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BMJ • Vol 380
Transparent reporting of multivariable prediction models developed or validated using clustered data: TRIPOD-Cluster checklist
2023
The increasing availability of large combined datasets (or big data), such as those from electronic health records and from individual participant data meta-analyses, provides new opportunities and challenges for researchers developing and validating (includi…
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Engineering

Applied science

Engineering is the use of scientific principles to design and build machines, structures, and other items, including bridges, tunnels, roads, vehicles, and buildings. The discipline of engineering encompasses a broad range of more specialized fields of engineering, each with a more specific emphasis on particular areas of applied mathematics, applied science, and types of application. See glossary of engineering.

The term engineering is derived from the Latin ingenium , meaning "cleverness" and ingeniare , meaning "to contrive, devise".

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BMJ • Vol 380
Transparent reporting of multivariable prediction models developed or validated using clustered data: TRIPOD-Cluster checklist
2023
The increasing availability of large combined datasets (or big data), such as those from electronic health records and from individual participant data meta-analyses, provides new opportunities and challenges for researchers developing and validating (including updating) prediction models. These datasets typically include individuals from multiple clusters (such as multiple centres, geographical locations, or different studies). Accounting for clustering is important to avoid misleading conclusions and enables res…
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