Surgery ≈ Surgery
View article: Cancer statistics, 2019
Cancer statistics, 2019 Open
Each year, the American Cancer Society estimates the numbers of new cancer cases and deaths that will occur in the United States and compiles the most recent data on cancer incidence, mortality, and survival. Incidence data, available thro…
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Undervaccination and severe COVID-19 outcomes: meta-analysis of national cohort studies in England, Northern Ireland, Scotland, and Wales Open
Summary Background Undervaccination (receiving fewer than the recommended number of SARS-CoV-2 vaccine doses) could be associated with increased risk of severe COVID-19 outcomes—ie, COVID-19 hospitalisation or death—compared with full vacc…
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An interactive web-based dashboard to track COVID-19 in real time Open
In December, 2019, a local outbreak of pneumonia of initially unknown cause was detected in Wuhan (Hubei, China), and was quickly determined to be caused by a novel coronavirus,1WHOWHO statement regarding cluster of pneumonia cases in Wuha…
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The PRISMA 2020 statement: An updated guideline for reporting systematic reviews Open
The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement, published in 2009, was designed to help systematic reviewers transparently report why the review was done, what the authors did, and what they found…
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Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease Open
Antiinflammatory therapy targeting the interleukin-1β innate immunity pathway with canakinumab at a dose of 150 mg every 3 months led to a significantly lower rate of recurrent cardiovascular events than placebo, independent of lipid-level…
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Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods Open
Estimates of the worldwide incidence and mortality from 36 cancers and for all cancers combined for the year 2018 are now available in the GLOBOCAN 2018 database, compiled and disseminated by the International Agency for Research on Cancer…
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First Case of 2019 Novel Coronavirus in the United States Open
An outbreak of novel coronavirus (2019-nCoV) that began in Wuhan, China, has spread rapidly, with cases now confirmed in multiple countries. We report the first case of 2019-nCoV infection confirmed in the United States and describe the id…
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Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-years for 32 Cancer Groups, 1990 to 2015 Open
As part of the epidemiological transition, cancer incidence is expected to increase in the future, further straining limited health care resources. Appropriate allocation of resources for cancer prevention, early diagnosis, and curative an…
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Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma Open
In this multicenter study, patients with refractory large B-cell lymphoma who received CAR T-cell therapy with axi-cel had high levels of durable response, with a safety profile that included myelosuppression, the cytokine release syndrome…
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Acute Abdomen: A Rare Case of Ruptured Hepatocellular Carcinoma Open
Spontaneous ruptures of hepatocellular carcinoma (HCC) are rare. Nevertheless they may lead to difficult decisions in the emergency situation. The acute therapies include conservative treatment, transarterial embolization and surgery. Cura…
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European Position Paper on Rhinosinusitis and Nasal Polyps 2020 Open
The European Position Paper on Rhinosinusitis and Nasal Polyps 2012 is the update of similar evidence based position papers published in 2005 and 2007.The document contains chapters on definitions and classification, we now also proposed d…
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SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients Open
SARS-CoV-2 Viral Load in Upper Respiratory Specimens The authors report results of an analysis of nasal and throat swabs from 17 patients in Zhuhai, China, who had received a diagnosis of Covid-19....
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Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck Open
Among patients with platinum-refractory, recurrent squamous-cell carcinoma of the head and neck, treatment with nivolumab resulted in longer overall survival than treatment with standard, single-agent therapy. (Funded by Bristol-Myers Squi…
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Transcatheter or Surgical Aortic-Valve Replacement in Intermediate-Risk Patients Open
In intermediate-risk patients, TAVR was similar to surgical aortic-valve replacement with respect to the primary end point of death or disabling stroke. (Funded by Edwards Lifesciences; PARTNER 2 ClinicalTrials.gov number, NCT01314313.).
