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Design Of Experiments
Scientific Repository (Petra Christian University)
Development and validation of bioanalytical method for amlodipine in human plasma with optimised extraction method using Design of Experiment (DOE)
2015
Amlodipine is antihypertensive drug belonging to calcium antagonist group. This study aims to apply experimental design for the optimization of extraction method of amlodipine from human plasma for higher and constant recovery. A chromatographic method involv…
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Design Of Experiments

Design of tasks

The design of experiments (DOE), also known as experiment design or experimental design , is the design of any task that aims to describe and explain the variation of information under conditions that are hypothesized to reflect the variation. The term is generally associated with experiments in which the design introduces conditions that directly affect the variation, but may also refer to the design of quasi-experiments, in which natural conditions that influence the variation are selected for observation.

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Scientific Repository (Petra Christian University)
Development and validation of bioanalytical method for amlodipine in human plasma with optimised extraction method using Design of Experiment (DOE)
2015
Amlodipine is antihypertensive drug belonging to calcium antagonist group. This study aims to apply experimental design for the optimization of extraction method of amlodipine from human plasma for higher and constant recovery. A chromatographic method involving HPLC (High Performance Liquid Chromatography) with DAD (Diode Array Detector) was developed and validated for the determination of Amlodipine in human plasma with cetirizine as internal standard. Sample preparation for the extraction of Amlodipine and Ceti…
Click Design Of Experiments Vs:
Chromatography
Extraction (Chemistry)
High-Performance Liquid Chromatography
Chemistry
Factorial Experiment
Solvent
Response Surface Methodology
Computer Science
Mathematics
Click Design Of Experiments Vs:
Machine Learning
Statistics
Blood Pressure
Medicine
Radiology
Organic Chemistry