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Molecules • Vol 22 • No 12
A Seed Expansion Graph Clustering Method for Protein Complexes Detection in Protein Interaction Networks
2017
Most proteins perform their biological functions while interacting as complexes. The detection of protein complexes is an important task not only for understanding the relationship between functions and structures of biological network, but also for predictin…
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Computer Science

Study of computation

Computer science is the study of computation, information, and automation. Computer science spans theoretical disciplines (such as algorithms, theory of computation, and information theory) to applied disciplines (including the design and implementation of hardware and software).

Algorithms and data structures are central to computer science. The theory of computation concerns abstract models of computation and general classes of problems that can be solved using them. The fields of cryptography and computer security involve studying the means for secure communication and preventing security vulnerabilities. Computer graphics and computational geometry address the generation of images.

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Molecules • Vol 22 • No 12
A Seed Expansion Graph Clustering Method for Protein Complexes Detection in Protein Interaction Networks
2017
Most proteins perform their biological functions while interacting as complexes. The detection of protein complexes is an important task not only for understanding the relationship between functions and structures of biological network, but also for predicting the function of unknown proteins. We present a new nodal metric by integrating its local topological information. The metric reflects its representability in a larger local neighborhood to a cluster of a protein interaction (PPI) network. Based on the metric…
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