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Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients Open
Among patients with severe aortic stenosis who were at low surgical risk, the rate of the composite of death, stroke, or rehospitalization at 1 year was significantly lower with TAVR than with surgery. (Funded by Edwards Lifesciences; PART…
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Durvalumab after Chemoradiotherapy in Stage III Non–Small-Cell Lung Cancer Open
Progression-free survival was significantly longer with durvalumab than with placebo. The secondary end points also favored durvalumab, and safety was similar between the groups. (Funded by AstraZeneca; PACIFIC ClinicalTrials.gov number, N…
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Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study Open
Objective To delineate the clinical characteristics of patients with coronavirus disease 2019 (covid-19) who died. Design Retrospective case series. Setting Tongji Hospital in Wuhan, China. Participants Among a cohort of 799 patients, 113 …
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Head and neck squamous cell carcinoma Open
Most head and neck cancers are derived from the mucosal epithelium in the oral cavity, pharynx and larynx and are known collectively as head and neck squamous cell carcinoma (HNSCC). Oral cavity and larynx cancers are generally associated …
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Empagliflozin and Progression of Kidney Disease in Type 2 Diabetes Open
In patients with type 2 diabetes at high cardiovascular risk, empagliflozin was associated with slower progression of kidney disease and lower rates of clinically relevant renal events than was placebo when added to standard care. (Funded …
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Transcatheter Aortic-Valve Replacement with a Self-Expanding Valve in Low-Risk Patients Open
In patients with severe aortic stenosis who were at low surgical risk, TAVR with a self-expanding supraannular bioprosthesis was noninferior to surgery with respect to the composite end point of death or disabling stroke at 24 months. (Fun…
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The STROBE guidelines Open
An observational study is a type of epidemiological study design, which can take the form of a cohort, a case-control, or a cross-sectional study. When presenting observational studies in manuscripts, an author needs to ascertain a clear p…
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Pembrolizumab as Second-Line Therapy for Advanced Urothelial Carcinoma Open
Pembrolizumab was associated with significantly longer overall survival (by approximately 3 months) and with a lower rate of treatment-related adverse events than chemotherapy as second-line therapy for platinum-refractory advanced urothel…
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2016 ESC/EAS Guidelines for the Management of Dyslipidaemias Open
peer reviewed
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CONSORT 2010 statement: extension to randomised pilot and feasibility trials Open
The CONSORT Statement (CONsolidated Standards for Reporting Trials) is a reporting guideline designed to improve the transparency and quality of the reporting of randomised controlled trials (RCTs). In this article, we present an extension…
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Periodontitis: Consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri‐Implant Diseases and Conditions Open
A new periodontitis classification scheme has been adopted, in which forms of the disease previously recognized as “chronic” or “aggressive” are now grouped under a single category (“periodontitis”) and are further characterized based on a…
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Surgical or Transcatheter Aortic-Valve Replacement in Intermediate-Risk Patients Open
TAVR was a noninferior alternative to surgery in patients with severe aortic stenosis at intermediate surgical risk, with a different pattern of adverse events associated with each procedure. (Funded by Medtronic; SURTAVI ClinicalTrials.go…
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Green's Operative Hand Surgery Open
Green's operative hand surgery , Green's operative hand surgery , کتابخانه مرکزی دانشگاه علوم پزشکی تهران
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Transcatheter Mitral-Valve Repair in Patients with Heart Failure Open
Among patients with heart failure who have mitral regurgitation due to left ventricular dysfunction, the prognosis is poor. Transcatheter mitral-valve repair may improve their clinical outcomes.
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Bariatric Surgery versus Intensive Medical Therapy for Diabetes — 5-Year Outcomes Open
Five-year outcome data showed that, among patients with type 2 diabetes and a BMI of 27 to 43, bariatric surgery plus intensive medical therapy was more effective than intensive medical therapy alone in decreasing, or in some cases resolvi…
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10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer Open
At a median of 10 years, prostate-cancer-specific mortality was low irrespective of the treatment assigned, with no significant difference among treatments. Surgery and radiotherapy were associated with lower incidences of disease progress…