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Cortical Homunculus
bioRxiv (Cold Spring Harbor Laboratory)
Medial prefrontal cortical neurotransmitters reactive to relapse-promoting and relapse-suppressing cues in rats trained to self-administer cocaine or alcohol
2024
ABSTRACT Environmental cues conditioned to signal drug availability (S+) or omission (S-) activate specific neurons (neuronal ensembles/engram cells) within the medial prefrontal cortex (mPFC) to promote and suppress drug relapse in rats. However, the neuroch…
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Cortical Homunculus

Distorted model of the body corresponding to sensory and motor nerve density

A cortical homunculus (from Latin homunculus 'little man, miniature human') is a distorted representation of the human body, based on a neurological "map" of the areas and proportions of the human brain dedicated to processing motor functions, or sensory functions, for different parts of the body. Nerve fibres—conducting somatosensory information from all over the body—terminate in various areas of the parietal lobe in the cerebral cortex, forming a representational map of the body.

Findings from the 2010s and early 2020s began to call this interpretation into question, and research is ongoing in this field.

Exploring foci of:
bioRxiv (Cold Spring Harbor Laboratory)
Medial prefrontal cortical neurotransmitters reactive to relapse-promoting and relapse-suppressing cues in rats trained to self-administer cocaine or alcohol
2024
ABSTRACT Environmental cues conditioned to signal drug availability (S+) or omission (S-) activate specific neurons (neuronal ensembles/engram cells) within the medial prefrontal cortex (mPFC) to promote and suppress drug relapse in rats. However, the neurochemical source of such cue-specific activation remains unknown. In this study, we determined extracellular neurotransmitter fluctuations reactive to S+ vs. S- in the infralimbic (IL) and prelimbic (PL) cortices of male rats trained to lever-press for cocaine or…
Click Cortical Homunculus Vs:
Medial Pterygoid Muscle
Medial Lemniscus
Dorsolateral Prefrontal Cortex
Ventromedial Prefrontal Cortex
Medial Collateral Ligament