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View article: RoB 2: a revised tool for assessing risk of bias in randomised trials
RoB 2: a revised tool for assessing risk of bias in randomised trials Open
Assessment of risk of bias is regarded as an essential component of a systematic review on the effects of an intervention. The most commonly used tool for randomised trials is the Cochrane risk-of-bias tool. We updated the tool to respond …
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The PRISMA 2020 statement: An updated guideline for reporting systematic reviews Open
The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement, published in 2009, was designed to help systematic reviewers transparently report why the review was done, what the authors did, and what they found…
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The Eighth Edition <span>AJCC</span> Cancer Staging Manual: Continuing to build a bridge from a population‐based to a more “personalized” approach to cancer staging Open
The American Joint Committee on Cancer (AJCC) staging manual has become the benchmark for classifying patients with cancer, defining prognosis, and determining the best treatment approaches. Many view the primary role of the tumor, lymph n…
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The PRISMA 2020 statement: An updated guideline for reporting systematic reviews Open
Matthew Page and co-authors describe PRISMA 2020, an updated reporting guideline for systematic reviews and meta-analyses.
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International Classification of Diseases for Oncology Open
T he International Classification of Diseases for Oncology has been used for nearly 25 years as a tool for coding diagnoses of neoplasms in tumor and cancer registrars and in pathology laboratories.ICD-O is a dual classification with codin…
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The PRISMA 2020 statement: An updated guideline for reporting systematic reviews Open
The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement, published in 2009, was designed to help systematic reviewers transparently report why the review was done, what the authors did, and what they found…
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Assessment of Clinical Criteria for Sepsis Open
Among ICU encounters with suspected infection, the predictive validity for in-hospital mortality of SOFA was not significantly different than the more complex LODS but was statistically greater than SIRS and qSOFA, supporting its use in cl…
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The Image Biomarker Standardization Initiative: Standardized Quantitative Radiomics for High-Throughput Image-based Phenotyping Open
Background Radiomic features may quantify characteristics present in medical imaging. However, the lack of standardized definitions and validated reference values have hampered clinical use. Purpose To standardize a set of 174 radiomic fea…
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The STROBE guidelines Open
An observational study is a type of epidemiological study design, which can take the form of a cohort, a case-control, or a cross-sectional study. When presenting observational studies in manuscripts, an author needs to ascertain a clear p…
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Predicting the Future — Big Data, Machine Learning, and Clinical Medicine Open
The algorithms of machine learning, which can sift through vast numbers of variables looking for combinations that reliably predict outcomes, will improve prognosis, displace much of the work of radiologists and anatomical pathologists, an…
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COVID-Net: a tailored deep convolutional neural network design for detection of COVID-19 cases from chest X-ray images Open
The Coronavirus Disease 2019 (COVID-19) pandemic continues to have a devastating effect on the health and well-being of the global population. A critical step in the fight against COVID-19 is effective screening of infected patients, with …
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CONSORT 2010 statement: extension to randomised pilot and feasibility trials Open
The CONSORT Statement (CONsolidated Standards for Reporting Trials) is a reporting guideline designed to improve the transparency and quality of the reporting of randomised controlled trials (RCTs). In this article, we present an extension…
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Preferred Reporting Items for a Systematic Review and Meta-analysis of Diagnostic Test Accuracy Studies Open
The 27-item PRISMA diagnostic test accuracy checklist provides specific guidance for reporting of systematic reviews. The PRISMA diagnostic test accuracy guideline can facilitate the transparent reporting of reviews, and may assist in the …
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STARD 2015 guidelines for reporting diagnostic accuracy studies: explanation and elaboration Open
Diagnostic accuracy studies are, like other clinical studies, at risk of bias due to shortcomings in design and conduct, and the results of a diagnostic accuracy study may not apply to other patient groups and settings. Readers of study re…
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Guidelines for Perioperative Care in Elective Colorectal Surgery: Enhanced Recovery After Surgery (ERAS<sup>®</sup>) Society Recommendations: 2018 Open
Background This is the fourth updated Enhanced Recovery After Surgery (ERAS ® ) Society guideline presenting a consensus for optimal perioperative care in colorectal surgery and providing graded recommendations for each ERAS item within th…
