View article: ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions
ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions Open
Non-randomised studies of the effects of interventions are critical to many areas of healthcare evaluation, but their results may be biased. It is therefore important to understand and appraise their strengths and weaknesses. We developed …
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An interactive web-based dashboard to track COVID-19 in real time Open
In December, 2019, a local outbreak of pneumonia of initially unknown cause was detected in Wuhan (Hubei, China), and was quickly determined to be caused by a novel coronavirus,1WHOWHO statement regarding cluster of pneumonia cases in Wuha…
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Immediate Psychological Responses and Associated Factors during the Initial Stage of the 2019 Coronavirus Disease (COVID-19) Epidemic among the General Population in China Open
Background: The 2019 coronavirus disease (COVID-19) epidemic is a public health emergency of international concern and poses a challenge to psychological resilience. Research data are needed to develop evidence-driven strategies to reduce …
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AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both Open
The number of published systematic reviews of studies of healthcare interventions has increased rapidly and these are used extensively for clinical and policy decisions. Systematic reviews are subject to a range of biases and increasingly …
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IDF Diabetes Atlas: Global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045 Open
Just over half a billion people are living with diabetes worldwide which means that over 10.5% of the world's adult population now have this condition.
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Nursing Research - Generating And Assessing Evidence For Nursing Practice Open
Thoroughly updated and revised to emphasize the link between research and evidence-based practice, this Ninth Edition of a classic textbook presents state-of-the-art methods for conducting high-quality studies. The ancillary Resource Manua…
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2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk Open
Prepared by The Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS) \n
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Updated guidance for trusted systematic reviews: a new edition of the Cochrane Handbook for Systematic Reviews of Interventions Open
On a shelf in the sunny, open‐plan office of Cochrane Australia in Melbourne, there's a large, white ring‐binder that, it's fair to say, hasn't been opened in a while. It's a printed copy of the original, 1994 edition of the Cochrane Colla…
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2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS Open
sponsorship: Department of Health|CDF-2015-08-074, British Heart Foundation|FS/13/43/30324, British Heart Foundation|RG/11/15/29375
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2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS Open
peer reviewed
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2021 ESC Guidelines on cardiovascular disease prevention in clinical practice Open
International audience
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AutoDock Vina 1.2.0: New Docking Methods, Expanded Force Field, and Python Bindings Open
AutoDock Vina is arguably one of the fastest and most widely used open-source programs for molecular docking. However, compared to other programs in the AutoDock Suite, it lacks support for modeling specific features such as macrocycles or…
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A new framework for developing and evaluating complex interventions: update of Medical Research Council guidance Open
The UK Medical Research Council’s widely used guidance for developing and evaluating complex interventions has been replaced by a new framework, commissioned jointly by the Medical Research Council and the National Institute for Health Res…
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CDC Guideline for Prescribing Opioids for Chronic Pain—United States, 2016 Open
The guideline is intended to improve communication about benefits and risks of opioids for chronic pain, improve safety and effectiveness of pain treatment, and reduce risks associated with long-term opioid therapy.
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2019 ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD Open
2019 ESC Guidelines on Diabetes, Pre-Diabetes and Cardiovascular Diseases developed in collaboration with the EASD
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Can Treatment Adherence Be Improved by Using Rubin's Four Tendencies Framework to Understand a Patient's Response to Expectations Open
Within the context of poorer patient outcomes and rising healthcare costs, we need to better understand why many patients do not engage fully with their treatment plan. Movement away from talking about “compliance” towards “adherence” and …
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Report 9: Impact of non-pharmaceutical interventions (NPIs) to reduce COVID19 mortality and healthcare demand Open
The global impact of COVID-19 has been profound, and the public health threat it represents is the most serious seen in a respiratory virus since the 1918 H1N1 influenza pandemic. Here we present the results of epidemiological modelling wh…
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Acceptability of healthcare interventions: an overview of reviews and development of a theoretical framework Open
Despite frequent claims that healthcare interventions have assessed acceptability, it is evident that acceptability research could be more robust. The proposed definition of acceptability and the TFA can inform assessment tools and evaluat…
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Synthesis without meta-analysis (SWiM) in systematic reviews: reporting guideline Open
In systematic reviews that lack data amenable to meta-analysis, alternative synthesis methods are commonly used, but these methods are rarely reported. This lack of transparency in the methods can cast doubt on the validity of the review f…
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Nextstrain: real-time tracking of pathogen evolution Open
Summary Understanding the spread and evolution of pathogens is important for effective public health measures and surveillance. Nextstrain consists of a database of viral genomes, a bioinformatics pipeline for phylodynamics analysis, and a…
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Knowledge, attitudes, and practices towards COVID-19 among Chinese residents during the rapid rise period of the COVID-19 outbreak: a quick online cross-sectional survey Open
Unprecedented measures have been adopted to control the rapid spread of the ongoing COVID-19 epidemic in China. People's adherence to control measures is affected by their knowledge, attitudes, and practices (KAP) towards COVID-19. In this…
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2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS) Open
Endorsed by: the European Stroke Organization (ESO), The Task Force for the Diagnosis and Treatment of Peripheral Arterial Diseases of the European Society of Cardiology (ESC) and of the European Society for Vascular Surgery (ESVS)
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The outbreak of COVID-19 coronavirus and its impact on global mental health Open
Background: The current outbreak of COVID-19 coronavirus infection among humans in Wuhan (China) and its spreading around the globe is heavily impacting on the global health and mental health. Despite all resources employed to counteract t…
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Interventions for preventing obesity in children Open
Interventions that include diet combined with physical activity interventions can reduce the risk of obesity (zBMI and BMI) in young children aged 0 to 5 years. There is weaker evidence from a single study that dietary interventions may be…
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2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS Open
International audience
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Interrupted time series regression for the evaluation of public health interventions: a tutorial Open
Interrupted time series (ITS) analysis is a valuable study design for evaluating the effectiveness of population-level health interventions that have been implemented at a clearly defined point in time. It is increasingly being used to eva…
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Isolation, quarantine, social distancing and community containment: pivotal role for old-style public health measures in the novel coronavirus (2019-nCoV) outbreak Open
Public health measures were decisive in controlling the SARS epidemic in 2003. Isolation is the separation of ill persons from non-infected persons. Quarantine is movement restriction, often with fever surveillance, of contacts when it is …
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Recommendations for Conduct, Methodological Practices, and Reporting of Cost-effectiveness Analyses Open
The Second Panel reviewed the current status of the field of cost-effectiveness analysis and developed a new set of recommendations. Major changes include the recommendation to perform analyses from 2 reference case perspectives and to pro…
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Implementing an Antibiotic Stewardship Program: Guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America Open
Evidence-based guidelines for implementation and measurement of antibiotic stewardship interventions in inpatient populations including long-term care were prepared by a multidisciplinary expert panel of the Infectious Diseases Society of …
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The Determinants of Quality of Life of Nursing Home Residents with Young-Onset Dementia and the Differences between Dementia Subtypes Open
Aims: The aims of this study are to (1) explore the determinants of quality of life (QoL) in nursing home residents with young-onset dementia (YOD), (2) investigate whether there are differences between dementia subtypes (Alzheimer dementi…