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Embryonic Stem Cell
bioRxiv (Cold Spring Harbor Laboratory)
Coordinated multiple cellular processes in tongue development
2023
Abstract Dysfunction of primary cilia leads to genetic disorder, ciliopathies, which shows various malformations in many vital organs such as brain. Multiple tongue deformities including cleft, hamartoma and ankyloglossia are also seen in ciliopathies, which …
Article

Embryonic Stem Cell

Type of pluripotent blastocystic stem cell

Embryonic stem cells ( ESCs ) are pluripotent stem cells derived from the inner cell mass of a blastocyst, an early-stage pre-implantation embryo. Human embryos reach the blastocyst stage 4–5 days post fertilization, at which time they consist of 50–150 cells. Isolating the inner cell mass (embryoblast) using immunosurgery results in destruction of the blastocyst, a process which raises ethical issues, including whether or not embryos at the pre- implantation stage have the same moral considerations as embryos in the post- implantation stage of development.

Researchers are currently focusing heavily on the therapeutic potential of embryonic stem cells, with clinical use being the goal for many laboratories.

Exploring foci of:
bioRxiv (Cold Spring Harbor Laboratory)
Coordinated multiple cellular processes in tongue development
2023
Abstract Dysfunction of primary cilia leads to genetic disorder, ciliopathies, which shows various malformations in many vital organs such as brain. Multiple tongue deformities including cleft, hamartoma and ankyloglossia are also seen in ciliopathies, which yield difficulties in fundamental functions such as mastication and vocalization. Here, we found these tongue anomalies in mice with mutation of ciliary protein. Abnormal cranial neural crest-derived cells (CNCC) failed to evoke Hh signal for differentiation o…
Click Embryonic Stem Cell Vs:
Cilium
Biology
Cell Biology
Mesoderm
Ectoderm
Grey's Anatomy Season 18
Neuroscience
Phenotype
Embryo