Tailor‐Made Autophagy Cascade Amplification Polymeric Nanoparticles for Enhanced Tumor Immunotherapy (Small 24/2023) Article Swipe

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autophagy epirubicin immunotherapy nanoparticle materials science nanotechnology cancer research programmed cell death immunogenic cell death chemistry immune system medicine apoptosis immunology biochemistry chemotherapy internal medicine cyclophosphamide

Xuehua Long , Huiqi Wang , Jianqin Yan , Yifei Li , Xue Dong , Sijia Tian , Yong Sun , Kui Luo , Bin He , Yan Liang ·

YOU? · · 2023 · Open Access · · DOI: https://doi.org/10.1002/smll.202370172 · OA: W4380610367

Enhanced Tumor Immunotherapies Tailor-made polymeric nanoparticles with the function of autophagy cascade amplification due to the co-delivery of autophagy inducer STF-62247 and antitumor drug epirubicin, which could assist cell uptake and tumor penetration with the help of arginine and promote immunogenic cell death by the enhancement of autophagy for the best tumor immunotherapy effect. More details can be found in article number 2207898 by Yong Sun, Yan Liang, and co-workers.