrenergic agonists on semen traits. Methods In this study, 13 adult domestic cats were divided into two experimental groups, according to the chemical ejaculation protocol used: the f…
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Measuring behavioral and physiological responses to pain mitigation for ovariectomy in Bos taurus yearling beef heifers Open
Ovariectomy (spaying) using the trans-vaginal dropped ovary technique (DOT) is performed to prevent pregnancy in cull female beef cattle that are not retained for breeding stock in areas practicing extensive grazing management. There are n…
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Continuous Rate Infusion of Ketamine Hydrochloride and Dexmedetomidine for Maintenance of Anesthesia during Laryngotracheal Surgery in New Zealand White Rabbits (<i>Oryctolagus cuniculus</i>) Open
New Zealand white rabbits ( Oryctolagus cuniculus ) are an established in vivo model for the study of structural and functional consequences of vocal-fold vibration. Research design requires invasive laryngotracheal procedures, and the pre…
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Drug Residues after Intravenous Anesthesia and Intrathecal Lidocaine Hydrochloride Euthanasia in Horses Open
Background Intrathecal lidocaine hydrochloride under general anesthesia has been used as an alternative method of euthanasia in equids. Carnivore, scavenger, and even human consumption of horse meat from carcasses have been anecdotally rep…
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Analgesic Effects of Ketamine, Magnesium Sulfate, and Sodium-Thiopental on Propofol Injection Pain: A Single-Blind Randomized Clinical Trial. Open
Ketamine and sodium-thiopental can be effective medications in reducing pain caused by propofol injection. According to the results, magnesium sulfate is not recommended for reducing pain due to propofol injection.
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Comparison of two sedation protocols for short electroretinography in cats Open
Objectives The objectives were to compare two different sedative combinations, xylazine–ketamine and dexmedetomidine–ketamine, for the short electroretinography (ERG) protocol and their impact on sedative effect, reversal times and physiol…
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Evaluation of the effect of perioperative administration of S(+)-ketamine hydrochloride injection for postoperative acute pain in children: study protocol for a prospective, multicenter, randomized, open-label, parallel-group, pragmatic clinical trial Open
Background Inadequate postoperative pain management increases the risk of adverse events after the surgery and aggressive perioperative pain prevention has both short-term and long-term benefits. S(+)-ketamine is an N-methyl-D-aspartic aci…
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Does an interaction exist between ketamine hydrochloride and Becton Dickinson syringes? Open
In our study conditions, ketamine can be stored for at least 50 days without risk of sorption with syringes.
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Pudendal Nerve Block in Male Goats: Comparison of Ischiorectal Fossa and Ischial Arch Approaches Using Low Volume 1% Lignocaine Hydrochloride Open
Thirty (30) adult male goats were injected xylazine (0.05 mg/kg, IM) and randomly divided into three equal groups. Internal pudendal nerve block was tried using 3.5 ml (on each side) of 1% lignocaine hydrochloride byischiorectal fossa or i…
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Physicochemical stability of ternary admixtures of butorphanol, ketamine, and droperidol in polyolefin bags for patient-controlled analgesia use Open
The results confirm that the ternary admixture of butorphanol tartrate 0.067 mg/mL, ketamine hydrochloride 1.33 mg/mL, and droperidol 0.033 mg/mL in 0.9% sodium chloride injection were stable for 14 days when stored in polyolefin bags at 4…
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Ketamine as an adjunctive therapy for major depression - a randomised controlled pragmatic pilot trial (Karma-Dep Trial) Open
Background: Depression is a common psychiatric disorder that has become the leading cause of disability worldwide. The standard medical care for depression over the past 50 years has focused on monoamine neurotransmitters. These treatments…
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Histopathology and Histomorphological Study of Wound Healing Using Clove Extract Nanofibers (Eugenol) Compared to Zinc Oxide Nanofibers on the Skin of Rats. Open
In order to evaluate the healing effect of eugenol and other nanofibers, 100 male Wistar rats (200±10 g) were used with 14-15 weeks of age in this study. All of the male rats were transferred in the standard cages under controlled exposure…
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Clinical effect of acupuncture at ghost points combined with fluoxetine hydrochloride on mild-to-moderate depression Open