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A new classification scheme for periodontal and peri‐implant diseases and conditions – Introduction and key changes from the 1999 classification Open
A classification scheme for periodontal and peri‐implant diseases and conditions is necessary for clinicians to properly diagnose and treat patients as well as for scientists to investigate etiology, pathogenesis, natural history, and trea…
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Guidelines for Limiting Exposure to Electromagnetic Fields (100 kHz to 300 GHz) Open
Radiofrequency electromagnetic fields (EMFs) are used to enable a number of modern devices, including mobile telecommunications infrastructure and phones, Wi-Fi, and Bluetooth. As radiofrequency EMFs at sufficiently high power levels can a…
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Artificial intelligence in cancer imaging: Clinical challenges and applications Open
Judgement, as one of the core tenets of medicine, relies upon the integration of multilayered data with nuanced decision making. Cancer offers a unique context for medical decisions given not only its variegated forms with evolution of dis…
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Ultrasound Elastography: Review of Techniques and Clinical Applications Open
Elastography-based imaging techniques have received substantial attention in recent years for non-invasive assessment of tissue mechanical properties. These techniques take advantage of changed soft tissue elasticity in various pathologies…
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ECCO-ESGAR Guideline for Diagnostic Assessment in IBD Part 1: Initial diagnosis, monitoring of known IBD, detection of complications Open
This new diagnostic consensus guideline is a joint project of the European Crohn’s and Colitis Organisation [ECCO] and the European Society of Gastrointestinal and Abdominal Radiology [ESGAR] that now merges the former ECCO-ESGAR Imaging G…
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European guidance for the diagnosis and management of osteoporosis in postmenopausal women Open
peer reviewed
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Nanoparticles in the clinic: An update Open
Nanoparticle drug delivery systems have been used in the clinic since the early 1990's. Since that time, the field of nanomedicine has evolved alongside growing technological needs to improve the delivery of various therapeutics. Over thes…
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Introduction to Radiomics Open
Radiomics is a rapidly evolving field of research concerned with the extraction of quantitative metrics-the so-called radiomic features-within medical images. Radiomic features capture tissue and lesion characteristics such as heterogeneit…
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Standardization of left atrial, right ventricular, and right atrial deformation imaging using two-dimensional speckle tracking echocardiography: a consensus document of the EACVI/ASE/Industry Task Force to standardize deformation imaging Open
The EACVI/ASE/Industry Task Force to standardize deformation imaging prepared this consensus document to standardize definitions and techniques for using two-dimensional (2D) speckle tracking echocardiography (STE) to assess left atrial, r…
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A new classification scheme for periodontal and peri‐implant diseases and conditions – Introduction and key changes from the 1999 classification Open
A classification scheme for periodontal and peri‐implant diseases and conditions is necessary for clinicians to properly diagnose and treat patients as well as for scientists to investigate etiology, pathogenesis, natural history, and trea…
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CheXNet: Radiologist-Level Pneumonia Detection on Chest X-Rays with Deep\n Learning Open
We develop an algorithm that can detect pneumonia from chest X-rays at a\nlevel exceeding practicing radiologists. Our algorithm, CheXNet, is a 121-layer\nconvolutional neural network trained on ChestX-ray14, currently the largest\npublicl…
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CheXNet: Radiologist-Level Pneumonia Detection on Chest X-Rays with Deep Learning Open
We develop an algorithm that can detect pneumonia from chest X-rays at a level exceeding practicing radiologists. Our algorithm, CheXNet, is a 121-layer convolutional neural network trained on ChestX-ray14, currently the largest publicly a…
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Deep learning for chest radiograph diagnosis: A retrospective comparison of the CheXNeXt algorithm to practicing radiologists Open
In this study, we developed and validated a deep learning algorithm that classified clinically important abnormalities in chest radiographs at a performance level comparable to practicing radiologists. Once tested prospectively in clinical…
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ERS/ATS technical standard on interpretive strategies for routine lung function tests Open
Background Appropriate interpretation of pulmonary function tests (PFTs) involves the classification of observed values as within/outside the normal range based on a reference population of healthy individuals, integrating knowledge of phy…
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Applications and limitations of radiomics Open
Radiomics is an emerging field in quantitative imaging that uses advanced imaging features to objectively and quantitatively describe tumour phenotypes. Radiomic features have recently drawn considerable interest due to its potential predi…