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Cell Biology
Oncology Letters • Vol 29 • No 3
Single‑cell transcriptomic analysis revealed the tumor‑associated microenvironment of papillary thyroid carcinoma with metastasis
2025
Papillary thyroid cancer (PTC) is frequently associated with inflammation and lymph node metastasis. Single-cell RNA sequencing (scRNA-seq) is a powerful tool to uncover rare cellular subpopulations and investigate the diverse functions inside tissue microenv…
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Cell Biology

Branch of biology that studies cells

Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. All organisms are made of cells. A cell is the basic unit of life that is responsible for the living and functioning of an organism. Cell biology is the study of the structural and functional units of cells. Cell biology encompasses both prokaryotic and eukaryotic cells and has many subtopics which may include the study of cell metabolism, cell communication, cell cycle, biochemistry, and cell composition. The study of cells is performed using several microscopy techniques, cell culture, and cell fractionation.

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Oncology Letters • Vol 29 • No 3
Single‑cell transcriptomic analysis revealed the tumor‑associated microenvironment of papillary thyroid carcinoma with metastasis
2025
Papillary thyroid cancer (PTC) is frequently associated with inflammation and lymph node metastasis. Single-cell RNA sequencing (scRNA-seq) is a powerful tool to uncover rare cellular subpopulations and investigate the diverse functions inside tissue microenvironments. In the present study, scRNA-seq analysis was employed to analyze the differences in macrophages, dendritic cells (DCs) and T cells between a metastatic PTC (PTC-M) and its adjacent normal tissues, as well as a PTC tumor without metastasis. The findi…
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