BACKGROUND Depression is a common, chronic, and recurrent mood disorder that has become a worldwide health hazard. Fluoxetine hydrochloride, a common treatment method, can inhibit 5-hydroxytryptamine (5-HT) recycling in the presynaptic mem…
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Clinical Evaluation of General Anaesthesia using Ketamine Hydrochloride with and without Diazepam in Sheep Open
The study has been carried out to evaluate the clinical efficacy of ketamine with or without diazepam in sheep. Six healthy sheep were used in this study and randomly divided into two groups; Group A (atropine-diazepam-ketamine) and Group …
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Chemical immobilisation of dhole (<i>Cuon alpinus</i>), Indian jackal (<i>Canis aureus indicus</i>) and Indian wolf (<i>Canis lupus pallipes</i>) with ketamine hydrochloride–xylazine hydrochloride Open
Maintaining wild animals in captivity often requires chemical immobilisation to achieve various diagnostic, surgical and management interventions. Four dholes, two Indian grey wolves and four Indian jackals were immobilised using ketamine–…
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Prolonged Codeine Administration Causes Degeneration of Myelinated Axons and Motor Dysfunction in Wistar Rats Open
Prolonged consumption of prescription codeine causes degeneration of the myelin sheaths and this may affect the conduction of electrical impulses in myelinated axons thus resulting in motor function insufficiency.
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Cardiovascular effects of continuous rate infusion of lignocaine as an adjunct to general anaesthesia for intestinal surgery in cattle Open
The study was carried out in 12 clinical cases of cattle to assess the cardiovascular effects of intravenous continuous rate infusion of lignocaine as an adjunct to general anaesthesia for intestinal surgeries. The animals were indiscrimin…
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Detection of Grasserie Virus, BmNPV in the Fifth Instar Larvae of Silkworm, Bombyx mori (L) (Race: PM x CSR2) Through Polymerase Chain Reaction Open
The objective of this study to find out the effect of ketamine in combination of opioids on haemodianamics and electrocardiograph in dogs. The ketamine hydrochloride @3mg/kg bwt was administered epidurally at lumbosacrcal space in group I,…
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Ketamine as an adjunctive therapy for major depression - a randomised controlled pragmatic pilot trial (Karma-Dep Trial) Open
Background: Depression is a common psychiatric disorder that has become the leading cause of disability worldwide. The standard medical care for depression over the past 50 years has focused on monoamine neurotransmitters. These treatments…
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Fabrication of an electrochemical impedance sensor for ketamine hydrochloride and its application in the detection of doping substances in sports Open
This work reports an ultrasensitive impedimetric immunosensor for ketamine detection using self-assembled monolayers of 3-mercaptopropionic acid on gold electrodes. Monoclonal ketamine antibodies were covalently tethered via EDC/NHS crossl…
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Analyzing Turning Behavior after Repeated Lithium, Ketamine, or NaCl Injection and Chronic Stress Exposure in Mice Open
A single chronic stress is often considered a potential reinforcer in psychiatric disorders. Lithium and ketamine both seem to ameliorate the consequences of stress. Here, male mice were either injected with lithium carbonate (LiCl), ketam…
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Sedation with Propofol and Propofol–Ketamine (Ketofol) in Flexible Bronchoscopy: A Randomized, Double-Blind, Prospective Study Open
Background: The flexible bronchoscopy procedure, which is performed in awake conditions or under local anesthesia, is a difficult and complicated procedure for patients and physicians. Propofol is a fast-acting sedative-hypnotic anesthetic…
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Ketamine Inhalation Alters Behavior and Lower Urinary Tract Function in Mice Open
We aimed to evaluate behavioral and lower urinary tract changes in mice using a novel ketamine inhalation model mimicking human ketamine abusers and compare the results to those obtained using a ketamine intraperitoneal injection model. C5…
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Comparative Evaluation of the Biochemical Effects of Ketamine plus Ketoprofen and Midazolam in the Premedication of Pigeons. Open
The present study was conducted with the aim of comparing the effects of premedication with ketoprofen and midazolam in birds. A total of 24 male pigeons with an approximate weight of 300 g were divided into four equal groups. The control …