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Breast Cancer
bioRxiv (Cold Spring Harbor Laboratory)
Hormone replacement therapy and dementia risk among postmenopausal women: evidence from the UK Biobank
2025
Abstract Importance The relationship between HRT use and dementia risk is unclear, with studies reporting both increased and decreased risk. Objective To identify modulators of the association between HRT use and dementia risk and identify potentially respons…
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Breast Cancer

Cancer that originates in mammary glands

Breast cancer is a cancer that develops from breast tissue. Signs of breast cancer may include: a lump in the breast, a change in breast shape, dimpling of the skin, milk rejection, fluid coming from the nipple, a newly inverted nipple, or a red or scaly patch of skin. In those with distant spread of the disease, there may be bone pain, swollen lymph nodes, shortness of breath, or yellow skin.

Risk factors for developing breast cancer include obesity, a lack of physical exercise, alcohol consumption, hormone replacement therapy during menopause, ionizing radiation, an early age at first menstruation, having children late in life (or not at all), older age, having a prior history of breast cancer, and a family history of breast cancer.

Exploring foci of:
bioRxiv (Cold Spring Harbor Laboratory)
Hormone replacement therapy and dementia risk among postmenopausal women: evidence from the UK Biobank
2025
Abstract Importance The relationship between HRT use and dementia risk is unclear, with studies reporting both increased and decreased risk. Objective To identify modulators of the association between HRT use and dementia risk and identify potentially responsive subgroups of women. Design, setting, and participants This study used data from the UK Biobank, with baseline assessment conducted between 2006 and 2010 and follow up through to October 2022. The cohort included post-menopausal women without a diagnosis of…
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Dementia
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