A multi-site MicroLED Optrode Array for Neural Interfacing Article Swipe
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· 2018
· Open Access
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· DOI: https://doi.org/10.1101/480582
We present an electrically addressable optrode array capable of delivering light to 181 sites in the brain, each providing sufficient light to optogenetically excite hundreds of neurons in vivo , developed with the aim to allow behavioural studies in large mammals. The device is a glass microneedle array directly integrated with a custom fabricated microLED device, which delivers light to 100 needle tips and 81 interstitial surface sites, giving 2-level optogenetic excitation of neurons in vivo . Light delivery and thermal properties are evaluated, with the device capable of peak irradiances > 80 mW/mm 2 per needle at 50 ms pulse widths with tissue temperature increase less than 1 ° C. Future designs are explored through optical and thermal modelling and benchmarked against the current device.
Related Topics To Compare & Contrast
- Type
- preprint
- Language
- en
- Landing Page
- https://doi.org/10.1101/480582
- https://www.biorxiv.org/content/biorxiv/early/2018/11/29/480582.full.pdf
- OA Status
- green
- Cited By
- 8
- References
- 33
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2903407510